... studied andof the structural appearance of the extracellular matrix in adjacent histological sections In addition, some evidence for a later change of gene expression of MMP13, aggrecan and tenascinC ... of OA progression characterized by further upregulation of MMP13 and tenascinC From a clinical point of view, the possibility of differentiating successive stages of OA progression by means of ... objectives of this project was to focus on local aspects of gene expression with reference to the histologicalgradingof cartilage degeneration Most strikingly, upregulation of col II, col I and YKL40...
... acquisition and analysis, participated in ANN simulations and wrote the manuscript MK developed software and performed the ANN simulations, and contributed in revision of the manuscript TS and AHR ... magnetic resonance imagingbased assessment of vascular changes and radiation response in androgen-sensitive prostate carcinoma xenografts under androgenexposed and androgen-deprived conditions Neoplasia ... therapy response (V30) Tumor volumes 32 tumors Measured therapy response (V30) Figure Schematic synopsis of the study Androgen-sensitive prostate carcinoma xenografts received combinations of androgendeprivation...
... -3’) and a reverse primer (5’-AAG GCA TGT ATG TTG GCC TC-3’) The reaction mixture of 25 μL contained 50 ng of genomic DNA, 0.5 μL of each primer, 12.5 μL of the green master mix, and 1.5-9.5 μL of ... CT and TT) and alleles (C and T) with patient’s baseline characteristics including patient’s age, gender, specimen histology, stage of the disease and presence or absence of B-symptoms (Table and ... stage and presence or absence of Bsymptoms (Table 5) None of these factors were associated with clinical response in HL patients (P value > 0.05) Table shows the genotype and allele frequencies of...
... University of Queensland, School of Medicine, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Queensland 4102, Australia 15Gastrointestinal and Liver Unit, Prince of Wales Hospital and University ... University of Turin, Sacha Stelzer-Braid and Shona Fletcher from Prince of Wales Hospital; Tanya Applegate and Jason Grebely from the National Centre in HIV Epidemiology and Clinical Research and Mandvi ... breaking up of the large haplotype block and thus allowing inference of the relative effects of each SNP The task of demonstrating the basis for causality, even of haplotypes, is not trivial, and thus...
... predictionand outcome) and (discordant predictionand outcome); a predictionof 50% has a score of 0.25 both when the outcome is or [42] The development and assessment of prognostic models based ... of bacterial infection and inflammation; the atrial-natriuretic peptide proANP and proET-1 as markers of cardiac and endothelial function, and the vasopressin precursor copeptin as a marker of ... without imputation of missing data are 1.61 (1.13 to 2.31; P = 0.01) for the predictionof serious complications and 1.65 (0.97 to 2.79; P = 0.06) for the predictionof death ness of fit test) The...
... application rates of 0.5 wt% and 1.0 wt% Alkali soil and gypsum were mixed uniformly and were packed in an acrylic ring with an outer diameter of 60 mm, inner diameter of 50 mm, and height of 20 mm at ... conductivity and the transport of salts such as cations (Na+, Ca2+, Mg2+ and K+) and Cl- in a column were investigated by using a tensiometer and a four-electrode sensor, and the amounts of these ... of the soil in the center of the column The inner and outer diameters of the stainless steel rods were mm and 16 mm, respectively, and the ratio (I/V2) of the current of an outer electrode (I)...
... and optimization of fuel cells, improve long-term performance and lifetime, the introduction of cheaper materials and fabrication techniques, and the design and development of novel architectures ... displacement, and the degree of the deformation in MEA are directly related to the increasing of current density, due to increasing of heat generation This result may explain the occurrence of cracks and ... applications, and the durability of fuel cell stack components remains, in most cases, insufficiently understood Lengthy required testing times, lack of understanding of most degradation mechanisms, and...
... Ecosystem of West Lake The ecosystem of West Lake is rather diverse with 232 species of plant, 141 species of phytoplankton, 43 species of zooplankton, 11 species of benthos and about 33 species of ... Journal of Science, Earth Sciences, T.XXIII, N0 1, 2007 Estimation andpredictionof eutrophication in West Lake 47 of nutrients loading to lakes However, the exporting coefficients and the classification ... rate of grazing phytoplankton by zooplankton; Up: rate of settlement, Mp: rate of mortality without zooplankton After combining the data of West Lake and CLEAN model, we used Stella II software...
... classified correctly in 85% of cases and Table Effect of cut-off value on the prediction accuracy The prediction accuracy, specificity, sensitivity, number of mutants classified and MCC values on training ... advantage of p53 mutation analysis, and a unique feature of this database, is the availability of the residual activity of the majority of p53 missense mutants The biological activity of mutant ... domain of the protein and were used for training and evaluation of our prediction algorithm Of the eight promoters, we studied the WAF1 promoter in greatest detail with additional testing and usage...
... properties to Program Offices (e.g., Office of Water, Office of Solid Waste and Emergency Response, Office of Prevention, Pesticides and Toxic Substances) and Regional Offices Also, SPARC has been used ... (Independent of the property, C and S), and reaction center susceptibility, which rates the responseof C to the effect in question (depends on the property, independent of S and R) The contributions of ... databases The strength of the electrostatic interaction between S and C depends on the magnitude and relative orientation of the local fields of S and C and the dielectric properties and distances through...
... 2006 FEBS 1181 Predictionof coenzyme specificity Y Kallberg and B Persson Fig Overview of the novel prediction method Sample sequences of Rossmann-fold motif are shown (top right) a and b denotes ... 2006 FEBS Y Kallberg and B Persson Predictionof coenzyme specificity our study demonstrates the power of sequence-based predictions It is our hope and belief that the presented prediction tool will ... FEBS Y Kallberg and B Persson Predictionof coenzyme specificity coenzyme binding proteins than the others (655 and 646, respectively), but given the size of their genomes ($61 000 and $53 000) the...
... sources of phosphorus include: 1) Diffuse sources: 117 - The amount of P loads from basin (P1) is related to the type of land, land use and intensive cultivation of agricultural land - The amount of ... amount of nutrients loading from basin; X1,X2, ,Xn: areas of the forms of land use and the land use methods 1, 2, ,n; a1,a2, ,an: exporting coefficients of phosphorus 2) Point sources: the amount of ... Fig Dynamic of PC, PD, PS, Pzoo in 12 months Fig Dynamic of PB, PE, PiN in 12 months Table Decrease of Cpl, PS, and content of PS Decreases of Cpl (%) Decreases of PS (%) Content of PS (mg/l)...
... LAGRANGIAN ANALYSIS ANDPREDICTIONOF COASTAL AND OCEAN DYNAMICS Written by a group of international experts in their field, this book is a review of Lagrangian observation, analysis and assimilation ... Patrick Fagan LAGRANGIAN ANALYSIS ANDPREDICTIONOF COASTAL AND OCEAN DYNAMICS Edited by ANNALISA GRIFFA Rosenstiel School of Marine and Atmospheric Science University of Miami Istituto di Scienze ... University of Delaware ARTHUR J MARIANO Rosenstiel School of Marine and Atmospheric Science University of Miami ¨ ¨ TAMAY M OZG OKMEN Rosenstiel School of Marine and Atmospheric Science University of...
... examinations, and was involved in drafting of the paper RS was involved in data collection and drafting of the paper FR was involved in data analysis and drafting of the paper AN analysed the data and ... tuberculosis andpredictionof disease in Portuguese healthcare workers Journal of Occupational Medicine and Toxicology 2011 6:19 Submit your next manuscript to BioMed Central and take full advantage of: ... (52.4%) and nurses (48.6%) had the highest rates of TST+/IGRA- discordant results Page of Fifty-seven HCWs (2.0%) had a history of active TB disease since 2005 and were treated accordingly Of these,...
... MF1 and input2 is MF1 andand input4 is MF1, then output = ~1 :Y c ~ If input1 is MF1 and input2 is MF1 andand input4 is MF2, then output = ~2 :Y c ~ If input1 is MF1 and input2 is MF1 andand ... MF1 and input2 is MF1 andand input4 is MF2, then output = ~4 :Y c ~ If input1 is MF1 and input2 is MF2 andand input4 is MF1, then output = ~5 :Y c ~ If input1 is MF1 and input2 is MF2 andand ... MF1 and input2 is MF2 andand input4 is MF1, then output = ~7 :Y c ~ If input1 is MF1 and input2 is MF2 andand input4 is MF2, then output = ~8 :Y c ~ If input1 is MF2 and input2 is MF1 and and...
... (black line) and B24 (red line) Below Density of states and HOMO (in the inset) for Coronene 161 Table Energies and percentual contributes of pz orbitals to the composition of HOMO, LUMO and their ... basis of stability for boron planar clusters Szwacki et al [15] have discussed about the regions of aromaticity of borozene and since this molecule can be indicated as the embryo of B6 and B24, ... GAP values obtained for B6 and B24 are 1.33 and 1.17 eV, respectively; their density of states (DOS) as a function of energy (eV) is shown in Fig At energy E the density of states is written as...
... coder of order 20 and with BITSA bits of quantization for each sample of the residual In many cases, the first 100 milliseconds of the excitation contains enough information about the pluck and ... decomposition of the excitation into attack and decay components for the first topology, as formerly proposed by Smith [19] and implemented by V¨ lim¨ ki and Tolonen in [13], reflects the a a wideband and ... milliseconds of the excitation and then decayed as the second half of a Hanning window for the following 100 milliseconds An example of this windowed excitation can be seen in the top of Figure...
... have a class, a name, and a specification of which kind of peptide the acid is part of Here, S means that the amino acid is part of the signal peptide while C and M are parts of the mature protein; ... one for a perfect prediction, minus one for a total opposite prediction, and zero for a completely random prediction The variables Ntp , Ntn , Nfp , and Nfn represent the number of correctly classified ... subsidiary of Swedish telecom Dr Nordin is a Cofounder of Dacapo AB, a Swedish consulting and research company specialised in the stateof-the-art information technology, and an Inventor of the patented...
... drug-target and related networks, for predicting new drug targets, and to get around unwanted resistance and side effects of drugs These tools promise to increase the number of novel drug targets and ... tool for the organization of the expanding drug-development data and give us a global view on major trends and limitations The advent of combinatorial therapies [2-4] and multi-target drugs [5] ... Nacher and Schwartz [8] computed several measures of network ‘centrality’ characterizing the importance of the drugs in the network context of various therapies They identified a subnetwork of the...
... al, in press) and we present additional results to illustrate the biology of flowering and fruiting in oaks Ecologists often call the phenomenon producing good crops some years and poor crops ... apparently viable Our estimates of total crop size are based on the number of mature acorns produced by the entire canopy of a tree as a function of the percentage of the canopy sampled by our collection ... our collection traps = In early May and late August of each year, counted the density of flowers on the outer 75 cm of upper canopy branches/tree by means of a truck with a hydraulically-raised...