high silica zeolites of the ferrierite family
Tài liệu Báo cáo khoa học: SREBPs: physiology and pathophysiology of the SREBP family ppt
Ngày tải lên :
18/02/2014, 13:20
... and pathophysiology of the SREBP family H Shimano at G1 [19] In particular, p21 is a direct target of SREBP [20] The role of SREBP-1a in the regulation of cell growth and the cell cycle might ... Physiology and pathophysiology of the SREBP family SREBP-1c and lipogenesis The SREBP family consists of three isoforms: SREBP1a, SREBP-1c, and SREBP-2 Each isoform has a different regulatory ... resistance [48] The exact roles of SREBP-1c ⁄ ADD1 are not yet fully defined SREBP and parasympathetic function in heart Parasympathetic stimulation of the heart involves activation of GIRK1 ⁄ 4,...
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Tài liệu Báo cáo khoa học: Proteasome involvement in the degradation of the Gq family of Ga subunits pptx
Ngày tải lên :
20/02/2014, 03:20
... activation of Ga16 and Gaq subunits Therefore the lack of change in the rate of degradation cannot be due to lack of receptor-activation of the alpha subunits Given that the activation of G proteins ... Accordingly, the levels of Ga16 decay were the same in the presence or absence of carbachol (Fig 4C) in cells expressing the M2R Also the activated mutant of A B C D Fig Functional assay of the Ga ... forms of Gaq and Ga16 have the same behavior as the wild-type forms argues in favor of the need of other proteins to stabilize the proteins in the membrane The interaction of Ga subunits with Gbc...
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Tài liệu Báo cáo khoa học: Characterization of the promoter for the mouse a3 integrin gene Involvement of the Ets-family of transcription factors in the promoter activity doc
Ngày tải lên :
21/02/2014, 03:20
... factor of the Ets -family is involved in the regulation The members of the Ets -family of transcription factors bind to specific purine-rich sequences with a core motif of GGAA/T and control the expression ... CCAAT box at 324 bp upstream of the major transcription start site The presence of a CCAAT box and the absence of a TATA box seem to be one of the characteristics of the mouse integrin a3 gene ... and the sets of primers listed in Table After the PCR products were digested with KpnI and SacI, the fragments were inserted into the KpnI/SacI site of Fig Structures of the 5¢-flanking region of...
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Báo cáo khoa học: Secondary transporters of the 2HCT family contain two homologous domains with inverted membrane topology and trans re-entrant loops docx
Ngày tải lên :
07/03/2014, 17:20
... ‘filtering’ of the blast searches strongly improves the specificity of the search (the ratio of true over false hits) but at the expense of much of the sensitivity of the search (the number of observed ... affinity for the coion by one order of magnitude [20] The functional importance of the region is in line with the high degree of conservation of the amino acid sequence, while the presence of a high ... N- and C-terminal halves of the OPA family is an order of magnitude higher and 25% of the hits have E-values of pE ‡ The OPA family is in the MFS whose members consist of two homologous domains...
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Báo cáo Y học: Properties of group I allergens from grass pollen and their relation to cathepsin B, a member of the C1 family of cysteine proteinases pdf
Ngày tải lên :
08/03/2014, 22:20
... parasites of the genus Giardia are one of the earliest lineages of eukaryotic cells, and the Giardia protease is the earliest known branch of the cathepsin B family [23] Its phylogeny confirms that the ... concentrating the allergen according to the isoelectric point (pI) of the molecule A pH gradient from to 11 was established for the characterization of Phl p After completion of the run, the individual ... further explore the biochemical function of group I allergens Expression of glycosylated and nonglycosylated rPhl p reveals differing stability of these allergens The expression of rPhl p in the...
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Báo cáo khoa học: A structural overview of the PDI family of proteins docx
Ngày tải lên :
15/03/2014, 23:20
... Specifically, the side chains of Leu343 and Trp347, which are part of the linker between the b¢ and a¢ domains, are inserted into the PDI family of proteins hydrophobic cavity of the b¢ domain The binding ... Representation of the full-length ERp57 structure with the region recognized as the x-linker colored in red (B) The N-terminal part of the x-linker folds against the b¢ domain in the structures of the ERp57 ... conformations in the structures of the isolated b¢ domain and full-length proteins In the crystal structure of the b¢x fragment of human PDI, the C-terminal part of the x-linker turns back to contact the...
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Báo cáo khoa học: Characterization of ubiquitin-like polypeptide acceptor protein, a novel pro-apoptotic member of the Bcl2 family pptx
Ngày tải lên :
17/03/2014, 10:20
... performed immunoblotting of the 33.5 kDa Ubi-L adduct using an antibody against synthetic peptide based on the sequence of Bcl-G The results of the Fig Primary structure of Bcl-G (A) The predicted amino ... the gene products of Bcl-G and Ubi-L The fourth column indicates the number of the first and last amino acid of the identified Bcl-G and Ubi-L peptides, whereas the fifth shows the corresponding ... bonds between the C terminal of the glycine residue of Ubi-L and the lysine of Bcl-G The 33.5 kDa Ubi-L adduct was digested by V8 protease and subjected to MALDI-MS analysis The data in the first column...
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Báo cáo khoa học: New members of the brachyurins family in lobster include a trypsin-like enzyme with amino acid substitutions in the substrate-binding pocket potx
Ngày tải lên :
23/03/2014, 03:20
... modelling The aim of the present work was to study the diversity of trypsins in the digestive gland of P argus, with focus on: (a) the position of lobster trypsins within the brachyurins family ... from the 3¢ UTR region of PaTry2 However, the 3¢ UTR sequence of PaTry4 differed to those of the other trypsins in more than 36% of its nucleotides All ORFs started at the first ATG codon of the ... the wall of the binding pocket and allow the access of bulky residues, like Arg and Lys, whereas the basic side chain of these residues is stabilized by Asp189 (chymotrypsin numbering) near the...
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Báo cáo khoa học: A hydrophobic segment within the C-terminal domain is essential for both client-binding and dimer formation of the HSP90-family molecular chaperone pptx
Ngày tải lên :
23/03/2014, 20:22
... required for the interaction with the middle domain, which mediates the dimerization of HSP90, and the other, the identification of the minimal region of the C-terminal domain for the client binding ... closely related to the client-binding function of the proteins [32,38] Taken together, we assumed that formation of the complex of the region carrying the hydrophobic segment of GRP94 is mediated ... explain the lack of the binding of the C-terminal domain of HtpG to a client protein [17] We critically reviewed the previous study that demonstrated dimer formation of the hydrophobic segment of...
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Báo cáo khoa học: The yeast stress response Role of the Yap family of b-ZIP transcription factors The PABMB Lecture delivered on 30 June 2004 at the 29th FEBS Congress in Warsaw potx
Ngày tải lên :
30/03/2014, 16:20
... with activation of FRM2 transcription, but also with growth in increasing concentrations of cadmium but not of H2O2 Because of the high degree of homology to Yap1, the role of the Yap2 cysteine ... the formation of an intermolecular bond occurs between the Orp1 Cys36 and the Cys598 of Yap1 leading to its activation The subsequent formation of the Yap1 Cys303-Cys598 disulfide bond masks the ... expression, often with overlapping functions [47] In all, the expression of 10% of the yeast the genome is affected by an osmotic upshift This includes most of the genes typically induced by the ESR,...
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báo cáo hóa học: " A psychometric evaluation of the PedsQL™ Family Impact Module in parents of children with sickle cell disease" pptx
Ngày tải lên :
18/06/2014, 18:20
... school functioning The total score is comprised of the average of all items in the questionnaire The psychosocial summary score is comprised of the average of the items in the emotional, social, ... and family functioning summary score The total score is comprised of the average of the responses to all items in the questionnaire The parent HRQL summary score is determined by averaging the ... whether the Family Impact Module is a valid and reliable measure for assessing the impact of SCD on parents and families We therefore analyzed the following properties of the PedsQL™ Family Impact...
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Báo cáo khoa học: "A case of high-grade leiomyosarcoma of the bladder with delayed onset and very poor prognosis" pptx
Ngày tải lên :
09/08/2014, 03:21
... present A hypoplasia of the left kidney was also reported No other metastasis was reported in the abdomino-pelvic cavity Pielography showed a delay in the opacification of the renal pelvis associated ... eventually, a bleeding lesion onto the bladder wall that raised suspicion of neoplastic invasion The lesion appeared more likely as a loss of continuity of the urothelial mucosa; an ulcerating mass ... was therefore delayed, due on the fact that the patient had no symptoms until tumor reached an advanced stage and became locally invasive The patient, otherwise being Figure Leiomyosarcoma of the...
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Báo cáo y học: "High synovial expression of the inhibitory FcγRIIb in rheumatoid arthritis" ppsx
Ngày tải lên :
09/08/2014, 10:20
... confirms the results of the immunofluorescence stainings Furthermore, we observed that FcγRpositive cells, most likely macrophages, often co-localised with CD3-positive T cells around vessels of the ... expression of the inhibitory FcγRIIb, as well as of the activating FcγRI, FcγRII and FcγRIII, is increased in RA synovium, regardless of disease duration The importance of FcγRI and FcγRIIb in the synovial ... contributions SK and A-KU were the initiators of the study SK, SEM, A-KU and ME planned the experiments together SEM performed all experiments ME did the tissue sectioning of the biopsies Immunohistochemistry...
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Báo cáo y học: "Differential expression of the FAK family kinases in rheumatoid arthritis and osteoarthritis synovial tissues" doc
Ngày tải lên :
09/08/2014, 10:21
... immunoreactive The number of cells of a given type that reacted with a specific antibody divided by the total number of cells of that given type was defined as the percentage of reactivity The mean ... responsible for acquisition of data; AEK was responsible for design of the study, interpretation of the data and manuscript preparation, and all authors have approved the content of the manuscript Acknowledgements ... that they have no competing interests Authors' contributions SS was responsible for design of the study, acquisition of data, analysis and interpretation of the data and manuscript Page of 10...
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Báo cáo y học: "Immunostaining of modified histones defines high-level features of the human metaphase epigenome" potx
Ngày tải lên :
09/08/2014, 22:23
... H3K27me3 is clearly different The results suggest that there is extensive remodeling of the epigenome as cells enter mitosis, but that a high- level memory of some components of the interphase epigenome ... clusters and their control elements A crucial question is whether the bands have any functional significance in their own right, or whether they passively reflect the net level of histone modification ... serving to enhance the banding pattern in metaphase Taken together, these Page 11 of 14 findings suggest that there is widespread remodeling of the epigenome during mitosis The enzymatic mechanisms...
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Báo cáo y học: ": Immunostaining of modified histones defines high-level features of the human metaphase epigenome" pot
Ngày tải lên :
09/08/2014, 22:23
... H3K27me3 is clearly different The results suggest that there is extensive remodeling of the epigenome as cells enter mitosis, but that a high- level memory of some components of the interphase epigenome ... clusters and their control elements A crucial question is whether the bands have any functional significance in their own right, or whether they passively reflect the net level of histone modification ... serving to enhance the banding pattern in metaphase Taken together, these Page 11 of 14 findings suggest that there is widespread remodeling of the epigenome during mitosis The enzymatic mechanisms...
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Retrovirology Short report BioMed Central Open Access High level expression of the ppsx
Ngày tải lên :
12/08/2014, 23:20
... FACS-analysis of GFP (data not shown) that is expressed from a second reading frame of the mRNA of the transgene [24] Inhibition of the p38 phosphorylation by either stable overexpression of the dominant-negative ... Garcia-Sastre A: Cellular transcriptional profiling in influenza A virusinfected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential ... form of MKK6 (Figure 2A) or application of the p38 inhibitor SB203580 (20 μM) (data not shown) did not affect the induced transcription of APOBEC3G These findings argue against a prominent role of...
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EXPRESSION AND FUNCTION OF THE PRL FAMILY OF PROTEIN TYROSINE PHOSPHATASE
Ngày tải lên :
24/08/2014, 11:44
... in the vascular endothelial cells, fibroblasts, and lymphocytes of the choroids, in the corneal epithelium and endothelium, and in the fibroblasts of the cornea and sclera In the corneal epithelium, ... our current understanding of the expression and function of the PRL family of enzymes as well as of the role these important signaling molecules play in the progression of human disease PUBLICATIONS ... of Thesis/Dissertation: Expression and Function of the PRL Family of Protein Tyrosine Phosphatase For the degree of Doctor of Philosophy Choose your degree I certify that in the preparation of...
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synthesis of high-silica aluminosilicate zeolites
Ngày tải lên :
31/05/2014, 02:07
... 14 Synthesis * General comments * References PART II CHAPTER I of of of of of of of of of of of of of of ZSM-34 ferrieritejZSM-35-type materials ZSM-39 high- silica ZSM-6 with TMA high- silica ... synthesis of high- silica zeolites * Specific recipes Synthesis Synthesis Synthesis Synthesis Synthesis Synthesis Synthesis Synthesis Synthesis 10 Synthesis 11 Synthesis 12 Synthesis 13 Synthesis ... crystallization of the MFI * * * * * * * * structure The Si0 2A1 203 ratio of the gel The TPA/Si0 ratio of the gel The degree of dilution or the H 20/Si0 ratio The M/Si0 ratio The OH/Si0 ratio The nature of...
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Báo cáo y học: " Experimental ablation of the pancreas with high intensity focused ultrasound (HIFU) in a porcine model"
Ngày tải lên :
25/10/2012, 11:18
... monitoring the energy deposition and the therapeutic effect, and also controlling the US exposure based on the feedback digital data from the ultrasonograms in the process of HIFU treatment The therapeutic ... leading the coagulation necrosis of the whole target regions During the therapeutic process, real-time estimation of the therapeutic effect was carried out by the computer system through the graphic ... transducer and the skin in order to well locate the target region The real-time US imaging device was used to locate the head of pancreas as the pre-designed target region The spatial volumes of the target...
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