... phosphate and, in particular glycerol 3-phosphate (Gro-3-P), whereas ATP concentrations fell The extent of these changes andthe rate of glycerol uptake and glucose synthesis were dependent on the ... inulin and 10 mU inulinase either alone (j) or together with an infusion of glycerol at 0.138 0.006 lmolámin)1 (d) for periods up to 60 The ®gure shows the change in the amount of glucose in the ... intracellularly The enzymes all have high activity in liver and are thought to keep the mass± action ratio of their substrates close to equilibrium [3] .The conventional view is that the substrate pools of these...
... [30], and angiogenesis [18,31] Therefore, the fact that RVL completely abrogated the increase of hepatic blood IL-18 induced by tumorderived factors suggests the potential use of RVL as a hepatic ... expression on thehepatic microvasculature which decreased by 50% the microvascular retention of melanoma cells in the liver; and third, it prevented melanoma cell responses to hepatic IL-18, further ... conceived of the study, participated in its design and coordination, and wrote this manuscript All authors have read and approved the final manuscript Competing interests The authors declare that they...
... drafted the manuscript, WF and DM participated in the design of the study, NEM and AyS assisted with the collection of data and conceived of the study, MK and AlS participated in the design and coordination ... young age distribution and no evidence of immunosuppression These cases highlight the diagnostic and therapeutic challenges of this rare tumour We have reviewed the literature and discussed treatment ... tacrolimus to sirolimus andthe patient survived for an additional 20 months before dying of extensive metastatic disease [21] The interplay between immunosuppression andthe development and progression...
... NCB, PC and FS analyzed and interpreted the data and wrote the manuscript ST performed the stent placement andthe arteriography PM and CDB were major contributors in writing and correcting the manuscript ... angiography of the superior mesenteric artery after the placement of a metallic endoprosthesis (A) The lateral arteriogram shows the final position of the endoprosthesis at the proximal part of the superior ... (white arrows) The small bowel andthe colon have a normal appearance (C) The curved multi-planar reconstruction along the main trunk of the superior mesenteric artery shows the origin of the dissection...
... regarding the presence of hepaticvein stenosis, multiplanar reconstruction (MPR) images and three-dimensional CT images were also assessed, andthe stenosis at the root of the left hepaticvein was ... was measured Hepatic venous catheterization was performed through the jugular veinThe mean hepatic venous pressure was 15.6 mmHg, andthe pressure abruptly decreased when the catheter was pulled ... placed into the left hepaticvein via the internal jugular vein Because the large umbilical fissure vein was bifurcated just behind the stenosis, another metallic stent with a diameter of mm and a...
... tumour thrombus in the internal jugular vein or the great veins of the neck [7] The tumour thrombus is the result of a tumour extension from the thyroid gland to the IJV or the result of occult ... follicular cells if there was poor communication andthe reporting pathologist was not made aware that the initial aspirate was from the parotid gland and not from the thyroid gland Abbreviations ... Involvement of the parotid gland by invasion or spread by metastases from malignant tumours in the head and neck is uncommon, with the exception of melanoma of the temple, scalp and ear, and anaplastic...
... lesions were located in the right hepatic lobe and multiple smaller ones in the caudate and left lobe All these hepatic lesions were consistent with the features of hemangiomas The CT scan also showed ... hemangioma-like formation in the left abdomen It was difficult to determine whether this originated from the spleen or from the left adrenal gland, and a large cyst of the right ovary, suspicious ... vessels (Figure 3) The internal surface of the ovarian cyst was lined with cylindrical endometrial epithelium and with endometrial stroma and occasional endometrial glands underneath The histological...
... govern the response to hormones and mediators, which further influence the response to nutrients themselves Although our results may be heavily influenced by the design of the experiment andthe ... cytokines andthe GH–IGF-I axis Authors' contributions MJO'L and RCS conceived of and designed the study All authors participated in the animal handling and procedures CJS carried out the immunoassays ... changes at the level of the mucosa of the gastrointestinal tract In mice, the presence or absence of nutrients within the gut lumen has a major influence on the size and function of the gut mucosal...
... cells Endothelial-tumor cell interactions induce nitric oxide release from thehepatic endothelium Direct and indirect evidence from the literature has supported the hypothesis that thehepatic ... to lead to the increased tumor cell binding and stimulation of angiogenesis, and on the other hand, endothelial cells can contribute to host anti-metastatic responses by producing the cytotoxic ... influence the interactions between metastatic tumor cells andthe liver with a consequence of altering the formation of liver metastases In addition, thehepatic endothelial adhesive and cytotoxic...
... class diagram shows the existence of classes and their relationships in the logical view of a system UML modeling elements in class diagrams - Classes and their structure and behavior - Association, ... provide to the actor when the use cases is executed Typical contents - How the use case starts and ends Normal flow of events Alternate flow of events Exceptional flow of events 10 Uses and Extends ... and its subclasses There are two ways to find inheritance: - Generalization - Specialization Common attributes, operations, and/ or relationships are shown at the highest applicable level in the...
... to the toiling and dying types who made it over to America And once in America, people divided once again: you could say they became the poor andthe rich The losers and winners The artists and ... narrative structure, and to the kind of stories that get told and retold about the Irish, so as to reveal both the regularity of English colonial discourse on Ireland andthe Irish andthe mutations ... take up and extend Said’s insight, in Culture and Imperialism, that the ‘‘convergence between the patterns of narrative authority constitutive of the novel on the one hand, and, on the other, a...
... on these estates The other contingent lacked the unity of the Richmond tenants These were Bretons from the north-east of the duchy who received grants of land in the midlands, the south-west and ... ± The barons of Leon and Penthievre could construct forti®cations without the permission of the duke;  Á ± The barons of Leon and Penthievre had the right of wreck on the shores of their lands; ... Blain andthe à forest of Le Gavre.24 South of the Loire, ducal domains included the castellany of Le Pallet,25 estates on the south bank of the Loire and another in the extreme south-west of the...
... Night andthe following day, they were ‘‘everyone’’ and ‘‘London’’ and even ‘‘England.’’ They were created as a group by the newspapers, and this chapter examines the mechanism of their creation and ... the food stocks, andthe mood of the garrison The tactics of the Daily Mail captured the attention of the nation; the newspaper dramatized the situation of the town by emphasizing the danger that ... don’t know they know the public’’ (quoted in Koss Rise and Fall ) The Victorian cult of personality had moved into the press by the turn of the century, andthe military version of the focus...
... the Netherlands, Luxembourg, Switzerland, north-east Spain and northern and papal Italy – are clearly within the Western and European purview.7 Ancient Greek philosophy, Jewish spirituality and ... on the mountain There is the hint in the Rembrandt that the seventeenth-century interpretation of Moses had him invested with more personal agency in the carriage of the laws; neither God nor the ... the rise of the state 6.1 The birth of the state 6.2 Legal diversity and universality in the emerging European states 6.3 The decline of the Christian commonwealth 6.4 The arrival of the state...
... Sinbad the Sailor Poe andthe printed word and Jack andthe Beanstalk; new London editions of these two works appeared the year the Allan family came to England.3 So did new editions of The History ... the Rotunda: ``They have nearly ®nished the Rotunda ± The pillars of the Portico are completed and it greatly improves the appearance of the whole ± The books are removed into the library ± and ... from the form of their original publication, and these removals affect interpretation The appearance of the printed page, however, shapes the reader's understanding of the text it contains ``The...
... variety of approaches They examine the structure of the press; the methods used to control it by political authorities and their effectiveness; the journalistic texts themselves; andthe political role ... texts, their presentation and format, the topics they covered, the way issues were presented andthe messages, overt and implicit, that they contained Such a comprehensive approach to the comparative ... political press was the product of the struggles for independence from Britain and to forge a new nation, and in the Netherlands, the outcome of the Patriot Revolution of the s In France...
... conservative propaganda, and with the break up of the radical associations andthe consequent erosion of the links between these organisations and other intellectual currents and circles, the conditions ... of the age The complex intersection of these two histories – the political turmoil of the 1790s andthe broader hegemonic shift towards the meritocratic bias of the professional classes – demands ... Wordsworth’s observation gathers together fears about the French Revolution, the Industrial Revolution, and 10 The Crisis of Literature in the 1790s the information revolution ( the rapid communication...
... taken, the straight between the points either all fall on the same side of the surface, or some on the same side, and some on itself, but none on the other side /5/ And, when ... the center of the sphere, I call the figure internally contained by the surface of the cone, and by the surface of the sphere inside the cone, a “solid sector.” /6/ And when two cones having the ... direction and either one of them is wholly contained by the other and by the straight having the same limits as itself, or some is contained, and some it has common; andthe contained...
... individual, hand-to-hand combat Grand strategy, on the other hand, remained the preserve of Tiw.11 In India, too, much the same phenomenon was apparent in the role of Indra, the chief of the Vedic ... negative, then the process was repeated, and a second mission sent This time, the Aztec ambassadors anointed the right arm and head of the other ruler, set a tuft of feathers on his head and gave ... formal demands to the other side and then to inform the other side straight away that Rome was making war against it in the event of their rejection.58 The obsolescence of the fetial procedure...