... Molecular Imaging and Contrast Agent Database (MICAD): Evolution and Progress [Internet] Mol Imaging Biol Oct 12 Comar, D., Cartron J.C., Maziere M & Marazano, C 1976 Labelling and metabolism of ... or 11C-acetate, and 18F- or 11Ccholine J Nucl Med 52: 81-9 Janicki, S.M., Tsukamoto T., Salghetti S.E., Tansey W.P., Sachidanandam R., Prasanth K.V., Ried T., Shav-Tal Y., Bertrand E., Singer ... on green fluorescent proteins and calmodulin Nature 388: 882-887 Muller, W.G., Walker D., Hager G.L., and McNally J.G 2001 Large-scale chromatin decondensation and recondensation regulated by...
... generated in plants and its relationship with the elicitation of defense responses carried out by oligosaccharides, and particularly, by oligoglucans 2 Cell Metabolism – Cell Homeostasisand Stress Response ... soluble proteins, proline, ascorbate and glutathione, and antioxidant enzymes (Reddy et al., 2005) On the other hand, processes related to the deterioration of fruits and vegetables, either by attack ... chloroplasmatic APX (in the stroma and thylakoid) (Ishikawa et al., 1996) and mitochondrial (De Leonardis et al., 2000) Each one, Cell Metabolism – Cell Homeostasisand Stress Response with a specific...
... peroxidases and catalases 16 Cell Metabolism – Cell Homeostasisand Stress Response The analysis of differential gene expression and analysis of global patterns of gene expression using macro and microarray ... Cell Homeostasisand Stress Response both by plant roots (ethanol and acetaldehyde) and the metabolism of anaerobic microorganisms (methane, ethane, unsaturated acids, aldehydes, ketones), and ... availability of Zn and Cu and the formation of hydrogen sulfide and organic acids (Camargo et al., 1999) This soil is also characterized by accumulating a larger amount of CO2 (Jackson, 2004) and stimulate...
... 79, pp 3-20, ISSN 0305-7364 Vinit-Dunand, F.; Epron, D.; Alaoui-Sosse, B & Badot, P.M (2002) Effects of copper on growth and on photosynthesis of mature and expanding leaves in cucumber plant Plant ... Cell Homeostasisand Stress Response This reaction can also be catalyzed by univalent cuprous ion, which is oxidized to divalent ion Both the oxidized iron and cuprum can be re-reduced by O2•−, and ... preferably attacks the thimines and cytosines, and in a less extent, adenines, guanines, and the rest of desoxyribose (Cadet et al., 1999) O2•− has weaker effects on the DNA, and attacks preferably guanines...
... Bcl-w, Bcl-xL and Mcl-1), Bcl-2 effector proteins, (Bak and Bax), direct activator BH3-only proteins (Bid, Bim and Puma) and sensitizer/derepressor proteins (Bad, Bik, Bmf, Hrk and Noxa) Complex ... coordinate cell death and cell proliferation and guarantee tissue homeostasisand normal development Dysfunction of apoptosis is associated with severe human pathologies such as cancer and neurodegenerative ... transport chain and ATP production levels, interrupts reserve metabolism (glycogen and trehalose metabolism and glucan synthesis), and regulates the central carbon metabolism and amino acid biosynthesis...
... Cell Metabolism – Cell Homeostasisand Stress Response Kühlbrandt W Biology, structure and mechanism of p-type ATPases Nature 2004; 5:282295 Kustermans G, Piette J & Legrand-Poels S Actin-targeting ... (morphology and size) and route of intake 2.1 Chemical form Uranium is a heavy metal that forms compounds and complexes of different varieties and solubilities The chemical action of all isotopes and ... toxicity 116 Cell Metabolism – Cell Homeostasisand Stress Response Uranium in the environment, routes of entrance to the body and impact on health Uranium is a natural and commonly occurring radioactive...
... fetal serum (Gibco, Grand Island, NY, USA), with 100 IU/mL penicillin, 100g/mL streptomycin and 2mmol/L glutamine (Gibco, Grand Island) in an humidified incubator with 5% CO2 and 95% air at 37oC ... accumulative destructive effects and there is no interaction between current chemo- and radiotherapy protocols and PDT The most common 152 Cell Metabolism Cell Homeostasisand Stress Response disadvantages ... apparently involve both caspase dependent and independence apoptotic pathways Specifically in head and neck cancer, PDT seems to active caspase-8 and caspase-9 pathway and their upstream NFkB-JNK pathways...
... Peng, Wang and Shan, 2009 sFRP(s) colon cancer, mesothelioma, bladder cancer Tan and Kelsey, 2009; Paul and Dey, 2008; Gehrke, Gandhirajan and Kreuzer, 2009 GSK-3β colorectal cancer Ge and Wang, ... 2009; Yanaga and Sasaguri, 2007) 184 Cell Metabolism – Cell Homeostasisand Stress Response Moreover, the betweenness centrality and bridging centrality (nodes between modules and connecting ... SFN SMAD3 178 Cell Metabolism – Cell Homeostasisand Stress Response LRSAM1 (leucine rich repeat and sterile alpha motif containing1), also called RIFLE and TAL (TSG101-associated ligase), is...
... Paul S and Dey, A., 2008, “Wnt Signaling and Cancer Development: Therapeutic Implication”, Neoplasma, Vol 55, pp 165-176 188 Cell Metabolism – Cell Homeostasisand Stress Response Peifer,M and ... and Tandem Mass Spectrometry”, Molecular and Cellular Proteomics, Vol 7, pp 1162-1173 Saneyoshi, T., Kume, S., Amasaki, Y., and Mikoshiba, K., 2002, “The Wnt/calcium pathway activates NF-AT and ... signaling in oncogenesis and embryogenesis-a look outside the nucleus”, Science, Vol 287,1606-1609 Peng, Z., Wang, H and Shan, C., 2009, “Expression of ubiquitin and cullin-1 and its clinicopathological...
... the study by Yudoh and colleagues and previous reports by us and other groups strongly support the notion that HIF-1 is of pivotal importance in cartilage development andhomeostasis Furthermore, ... Using RNA-interference, Yudoh and colleagues [1] further analyzed the role of HIF-1 in chondrocytic energy generation, matrix synthesis and cell survival During hypoxic and normoxic conditions, functional ... cell-mediated inflammation Cell 2003, 112:645-657 Pfander D, Cramer T, Swoboda B: Hypoxia and HIF-1alpha in osteoarthritis Int Orthop 2005, 29:6-9 Pfander D, Kortje D, Zimmermann R, Weseloh G, Kirsch...
... Innovation through Science and Technology in Flanders (IWT Vlaanderen), the Research Foundation Flanders (FWO Vlaanderen) (grant G.0390.03), a GOA grant from KU Leuven, and a Bristol-Meyers Squibb ... ligands in synovium and cartilage during collagen-induced arthritis arthritis Relative expression of BMP subfamily members BMP2 and BMP4 (green), BMP6 and BMP7 (red), GDF5 (dashed blue), and ... bone morphogenetic protein ligands in collagen-induced arthritis – mRNA level Quantitative PCR for different BMP ligands and BMP antagonist NOG in both synovium and cartilage extracts (three...
... delivery, with a one- and five-minute Apgar score of andand normal birth weight The infant was a first child, and the parents, of east European descent, were non-consanguineous and reportedly healthy ... viral respiratory infections, at the age of four and seven months, and was treated with poractant alpha, dexamethasone, iNO and ventilation for four and nine days respectively At seven months, a ... was normal Brain MRI showed an ectopic and hypoplastic pituitary gland, partial optical nerve atrophy, and bilateral occipital white matter injury Thyroid gland ultrasonography was unremarkable...
... parents Rasma and Raimonds, my brother Edmunds, his wife Dina, and my grandparents Emilija, Katrina and Leokadija Each of you has contributed to my growth at different times through my life and your ... GI tract 16 Posttranslational protein modifications andcontractility 19 Inflammation andcontractility 20 Thesis and Rationale 21 Chapter II: Hprt-targeted transgenes ... first joined the lab, Dr Min Zhang and Dr Jiliang Zhou for your help and advice, Meng Chen, Dr Jury Kim and Rebekah Jones for your contributions to my work and your friendship I would also like...
... cell polarization, and the interactions between PAKs and proteins catalyzing sterol synthesis and storage, it is tempting to speculate that Ste20p and Cla4p may influence sterol homeostasis In this ... Ste20p and Cla4p may inhibit sterol biosynthesis Notably, we observed (using TLC and GLC ⁄ MS) higher amounts of sterols in the ste20D and the cla4D strains TLC separates free sterols and SE, and ... Erg4p, Cbr1p and Ncp1p, which are all involved in sterol biosynthesis [25] We also observed genetic interactions between PAKs and ERG4 as well as between PAKs and NCP1 Both ERG4 and NCP1 are...
... microenvironment and affect neurons only second hand Therefore, understanding the elements of the neuronal environment and the interactions with neurons, and with each other, is crucial in understanding ... Freeman and Håkan Widner,1998 Gene Therapy for Neurological Disorders and Brain Tumors, edited by E Antonio Chiocca and Xandra O Breakefield, 1998 Highly Selective Neurotoxins: Basic and Clinical ... oxide, adenosine, potassium, and pH (30–35) Finally, vascular (endothelial cells and vascular smooth muscle) and parenchymal (neurons and glia) cells cooperate closely, and directly influence each...
... simulations and experimental data for cell density (dotted line and open squares, respectively), glucose concentration (broken line and open circles) and ethanol concentration (full line and filled ... choline- and ethanolamine-free medium in both experiments and simulations, no net synthesis of the major yeast phospholipids, PE and PC, via the Kennedy pathway was observable Adding choline and ethanolamine ... PC and PE by this route, which might be favored because of its lower energy demand The additional possibility for PE and PC synthesis further stimulated TAG mobilization to satisfy the demand...
... CuZnSOD and MnSOD in q+ and q0 cells from osteosarcoma (bone), rhabdomyosarcoma (muscle) and lung carcinoma (lung) mRNA values of CuZnSOD and MnSOD are normalized for ribosomal 36B4 gene and are ... markers of cytosolic and mitochondria-enriched fractions, lactate dehydrogenase (LDH) [29] and citrate synthase (CS) [30] activities were assayed in total cells and in cytosolic and mitochondria-enriched ... 0.1 mM NADPH, and % 300 lg protein The specific activity was calculated by using an extinction molar coefficient obtained by a standard curve of NADPH between 0.02 and 0.1 lmolesÆmL)1 and GR activity...
... causes defects in energy homeostasisand accumulation of damaged proteins and organelles, which is deleterious for survival Excessive autophagy causes too much degradation and tissue malfunction, ... autophagy and causes the death of worms during starvation, and that excessive autophagy causes defects in the pharyngeal muscles and eventually contributes to Fine-tuning of autophagy in C elegans homeostasis ... Bcl-2-dependent inhibition and thereby activate autophagy, (e) extracellular signal-regulated kinase, which phosphorylates and activates Ga interacting proteins and stimulates autophagy and (f) the eukaryotic...