greater differentiation potential of adult stem cells ý pdf

Báo cáo y học: "Comparative transcriptome analysis of embryonic and adult stem cells with extended and limited differentiation capacity" pps

Ngày tải lên : 14/08/2014, 08:20

... developmental path to neural fate by global expression profiling of mouse embryonic stem cells and adult neural stem/ progenitor cells Stem Cells 2006, 24:889-895 NIA array analysis [http://lgsun.grc.nia.nih.gov/ANOVA/ ... Background Multiple types of adult stem cell exist, of which the hematopoietic stem cell (HSC), which gives rise to cells of all hematopoietic lineages for the life of an animal, is the best ... candidate regulators of MAPC self-renewal that will need to be validated using functional studies to elucidate their role in self-renewal and differentiation potential of adult stem cells transcription...

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Báo cáo toán học: "Adult neurogenesis, neuroinflammation and therapeutic potential of adult neural stem cells" ppsx

Ngày tải lên : 08/08/2014, 17:20

... neuronal cells in the adult brain originate from residual stem cells The existence of stem cells in the adult brain suggests that it has the potential for self-repair and that newborn neuronal cells ... stimulation of endogenous neural progenitor or stem cells and the transplantation of adult- derived neural progenitor and stem cells [39] Self-renewing multipotent neural progenitor and stem cells have ... plasticity of the nervous system Adult- derived neural progenitor and stem cells grafted in the brain promote neuroprotection, by an immunomodulatory mechanism Grafted neural progenitor and stem cells...

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Báo cáo y học: "Microenvironmental changes during differentiation of mesenchymal stem cells towards chondrocytes" ppt

Ngày tải lên : 09/08/2014, 10:20

... chondrogenic differentiation of mesenchymal stem cells (MSCs) The gene-expression (MSCs) profile of mesenchymal stem cells (MSCs; n = 2) was analysed by real-time PCR during their differentiation towards ... Figure Time-course expression of chemokines and their receptors during chondrogenic differentiation of mesenchymal stem cells (MSCs) The gene(MSCs) expression profile of MSCs (n = 2) was analysed ... metalloproteinases in the differentiation and biological 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 characterization of mesenchymal stem cells Stem Cells 2006, 24:475-481 Charo IF, Ransohoff RM: The...

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Báo cáo y học: " Curcumin mediated suppression of nuclear factor-κB promotes chondrogenic differentiation of mesenchymal stem cells in a high-density co-culture microenvironment" pdf

Ngày tải lên : 12/08/2014, 14:22

... Characterisation of canine adipose tissue derived mesenchymal stem cells In order to demonstrate that the cells isolated from the canine adipose tissue (Figure 1A) are indeed mesenchymal stem cells (MSCs) ... effects of curcumin inhibit the induction of degradative and inflammatory pathways by IL-1β through revoking activation of caspase-3, production of COX-2, phosphorylation of Iκ-Bα and inhibition of ... inhibits chondrogenic differentiation of MSCs in OA and the effect of curcumin Trauma, inflammation or a combination of both (1) lead to the production and accumulation of high levels of pro-inflammatory...

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differentiation of embryonic stem cells

Ngày tải lên : 11/04/2014, 00:32

... Section I Differentiation of Mouse Embryonic Stem Cells [1] Lineage Specific Differentiation of Mouse ES Cells: Formation and Differentiation of Early Primitive Ectoderm-like (EPL) Cells By JOY ... TABLE OF CONTENTS Development of Hematopoietic Repopulating Cells from Embryonic Stem Cells The In Vitro Diﬀerentiation of Mouse Embryonic Stem Cells into Neutrophils 10 Development and Analysis of ... Murine Embryonic Stem Cells 11 Development of Lymphoid Lineages Embryonic Stem Cells In Vitro from 12 Probing Dendritic Cell Function by Guiding the Diﬀerentiation of Embryonic Stem Cells 13 Gene...

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Báo cáo khoa học: "In vitro neuronal and osteogenic differentiation of mesenchymal stem cells from human umbilical cord blood" ppt

Ngày tải lên : 07/08/2014, 18:21

... tnecseroulf gniwollof ehT SBP htiw semit eerht desnir erew selpmas ehT Co73 ta h rof sllec eht htiw detabucni erew seidobitna yramirp ehT ylevitcepser ,PAFG rof 002 : dna ESN rof 002 : ta ares ... 001-X notirT %4.0 neht dna ,nim rof enoteca %001 ,nim 01 rof lonahtem %001 dloc eci htiw detaert neht erew yehT erutarepmet moor ta nim 01 rof SBP ni edyhedlamrof %7.3 htiw dexif neht dna SBP ... llec gnimrofrep dna esu lacinilc rof SBF gnisu tuohtiw oviv xe sCSM dnapxe ot sdohtem dnif ot deen ew dna ,hcraeser ruo rof SBF desu ew ,yduts tneserp ni ,revewoH noitarefilorp sCSM rof noitidnoc...

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Báo cáo y học: "An in vitro study investigating the survival and phenotype of mesenchymal stem cells following injection into nucleus pulposus tissue" pot

Ngày tải lên : 09/08/2014, 01:22

... accelerated degeneration of the treated IVD [18-24] An alternative cell source are adult stem cells, in particular, bone-marrow-derived mesenchymal stem cells (MSCs) The use of these cells would allow ... Induction of intervertebral disc-like cells from adult mesenchymal stem cells Stem Cells 2005, 23:403-411 44 Risbud MV, Albert TJ, Guttapalli A, Vresilovic EJ, Hillibrand AS, Vaccaro AR, Shapiro IM: Differentiation ... mesenchymal stem cell differentiation Stem Cells 2006, 24:707-716 27 Richardson SM, Hughes N, Hunt JA, Freemont AJ, Hoyland JA: Human mesenchymal stem cell differentiation to NP-like cells in chitosan-glycerophosphate...

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Báo cáo y học: "Proliferation and differentiation potential of chondrocytes from osteoarthritic patients" ppt

Ngày tải lên : 09/08/2014, 06:22

... observed in the average number of cells per milligram of cartilage between the affected and unaffected sides (Table 1) These numbers did not differ from the average number of cells isolated from ACT ... increase in the size of pellets from day to day 14 The histological sections of these pellets showed flattened cells on the surface and round cells in the centre (Fig 3) Spindle-shaped cells were found ... be detected throughout the whole thickness of the scaffold, but higher concentrations of cells were observed on the side of the scaffold from which the cells had been seeded (Fig 5) This cell distribution...

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Báo cáo y học: "Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute" potx

Ngày tải lên : 09/08/2014, 08:23

... mesenchymal stem cells and neural progenitor cells Haematologica 2003, 88:126-133 Reyes M, Verfaillie CM: Characterization of multipotent adult progenitor cells, a subpopulation of mesenchymal stem cells ... L-selectin)/lymphohematopoietic stem and progenitor cells, small-vessel endothelial cells, embryonic fibroblasts Augments B responses/ plasma cells Growth, differentiation, and isotype-switching of B cells/ B cells Ligand ... infused in the 32nd week of pregnancy After an uneventful pregnancy a bone biopsy performed at months of age demonstrated engraftment of Y chromosome positive cells (7.4% of total cells) [52] These...

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Báo cáo y học: "Chondrogenic differentiation potential of osteoarthritic chondrocytes and their possible use in matrix-associated autologous chondrocyte transplantation" pot

Ngày tải lên : 09/08/2014, 14:22

... chondrogenic potential of OA chondrocytes The expression pattern of genes identified during ND chondrocyte differentiation was analyzed in cells obtained from patients with OA Eighty five of the 107 ... uniform distribution of the cells and prevention of cells escaping into the articular cavity Another advantage is the potential for treating larger defects [8] This is of special importance for ... replacement of the implant with newly formed tissue and also support re -differentiation of the chondrocytes [3,5-7] Advantages of this second-generation technique include a more uniform distribution of...

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Báo cáo y học: "Obstructive apneas induce early activation of mesenchymal stem cells and enhancement of endothelial wound healing" ppsx

Ngày tải lên : 12/08/2014, 11:22

... repair of vascular endothelium [6,7] Only a very few studies, however, have focused on the potential role of stem cells in OSA, although there have been recent reports of the detection of circulating ... dividing the number of Page of cells counted by the mean value of counted cells in controls Endothelial wound healing assay A wound healing assay was used to investigate the effects of apneic serum ... early activation of MSC: specifically, an increase in the mobility of these stem cells and in their adhesion to endothelial cells Moreover, it was also found that the serum of apneic rats improved...

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Báo cáo y học: " Influence of hypoxia on the domiciliation of Mesenchymal Stem Cells after infusion into rats: possibilities of targeting pulmonary artery remodeling via cells therapies " doc

Ngày tải lên : 12/08/2014, 18:20

... Mesenchymal stem cells used during this study Mesenchymal stem cells used during this study Typical morphological aspects of mesenchymal stem cells observed through culture flask (A) Mesenchymal stem cells ... perspective of cellular therapy by intravenous stem cells infusion The participation of stem cells in several vascular diseases pathogenesis was first proved with haematopoietic stem cells (HSCs) ... distribution of mesenchymal stem cells in vivo Figure Early dynamic distribution of mesenchymal stem cells in vivo Sequential whole body scintigraphies after infusion of indium-111 labeled mesenchymal stem...

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Báo cáo y học: "Population genetics of cancer cell clones: possible implications of cancer stem cells" pptx

Ngày tải lên : 13/08/2014, 16:20

... by comparison of the relative strength of selection with non -stem cells could furthermore provide a method of testing the relative strength of selection of stem cells and non -stem cells and thereby ... representing a tumour of a given size The number of stem cells is calculated by assuming one stem cell per 57 000 non -stem cells [28] A greater proportion of stem cells would result in a less dramatic difference ... can see that for any size of tumour, because of the much smaller number of stem cells, clonal evolution is predicted to be faster in stem cells compared to non -stem cells What are the mechanisms...

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Báo cáo y học: "Identification and isolation of embryonic stem cells in reproductive endocrinology: theoretical protocols for conservation of human embryos derived from in vitro fertilization" ppsx

Ngày tải lên : 13/08/2014, 23:20

... Refinement and increased efficiency of these two ESC protocols brings the potential to offer a reliable supply of embryonic stem cells without production of whole embryos or compromising extant ... scoring system Stem cell research: social and political factors Public sharing of information about the basic science of ESCs has proven to be important, since those who are aware of the stem cell ... ESC production could proceed with much greater likelihood given the uniformity of all sampled cells Given the unknown extent of embryo mosaicism, limitations of single blastomere biopsy have been...

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Báo cáo khoa học: Epigenetics: the study of embryonic stem cells by restriction landmark genomic scanning pptx

Ngày tải lên : 23/03/2014, 07:20

... study of embryonic stem cells TE N Hattori and K Shiota ICM PGC TS cells Placental cells 77 ES cells 49 EG cells Embryonic cells Fig Epigenetic distances between ES cells and other stem cells ... methylation proﬁles Epigenetic study of embryonic stem cells Differences in DNA methylation proﬁles between ES and other stem cells Comparing ES cells with other stem cells established from developing ... establishment of embryonic stem (ES) cells, which maintain the ability to form all types of cells in the body, and can differentiate into a variety of cell types in vitro [8] The use of ES cells in...

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báo cáo hóa học:" Implantation of neural stem cells embedded in hyaluronic acid and collagen composite conduit promotes regeneration in a rabbit facial nerve injury model" doc

Ngày tải lên : 18/06/2014, 15:20

... immunohistochemical staining of BrdU and S-100 Representative images of immunohistochemical staining of BrdU and S-100 A: Localization of darkly brownish stained BrdU+ cells to transected tissues of rabbits having ... 7042014 of the National Science Foundation of Beijing, China, the 50573044 of the National Natural Science Foundation of China and the 2005CB623905 of the National Basic Research Program of China ... protruding processes Immunofluorescence staining of β-tubulin, GFAP and GalC demonstrated positive expressions in a substantial number of cells, suggesting that neurosphere-derived cells were able to...

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Báo cáo hóa học: "Future research and therapeutic applications of human stem cells: general, regulatory, and bioethical aspects" ppt

Ngày tải lên : 18/06/2014, 16:20

... Induced pluripotent stem cells Induced pluripotent stem cells (iPSCs) from somatic cells are revolutionizing the field of stem cells Obtained by reprogramming somatic stem cells of a patient through ... here lies in implantation of hepatic stem cells, or in implantation of hepatic cells obtained by differentiation of a different type of stem cell, such as mesenchymal stem cells Other applications, ... are at least, if not more capable than those from adult (stem) cells Mesenchymal stem cells Although adult stem cells are primarily unipotent cells, under certain conditions they show a plasticity...

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báo cáo hóa học:" Targeting of mesenchymal stem cells to ovarian tumors via an artificial receptor" docx

Ngày tải lên : 20/06/2014, 07:20

... the level of cells that home to tumors or other sites The tumor homing behavior of MSCs was demonstrated by the mere presence of these cells in the sites of interest and/or lack of such cells in ... phenomenon of MSCs was confirmed in different experimental systems [2,12] Other cell types, such as umbilical cord matrix stem cells (UCMS) [14], neural stem cells [15,16] and endothelial progenitor cells ... delivery of CX3CL1 to multiple lung tumors by mesenchymal stem cells Stem Cells 2007, 25(7):1618-26 12 Komarova S, Kawakami Y, Stoff-Khalili MA, Curiel DT, Pereboeva L: Mesenchymal progenitor cells...

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The signals of FGFs on the neurogenesis of embryonic stem cells ppsx

Ngày tải lên : 10/08/2014, 05:21

... detect the Sox1-GFP+ cells from day to day (Fig 3A) The number of Sox1+ cells became 20% of total cells on day and reached the plateau, 50% of total cells, on day Treatment of FGF1 consistently ... promotes self-renewal of mouse embryonic stem cells Dev Biol 1999, 210:30-43 Li Z, Theus MH, Wei L: Role of ERK 1/2 signaling in neuronal differentiation of cultured embryonic stem cells Dev Growth ... cannot shorten the time of the neural induction from ES cells The Sox1-GFP+ cells did not appear on differentiation day 2, regardless of the FGF1 treatment The increase of Sox1+ cells in the FGF1-treated...

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báo cáo khoa học: " The HPB-AML-I cell line possesses the properties of mesenchymal stem cells" ppt

Ngày tải lên : 10/08/2014, 10:20

... Regulation of stemness and stem cell niche of mesenchymal stem cells: implications in tumorigenesis and metastasis J Cell Physiol 2010, 222:268-277 Ohishi M, Schipani E: Bone marrow mesenchymal stem cells ... mesenchymal stem cells Oncol Rep 2004, 12:501-508 22 Lee HJ, Choi BH, Min BH, Park SR: Changes in surface markers of human mesenchymal stem cells during the chondrogenic differentiation and dedifferentiation ... undifferentiated cells Inverted microscopic examination demonstrated the presence of a number of vacuoles in the cytoplasm of differentiated HPB-AML-I cells (Figure 4G) In contrast to the undifferentiated cells...

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