... R, et al Post-traumatic glioma: Report of two cases Tumori 2006; 92:175-7 Preston-Martin S, Pogoda JM, Schlehofer B, et al An international case-control study of adult glioma and meningioma: the ... Henry PT, Rajshekhar V: Post-traumatic malignant glioma: case report and review of the literature Br J Neurosurgery 2000; 14:64-7 Manuelidis EH Glioma in trauma In: Minckler J, ed Pathology of ... Scerrati M, et al Post traumatic malignant glioma Report of a case Ital J Neurol Sci 1996; 17:283-286 Hu XW, Zhang YH, Wang JJ, et al Angiocentric glioma with rich blood supply J Clin Neurosci...
... resistance by approaches designed to reactivate apoptosis in malignant glioma has important implications for the development of novel glioma therapies Tumor necrosis factor-related apoptosis-inducing ... irradiation To analyze the sensitivity of high-grade gliomas to cell death induced by the death ligand TRAIL, we employed a panel of six grade III–IV glioma cell lines (U87, U251, U343, U373, MZ-18, ... [14,15] PIs potently reactivate TRAIL-induced apoptosis in glioma cells Next, we investigated the synergistic effects of TRAIL and PIs in our glioma cell lines For that purpose, we employed two different...
... ras-activated factor/extracellularly regulated kinase (Raf/ERK) pathway and the activation of the p38 MAPK/SAPK2 pathway Independently of these pathways, protein kinase C (PKC) is able to phosphorylate ... the regulatory signal transduction pathways involved in this activation While no evidence for activation of the p38MAPK/SAPK2 pathway exist from our data, other pathways involving ERK1/2 and potentially ... whereas the Raf/ERK pathway is preferentially activated upon binding of growth factors to receptor tyrosine kinases ([18] and many others) While there is some overlap of both pathways our data...
... Concepts in Targeting Glioma, Edited by Faris Farassati p cm ISBN 978-953-51-0491-9 Contents Preface IX Part Chapter Part Surgical Therapy of Glioma Innovative Surgical Management of Glioma Dave Seecharan, ... Blood-Brain Barrier in Glioma Therapy 109 Blood-Brain Barrier and Effectiveness of Therapy Against Brain Tumors 111 Yadollah Omidi and Jaleh Barar Gene Therapy of Glioma 141 Chapter Glioma- Parvovirus ... in Glioma 199 Manas R Biswal, Howard M Prentice and Janet C Blanks LGI1 in Treatment of Glioma 217 The Tumor Suppressor Function of LGI1 219 Nadia Gabellini Antioxidant Adaptive Response in Glioma...
... astrocytes (Fig 4A) Similarly, the changes in glioma C6 cell A Astrocytes B Fig GFAP expression in serum-deprived glioma C6 cells Total protein isolated from glioma cells was subjected to SDS ⁄ PAGE ... malignant gliomas J Neurosurg 95, 480–488 Vajkoczy P, Goldbrunner R, Farhadi M, Vince G, Schilling L, Tonn JC, Schmiedek P & Menger MD (1999) Glioma cell migration is associated with gliomainduced ... in glioma C6 cells Br J Pharmacol 132, 393–402 Baranska J, Czajkowski R & Sabala P (2004) Crosstalks between nucleotide receptor-induced signaling pathways in serum-deprived and non-starved glioma...
... Gd-G8 accumulate in glioma cells Rhodamine B GdG2 dendrimers enter RG-2 glioma cells, and in some cases, the nucleus (left) Rhodamine B Gd-G5 dendrimers enter the cytoplasm of RG-2 glioma cells, but ... effective drug delivery vehicles across the BBTB of malignant gliomas By performing intravital fluorescence microscopy of xenografted human glioma microvasculature in the mouse cranial window model, ... traversing the BBTB of malignant gliomas is the large size of these particles relative to the physiologic pore size of the BBTB In this work, using the RG-2 malignant glioma model [38,39], we also...
... transduction pathways, are emerging for glioma treatment However, the outcome of this kind of treatment is strictly dependent upon the gene expression/protein activation profile of each malignant glioma ... normal brain and human glioma samples, helped to draft the manuscript LB: collected human normal brain and human glioma samples RG: collected human normal brain and human glioma samples VG: participated ... of unselected patients suggesting that the inhibition of a specific pathway may result in the activation of a compensatory pathway that allows the tumour to survive For these reasons novel therapeutic...
... displaying p-STAT-3 compared to glioma expression Pathology % of PBMCs displaying p-STAT-3 % of glioma cells displaying nuclear p-STAT-3 Ganglioglioma 10.6 ± 87 Ganglioglioma 0.2 ± 33 Recurrent AA ... in the glioma To determine if the level of p-STAT-3 positive cells in the glioma correlated to the mean percent of PBMCs displaying p-STAT-3, we performed a subgroup analysis in which glioma ... enhanced in PBMCs from glioma Expression of p-STAT-3 is enhanced in PBMCs from glioma patients PBMCs were isolated from blood samples obtained from healthy donors (N = 19) and glioma patients (N...
... Materials and methods 2.1 Tumor cell lines Human cerebral glioma cell line (BMG-1; DNA index = 0.95; wild-type p53), established from a mixed glioma [14] was used in the present studies Monolayer ... a high power (1000 W) Xenon arc lamp (Oriel, USA), using an optical filter (cut off at 610 nm) with the petridishes placed on ice Optical power at the cell surface was measured using radiometer ... human glioma and squamous carcinoma cell lines J Photochem Photobiol B 2003, 69:107-120 Dwarkanath BS, Jain VK: Energy linked modifications of the radiation response in a human cerebral glioma...
... Concepts in Targeting Glioma, Edited by Faris Farassati p cm ISBN 978-953-51-0491-9 Contents Preface IX Part Chapter Part Surgical Therapy of Glioma Innovative Surgical Management of Glioma Dave Seecharan, ... Blood-Brain Barrier in Glioma Therapy 109 Blood-Brain Barrier and Effectiveness of Therapy Against Brain Tumors 111 Yadollah Omidi and Jaleh Barar Gene Therapy of Glioma 141 Chapter Glioma- Parvovirus ... in Glioma 199 Manas R Biswal, Howard M Prentice and Janet C Blanks LGI1 in Treatment of Glioma 217 The Tumor Suppressor Function of LGI1 219 Nadia Gabellini Antioxidant Adaptive Response in Glioma...
... biomarkers in glioma Following six chapters under section “Gliomagenesis” deals with different genetic, molecular and cell biological aspects of origin and development of glioma The next section Glioma ... Protein in Gliomagenesis 131 Ivana Magnani, Chiara Novielli and Lidia Larizza Chapter New Insight on the Role of Transient Receptor Potential (TRP) Channels in Driven Gliomagenesis Pathways 163 ... and Elena Chernykh Contents Part Glioma Model and Culture Systems 343 Chapter 16 Animal Models of Glioma Lijun Sun Chapter 17 Three-Dimensional In Vitro Models in Glioma Research - Focus on Spheroids...
... Ficarra G, Callari G, Sola P, Merelli E: Monofocal acute large demyelinating lesion mimicking brain glioma Neurol Sci 2004, 25: S386-388 20 Engelter ST, Rueegg S, Kirsch EC, Fluri F, Probst A, Steck ... Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literature World Journal of Surgical Oncology 2011 9:97...
... such directly related cultures, we examined the radioresponse of stem-like glioma cells (SLGCs) and of more differentiated glioma cells in terms of cell death mechanisms, focusing on both apoptosis ... Comparative analysis of DNA repair in stem and nonstem glioma cell cultures Mol Cancer Res 2009, 7(3):383-392 20 Frosina G: DNA repair and resistance of gliomas to chemotherapy and radiotherapy Mol Cancer ... in glioma Int J Cancer 2011, 128(3):501-510 25 Wang J, Sakariassen PO, Tsinkalovsky O, Immervoll H, Boe SO, Svendsen A, Prestegarden L, Rosland G, Thorsen F, Stuhr L, et al: CD133 negative glioma...
... conditions in the radioresistant glioma U251MG and U343MG cell lines Methods Cell culture conditions, treatments with BA and irradiation The human malignant glioma cell lines U251MG and U343MG ... EGFR/AKT pathway and the expression of survivin contributed to a lower sensitivity in response to BA treatment in human melanoma cells [29] In the present study, the increased cytotoxicity in both glioma ... radiosensitivity in both human glioma cell lines [38], in addition to HT1080 human fibrosarcoma cells [40,41] The downregulation of HIF-1a consistently increased the sensitivity of human glioma cells to doxorubicin...
... Sublethal photon irradiation enhances glioma cell migration Since photon irradiation is implemented in most glioma treatment protocols, we irradiated U87 glioma cells with single photon doses ... analysis of integrins was performed in U87 and Ln229 glioma cells following RT Statistical analysis was performed using Student’s t-test Results: Glioma cell migration is serum-dependent and can ... antibodies inhibits Vn-based migration of both untreated and photonirradiated glioma cells Conclusions: Peripheral glioma cells are at risk of attraction into the adjacent healthy brain by serum...
... postoperative FET-PET imaging for the RT planning of high-grade glioma The inclusion criteria for the trial were: 1) the diagnosis of high-grade glioma; 2) residual tumor on MRI performed ≤ 24 hours postoperatively; ... FET in glioma volume delineation for RT planning Although inter-observer variability has been assessed for tumor definition with other amino-acids, no such analysis has been taken in glioma delineation ... Biopsy 10(52) Subtotal removal 8(42) Gross total removal 0(0) None* 1(5.5) Histology Glioma, grade WHO IV* 14(74) Glioma, grade WHO III 5(26) MiB1 (%) n = 16 Median 15 Range – 50 Magnetic resonance...
... but not the TOMO plan (p > 0.5) spared the optic chiasm significantly better then the IMRT plan All plans met the pre defined dose constrains for the optic chiasm Patients' characteristics A total ... radiotherapy for high-grade gliomas: Does IMRT increase the integral dose to normal brain? IJROBP 2007, 67(4):1135-44 Fiveash JB, Nordal JM, Markert RS, Ahmed RS, Nabors LB: High Grade Gliomas In Clinical ... outside the skull were trimmed with 0.5 cm inner margin to the body contour The globes and the optic chiasm were contoured and were designated as organs at risk during the treatment planning...
... Figure Conventional MR imaging, Target volume and Dosimetry of a Low-grade Glioma A left thalamic low-grade oligodendroglioma in a 10 year-old boy after partial resection, without contrast enhancement ... pseudoprogression in malignant gliomas Lancet Oncol 2008, 9:453-461 Lafay-cousin L, Feniak J, Wilson B, Wei X, Rotaru C, Bouffet E, Strother D: Pseudoprogression in pediatric diffuse pontine glioma treated with ... histopathology and localized DSC perfusion MR imaging measurements in a series of adult high-grade gliomas [11] Consequently, we favoured the hypothesis of a delayed radiation injury and began a...