genetics and nutrigenomics of obesity
kumar - molecular genetics and breeding of forest trees (haworth, 2004)
... molecular genetics such as functional genomics, ESTs, and SSRs, and the profound case studies addressing temperate and tropical trees.” Prof Dr Reiner Finkeldey Chair of Forest Genetics and Forest ... Highlights of the book include a description of the EST databases of Genesis Research and Development Corporation, Ltd., in New Zealand; an excellent review of the state of knowledge of lignin ... quality and productivity of forests, which has been spread through a diverse array of journals and periodicals in need of consolidation for educational and reference material Molecular Genetics and...
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the genetics and biology of sex determination - novartis foundation
... Zarkower Department of Genetics, Cell Biology and Development, University of Minnesota, 6-160 Jackson Hall, 321 Church Street, SE, Minneapolis, MN 55455, USA The Genetics and Biology of Sex Determination: ... Chadwick and Jamie Goode Copyright Novartis Foundation 2002 ISBN: 0-470-84346-2 An introduction to the genetics and biology of sex determination Roger V Short Department of Obstetrics and Gynaecology, ... expression of other genes, such as Amh, and led to the repression of Sry and Dax1 The di¡erentiating Sertoli cells also produce signals responsible for the migration of peritubular myoid and endothelial...
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GENETICS AND ETIOLOGY OF DOWN SYNDROME pdf
... after QFQ-staining are diagnosed in 2.0 % of band p11.2 and 10.0 % of band p13 Duplications in p12 show a frequency of 0.7-1.3 % and 0.1 % in the satellites of p13 Deletions in all three regions ... order of size and of the position of the centromere According to the type of induced banding pattern, two subtypes can be defined: a) those resulting in bands distributed along the length of the ... heterochromatic but consists of different types of repetitive DNA (Figure 1)(Wyandt and Tonk, 2004) The relative length of the short arm of chromosome 21 comprises 30 % of its total length (Figure...
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GENETICS AND PATHOPHYSIOLOGY OF ESSENTIAL HYPERTENSION doc
... pathophysiology, genetics and genomics of hypertension This book is divided into two main sections: Pathophysiology, and Genetics and Genomics In pathophysiology, topics such as pathophysiology of resistant ... mitochondrial mutations and pharmacogenetics of hypertension A chapter on microarray technology details the technique and identifies expression of altered genes Role of TGF-β and other inflammatory ... the incidence of ischemic disease of the heart, heart failure, brain attack, and the incidence of lethal attacks It is necessary to understand the regulation of blood pressure and especially...
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Chapter 075. Evaluation and Management of Obesity (Part 1) ppt
... weight status and risk of disease (Tables 75-1 and 75-2) BMI is used since it provides an estimate of body fat and is related to risk of disease Lower BMI thresholds for overweight and obesity have ... Classification of Weight Status and Risk of Disease BMI (kg/m2) Obesity Class Risk of Disease Underweight
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Chapter 075. Evaluation and Management of Obesity (Part 2) potx
... as a treatment approach Obesity- Associated Comorbid Conditions The evaluation of comorbid conditions should be based on presentation of symptoms, risk factors, and index of suspicion All patients ... indirectly related to obesity are listed in Table 75-4 Although individuals vary, the number and severity of organspecific comorbid conditions usually rise with increasing levels of obesity Patients ... fasting lipid panel (total, LDL, and HDL cholesterol and triglyceride levels) and blood glucose measured at presentation along with blood pressure determination Symptoms and diseases that are directly...
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Chapter 075. Evaluation and Management of Obesity (Part 3) pptx
... change and also serves as a basis for further dialogue Obesity: Treatment The Goal of Therapy The primary goal of treatment is to improve obesity- related comorbid conditions and reduce the risk of ... Lung, and Blood Institute: Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: The evidence report Washington, DC, US Department of Health and ... initial weight-loss goal of 10% over months is a realistic target Figure 75-1 Treatment algorithm This algorithm applies only to the assessment for overweight and obesity and subsequent decisions...
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Chapter 075. Evaluation and Management of Obesity (Part 4) pptx
... fruits and vegetables, consuming more whole-grain cereals, selecting leaner cuts of meat and skimmed dairy products, reducing fried foods and other added fats and oils, and drinking water instead of ... day; limiting cholesterol to
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Chapter 075. Evaluation and Management of Obesity (Part 5) pot
... discontinuation of the medication A dose of 10–15 mg/d causes an average increase in systolic and diastolic blood pressure of 2–4 mmHg and an increase in heart rate of 4–6 beats/min For this reason, ... used to help change and reinforce new dietary and physical activity behaviors Strategies include self-monitoring techniques (e.g., journaling, weighing, and measuring food and activity); stress ... >27 kg/m2 who also have concomitant obesityrelated diseases and for whom dietary and physical activity therapy has not been successful When prescribing an antiobesity medication, patients should...
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Chapter 075. Evaluation and Management of Obesity (Part 6) docx
... receptors and their endogenous ligands have been implicated in a variety of physiologic functions, including feeding, modulation of pain, emotional behavior, and peripheral lipid metabolism Cannabis and ... Restrictive surgeries limit the amount of food the stomach can hold and slow the rate of gastric emptying The vertical banded gastroplasty (VBG) is the prototype of this category but is currently ... the drug is related to the malabsorption of dietary fat and subsequent passage of fat in the feces GI tract adverse effects are reported in at least 10% of orlistat-treated patients These include...
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Chapter 075. Evaluation and Management of Obesity (Part 7) ppsx
... National Heart, Lung, and Blood Institute, North American Association for the Study of Obesity: Practical guide: Identification, evaluation, and treatment of overweight and obesity in adults Bethesda, ... systematic review and meta-analysis of randomized controlled trials Int J Obesity 27:1437, 2003 [PMID: 12975638] Wadden TA et al: Lifestyle modification for the management of obesity Gastroenterology ... Roadmaps for clinical practice: Case studies in disease prevention and health promotion—assessment and management of adult obesity: A primer for physicians Chicago, American Medical Association,...
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Báo cáo y học: " Advances in the genetics and epigenetics of gene regulation and human disease" pps
... generations of offspring He and his colleagues postulate that maternal nutrition before and during pregnancy may affect the establishment of CpG methylation and the life-long expression of metastable ... analysis of genes that are involved in cell-cycle control and cell-size regulation in Drosophila Using flow cytometry, Björklund and colleagues analyzed the RNAi-induced loss -of- function of 70% of ... specificities and the assembly of their binding sites to form tissuespecific enhancer elements is critical for understanding key regulatory mechanisms of human gene expression Outi Hallikas (University of...
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Tài liệu The Practical Guide: Identification, Evaluation, and Treatment of Overweight and Obesity in Adults pdf
... Problem of Overweight and Obesity .5 Treatment Guidelines Assessment and Classification of Overweight and Obesity Assessment of Risk Status 11 Evaluation and ... Study of Obesity (NAASO) and the National Heart, Lung, and Blood Institute (NHLBI) It is based on the Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity ... physicians can and should engage the assistance of other professionals This guide provides the basic tools needed to assess and manage overweight and obesity for a variety of health professionals,...
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Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx
... user of long-chain fatty acids making a brain-specific isoform intriguing CPT1c was identified and cloned from in silico sequences as a highly homologous member of the CPT1 class of enzymes and ... carbohydrate and lipid nutrient sensing in the brain and is an example of an enzyme that can sense and respond to the nutritional environment The major challenge to understanding the role of CPT1c ... mediators in the treatment of obesity M J Wolfgang and M D Lane One of the biggest challenges to the field is the lack of experimental tools to investigate intermediary metabolites and lipids in general...
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Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx
... inflammation of adipose tissue in obesity and related insulin resistance [15] Here, we focus on the roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obesity and related metabolic diseases, and discuss whether these ... Induction Fig Schematic diagram showing the roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obesity and related metabolic diseases The expression of ANGPTL2 and ANGPTL6 ⁄ AGF is induced in obese conditions ... inflammation and systemic insulin resistance through the induction of vascular inflammation and monocyte migration ANGPTL6 ⁄ AGF antagonizes obesity and insulin resistance through the enhancement of systemic...
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Tài liệu Báo cáo khoa học: Mechanisms of obesity and related pathologies: Androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction pptx
... dysfunction and ED [130,131], the concept of androgen deficiency reinforces the important role of androgens in vascular health and erectile function Summary and conclusions Visceral obesity, in ... the link between obesity and ED by focusing on the potential pathophysiological links including obesity- related androgen deficiency and obesity- induced endothelial dysfunction Obesity promotes ... and hypogonadism-induced obesity remain the subject of intense investigation Several hypotheses have discussed the relationship of androgen deficiency and obesity That obesity is commonly associated...
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Tài liệu Obesity guidance on the prevention, identification, assessment and management of overweight and obesity in adults and children ppt
... management of overweight and obesity in the NHS, and advice on the prevention of overweight and obesity that applies in both NHS and nonNHS settings The guidance supports the implementation of the ... However, the age and maturity of the child and the preferences of the child and the parents should be taken into account 1.2.2 Identification and classification of overweight and obesity 1.2.2.1 ... prevention and management of obesity should be a priority for all, because of the considerable health benefits of maintaining a healthy weight and the health risks associated with overweight and obesity...
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Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc
... development and subsequent clinical course of some types of obesity In this minireview, we focus on adipocyte hyperplasia as a novel therapeutic target for the treatment of obesity and discuss ... clinical use of this approach in obesity therapy RMI1 and obesity Using a random mutagenesis approach based on the exchangeable gene trap method, we recently identified RMI1 as a novel regulator of energy ... present, and therefore more detailed understanding of adipocyte hyperplasia in humans is essential for the development of efficacious and safe treatments As emphasized here, RMI1 is one of the most...
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The challenge of obesity in the WHO European Region and the strategies for response pptx
... presence of a mental disorder, has been associated with poor treatment outcome of 34 • THE CHALLENGE OF OBESITY obesity (20); health and mental health professionals should be aware of this and screen ... advertisers and traders – to revise its policies, both voluntarily and as a result of legislation Professional organizations need to support the prevention and management of obesity and its associated ... between 30% and 80% of adults in the WHO European Region and up to one third of children The rates of obesity are rising in virtually all parts of the Region The costs to the health services of treating...
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