... during diastole. Since both, a reduced myocar-dial perfusion reserve and diastolic heart failure, are an integral part of systolic heartfailure any abnormal shortening of diastolic time, ... of LV diastolic time is a common characteristic of heart failure patients which can be explained by the high prevalence of mechanical dyssynchrony. Key words: diastolic time, heart failure, ... limited to pa-tients with advanced heartfailure and NYHA III func-tional class and may therefore not be readily gener-alizable to patients with a milder or a more severer degree of heart failure. ...
... employed historically to relate the experimental data to strength quantities used for static design, are presented. Subsequent tutorials, Static Failure of Ductile Materials and Static Failure ... required to characterize the material behavior of a brittle material, Sut and Suc. SUMMARY This tutorial has attempted to provide a focused introduction to the development of static failure ... TUTORIAL 6, PART A: INTRODUCTION TO STATIC FAILURE THEORIES APPROACH Theories have been developed for the static failure of metals based upon the two classes of material failure; ...
... contraindicatedin patients with heartfailure and normal systolicfunction. However, the ACC/AHA Guidelines [18]recommend digoxin to minimize symptoms of heart failure in patients with diastolic dysfunctionas ... approachand many heartfailure specialists believe that thethiazide diuretics have too little potency in a heart failure population. When patients have moderate to severe heartfailure symptoms or renal ... stable heart failures symptoms. Similarly, Grinstead et al. [16]evaluated 41 patients with stable, but symptomatic heart failure. After discontinuing diuretic therapy,patients were randomized to...
... CHRONIC HEARTFAILURE 18MANAGEMENT OF CHRONIC HEARTFAILURE 1++1+In patients with heartfailure and sinus rhythm, digoxin may reduce symptoms and hospital admission for worsening heartfailure ... sleep apnea and heartfailure trialCHARM Candesartan in Heart failure: Assessment of Reduction in Mortality trialCHD coronary heart diseaseCHF chronic heart failure CHSS Chest Heart and Stroke ... debrillators are relevant toheartfailure but they are dealt with fully in SIGN guideline 94 on cardiac arrhythmias in coronary heart disease.1This guideline refers only to chronic heart failure...
... accumulation during latespermatogenesis appears to be detrimental to the germ cellsand, hence, antizyme 3 apparently functions to limit anyODC expression to the early spermatogenesis. The trans-gene-derived ... ternarycomplex with the transcription factor Smad1 and protea-somal subunit HsN3 that is translocated into nucleus inresponse to bone morphogenetic protein receptor activation[22]. In the nucleus, ... ratprostate carcinoma cells [127]. The failure of spermine to inhibit the latter cells is believed to be attributable to theinability of the polyamine to induce antizyme in the highlymetastatic...
... to Pluto, the probe will reach a top speed of about 70,000 kilometers per hour.■ The craft’s computers will be able to store 48 gigabits of data and transmit the information to Earth at up to ... chemicals that enable cells to re-spond to inflammatory mediators.Experimental drugs that aim at oth-er risk factors for heart disease and strokemight exert useful anti-inflammatory ef-fects as well. ... farms and factories, were foundby the first national stream survey designed to look for “contaminants of emerging con-cern”—tough -to- measure, relative newcom-ers to pollution monitoring.Most...