... helpful to study the evolution ofthevirus with its point mutations, because the incidence of recombination is rare and any point mutation could effect thegeneticcharacteristicsof two overlapped ... Thecharacteristicsofthe synonymous codon usage in hepatitis B virus and the effects of host on thevirus in codon usage pattern Ming-ren Ma, Xiao-qin ... 1) Figure Thegenetic characteristic of HBV isolated different countries Based on the subtypes of HBV, the plots for the subtype adw were generally divided into two groups, while the other three...
... Page of 11 countries ofthe Far East such as Mongolia (2000) and Russia (2000) [3,11,33] The extent to thegenetic diversity of these PanAsia virus isolates accumulating over the course of FMD ... attenuation of these viruses Y79 H within bC strand and E136G within E-F loop of VP2, T142N/A and A152T within G-H loop of VP1 are exposed on the surface ofthe viral capsid The direct induction of capsid ... experiments and the finding of molecular basis for the derivation ofgenetic mutants by utilizing reverse genetics These studies may help us to clarify how is it that the mutations responsible for genetic...
... numbers of DENV sequences in the GenBank has given a better picture ofthegenetic diversity of these viruses, suggesting the existence of intragenotipic groups within each genotype Identification of ... diversity and the phylogenetic relationship ofthe viruses To analyze the diversity ofthe E protein, nucleotide sequences were aligned and compared Any ofthe 1479 sites in the alignment were considered ... analysis ofthe topology ofthe phylogenetic tree suggests the existence of intragenotipic groups (Figure 1) To better characterize these internal groups, protein E gene sequences of members of each...
... region showing the position ofthe Predicted stem-loop secondary structure ofthe STLVPredicted stem-loop secondary structure ofthe STLV-3d(Cmo8699AB) LTR region showing the position ofthe Rex responsive ... a similar loss of biologic activity The effects of these changes on the processing of viral transcripts and regulation of viral replication by the STLV-3d Rex will require further investigation ... well-established genetic and archaeological evidence for the timing of migration ofthe ancestors of indigenous Melanesians and Australians from Southeast Asia [14,16,29,41] The PTLV evolutionary...
... Given that the roles of these residues definitely confirm each other, the difference in their significance might be attributable to the importance and ⁄ or necessity ofthe receipt ofthe phenol-hydroxyl ... rationale for the major role of Arg316 in arresting the ligand When the amino acid sequences ofthe LBD of all the NRs were aligned to that of ERRc, it became noticeable that 26 receptors among the total ... ligand-binding pocket ofthe ERRc The proximity of each amino acid residue (within a ˚ distance of A) to BPA is shown in the boxes depicting the a-helices The portrait was originated from the X-ray crystal...
... Fragments of HSQC and HMBC spectra of compound Labels illustrate assignment ofthe amide linkage between the amino group of Asp and the carboxyl group of GalA residue E Scheme The structures of oligosaccharides ... branching information [31] The charge state of a fragment ion is then identified by using the isotope profile, owing to the high resolution provided by the TOF mass analyser The product-ion spectrum ... 1436.42, owing to the loss ofthe branching xylose residues M and O, and of GlcA residue L The remaining linear sequence, consisting of K-B-F-I-D-N-Q, was confirmed by the observation of Ó FEBS 2004...
... Characteristicsofthe Voi Mep massif’s altitudinal belt differentiation 11 Topographic features ofthe Voi Mep massif Voi Mep massif with the highest peak (1739m) ofthe same name ... narrow water divide surfaces On the background of an old weathering crust also emerge granitic blocks of different sizes, rather well eroded, creating a peculiarity ofthe top surface Currently this ... process - Slopes on granites: there are many steep slopes on the west ofthe massive, developed along fissures, tectonic faults cutting into granites The origin of these surfaces are rapid gravity...
... together, these data confirm the specificity ofthe SenR-binding sites and corroborate the assumption that phosphorylation of SenR by SenSP alters its DNA-binding characteristics Discussion The ... released with the same solution in the presence of 250 mm imidazole The protein concentration ofthe samples was determined by a previously established method [42] The quality ofthe proteins ... addition of 12 pmol of SenR to the reaction mixture led to an 84% decrease of free up-furS1, whereas the same amount of SenRP provoked only a 10% reduction (Fig 5D) The presence of small...
... eliminate the possibility ofthe functional roles ofthe )643T>C and )1219G>A SNPs as part ofthe extended APOH promoter transcriptional machinery To further substantiate the functional relevance ofthe ... conjunction with the luciferase gene in pGL3basic vector The nucleotides are numbered from the translation start site The effect ofthe wild-type and mutants was measured as the mean ofthe firefly luciferase ... purpose, we tested 12 ofthe 14 sequence variants located within the 1418 bp ofthe 5¢ flanking region of APOH for allele-specific regulatory effects on the expression ofthe dual luciferase reporter...
... making the management ofthe disease easier Median value of PCI of family ofthe patients was Rs 400 and mean value was Rs 543 with a range of Rs 100 - 2500 The mean PCI of family ofthe patients ... depicts the reproductive characteristics mean of 48.1 years Ten out of 27 ovarian cancer cases ofthe patients Nearly two-third ofthe patients with (37.1%) were found between the ages of 35 and ... two-third ofthe monthly income (PCI) of family ofthe patients, which patients (78 out of 113 patients or 69.0%) were in the was Rs 400, the patients with gynecological malignancies age range of 35-64...
... membrane of many, if not all, mammalian cells [16-20] Among these peptides, the PTD ofthe Tat protein (PTDtat) of human immunodeficiency viruses types and (HIV-1 and HIV-2) has been one ofthe most ... modification strategy We genetically incorporated the sequences encoding the PTDtat peptide into the 3' end ofthe Ad5 fiber gene, rescued the modified viruses, and characterized them in detail Our ... hours) following addition ofthe viruses to the cells by immunofluorescent staining, and found that the distribution of Ad5.PTDtat inside the cells was similar to that of unmodified Ad5 vectors...
... dependent on virus infectivity Later and systemically, thevirus protects the host from any fatal consequences ofthe suppression ofthe immune system by compensatory enhanced activities of splenic ... participated in the design ofthe study, carried out the work with the mice, assisted in experimental work and drafting ofthe manuscript Abdel-Moneim conceived the study, designed and carried out the experimental ... Bergle RD, Thein P: The effectiveness ofthe paramunity inducer Baypamun (PIND-ORF) for the prevention and metaphylaxis of an experimental infection with the infectious bovine rhinotracheitis virus...
... The serum samples from ofthe IgM negative cases were taken days after rash onset when the sensitivity of IgM detection is low Comparison ofthe N gene sequences ofthe Turkish viruses with the ... fact, the N gene sequences of 21 of these MV isolates were identical, though they came from different regions of Turkey Although the Turkish viruses were clearly in genotype D6, the sequences ofthe ... Phylogenetic analysis ofthe N gene sequences of wild-type MVs isolated in Turkey Phylogenetic analysis ofthe N gene sequences of wild-type MVs isolated in Turkey Sequences ofthe Turkish viruses...
... Multiple alignment ofthe complete env sequences of representative prototypes ofthe SRV-2 subtypes Multiple alignment ofthe complete env sequences of representative prototypes ofthe SRV-2 subtypes ... analysis ofthe SRV-2 sequences revealed the presence of six separate clusters of sequences (Figure 1B) These clusters represent six molecular subtypes of SRV-2 The subtype SRV-2A cluster included the ... related virus, MmMich, obtained in the late1990's from a rhesus macaque at the primate center at the University of Michigan (see Table for a description of viruses and their macaque hosts) The SRV-2B...
... resulting in the shut off of host protein synthesis On the other hand, the function of L ofthe cardioviruses is not well defined L has been implicated in other functions of picornaviruses FMDV ... picornaviruses The aphthoviruses and caridioviruses are the only members ofthe Picornaviridae family that contains an L coding region at the most 5' terminus ofthe ORF [13] In the case of foot-and-mouth ... viral spread L of mengovirus, which also belongs to the genus Cardiovirus, has been reported to inhibit the iron/ferritinmediated activation of NFκB [34] The functions of L of Page of (page number...