genes and posttranslational modifications

Genes and the social environment

... complex interactions between genes and the social environment Understanding their implications and the new biology they describe are key goals for the behavioural sciences and for psychiatry Devising ... children and the effect of genotype was assessed on 14 measures of cognitive function, including working memory, verbal and motor inhibition, attentional control, and IQ, assessed at ages and 10 ... interactions in schizophrenia and other disorders One serious issue in these studies will be the specificity of the genetic and environmental risks The search for candidate genes for schizophrenia...

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Tài liệu CANCER, GENES AND INHERITED PREDISPOSITION OvERvIEw – Cancer Genetics pptx

Danh mục: Sức khỏe giới tính

... CANCER, GENES AND INHERITED PREDISPOSITION Overview – Cancer Genetics ‘Cancer protection’ genes Since the growth control genes normally provide information to prevent ... much accelerator) • Mismatch repair genes • These are genes that are involved in finding and repairing mistakes in the genetic information that can occur when the genes are copied to make new cells ... to make the car move (the accelerator or oncogenes) and stop (the brakes or tumour suppressor genes) must be in balance Also the mismatch repair genes are like the mechanic who keeps the car...

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Pleasure and Its Modifications: Witasek, Meinong and the Aesthetics of the Grazer Schule potx

Danh mục: Mỹ thuật

... colour, shadow and sound, and of the Gestalten of formal, typical and expressive beauty founded thereon, and apprehend also what they signify or represent But represented states of affairs and the like ... empirischen Standpunkt, 2nd ed., with introduction and notes by O Kraus, Leipzig: Meiner; Eng trans Psychology from and Empirical Standpoint, by L.L.McAlister et al., London: Routledge and Kegan ... moment which a judgment and an assumption may have in common and in virtue of which they are then directed towards one and the same state of affairs The distinction between act and content now gives...

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Genes and chromosomes the genome

Danh mục: Sinh học

... plan is packaged in the cells in the form of genes Chromosomes can be thought of as being made up of strings of genes The chromosomes, and therefore the genes, are made up of the chemical substance ... genetic information Thousands of genes make up each chromosome Since the chromosomes come in pairs, there are two copies of the genes The exception to this rule applies to the genes carried on the ... chromosomes: the X and Y Figure 1.6: Picture of chromosomes from a male as seen under a microscope and arranged in order of size (SEALS Genetics Prince of Wales Hospital, Randwick) As we age and grow,...

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Genes and Autoimmunity - Intracellular Signaling and Microbiome Contribution by Spaska Angelova Stanilova pot

Danh mục: Sức khỏe giới tính

... TPOAb levels [61] 4.7 Cytokine genes, immune related genes and others According to recent advances in the understanding of immune cell subsets and cytokines, several genes encoding different inflammatory ... receptors and TLR-associated genes have recently attracted great interest as candidate genes for autoim‐ mune diseases Over the past decade there has been great interest in testing candidate gene ... patients and GD with GO patients 5.1 The pathogenesis of GO GO is an orbital manifestation of AITDs, mainly GD, and develops in 25-50% of GD patents and up to 5% of HT patients The pathogenesis...

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Báo cáo khoa học: Identiﬁcation of rice TUBBY-like genes and their evolution Qingpo Liu docx

Danh mục: Báo cáo khoa học

... 11 and 12 By contrast with only one OsTLP found on chromosomes 3, 4, 7, 8, 11 and 12, three (OsTLP5, OsTLP9 and OsTLP12), two (OsTLP8 and OsTLP13) and three (OsTLP1, OsTLP10 and OsTLP11) genes ... within the ﬁfth (E5, site 103) and ninth (E9A, site 312; E9B, site 319) b-strands, and the loop between E9A and E9B (sites 315 and 317) (supplementary Fig S1) TUBBY-like genes in rice Santagata et ... pairs (OsTLP6 ⁄ and OsTLP7 ⁄ 14) may be the result of recent segmental duplication of chromosomes 11 and 12 and chromosomes and 7, respectively [13,14] With regard to OsTLP8 and OsTLP13, they...

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GENES AND AUTOIMMUNITY - INTRACELLULAR SIGNALING AND MICROBIOME CONTRIBUTION docx

Danh mục: Cao đẳng - Đại học

... TPOAb levels [61] 4.7 Cytokine genes, immune related genes and others According to recent advances in the understanding of immune cell subsets and cytokines, several genes encoding different inflammatory ... receptors and TLR-associated genes have recently attracted great interest as candidate genes for autoim‐ mune diseases Over the past decade there has been great interest in testing candidate gene ... patients and GD with GO patients 5.1 The pathogenesis of GO GO is an orbital manifestation of AITDs, mainly GD, and develops in 25-50% of GD patents and up to 5% of HT patients The pathogenesis...

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reece - analysis of genes and genomes (wiley, 2004)

Danh mục: Sinh học

... Analysis of Genes and Genomes Richard J Reece University of Manchester, UK John Wiley & Sons, Ltd Analysis of Genes and Genomes Analysis of Genes and Genomes Richard J Reece University ... extension mutagenesis 7.2 Strand selection methods 7.2.1 Phosphorothioate strand selection 7.2.2 dut− ung− (or Kunkel) strand selection 7.3 Cassette mutagenesis 7.4 PCR based mutagenesis 7.5 QuikChange ... helix Base pairing (A to T and G to C) holds the two strands of the helix together DNA replication occurs through the unwinding of the DNA strands and copying each strand The central dogma of molecular...

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applications of chimeric genes and hybrid proteins, part a

Danh mục: Sinh học

... using hybrid genes and proteins to identify and analyze protein-protein and protein-nucleic interactions, for mapping molecular recognition domains, for directed molecular evolution, and for functional ... the rlI genes of the Escherichia coli bacteriophage T4 In the late 1950s and early 1960s, Seymour Benzer and colleagues charactered two adjacent but independently transcribed genes, rlIA and rlIB, ... site and therefore carries a 3' fragment comprising roughly one-third of the lacZ gene, as well as functional lacy and lacA genes phages and differences in the analysis of transcriptional and...

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applications of chimeric genes and hybrid proteins, part b

Danh mục: Sinh học

... cognate ligands or receptors in tissues or cells In [15] in this volume4 we describe other applications: molecular characterization of ligands and receptors, and the cloning of novel ligands and receptors ... Fritze and T Anderson, Biotechniques, in preparation J W Jarvik and C A Telmer, Annu Rev Genet 32,601 (1998) Y Shiio, M Itoh, and J Inoue, Methods Enzymol 254, 497 (1995) P A Kolodziej and R A ... of Cells, Tissues, and Embryos By JOHN G FLANAGAN, MITSUHARU HATTORI, HWAI-JONG CHENG, DAVID A FELDHEIM, QIANG Lu, and PIERRE VANDERHAEGHEN Introduction Polypeptide ligands and their cell surface...

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posttranslational modifications of proteins

Danh mục: Sinh học

... protein modifications, on the one hand, and the development and availability of sophisticated, sensitive analytical methods on the other hand, are already leading to increased interest in co- and posttranslational ... in their ability to carry out posttranslational modifications and that changes in cell culture conditions also influence these modifications Thus, posttranslational modifications of recombinant ... Bing-Yuan Chen and Harry W Janes, 2002 191 Telomeres and Telomerase: Methods and Protocols, edited by John A Double and Michael J Thompson, 2002 190 High Throughput Screening: Methods and Protocols,...

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geopolitics and the green revolution wheat genes and the cold war dec 1997

Danh mục: Vật lý

... in the years after 1940: England, Mexico, the United States, and India In England (Figure 2.4) and India (Figure 2.5), wheat came several thousands of years ago and has been cultivated every ... on the basis of maize and other seed crops in the Tehuacan valley in Mexico and from root crops such as manioc, sweet potato, achira, and potato in the lowland and highland areas of what is now ... survival and into the wealth and power central to human societies Plant Breeding and Yields An inquiry into agriculture from the political ecological viewpoint focuses on how and why people modify and...

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Báo cáo hóa học: " Multiplexed methylation profiles of tumor suppressor genes and clinical outcome in lung cancer" potx

Danh mục: Hóa học - Dầu khí

... clinical and laboratory data, data analysis and interpretation, and drafted the manuscript PP and LG participated in acquiring clinical and laboratory data, data analysis and data interpretation and ... DJ: Aberrant CpG-island methylation has non-random and tumour-type-specific patterns Nat Genet 2000, 24(2):132-8 Esteller M: CpG island hypermethylation and tumor suppressor genes: A booming present, ... manuscript LG, JV, and SQ participated in acquiring clinical samples and follow-up clinical information MSC participated in study design and coordination, data analysis and interpretation and final writing...

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Báo cáo sinh học: " Progressive loss of CD3 expression after HTLV-I infection results from chromatin remodeling affecting all the CD3 genes and persists despite early viral genes silencing" pot

Danh mục: Hóa học - Dầu khí

... using the endogenous genes (EF-1-α and MLN51) as a normalizer and uninfected WE17/10 cells as a calibrator The individual CD3 genes were normalized to the endogenous controls and the values are ... decrease is followed by a subsequent progressive and sequential reduction in CD3δ, CD3ε and CD3ζ genes transcription, going on after early viral genes silencing Our experiments also demonstrate ... CD3γ/CD3δ gene region The human CD3γ, CD3δ and CD3ε genes are located in a 50 kb cluster on chromosome 11q23, with CD3γ and CD3δ positioned head-to-head and separated by 1.6 kb DNase I hypersensitivity...

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Báo cáo hóa học: " Progressive loss of CD3 expression after HTLV-I infection results from chromatin remodeling affecting all the CD3 genes and persists despite early viral genes silencing" docx

Danh mục: Hóa học - Dầu khí

... using the endogenous genes (EF-1-α and MLN51) as a normalizer and uninfected WE17/10 cells as a calibrator The individual CD3 genes were normalized to the endogenous controls and the values are ... decrease is followed by a subsequent progressive and sequential reduction in CD3δ, CD3ε and CD3ζ genes transcription, going on after early viral genes silencing Our experiments also demonstrate ... CD3γ/CD3δ gene region The human CD3γ, CD3δ and CD3ε genes are located in a 50 kb cluster on chromosome 11q23, with CD3γ and CD3δ positioned head-to-head and separated by 1.6 kb DNase I hypersensitivity...

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Báo cáo hóa học: " Measuring and analyzing tissue specificity of human genes and protein complexes" potx

Danh mục: Hóa học - Dầu khí

... Measuring and analyzing tissue specificity of human genes and protein complexes EURASIP Journal on Bioinformatics and Systems Biology 2011 2011:5 Submit your manuscript to a journal and beneﬁt ... with a maximum of 0.61 in liver and a minimum of 0.44 in testis The average correlation between the Gene Atlas and RNA-sequencing data is 0.27 and between Gene Atlas and Exon Array data 0.28 The ... tissue-specific genes are detected in skeletal muscle and the highest in testis We also compared the actual genes found to be expressed according to the different methods We observed a high agreement of genes...

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Báo cáo y học: "Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis" ppsx

Danh mục: Báo cáo khoa học

... specificity and structural relationships of the natural substrates trichohyalin and filaggrin J Biol Chem 1996, 271: 30709-30716 Utz PJ, Gensler TJ, Anderson P: Death, autoantigen modifications, and ... plasma cells and constitute a higher proportion of IgG than in synovial fluid and serum Clin Exp Immunol 2000, 119:544-552 Klareskog L, Lorentzen J, Padyukov L, Alfredsson L: Genes and environment ... their charge and their structure [4,14] Many known autoantigens become modified during cell death and, in particular, during apoptosis (for an overview see [15]) B Correlation between RA and certain...

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Báo cáo y học: "4th meeting of the EU research network EUROME: From the identification of genes and cellular networks in murine models of arthritis to novel therapeutic intervention strategies in rheumatoid arthritis, London, UK, 9 March 2004" pot

Danh mục: Báo cáo khoa học

... Arthritis Research & Therapy Vol No Ibrahim and Paleolog as lymph nodes and joints at various stages of disease in susceptible DBA/1J and resistant FVB/N strains In parallel, a genome screen ... and 13, one for CD4/CD8 ratio on chromosome 2, and one for cell proliferation on chromosome 16 The group also described the first example of an epistatic interaction involving mitochondrial and ... identify the genes controlling this disease the group has made crosses between susceptible and resistant rat strains Several loci that control the onset of arthritis, the severity and chronicity...

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Báo cáo y học: "Regulatory polymorphisms in extracellular matrix protease genes and susceptibility to rheumatoid arthritis: a case-control study" ppsx

Danh mục: Báo cáo khoa học

... protease genes (MMP7, MMP1, MMP3 and MMP13) are in a MMP cluster that covers 500 kb in chromosome 11q and includes at least another five MMPencoding genes Therefore, we checked if they were in LD and ... the two SNPs in MMP7 (-181 A/G and -153 C/T), between the MMP1 -1607 1G/2G and MMP3 -1171 6A/5A SNPs, and between MMP13 -77 A/G and two other SNPs (MMP3 -1171 6A/5A and MMP7 -153 C/T) Comparison ... linked to local and systemic activation of coagulation and fibrinolysis pathways J Thromb Haemost 2003, 1:2510-2515 28 Saxne T, Lecander I, Geborek P: Plasminogen activators and plasminogen activator...

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Báo cáo y học: "HLA-DRB1 genes and extraarticular rheumatoid arthritis" potx

Danh mục: Báo cáo khoa học

... patients from the US, Europe and Asia [5] In this metaanalysis, three double dose genotypes were found associated with vasculitis, namely DRB1*0401/0401, DRB1*0401/0404 and DRB1*0401/0101 [5] Conclusion ... a similar study, comparing cohorts of patients with extraarticular RA and purely articular RA, in a population where DR4 and DR1 are more equally represented This could be the subject of a very ... Turesson C, Schaid DJ, Weyand CM, Jacobsson LTH, Goronzy JJ, Petersson IF, Sturfelt G, Nyhäll-Wåhlin BM, Truedsson L, Dechant SA, Matteson EL: The impact of HLA-DRB1 genes on extraarticular disease...

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