general features hepatitis a hepatitis e and other viruses

Báo cáo sinh học: " Hepatitis C (HCV), hepatitis B (HBV), the human immunodeficiency viruses (HIV), and other viruses that replicate via RNA intermediaries," pdf

Ngày tải lên : 18/06/2014, 22:20

... hypothesis Viral polymerases are clearly the effector mechanism – the efferent arm – that determines rate of viral RNA replication and mutation The afferent arm needs to measure both the rate of ... have overlapping open reading frames and significant alterations in envelope and polymerase gene and protein sequences cannot, therefore, occur independently, a genetic nexus again implying an ... untenable explanation of this massive apparent fall in immune clearance pressures; if occurred to any degree, an increase, rather than the observed decrease, in viremia would result In the absence...

14
329
0

Báo cáo y học: "Sustained eradication of hepatitis C virus by low-dose long-term interferon therapy in a renal transplant recipient with dual infection with hepatitis B and C viruses: a case report" pptx

Ngày tải lên : 10/08/2014, 23:21

... patient’s serum HCV RNA was successfully eradicated after three and onehalf years of antiviral therapy without any episodes of allograft rejection Case presentation A 51-year-old Taiwanese man ... mild elevated aminotransferase levels about one to threefold the upper limit of normal were noted Prednisolone was withdrawn at the same time Marked elevation of aminotransferase levels (up to sevenfold ... rejection After the end of treatment, the patient’s ALT levels were still mildly elevated Since both his HBV DNA and HCV RNA were negative, it was likely that fatty liver rather than viral hepatitis...

4
282
0

Tài liệu Define a Primary Key and Other Indexes docx

Ngày tải lên : 14/12/2013, 20:16

... create tables, you create your primary key columns and indexes at the same time You can come up with indexes at a later date as well Comments Be sure to create a primary key column for each of ... field per table 4 To create other indexes that will help performance, choose Indexes/Keys from the View menu to open the Property Pages dialog box On the Indexes page, click the New button, and ... tables, and use identity columns for primary columns whenever possible SQL Server will take advantage of indexes you have created, but just be careful not to over-index Remember to examine what...

5
383
0

Báo cáo khoa học: Halogenated benzimidazoles and benzotriazoles as inhibitors of the NTPase/helicase activities of hepatitis C and related viruses ppt

Ngày tải lên : 08/03/2014, 02:20

... micromolar range We herein describe the inhibitory properties of TBBT, and a number of related benzotriazoles and benzimidazoles, at the NTPase/helicase sites of HCV and the related viruses Japanese ... radioactivity associated with the released strand and with the nonunwound substrate quantiﬁed with GELIMAGE software (Amersham Pharmacia Biotech) Assays were carried out with the same level of enzyme activity, ... with the enzymes, some action at the level of the RNA and/ or DNA substrates cannot be unequivocally excluded Various benzimidazole analogues have been demonstrated to intercalate into dsRNA and/ or...

9
659
0

WHO Guidelines for Pharmacological Management of Pandemic Influenza A(H1N1) 2009 and other Influenza Viruses potx

Ngày tải lên : 08/03/2014, 14:20

... (in particular those less than 2 years of age). Other Treatment Considerations: There are generally fewer data available on the safety and efficacy of antiviral medicines in very ... higher dosing) is needed in obese patients. Pregnancy and breastfeeding Treatment recommendations for pregnancy and breastfeeding are covered by recommendations 01‐05 and 09‐18 and there are ... virus, as well as more recent observational data and experience in the clinical management of pandemic (H1N1) 2009 influenza. It is anticipated that as the prevalence and severity of the current epidemic changes, further information will ...

32
439
0

Báo cáo khoa học: "An efﬁcient algorithm for building a distributional thesaurus (and other Sketch Engine developments)" pdf

Ngày tải lên : 31/03/2014, 01:20

... (summing where we have multiple instances of the same w1 , w2 as we proceed) and output the sorted stream Then we merge sorted streams, again summing as we proceed Another technique we use is partitioning ... speed were made at substantial cost to accuracy Here, data from these highfrequency contexts makes negligible impact on thesaurus entries 1.3 Available thesauruses Thesauruses of the kind described ... how other words of the same word class behave We have implemented histograms like these in the Sketch Engine for a range of word classes and grammatical contexts The histograms are integrated...

4
346
0

Báo cáo y học: "Daily rhythm of circulating fat soluble vitamin concentration (A, D, E and K) in the horse" pdf

Ngày tải lên : 10/08/2014, 09:20

... were expressed as mean ± SD One-way repeated measures analysis of variance (ANOVA) was used to determine significant differences p values < 0.05 were considered statistically significant Data were ... GP-Designed the study and evaluated the data statistically AA-Carried out the data collection procedures FG-Carried out the data collection procedures GC-Supervised the data collection procedures and ... research papers will be: available free of charge to the entire biomedical community peer reviewed and published immediately upon acceptance cited in PubMed and archived on PubMed Central yours...

4
294
0

Báo cáo khoa học: "Gas-permeable ethylene bags for the small scale cultivation of highly pathogenic avian influenza H5N1 and other viruses in embryonated chicken eggs" docx

Ngày tải lên : 12/08/2014, 04:21

... culture plate systems since they have the same problem if dropped; i .e as an added safety feature For larger-scale needs, other primary containment devices could achieve the same goal of increased containment ... viruses, JEV, and VEEV, interpreted data, helped train technicians, and helped draft the manuscript; DED grew influenza viruses, interpreted data, oversaw the training of technicians, and managed ... propagated virus was analyzed by plaque assay and full-genomic sequencing (details to be presented elsewhere) JEV propagation in ECE JEV was inoculated into the YS of - day old ECE, and incubated...

7
383
0

Báo cáo khoa học: "Isolation and characterization of a genotype 4 Hepatitis E virus strain from an infant in China" ppt

Ngày tải lên : 12/08/2014, 04:21

... the other Chinese genotype HEV isolates referenced here, and the highest sequence identity (97.6%) with another Shanghai HEV strain (AB197674) isolated from a Japanese patient who was reportedly ... CD, Bezanilla JC, Toth TE, Meng XJ: Identification of genotype hepatitis E virus (HEV) in serum and faecal samples from pigs in Thailand and Mexico, where genotype and HEV strains are prevalent ... will be: available free of charge to the entire biomedical community peer reviewed and published immediately upon acceptance cited in PubMed and archived on PubMed Central yours — you keep the copyright...

4
311
0

Hepatitis and Liver Cancer: A National Strategy for Prevention and Control of Hepatitis B and C ppt

Ngày tải lên : 06/03/2014, 01:20

... coordinate, and evaluate innovative and effective outreach and education programs to target at-risk populations and to increase awareness in the general population about hepatitis B and hepatitis ... 2, and medical management are both sparse and fragmented among entities at the federal, state, and local levels The committee believes that a coordinated approach is necessary to reduce the numbers ... between acute and chronic hepatitis B and hepatitis C Knowledge and Awareness The committee found that there is relatively poor awareness about hepatitis B and hepatitis C among health-care providers,...

191
457
0

Hepatitis and Liver Cancer: A National Strategy for Prevention and Control of Hepatitis B and C doc

Ngày tải lên : 06/03/2014, 01:20

... related to viral hepatitis prevention, risk-factor screening and serologic testing, and medical management are both sparse and fragmented among entities at the federal, state, and local levels ... with key stakeholders to develop, coordinate, and evaluate innovative and effective outreach and education programs to target at-risk populations and to increase awareness in the general population ... case-management services (for example, testing of household and sexual contacts and referral to medical care) However, most programs are understaffed and underfunded and cannot offer adequate case-management...

253
369
0

Hepatitis and Liver Cancer: A National Strategy for Prevention and Control of Hepatitis B and C pdf

Ngày tải lên : 22/03/2014, 17:20

... chronic hepatitis B and hepatitis C, thousands more Americans will die each year from liver cancer or liver disease related to these preventable diseases f The Centers for Disease Control and Prevention ... rates Therefore, the committee recommends that all states mandate the hepatitis B vaccine series be completed or in progress as a requirement for school attendance Because only about half of at-risk ... Bethesda, Maryland Randall R Mayer Chief, Bureau of HIV, STD, and Hepatitis, Iowa Department of Public Health, Des Moines, Iowa Margaret L Brandeau Professor, Department of Management Science...

4
404
1

Báo cáo khoa học: A structured RNA in hepatitis B virus post-transcriptional regulatory element represses alternative splicing in a sequence-independent and position-dependent manner pot

Ngày tải lên : 28/03/2014, 23:20

... the fragments of the 5¢ end labeled and folded PRE-ISS wild-type RNA, which was cleaved by RNase T1, RNase V1 and RNase A The T1 seq and A seq lanes represent RNase T1 and RNase A sequencing markers, ... Triangles, diamonds and ellipses represent signals for RNase T1, RNase V1 and RNase A, respectively; larger ones represent stronger signals and smaller ones weaker signals (C) Conservation analysis ... stable secondary structures is generally higher than the average of the whole HBV genome sequence, although some fall below the median of the calculated minimal free energy 1542 C Huang et al...

14
379
0

Báo cáo hóa học: " Expression and processing of the Hepatitis E virus ORF1 nonstructural polyprotein" potx

Ngày tải lên : 20/06/2014, 01:20

... the engineered N- and C-terminal tags The predicted methyltransferase (MeT), papain-like cysteine protease (PCP), helicase (Hel) and RNA dependent RNA polymerase (RdRp) domains are shown, as ... these, the MeT and RdRp enzymatic activities have been demonstrated [13,14] while activities of the Hel and PCP have so far not been elucidated Attempts have also been made to study ORF1 processing ... Under the same conditions and at similar times all processed fragments were observed in untreated cells (Fig 3A lanes and respectively), while none of the fragments were seen in cells infected with...

9
249
0

Báo cáo y học: "Human immunodeficiency virus infection and autoimmune hepatitis during highly active anti-retroviral treatment: a case report and review of the literature" potx

Ngày tải lên : 10/08/2014, 23:21

... abdomen was unremarkable She was seen in the office with fever and tachycardia and was hospitalized because of possible sepsis and acute abdomen Her physical examination revealed that she was febrile ... Only three patients developed AIH after starting HAART, similar to our patient The clinical characteristics of the reviewed cases and our case are shown in Table All patients who received HAART prior ... she started to experience gradual right upper quadrant pain associated with intermittent night sweats Her pain increased in intensity and became intractable A computed tomographic scan of her abdomen...

4
407
0

báo cáo khoa học: "Metabolome in schizophrenia and other psychotic disorders: a general population-based study" pptx

Ngày tải lên : 11/08/2014, 12:21

... average values from the measurements Weight was measured during bioimpedance measurement Waist circumference was measured while standing, midway between the lowest rib and the iliac crest, after a ... analysis (Additional file 1) Dependency analysis The linear mixed model analysis suggests that the dependencies of different metabolite classes and related metabolic phenotypes among themselves and ... Finland [19] A twostage stratified cluster sampling procedure was used The field work took place between September 2000 and June 2001, and consisted of a home interview and a health examination at...

14
340
0

Báo cáo y học: "Development and management of systemic lupus erythematosus in an HIV-infected man with hepatitis C and B co-infection following interferon therapy: a case report" doc

Ngày tải lên : 11/08/2014, 17:21

... serum protein electrophoresis and urine Bence Jones proteins were negative A CT scan of the abdomen revealed thickened terminal ileum and moderate ascites Diagnostic paracentesis revealed a Antinuclear ... autoantibodies, and autoimmune diseases needs to be balanced against its benefits The development of autoantibodies and lupus-like features in patients with chronic HCV needed careful assessment and ... immunosuppressants remains unclear, and his viral load remains high In view of his known liver disease and anaemia, we avoided azathioprine and used mycophenolate and prednisolone at small ritonavir-boosted...

5
624
0

báo cáo khoa học: " Prevalence and correlates of HIV, syphilis, and hepatitis B and C infection and harm reduction program use among male injecting drug users in Kabul, Afghanistan: A cross-sectional assessment" ppsx

Ngày tải lên : 11/08/2014, 18:20

... potential associations between outcomes of interest and select demographic and risk behavior variables Variables were entered into a multiple model if they were associated at the 10% level in univariable ... an explosive epidemic Harm reduction program and NSP use appear acceptable and efforts to improve service quality and scale up effective interventions, particularly OST, are urgently needed Abbreviations ... has been noted in other settings, such as the United Kingdom and Canada [23-25] The data indicate that these services are reaching their target clientele; however, service delivery in this setting...

8
374
0

Báo cáo y học: " Dynamics of HEV viremia, fecal shedding and its relationship with transaminases and antibody response in patients with sporadic acute hepatitis E" ppt

Ngày tải lên : 12/08/2014, 01:21

... duration of persistence in days hepatitis E and looked for HEV viremia [11] A study explained 26 patients with acute sporadic hepatitis E, the samples were collected as and when the patient came ... patients was 29.2 ± 8.92 years (range: 11 to 54 years) and there were 39 males and 21 females; there were 10 pregnant and 11 non-pregnant females Five pregnant females were in third trimester, four ... Baseline laboratory markers were expressed as mean values with standard deviation Difference between pregnant and non-pregnant females with respect to various liver function tests, and duration...

7
298
0

Báo cáo y học: "Unexpected elevated alanine aminotransferase, asparte aminotransferase levels and hepatitis E virus infection among persons who work with pigs in accra, ghana" docx

Ngày tải lên : 12/08/2014, 02:20

... are broken and/ or exposed and as such the water may have been easily contaminated with faecal effluent in the locality Moreover, handwashing facilities are not easily available on the farms Another ... urban and rural areas, increased incidence of acute viral hepatitis without a defined aetiology (unpublished data, Department of Medicine and Therapeutics, KBTH), and the high infant and maternal ... of the causative pathogens Several studies [14-17] suggest that elevated serum ALT and AST (> 200 U/L) may be a marker of HEV infection and that individuals with elevated ALT and AST may have ongoing...

9
233
0