general enhancer suppressor or regulator of basal expression
Báo cáo khoa học: Tumor suppressor p16INK4a ) modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells ppt
... direction of expression levels of these two a2,3-sialyltransferase genes for enzymes of similar substrate specificity for N-glycans may act in a compensatory manner, the reduction of gene expression of ... whether the tumor suppressor acts on the expression of the quoted genes directly or indirectly With respect to tumor cells, the case of the differentiation-dependent activation of a cell-surface ... by 25%, mainly as a result of reduced expression of the enzyme b4GalT-I [31] Analysis of transforming growth factor b1-induced rapid senescence of this cell type by northern blots revealed two-...
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Báo cáo khoa học: Myocyte enhancer factor 2 (MEF2) is a key modulator of the expression of the prothoracicotropic hormone gene in the silkworm, Bombyx mori ppt
... promoter enhance expression of the EGFP reporter gene in PTPCs and are important for binding of the BmMEF2 protein Furthermore, overexpression of the BmMEF2 gene can induce PTTH gene expression Thus, ... Identification of cis-regulatory elements controlling PTTH gene expression in brain PTPCs of B mori using AcNPVmediated reporter gene analysis Fluorescence microscopy was used to visualize EGFP expression ... cloning of the Bombyx mori prothoracicotropic hormone Science 247, 1333–1335 Adachi-Yamada T, Iwami M, Kataoka H, Suzuki A & Ishizaki H (1994) Structure and expression of the gene for the prothoracicotropic...
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báo cáo khoa học: " Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1" pps
... standard error of the mean, n = 3) Proliferative activity of VAECs 48 hours post-transfection was assessed by quantification of BrdU incorporation Cells were pulsed for hours and incorporated BrdU ... between high-scoring miRNAs in our screen and those identified by several in vitro microarray studies of HUVECs Many of the miRNAs we identified scored favorably in one or more of these screens, ... presence in pericytes We also performed a functional characterization of miR-145 and could show that it is a regulator of Fli1, and that increased or decreased expression of miR-145 leads to reduced...
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reducing the degree or intensity of, or eliminating, pollution
... transfers money, property, services or anything of value to a state, university, non-profit, or not-for-profit organization for the accomplishment of authorized activities or tasks Th a thu n h p tác: ... di-chloromethane, trichloro-methylene, chloroform công nghi p; Các h p ch t h u ñư c kh b ng clo bao g m dung môi có ch a clo diclorometan, tricloro-metylen, clorofom Chlorinated Solvent: An organic solvent ... Available Chlorine: A measure of the amount of chlorine available in chlorinated lime, hypochlorite compounds, and other materials used as a source of chlorine when compared with that of liquid or gaseous...
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Tài liệu tiếng anh Điện tử công suất mạch MERS A new automatic voltage regulator of self excited induction generator using SVC magnetic energy recovery switch
... current flowing into dc capacitor Larger size of inductor will have better performance to reduce harmonic but it will be more expensive When the size of the dc capacitor of MERS is changed from 110 ... means reducing rms current of the stator at full load condition Therefore by selecting optimal size of dc capacitor and inductor, the harmonic distortion can be reduced for the main operation area ... selection of capacitor and inductor will lead to low distortion for the main operation area Further more, rating reduction of SVC MERS can be achieved with about 60% by combining fixed ac capacitors...
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Analysis of gene expression
... comparison of a standard Northern blot using µg of polyA RNA and a virtual Northern blot using 100 ng of total RNA Virtual Northern blotting has been used successfully for a number of gene expression ... Northern Figure 8.4 Comparison of a standard Northern blot analysis using µg of polyA RNA and a virtual Northern blot using 100 ng of total RNA (Reproduced with permission of CLONTECH Laboratories ... (RNAi) is an important approach for studying the importance of expression of specific genes within cell, tissues or organisms It uses double-stranded RNA to interfere with gene expression and was...
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Tài liệu Minimization or Maximization of Functions part 1 pptx
... minimization sub-algorithm such as Brent’s method (see above) Storage is of order N There are two major families of algorithms for multidimensional minimization with calculation of first derivatives ... minimization sub-algorithm, which can itself either use, or not use, the derivative information, as you see fit (depending on the relative effort of computing the function and of its gradient vector) We not ... require storage of order N and those that require only of order N , where N is the number of dimensions For moderate values of N and reasonable memory sizes this is not a serious constraint There will...
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Tài liệu Minimization or Maximization of Functions part 2 docx
... floating-point precision, a number like × 10−8 (for float) or 10−15 (for double) Not so! In general, the shape of your function f(x) near b will be given by Taylor’s theorem f(x) ≈ f(b) + f (b)(x − b)2 (10.1.1) ... root is a number of order unity Therefore, as√ rule of thumb, it a is hopeless to ask for a bracketing interval of width less than times its central value, a fractional width of only about 10−4 ... prohibited To order Numerical Recipes books,diskettes, or CDROMs visit website http://www.nr.com or call 1-800-872-7423 (North America only) ,or send email to trade@cup.cam.ac.uk (outside North America)...
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Tài liệu Minimization or Maximization of Functions part 3 pdf
... prohibited To order Numerical Recipes books,diskettes, or CDROMs visit website http://www.nr.com or call 1-800-872-7423 (North America only) ,or send email to trade@cup.cam.ac.uk (outside North America) ... the value already evaluated only by an amount of order the roundoff error Therefore in the code below you will find several tests and modifications of a potential new point, imposing this restriction ... prohibited To order Numerical Recipes books,diskettes, or CDROMs visit website http://www.nr.com or call 1-800-872-7423 (North America only) ,or send email to trade@cup.cam.ac.uk (outside North America)...
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Tài liệu Minimization or Maximization of Functions part 4 ppt
... prohibited To order Numerical Recipes books,diskettes, or CDROMs visit website http://www.nr.com or call 1-800-872-7423 (North America only) ,or send email to trade@cup.cam.ac.uk (outside North America) ... school of thought is to “use everything you’ve got”: Compute a polynomial of relatively high order (cubic or above) that agrees with some number of previous function and derivative evaluations For ... are more worried about all the funny “stiff” things that high-order polynomials can (cf Figure 3.0.1b), and about their sensitivities to roundoff error This leads us to use derivative information...
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Tài liệu Minimization or Maximization of Functions part 5 docx
... prohibited To order Numerical Recipes books,diskettes, or CDROMs visit website http://www.nr.com or call 1-800-872-7423 (North America only) ,or send email to trade@cup.cam.ac.uk (outside North America) ... root of the machine precision, it is perfectly appropriate to let ftol be of order the machine precision (or perhaps slightly larger so as not to be diddled by roundoff) Note well that either of ... prohibited To order Numerical Recipes books,diskettes, or CDROMs visit website http://www.nr.com or call 1-800-872-7423 (North America only) ,or send email to trade@cup.cam.ac.uk (outside North America)...
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Tài liệu Minimization or Maximization of Functions part 6 pptx
... [1] for a detailed description and listing of the program Unfortunately it is rather too elaborate for us to include here You can give up the property of quadratic convergence in favor of a more ... subspace of the full N -dimensional case; in other words, it gives the wrong answer Therefore, the algorithm must not be used in the form given above There are a number of ways to fix up the problem of ... minimize a quadratic form Brent [1] gives proofs of these statements in accessible form Unfortunately, there is a problem with Powell’s quadratically convergent algorithm The procedure of throwing away,...
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Tài liệu Foundations of Microsoft Expression Web docx
... reserved No part of this work may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or by any information storage or retrieval ... CHAPTER ■ BEFORE YOU BEGIN Taking Your First Look at Expression Web If you have never used a web editor before but have used Windows or one of the Microsoft Office programs, parts of Expression ... reinforce the topics it explains I recommend working through each of these exercises for hands-on experience Working examples of the completed exercises can be viewed at http://foundationsofexpressionweb.com,...
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Tài liệu Minimization or Maximization of Functions part 7 pptx
... beginner’s error is to assume that any reasonable way of incorporating gradient information should be about as good as any other This line of thought leads to the following not very good algorithm, ... A, nor even the storage necessary to store such a matrix A sequence of directions hi is constructed, using only line minimizations, evaluations of the gradient vector, and an auxiliary vector ... the minimum of the quadratic form But we don’t know A Here is a remarkable theorem to save the day: Suppose we happen to have gi = − f(Pi ), for some point Pi , where f is of the form (10.6.1)...
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Tài liệu Minimization or Maximization of Functions part 8 ppt
... updates the information that is accumulated Instead of requiring intermediate storage on the order of N , the number of dimensions, it requires a matrix of size N × N Generally, for any moderate ... that the updating formula should be of the form Hi+1 = Hi + correction What “objects” are around out of which to construct a correction term? Most notable are the two vectors xi+1 − xi and fi+1 ... implementations of variable metric methods (going beyond the scope of this book, see below) have been developed to a greater level of sophistication on issues like the minimization of roundoff error, handling...
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Tài liệu Minimization or Maximization of Functions part 9 pdf
... constraints, m1 of them of the form ai1 x1 + ai2 x2 + · · · + aiN xN ≤ bi (bi ≥ 0) i = 1, , m1 (10.8.3) m2 of them of the form j = m1 + 1, , m1 + m2 (10.8.4) and m3 of them of the form ak1 x1 ... for a Restricted Normal Form A linear programming problem is said to be in normal form if it has no constraints in the form (10.8.3) or (10.8.4), but rather only equality constraints of the form ... transformed into restricted normal form Therefore bear with us and learn how to apply the simplex method to a restricted normal form Here is an example of a problem in restricted normal form:...
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Tài liệu Minimization or Maximization of Functions part 10 pptx
... very small, of a system being in a high energy state Therefore, there is a corresponding chance for the system to get out of a local energy minimum in favor of finding a better, more global, one ... ((n[3]-n[6]+ncity) % ncity); nn=1; for (j=1;j
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Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc
... control of gene expression As each step of the RNA metabolism is tightly regulated, the regulation of mRNA export, stability and translation rate is essential for the control of the expression of ... phenol ⁄ chloroform, once extracted with chloroform, and precipitated with ethanol and sodium acetate [62] The quality of the RNA samples was verified by agarose gel electrophoresis before loading ... Overexpression of ASF ⁄ SF2 down-regulates the expression of a reporter containing AU-rich elements (A) Schematic representation of the bidirectional FLuc ⁄ RLuc reporter constructs bearing (or...
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Tài liệu Reclaiming city streets for people Chaos or quality of life? ppt
... Europe a majority of citizens are calling for changes to promote modes of transport which are more respectful of their environment In 1999, 70 % of Europeans said they were more worried than ... Rigorous monitoring of the situation before and after implementation of the scheme was essential in providing evidence in support of the project (14) Dr Peter Pluschke, Head of Department for ... the construction of Tramline B The main aim of the plan was to reduce the dominance of the private car and to increase the use of more sustainable forms of transport, public transport, cycling and...
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Tài liệu Báo cáo khoa học: "A Comprehensive Dictionary of Multiword Expressions" doc
... a word string as an MWE, the logic being that an MWE expression is usually fixed in its form and the substitution of one of its constituent words would yield a meaningless expression or an expression ... Automatically Identifying Multiword Expressions in Corpora Proceedings of A Broader Perspective on Multiword Expressions, Workshop at the ACL 2007 Conference: 1–8 Baptista, J., Correia, A., and Fernandes, ... Linguistic Data Consortium 2003T10 Laporte, É and Voyatzi, S 2008 An Electronic Dictionary of French Multiword Adverbs Proceedings of the LREC Workshop towards a Shared Task for Multiword Expressions...
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