fungal infections of the skin
DERMATOLOGY: CLINICAL & BASIC SCIENCE SERIES BIOENGINEERING OF THE SKIN potx
... in the classification of skin lesions However, the image contains only the information from the skin surface, and strong reflections of light partly disturb the visibility of the lesion In the ... determine whether persons can be classified into skin types I–IV according to the lightness (L) of their skin We examined the skin color of sun-exposed regions (forehead, dorsum of the hand) and ... softens the horny layer Sebum production on the face adds lubricity, but can also make the skin look and feel greasy The temperature of the skin surface may also contribute to the appearance of...
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BIOENGINEERING OF THE SKIN Skin Biomechanics potx
... to 80% of the dry weight of skin consists of collagen The most abundant collagen types in skin are types I and III; the former accounts for 80% of the total collagen content of skin and the latter ... Thinning of the dermis Hyperextensible skin Thinning of skin Fragility of skin Osteogenesis imperfecta Thin, fragile skin Scleroderma Thickening and stiffening of skin Tumorlike thickening of skin ... the upward phase From this point, the residuaL extension can be measured Plammetry of the area below the upward curve, and of the area between the hysteresis loop, allows the calculation of the...
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Neuroimmunology of the Skin Basic Science to Clinical Practice ppt
... flow The autonomic innervation of the skin mostly belongs to the sympathetic division of the autonomic nervous system The postganglionic nerve fibers run in peripheral nerves to the skin, where they ... function The impact of the parasympathetic nervous system on the skin, however, is of negligible importance in humans The skin is › › › › This chapter describes anatomy and function of the sympathetic ... neurobiology of skin appendages and the role of the nervous system in the pathophysiology of skin disorders We believe that this book will be useful to investigators studying the effects of the nervous...
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color atlas of melanocytic lesions of the skin - h. soyer, et al., (springer, 2007)
... Diagnosis of Pigmented Lesions of the Skin The Board of the Consensus Netmeeting agreed on a two-step procedure for the classification of pigmented lesions of the skin (see Fig. I.3.7) [6] The first ... clues are the presence at the lateral edges of the lesion of conventional complexes of nevoid melanocytes, the restriction of the fibrotic changes to the center of it, and the absence of prominent ... R Hofmann-Wellenhof, R. H Johr (Eds.) Color Atlas of Melanocytic Lesions of the Skin H. P Soyer G Argenziano R Hofmann-Wellenhof R. H Johr (Eds.) Color Atlas of Melanocytic Lesions of the Skin...
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Báo cáo toán học: " Metabolite proving fungal cleavage of the aromatic core part of a fluoroquinolone antibiotic" pdf
... F-13 proves fungal cleavage of the aromatic fluoroquinolone core for the first time Hence, two decades after the emergence of the notion of the nonbiodegradability of fluoroquinolones, fungal degradation ... e.g., in the lipids of E coli (Goldfine 1982) Two decades after the emergence of the notion of the non-biodegradability of FQs, briefly reviewed by Wetzstein et al (2009), fungal degradation of all ... hydroxyl and the CN group, respectively, proved fungal cleavage of the aromatic FQ core for the first time The presence of a conjugated CN group was verified by IR-spectroscopy Being part of a mesomeric...
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báo cáo hóa học:" Metabolite proving fungal cleavage of the aromatic core part of a fluoroquinolone antibiotic" docx
... F-13 proves fungal cleavage of the aromatic fluoroquinolone core for the first time Hence, two decades after the emergence of the notion of the nonbiodegradability of fluoroquinolones, fungal degradation ... e.g., in the lipids of E coli (Goldfine 1982) Two decades after the emergence of the notion of the non-biodegradability of FQs, briefly reviewed by Wetzstein et al (2009), fungal degradation of all ... hydroxyl and the CN group, respectively, proved fungal cleavage of the aromatic FQ core for the first time The presence of a conjugated CN group was verified by IR-spectroscopy Being part of a mesomeric...
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Chapter 083. Cancer of the Skin (Part 1) ppt
... than lighterskinned whites In keeping with the role of sun exposure, the incidence is inversely correlated with the latitude of residence; at any latitude, darker-skinned persons have the lowest ... common cancer in men (5% of cancers) and the sixth most common in women (4% of cancers) The tumor can affect adults of all ages, even young individuals (starting in the mid-teens); has distinct ... excision is possible; and is located on the skin surface, where it is visible The incidence has increased dramatically (6% per year from 1973 to 1980, then 3% per year) Current lifetime risk...
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Chapter 083. Cancer of the Skin (Part 2) ppsx
... Superficial spreading melanoma is the most frequent variant observed in the white population Melanomas arising in dysplastic nevi (see below) are usually of this type The back is the most common site for ... melanomas can be amelanotic, in which case the diagnosis is established histologically after biopsy of a new or changing skin nodule or because of a suspicion of a basal cell carcinoma (see below) ... blue-black predominantly a During much of this time, the precursor stage, lentigo maligna, is confined to the epidermis Source: Adapted from AJ Sober, in Pathophysiology of Dermatologic Diseases, NA Soter,...
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Chapter 083. Cancer of the Skin (Part 4) pot
... other Shape Irregular borders; Round; sharp, clear-cut pigment may fade off into borders between the nevus and surrounding skin; macular the surrounding skin; may be portion at the edge of the ... Academy of Dermatology, the National Cancer Institute, and the Skin Cancer Foundation Self-examination at 6- to 8-week intervals may enhance the likelihood of detecting change The importance of routine ... Sun-exposed areas; the Generally on the sun- back is the most common site, exposed surfaces of the skin but dysplastic nevi may also be above the waist; the scalp, seen on the scalp, breasts, and breasts,...
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Chapter 083. Cancer of the Skin (Part 5) ppsx
... configuration The lesion may have an excess of thick, coarse hairs The risk of melanoma developing in these lesions is not known but appears to be relatively small The management of small- to ... D—diameter >6 mm (the size of a pencil eraser) Of these criteria, the weakest is diameter >6 mm since a significant fraction of melanomas are now diagnosed with diameters
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Chapter 083. Cancer of the Skin (Part 6) potx
... excision of the lesion with a margin of normal skin is necessary to remove all malignant cells and minimize possible local recurrence The appropriate width of the margin is a source of controversy ... bone pain The physical examination should be directed especially to the skin, regional draining lymph nodes, central nervous system, liver, and spleen In the absence of signs or symptoms of metastasis, ... node(s) from the primary site is/are identified by injecting a blue dye and a radioisotope around the primary site The initial draining node(s) is/are then identified by inspection of the nodal...
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Chapter 083. Cancer of the Skin (Part 7) doc
... 70–80% of NMSCs Squamous cell carcinomas (SCCs), while representing only ~20% of NMSC, are more significant because of their ability to metastasize (Fig 83-2); they account for most of the 2400 ... eroded plaque on the lower lip Sun-exposed skin such as the head, neck, hands, and arms are other typical sites of involvement C Actinic keratoses consists of hyperkeratotic erythematous papules ... disease may also prove applicable in the adjuvant setting The absence of curative therapy for patients with metastatic melanoma underscores the importance of early detection and prevention as...
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Chapter 083. Cancer of the Skin (Part 9) ppt
... decrease the rate of NMSC in xeroderma pigmentosum Squamous Cell Carcinoma The therapy of cutaneous SCC should be based on an analysis of risk factors influencing the biologic behavior of the tumor These ... These include the size, location, and degree of histologic differentiation of the tumor as well as the age and physical condition of the patient Surgical excision, MMS, and radiation therapy are ... unknown On the other hand, MMS, a specialized type of surgical excision that permits the best histologic control and preservation of uninvolved tissue, is associated with cure rates >98% It is the preferred...
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Chapter 083. Cancer of the Skin (Part 10) pps
... WH Jr et al: The histogenesis and biologic behavior of primary human malignant melanoma of the skin Cancer Res 29:705, 1969 [PMID: 5773814] Friedman RI et al (eds): Cancer of the Skin Philadelphia, ... 1991 ——— et al: Malignant melanoma in the 1990s: The continued importance of early detection and the role of physician examination and self-examination of the skin CA Cancer J Clin 1:201, 1991 Kirkwood ... interferon-a2a: Effective combination therapy for advanced squamous cell carcinoma of the skin J Natl Cancer Inst 84:235, 1992 [PMID: 1734084] Marks R: An overview of skin cancers Incidence and causation...
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Báo cáo khoa học: "Prognostic factors for lymph node metastasis from advanced squamous cell carcinoma of the skin of the trunk and extremities" doc
... over the time pre- The 24 cases of amputations (42.1%) also reflected the selection of local advanced disease Sixteen of 24 cases (66.7%) were T4 Most of them had no possibility to try other ... Carcinoma of the skin of the trunk and limbs: The incidence of metastases and their outcome Aust N Z J Surg 1992, 62:697-701 Ames FC, Hickey RC: Squamous cell carcinoma of the skin of the extremities ... was the only statistically significant factor: of 11 patients with preceding chronic skin lesion at the site of SCC presented lymph node metastasis, versus of 35 (p = 0.050) The mean time of presentation...
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Wound Healing and Ulcers of the Skin - part 1 pps
... algorithmic approach to the treatment of chronic wounds The caring of wounds has always been the realm of the various branches of surgery Dermatology, on the other hand, being the medical science ... Leaking of plasma through the permeable vessels into surrounding tissue causes the site of the injury to become swollen Due to the secretion of various chemical substances, the area may show other ... assist physicians in the treatment of chronic wounds, and that it will ultimately serve to reduce the immense suffering of those afflicted Note to the Reader Neither the authors nor the publishers...
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Wound Healing and Ulcers of the Skin - part 2 pptx
... establishment of the unique scientific branch of histopathology by Virchow [26] in the middle of the nineteenth century is the basis for our understanding of the processes of Fig 3.8 The significance of a ... GD: Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig Nature 1962; 193 : 293–294 30 Hinman CD, Maibach H: Effect of air exposure ... equilibrium between the synthesis of new stable collagen and the lysis of old collagen is the hallmark of this phase Collagen type III, synthesized in the first few weeks, is replaced by the more stable...
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Wound Healing and Ulcers of the Skin - part 3 ppsx
... glucocorticoid therapy may be detrimental to the quality of the skin in these cases, thus further hindering the repair of cutaneous ulcers Vasculitic involvement may induce ulceration in other connective ... morphological characteristics that may direct the physician to the underlying cause are (a) the appearance of the ulcer’s margin and (b) the appearance of the skin around the ulcer Fig 5.3 Bluish discoloration ... Seite 42 In addition to the above, numerous hypotheses have been put forward to explain the exact mechanism of skin damage and the development of ulceration in the presence of venous insufficiency...
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Wound Healing and Ulcers of the Skin - part 4 pot
... places The extent of undermining can be drawn on the skin around the ulcer These markings are important for assessing the progress of the ulcer and the effectiveness of treatment Additionally, the ... Assessment of the ulcer area Depth The presence and extent of undermining Parameters of wound/ulcer infection Assessment of the appearance of the ulcer surface Then we detail parameters of assessment ... Extravasation of red blood cells – secondary to injury of the blood vessels Other signs of damage to the wall may be present, such as the degeneration of collagen fibers, and the necrosis of endothelial...
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Wound Healing and Ulcers of the Skin - part 5 pot
... to the wound surface Removal of the dressing may then strip away newly forming epithelium [3] On the other hand, the probability of epithelial injury with the use of hydrogel or hydrocolloid dressings ... gangrenosum or other conditions associated with pathergy are present The term ‘pathergy’, in the context of debridement of cutaneous ulcers, refers to the formation of a new lesion or aggravation of existing ... Identification of pathergy, apart from the clinical impression of the worsening of ulcers following debridement, is made by the ‘pathergy test’ This is performed by pricking the skin with a sterile...
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