... the face of temperatureacclimation. Therefore, we think that the describedmechanism maintains either (a) the kinetic⁄ thermody-namic properties of this metabolic node by ‘dilution’ of the major ... All the observed dynamic changes in enzymeproperties under acclimation should be considered in the context ofthe relevance for the performance of metabolic networks, because the theory of metaboliccontrol ... Assemblage of the clones yield the full-length cDNA sequences of at least twodistinct LDH-A isoforms, which differ substantially in the coding sequence and length ofthe 3¢-UTR. Therefore, iso-form-specific...
... connected to the DEC1 E-boxes(Fig. 2), while deletion ofthe Orange domain ( DEC1DOr-ange) had no effect on the suppressive activity, indicating the importance of t he bHLH region of DEC1. The HXXXXXXXR ... conclude that the basic region, p artic-ularly the conserved A rg65, but not His57, is essential for the suppressive activity of DEC1.Determination ofthe binding domain of DEC1 to BMAL1 The interaction ... that the C-terminal region, including the PAS-Bdomain of BMAL1, is required for the binding to DEC1,Fig. 4. Identification ofthe domain of D EC1that interacts with BMAL 1. Interactions of various...
... Binding of CCE1 results in the complete unpairing ofthe four base-pairs in the centre of the junctions with a lesser disruption ofthe next base-pairs[19], which is reminiscent ofthe structure of ... 4 at the junction crossover – and the unpairing of four base-pairs in the centre ofthe junctions [19]. Detailedunderstanding ofthefunctional role of these interactionswould require the crystal ... manipulating the global conformation of the junction, then the deletion of this motif would have aneven more serious effect on Ydc2 binding in the presence of divalent cations. We tested the effect of...
... not worried about the future. But at the same time they possess the wisdom of the sages. We are the mirror of our thoughts. The serenity and vitality of the Hunzas proves that they have attained ... by the Hunzas to designate old age isextremely significant. They call it the ‘age of plenitude,’ the periodwhen people reap the just rewards of their labors. The first stage of life, called the ... utopia. They call themselves the Hunzas(pronounced Hoonzas) and live in what has come to be known as the roof ofthe world - the mountain peaks ofthe Himalayas. Tobe more precise, the Hunza...
... at the door. Hetepmes is the name of another there. Messep is the name of another there. Utchara is the name of another there. Beq is the name of another there. Anp (Anubis) is the name of ... the nose of Neb-nefu (the lord ofthe air), who giveth sustenance unto all mankind, on the day ofthe filling ofthe Utchat in Anu, in the second month ofthe season Pert, on the last ofthe ... with the rays of light upon my body day by day, upon me, Osiris the scribe, the assessor ofthe divine offerings of all the gods, the overseer ofthe granary ofthe Lords of Abydos, the real...
... faculties on the alert -- the fractious yelping ofthe coyotes, the ceaseless, low symphony ofthe wind, the distant booming ofthe frogs about the lake, the lamentation of a concertina in the Mexicans' ... ing. Think ofthe gallops over those leagues of prairies, with the wind tugging at the roots of your hair, the com- ing close to the earth and learning over again the stories ofthe growing ... showed himself on the floor ofthe gallery, and then, the screeches ofthe two women giving him his cue, he scuttled with all his yellow legs through the open door into the furthermost west room,...
... đã giúp Túy quyền II trở thành một " ;the last bow" xứng đáng cho sự nghiệp của Thành Long ở Hồng Kông. 04. Điệp huyết nhai đầu (Bullet in the Head - 1990, Ngô Vũ Sâm) Tính từ có ... 26. Người trong giang hồ (Young and Dangerous - 1996, Lưu Vỹ Cường) Best Hong Kong films ofthe 90s Tiếp nối loạt bình chọn Phim HK hay nhất thập niên 2000, trang LoveHKFilm.com lại ... Hồng Kông, hay chính xác hơn là phim hài "kiểu Châu Tinh Trì". 24. Bạch phát ma nữ (The Bride with White Hair - 1994, Vu Nhân Thái) Trương Quốc Vinh + Lâm Thanh Hà ở đỉnh cao của...
... while I was standing on the edge ofthe wooden sidewalk, down out ofthe sky falls two fine gold watches in the middle ofthe street. One hits a chunk of mud and sticks. The other falls hard and ... the prince's coffers. I first saw Mr. Polk coming down the steps ofthe hotel at which sojourned His Highness the Gaekwar of Baroda, most enlightened ofthe Mahratta princes, who, of ... 'They're a funny lot of post-cards, aren't they?' "'Oh, I wasn't thinking of them dudes and culls on the hoof,' says he. 'I was thinking of the...
... o'clock the coffee was made and the frying-pan was on the back ofthe stove hot and ready to cook the chops. Jim was never late. Della doubled the fob chain in her hand and sat on the corner of ... gifts to the Babe in the manger. They invented the art of giving Christmas presents. Being wise, their gifts were no doubt wise ones, possibly bearing the privilege of exchange in case of duplication. ... to you the uneventful chronicle of two foolish children in a flat who most unwisely sacrificed for each other the greatest treasures of their house. But in a last word to the wise of these days...
... those ofthe Toadflax are slender and drooping. There is a large mass of it on the side ofthe wall, and we find that the root is at the highest point ofthe whole mass. The stems with the flowers ... something the shape of a horseshoe. The leaves ofthe White Clover grow, like the flower, at the top ofthe stem a single leaf on each stem. The under sides ofthe leaves are smooth and glossy. The ... moisture either. Yet the leaves of several of them are thick and fleshy, and the flowers of some are large and beautiful. What could be more handsome than the blossoms ofthe Wallflower, the Red...
... respectively, of that of HPRT. This low activitycould be explained by the fact that PRTFDC1 has a Gly in the position of the proposed catalytic Asp of HPRT. In PRTFDC1, a water molecule at the position of ... strength [20].In the present study, we report the structural and functional characterization ofthe human HPRThomolog PRTFDC1. To shed light on the potentialfunction of PRTFDC1, the protein was ... interacts with bothO6 and N7 (Fig. 1C). The 2¢OH ofthe ribose is hydro-gen bonded to the main chain and the side chain of Asp142 (Fig. 1C). Both hydroxyl groups ofthe riboseare involved in coordinating...