founder of double entry bookkeeping
Báo cáo khoa học: Viral entry mechanisms: the increasing diversity of paramyxovirus entry doc
... increased greatly with theelucidation of the crystal structures of the prefusionform of the PIV5 F protein [89] and of the postulatedpostfusion forms of the NDV and hPIV3 F proteins[90–92]. ... University of Kentucky, Lexington, KY, USAIntroductionThe paramyxovirus family is composed of enveloped,negative-stranded RNA viruses, many of which aremajor human pathogens [1]. Members of this ... promote the processes of viralattachment and virus-cell membrane fusion required for entry. Althoughcommon mechanisms of fusion protein proteolytic activation and the mech-anism of membrane fusion...
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Báo cáo khoa học: Modulation of Ca2+ entry and plasma membrane potential by human TRPM4b pptx
... apositive regulator of Ca2+ entry. The upregulation of TRPM4b might then be involved in the furtherprogression of the tumor. Such a possible role of ABFig. 3. Ca2+release and Ca2+ entry induced ... to act as a negative regulator of Ca2+ entry andto be involved in the generation of oscillations of Ca2+influx in JurkatT-lymphocytes. Transient overexpression of TRPM4b as an enhancedgreen ... influence of fused EGFP on channelfunction (compare Fig. 1D with Fig. 2A,B).Generation of HEK-293 clones with stableexpression of TRPM4bTo investigate the effect of TRPM4b expression onCa2+entry...
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The Founder of New France: A Chronicle of Champlain pot
... final til midnight of the last day of the month of any suchannouncement. The official release date of all Project Gutenberg Etexts is at Midnight, Central Time, of thelast day of the stated month. ... seventeenth century, but the founder of Quebec;and it is a rich part of our heritage that he founded New France in the spirit of unselfishness, of loyalty, and of faith.BIBLIOGRAPHICAL NOTEOriginal ... excitement of sailing among the uncharted islands of Penobscot Bay, of watching the sun descend below the waves of Lake Huron, of attacking the Iroquois in theirpalisaded stronghold, of seeing...
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Báo cáo khoa học: " Medication errors: a prospective cohort study of hand-written and computerised physician order entry in the intensive care unit"
... remit of the local ethics committee. Prior tointroduction of CPOE, local standards of prescribing existedspecifying the tenets of good practice, including the avoid-ance of the use of abbreviations.An ... administered asTable 1Types of medication errors before and after implementing CPOEError type HWP (no. of errors and % of total errors)aCPOE (no. of errors and % of total errors)aDrug prescribed ... The types of error appeared to change with the intro-duction of CPOE.• The introduction of CPOE without decision support eliminated many minor types of error but introduced new types of error...
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Báo cáo khoa học: "Impact of computerized physician order entry on medication prescription errors in the intensive care unit: a controlled cross-sectional trial"
... 1Scatter plot of number of medication prescribing errors (MPEs) at screening day according to number of drug orders per patient (24 hour screening day)Scatter plot of number of medication prescribing ... example of intercepted MPEinvolved the wrong prescription of a tenfold overdose of abeta-blocker, where rapid intervention of the clinical pharma-cist intercepted the administration of this ... one unit of our ICU, we implemented an ICIS with incorpo-rated CPOE and a moderate level of CDSS. The objective of this study was to evaluate and compare the incidence andseverity of medication...
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Báo cáo y học: "omparative Efficacy and Tolerability of 5-Loxin® and Aflapin® Against Osteoarthritis of the Knee: A Double Blind, Randomized, Placebo Controlled Clinical Study"
... Sarma KV, Dey D, Raychaudhuri SP. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee. Arthritis Res. Ther. ... Equal number of HCH cells was plated in each well of 96-well cell culture plate. Cells were treated with 5 ng/ml of TNFα in presence or absence of different concentrations of 5-Loxin® or ... medical management of osteoarthritis. Part II. Osteoarthritis of the knee. American College of Rheumatology. Arthritis Rheum. 1995; 38: 1541-1546. 5. American College of Rheumatology Subcommittee...
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Báo cáo y học: " Evaluation of Lumbar Facet Joint Nerve Blocks in Managing Chronic Low Back Pain: A Randomized, Double-Blind, Controlled Trial with a 2-Year Follow-U"
... pre-valence of low back pain of 162% with an annual in-crease of 11.6%. The widely held belief that most of the episodes of low back pain will be short-lived, with 80% to 90% of these attacks ... Classification of Chronic Pain; Descriptions of Chronic Pain Syndromes and Definition of Pain Terms, 2nd ed; Task Force on Taxonomy of the International Association for the Study of Pain. Seattle: ... pain of facet joint origin. Summary of Background Data: Lumbar facet joints have been shown as the source of chronic pain in 21% to 41% of low back patients with an average prevalence of 31%...
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ENTRY STRATEGY INTO VIETNAMESE ENVIRONMENTAL MARKET A CASE STUDY OF ALTECH ENVIRONMENT PTE LTD
... 52.1.1 Entry strategy 52.1.2. Elements of Entry Strategies 62.1.3. Mode of Entry 72.1.4. Advantages and Disadvantages of each entry mode 112.2 DISCUSSION: PROBLEMS AND SOME EXTENSIONS OF THE ... a trade-off between the two types of risk. The acquisition of control is often at the expense of increased exposure toenvironmental risk.2.1.4. Advantages and Disadvantages of each entry mode ... analysis of the impact of country -of- origin effects onthe market entry decision would constitute a useful addition to the literature. 2.3. Environmental Technology Industry2.3.1. An era of environmental...
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Tài liệu Báo cáo khoa học: Catalytic mechanism of SGAP, a double-zinc aminopeptidase from Streptomyces griseus pdf
... hydro-lysis of Leu-pNA. The enthalpy of ionization, DHion¼ 30 kJÆmol)1,was calculated from the slope of the line.ABFig. 4. Inhibition of SGAP by fluoride. (A) A representative plot of the Lineweaver–Burk ... This value is in the range of the expected ioniza-tion of a zinc-bound water ⁄ hydroxide in solution,DHion of 20–30 kJÆmol)1[52]. The enthalpy of ioniza-tion of a carboxylic group is much ... thepresence of D2O in solution reduced the catalyticABFig. 5. Inhibition of SGAP by phosphate ion. (A) A representativeplot of a Lineweaver–Burk plot for determination of the mode of inhibition...
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Tài liệu Báo cáo khóa học: Further insights into the assembly of the yeast cytochrome bc1 complex based on analysis of single and double deletion mutants lacking supernumerary subunits and cytochrome b pdf
... yeastmutants containing double deletions of supernumerarysubunits. Deletion of any one of the genes encoding cyto-chrome b, subunit 7 or subunit 8 caused the loss of the othertwo subunits. ... unaffected. Therefore, the absence of subunit 6 appeared to alter the rates of processing of two of the redox subunits and caused minor changes in amounts of the small supernumerary subunits, ... D6/D7 double deletion strain(VZ4) exhibited the strongest defect in the assembly of thecatalytic subunits of cytochrome bc1complex. This strainshowed only 18% and 6% of the wild-type levels of...
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Tài liệu Báo cáo Y học: Mutations in the docking site for cytochrome c on the Paracoccus heme aa3 oxidase Electron entry and kinetic phases of the reaction pptx
... of singlemutants in each of the two positions, or of double mutants,was generated (Table 1). While Kmvalues for all complexesdo not deviate from that of wild-type by more than a factor of ... complex of therespiratory chains of mitochondria and many bacteria[1–4]. It catalyzes the reduction of oxygen to water, couplingthe free energy of this reaction to the generation of a protongradient ... Germany;2Department of Basic and Applied Biology, University of L’Aquila, ItalyIntroducing site-directed mutations in surface-exposedresidues of subunit II of the heme aa3cytochrome c oxidase of Paracoccus...
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