Ngày tải lên :
18/06/2014, 16:20
... Gd–DTPA
2–
and Gd(HP-DO3A) produced no lethality up to
200 g/L, and Gd(CPA-DO3A)
–
producedlethalityof17 %and3 1%at 24- hourexpo-
suresof100g/Land200g/L.
34
Thetoxicityofmetalsandtheirchelatesisinuencedbytheuptakeintothe
organisms. ... particle
counter(“CoulterCounter”)atapproximately 24, 48 ,and7 2hours.ThepHvalue
wasmeasuredatthebeginningandattheendofthetest.
For the study with dimeglumine gadopentetate and gadofosveset trisodium, an
incubatingapparatus(AbimedAlgenTestXT)wasused.Inthiscasethecellnumber
was ... concentrations
were0,1.25,2 ,4, 10,20 ,and1 00mg/Lforthetestcompounddimegluminegado-
pentetate; 0, 40 , 88, 1 94, 42 6, 937, and 2062 mg/L for the test compound gadobutrol;
0, 2, 4, 10, 20, 40 , and 80 mg/L for the test compound gadofosveset trisodium; and
63, 125, 250, 500, and 1000...