for example t3 and or histological grade 3 tumours and good performance s
Early and locally advanced breast cancer - Diagnosis and treatment pdf
Ngày tải lên :
22/03/2014, 16:21
... factors 1.6.1 Assess oestrogen receptor (ER) status of all invasive breast cancers, using immunohistochemistry with a standardised and qualitatively assured methodology, and report the results ... is made by triple assessment (clinical assessment, mammography and/ or ultrasound imaging, and core biopsy and/ or fine needle aspiration cytology) It is best practice to carry out these assessments ... www.nice.org.uk/guidelinesprocess or from NICE publications (phone 0845 0 03 77 83 or email publications@nice.org.uk and quote reference N1 233 ) Implementation The Healthcare Commission assesses the performance of NHS organisations...
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Báo cáo y học: " Parental and household smoking and the increased risk of bronchitis, bronchiolitis and other lower respiratory infections in infancy: systematic review and meta-analysis" ppsx
Ngày tải lên :
12/08/2014, 13:22
... disease risk (cohort studies: OR 1.47, 95% CI 1 .33 to 1.62; 17 studies; cross-sectional studies: OR 1.49, 95% CI 1.28 to 1.74; 11 studies; case-control studies: OR 2.01, 95% CI 1 .31 to 3. 10; studies) ... 1.45; 13 studies) In a sub-group analysis based on method of ascertainment of passive smoke exposure, similar pooled estimates for both self-reported (OR 1.24, 95% CI 1. 13 to 1 .36 ; 17 studies) and ... included studies [17-47] used data from cohorts, primarily birth cohorts; 15 studies [48-62] used a case-control design and 13 studies [ 63- 75] were crosssectional surveys The LRI outcome reported was...
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Alterations of matrix metalloproteinases in the healthy elderly with increased risk of prodromal Alzheimer’s disease pot
Ngày tải lên :
22/03/2014, 14:20
... Statistics Statistical analysis was performed using the PASW software (former SPSS software, version 17.0.1 for Windows, SPSS Inc., Chicago, IL, USA) Non-parametric tests were used because normal ... laboratory assistant Marit Emilsson for assistance in the TIMP-1 analysis This study was supported by unconditional grants by the Swedish Research Council; Stiftelsen för Gamla Tjänarinnor; Skåne ... present study the cognitive assessment also included the Alzheimer s Disease Assessment Scale (ADAS-cog 85 points), clock test, cube copying test and A Quick Test of cognitive speed (AQT) These...
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Tài liệu Báo cáo khoa học: Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines docx
Ngày tải lên :
19/02/2014, 05:20
... for HeLa cells and 80 pmol for HepG2 cells, cultured in a 9-cm dish for the indicated hours of incubation The effects of siRNA were assessed by northern blot and western blot analyses To construct ... antibody This study was supported by Grantsin-aid for Scientific Research (B), for Scientific Research on Priority Areas, and by the 21st Century COE Program Special Research Grant ‘the Center for Innovative ... other investigators [32 ], was also used GAPDH siRNA, named siGAPDH, was used as a control for siRNA When HeLa or HepG2 cells were 50% confluent, they were treated for 24 h with each siRNA by using...
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Báo cáo khoa học: "Increased expression of osteopontin in the spinal cords of Lewis rats with experimental autoimmune neuritis" doc
Ngày tải lên :
07/08/2014, 18:20
... guidelines for the care and use of laboratory animals Tissue sampling To study OPN expression in animals with EAN, spinal cord tissue and sciatic nerves were sampled during paraparesis (day 14-18 post-immunization) ... paraparesis Glial cells, subarachnoid macrophages and neurons in the spinal cord express OPN and CD44 in EAN Immunohistochemistry showed expression of OPN in some cells in the spinal cord parenchyma ... Immunostaining for ED1 and GFAP in the normal (A and B) and EAN-affected spinal cords (C and D) In normal rat spinal cords, there were few ED1-positive macrophages, and GFAPpositive cells (astrocytes)...
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Báo cáo khoa học: "Increased phosphorylation of c-Jun NH (2)-terminal protein kinase in the sciatic nerves of Lewis rats with experimental autoimmune neuritis" ppt
Ngày tải lên :
07/08/2014, 18:21
... noisserpxe 00 1S dna 1DE ,KNJ-p dna sisotpopa fo gniniats elbuoD )sworra ,C3 giF( IP 42 yad ta sevren citaics detceffa-NAE ni )sworra ,A3 giF( KNJ -p sserpxe segahporcam taht gnitseggus ,)sworra ... erew star detceffa-NAE dna lortnoc morf sevren citaics fo )mµ 5( snoitces eussit niffaraP yrtsimehcotsihonummI tnacifingis deredisnoc erew 50.0 naht ssel seulav htiw secnereffid ,sesac lla nI tset ... desaercnI -sohp eht taht detartsnomed ew ,yduts suoiverp ruo nI ]3[ yduts suoiverp a ni nwohs sa ,KNJ fo noitavitca eht hguorht sisotpopa morf deucser erew yduts tneserp eht ni NAE gnirud sllec...
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Báo cáo y học: " Female smokers beyond the perimenopausal period are at increased risk of chronic obstructive pulmonary disease: a systematic review and meta-analysis" ppsx
Ngày tải lên :
12/08/2014, 16:20
... category as the weights All tests were two-tailed in nature and were performed using statistical software SAS (version 9.1, SAS Institute, Carey, N.C) Results A summary of the search strategy is shown ... design sensitive terms (cohort studies, longitudinal studies, follow-up studies, prospective studies), and smoking sensitive terms (smoke, cigarette, smoking) in our searches The electronic searches ... smokers and former smokers were combined as non-smokers in the article since they did not differ in FEV1% pred decline fied by gender and smoking status We excluded cross-sectional studies, or...
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Báo cáo y học: "High serum cortisol level is associated with increased risk of delirium after coronary artery bypass graft surgery: a prospective cohort study" pps
Ngày tải lên :
14/08/2014, 07:21
... performed Delirium assessment Delirium assessment was performed in two steps First, level of sedation (level of arousal) was assessed by means of the Richmond Agitation Sedation Scale (RASS) ... drowsy) If the patient was deeply sedated or was unarousable (-4 or -5 on the RASS), assessment was stopped and then was repeated later If RASS was above -4 ( -3 through +4), assessment was continued ... pathogenesis of postoperative delirium Cortisol is one of the most important stress hormones in humans Its secretion is proportional and positively correlated to the severity of surgical stimuli...
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Báo cáo y học: " Endothelial Endotoxemia related to cardiopulmonary bypass is associated with increased risk of infection after cardiac surgery: a prospective observational stud" pptx
Ngày tải lên :
14/08/2014, 07:21
... two-sided and statistical significance was assumed for a P-value of ≤ 0.05 Analyses were performed using SAS version 9.2 (SAS Institute Inc., Cary, NC, USA) 85.2 57.5 (8.1) 35 .2 46 .3 30 .34 (5.41) ... Hyperlipidemia Statistical analysis Means, standard deviations and proportions were used to describe patients’ characteristics Group differences were examined using the chi-square or Fisher s exact test ... Nevertheless, previous studies similarly did not correct for hemodilution and thus we did not to so for comparative purposes We are not aware of any validated correction factor for hemodilution for...
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Báo cáo y học: "No increased risk of infant hypospadias after maternal use of loratadine in early pregnancy"
Ngày tải lên :
31/10/2012, 17:03
... is formally statistically significant As there is no prior hypothesis and at the surveillance process we study a large number of “exposures” (in this case drugs) and many outcomes (in this case ... uncertain exposure information and in spite of its size of 31 9 hypospadias cases found an adjusted OR for hypospadias after loratadine exposure during the first Present evidence suggests that the ... publish or not to publish and also how such a finding should be handled by authorities If such a “signal” is published it is imperative to stress that in spite of formal statistical significance, the...
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Báo cáo y học: "An Increased Risk of Osteoporosis during Acquired Immunodeficiency Syndrome"
Ngày tải lên :
03/11/2012, 09:54
... conditions, or diseases [3] Many of the commonly occurring diseases like endocrine disorders, malabsorption disorders, bone marrow disorders and inflammatory diseases were reported to be associated ... patterns of osteoporosis across the world In: Chesnut CH III, ed Proceedings of the Second Asian Symposium on Osteoporosis- New Dimensions in Osteoporosis in the 199 0s Hong Kong: Excerpta Medica Asia ... the hip and spine and with the risk of fracture In patients with osteoporosis, there is a four fold to five fold increase in risk for fracture And for patients with osteoporosis and a history of...
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Tài liệu Báo cáo " The extreme value of local dimension of convolution of the cantor measure" docx
Ngày tải lên :
13/02/2014, 03:20
... (2, 3, , 2, 3, 3) we get (y1 − 2)3n−2 + (y2 − 3) 3n 3 + + (yn−2 − 3) 3 − = Hence, (y1 − 2)3n−2 + (y2 − 3) 3n 3 + + (yn 3 − 2 )3 + yn−2 − = (3) (y1 − 2)3n−4 + (y2 − 3) 3n 3 + + (yn−4 − 3) 3 + yn 3 ... 0806042 732 8 3. 25 3 and a1, a2, a3 are roots of the following system of three equations X3 = µ1 (s1 ) = a1 X1 + a2 X2 + a3 X3 2 µ2 (s2 ) = a1 X1 + a2 X2 + a3 X3 3 3 (s3 ) = a1 X1 + a2 X2 + a3 X3 , where ... Theorem is divided in to two steps In Section 2.1 we will give some notations and primary results The Main Theorem is proved in Section 2.2 2.1 Notations and Primary Results Let ν be the standard...
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Tài liệu Báo cáo khoa học: "THE BY RESOLUTION OF LOCAL SYNTACTIC AMBIGUITY THE HUMAN SENTENCE PROCESSING MECHANISM" doc
Ngày tải lên :
22/02/2014, 09:20
... purport either to investigate syntactic processing empirically, or to model it computationally, should not ignore the role or the r e q u i r e m e n t s of these processes To so is to study something ... relative must therefore be matched against information which already exists in the hearer 's model of the universe This matching process presumably requires a certain amount of inferencing, or " b ... v e c l a u s e analysis is initially chosen, these examples take longer to process (via a reading time measure) than when the complement analysis is chosen (e.g Wanner, Kaplan, & Shiner, 1974;...
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Báo cáo Y học: Subsite mapping of the binding region of a-amylases with a computer program ppt
Ngày tải lên :
08/03/2014, 09:20
... stable and is not hydrolysed by a-amylases therefore, the products of hydrolysis are always b-glycosides Selection of these glycosides as substrates has been based on their size (DP 4–10) and good ... maltooligosaccharide series and only a few subsite maps have been evaluated for a-amylases until now [5,6, 13] Our b-CNP-maltooligosaccharides have turned out to be good substrates for further studies ... calculations show a barrier site for the same subsite The reason of this disagreement might be the absence of minimization or the relatively short substrates used There is a very interesting proposal...
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A study in the growth mechanism of silicon nanowires with or without metal catalyst
Ngày tải lên :
16/03/2014, 15:09
... is observed as shown in Fig 3A In addition, the asformed SiNW is easily oxidized with an oxide shell of 1 3 nm according to the Eq (2) (Fig 3A) 3. 2 Sulfide-assisted growth of SiNWs (3) Si is ... The samples were analyzed by scanning electron microscopy (SEM, JSM-5610LV) and transmission electron microscopy (TEM, JEM2100F) Results and discussion 3. 1 Metal-assisted growth of SiNWs A basic ... Fig A) The growth sketch of sulfide-assisted mechanism B) SEM image of SiNWs synthesized by sulfide-assisted growth developed a novel sulfide-assisted mechanism to synthesize SiNWs in large quantity...
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Báo cáo khoa học: "THE RECOGNITION CAPACITY OF LOCAL SYNTACTIC CONSTRAINTS" ppt
Ngày tải lên :
18/03/2014, 02:20
... assume that a preliminary morphological phase separated word-forms to basic sequences of tags, and then state syntactic rules in terms of standard word classes able for derivations), and a set ... "learn" and improve its performance as more text is processed (e.g by using the already tagged corpus as a statistical knowledge base) Arguments such as those given in sections and above suggest that ... local syntactic constraints can provide for practical parsers is "an oracle" which makes "educated guesses ~ about unknown words It is typical for language analysis systems to assume a noun whenever...
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Đề tài " On the K-theory of local fields " ppt
Ngày tải lên :
22/03/2014, 15:21
... null-object and taking the monomorphisms as the cofibrations and the isomorphisms as the weak equivalences Let E be an additive category embedded as a full subcategory of A, and assume that for every ... there is a map of graded k-algebras as stated We show that this is an isomorphism Suppose first that p divides eK We know from Proposition 2 .3. 4 that the map of the statement is an isomorphism in ... isomorphism of bi-simplicial categories with cofi- 14 LARS HESSELHOLT AND IB MADSEN brations and weak equivalences N· S C ∼ S N· C, = (1.2.1) where S C is Waldhausen s construction, [48, §1 .3] ...
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Báo cáo khoa học: The specificity of alcohol dehydrogenase with cis-retinoids Activity with 11-cis-retinol and localization in retina docx
Ngày tải lên :
23/03/2014, 12:20
... mouse ADH1 and ADH4 enzymes (Tables and 3, respectively) Except for the 13- cis isomers, all enzymes showed similar Km values for all retinoids assayed, ranging from to 35 lM for retinols and from ... with MnO2 [34 ] For the synthesized retinoids, the retinals were the forms of storage Synthesis of 7-cis-retinol, 9-cis-retinol and 11-cisretinol were performed by reduction of the corresponding ... were performed as reported previously [38 ] Results Substrate-docking simulations Docking simulations were performed in a Silicon Graphics Indigo R10000 workstation, using the ICM program (version...
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