... assays may miss a relevant number of SSc patients that are positive for PM/Scl aabs likely requires elucidation and further study Page of (page number not for citation purposes) The findings of ... characteristics ofthe new LIA and multicentre systematic studies that evaluate multiple clinical associations (especially the presence or absence of myositis) are needed for a consensus ofthe clinical value ... 422-427 Gutierrez-Ramos R, Gonz Lez-Diaz V, Pacheco-Tovar MG, LopezLuna A, Avalos-Diaz E, Herrera-Esparza R: A dermatomyositis and scleroderma overlap syndrome with a remarkable high titer of anti-exosome...
... could not be concluded that the PPV of one of these cut-off values is statistically superior to the others The specificity was significantly different between the cut-off of two or more erosive joints ... predictive valueofthe number of erosive joints but also performed the analyses using the erosion score ofthe Sharp/van der Heijde scoring (SHS) method in which the size and number of erosions ... (because the presence of hand erosions are part ofthe ACR criteria), we also tested the ability ofthe presence of erosive joints to predict disease persistency, defined as the absence of sustained...
... (extremely easy) the difficulty ofthe choice tasks Finally, they were asked to briefly describe the appropriateness of DCE in implementation research We calculated the mean number of minutes ... breast cancer surgery in day care Furthermore, respondents could select the 'neither' option if they did not find any ofthe two profiles acceptable for implementation For an example of a discrete ... analyzed Nearly all attributes were significant at the 1% level, implying that these attributes are relevant to the implementation ofthe guideline for breast cancer surgery in day care Only the...
... Appearance of excess lactate in anesthetized dogs during anemic and hypoxic hypoxia American Journal of Physiology 1965, 209:604-608 25 Cain SM: Oxygen delivery and uptake in dogs during anemic and hypoxic ... multivariable Cox PH model Ofthe variables, only the change in lactate level and the GCS were independently associated with in-hospital mortality (Table 3) The hazard of death decreased by 80% (95% CI = ... detection of occult shock and earlier start of goal-directed therapy References 10 11 12 13 14 15 16 Rady MY, Rivers EP, Nowak RM: Resuscitation ofthe critically ill in the ED: responses of blood...
... levels of fibrosis [10] The aim of this study was to summarize the diagnostic valueof these tests by an overview ofthe scientific literature and to respond to the following frequently asked ... cirrhosis The grading of activity by the METAVIR system (based on the intensity of necroinflammatory activity, mainly on necrosis) was scored as follows: A0 = no necroinflammatory activity, A1 = ... concerning the predictive values for the intermediate stages of fibrosis Contrary to the initial hypothesis, the diagnostic values of FT-AT for consecutive stages of fibrosis and grades of necroinflammatory...
... Results of a prospective nationwide survey For the Group of Epidemiology ofthe French Association for the Study ofthe Liver (AFEF) Hepatology 2000, 32:477-481 Afdhal NH: Biopsy or biomarkers: is there ... highlight the utility of a new panel of biochemical markers (ST) for the prediction of steatosis of different origins A cut-off of 0.30 had 90% sensibility and a cut-off of 0.72 had 90% specificity permitting ... Statistical Systems 2003 software (NCSS, Kaysville, Utah, USA) was used for all analyses [47] A sensitivity analysis was also performed for determining the accuracy ofthe markers for the primary outcomes...
... significantly elevated (Table 3) At the end ofthe first week ofthe ICU stay, there was only significant elevation of mean valueof CRP in septic patients There was no significant change in the mean value ... to the degree of dysfunction/failure The aggregate score (total maximum SOFA score (TMS) is calculated, summing up the worst scores for each ofthe organ systems (TMSorg) during the ICU stay [10] ... patients participating in the study or from their relatives The study was conducted over a period of nine months in the ICU of Emergency Hospital of Tanta University, Tanta, Egypt, which is a 25-bed...
... http://ccforum.com/content/15/3/R127 Page of error for each analysis The ratio ofthe Wald statistics can be interpreted as the gain in information density and is, therefore, a suitable measure for the efficiency ofthe different ... applied to the analysis of clinical trials on a regular basis The sliding dichotomy approach was recently applied for the primary efficacy in a number of trials: the PAIS trial in stroke [19], the STICH ... disability; GR, good recovery predictors [13] We, therefore, incorporated covariate adjustment in all analyses in the present study Why is the use of ordinal outcome analysis beneficial? The common...
... from the analysis During the study period no attempt was made to alter the daily routine strategy The study protocol was approved by the local ethics committee During the study period, daily routine ... expected finding' was any old finding predicted by the attending physician; a 'new unexpected finding' was any new finding not predicted by the attending physician; and an 'old unexpected finding' ... Incidences of CXR-induced changes were noticeably lower in our study, however, which may be explained by the fact that physicians were not asked whether they would make changes in daily management of their...
... Case yn−2 = 1, then yn−2 − = −3 and (yn−2 , yn−1 , yn ) = (4, 0, 0) From (3), we get Therefore, (y1 , , yn−3) ∈ (2, 3, , 2, 3, 3) By similar argument, we get yn−3 = or yn−3 = +) If yn−3 = then (yn−3 ... Conversely, if (y1 , , yn) ∈ (2, 3, , 2, 3, 2, 2) then we have (y1 − 2)3n−1 + (y2 − 3)3n−2 + + (yn−1 − 2)3 + yn − = (9) Hence, yn = or yn = a) If yn = then yn − = Hence, from (9), we get (y1 , , yn−1) ... implies that yn−1 = or yn−1 = a) If yn−1 = then yn−1 − = and (y1 − 2)3n−2 + (y2 − 3)3n−3 + + (yn−3 − 3)3 + (yn−2 − 3) = Therefore, (y1 , , yn−2) ∼ (2, 3, , 2, 3) = (x1 , , xn−2) and (yn−1 , yn ) =...
... possibly operate credibly given the existing money supply By 1994, 82 commercial banks held operating licenses, many of them far short ofthe amount of capital required on deposit with the Central ... remember the day that everything they had saved in the form of money was made worthless has reinforced an existing predisposition to reject currency as a store ofvalue Traditionally in Cambodian ... society where traditionally loans were secured from kin without interest, but in this case the unfairness ofthe terms and the cycle of debt they produced created animosity Farmers kept only small...
... by the economic valueof 12 better performance Such evaluations, however, provide some idea ofthe social valueof highly effective teachers, even if they not necessarily pinpoint the efficacy ... academic year due solely to the teacher to which they are assigned If a bad year is compounded by other bad years, it may not be possible for the student to recover No other attribute of schools ... they have fallen dramatically in relation to the rest ofthe economy The changing position of teachers is clear in salary trends since the beginning of World War II Compared to the earnings of...
... approaches to prove the effects ofthe K9 deletion on the ionization of catalytic residues and the overall stability ofthe enzyme This investigation contributes to the unraveling ofthe mechanisms ... Eqns (2–4) involved in the hydrolysis ofthe synthetic substrate D-Phe-Pip-Arg-pNA (B) at 25 °C in the presence of 0.15 M NaCl The best-fit pKa values ofthe ionizable groups of both WT and DK9 mutant ... expresses the acylation rate By contrast, the decrease in the DK9 Km value is consistent with better accommodation ofthe substrate into the catalytic pocket ofthe unprotonated form ofthe mutant,...
... and their many shapes are only phenomenal and ephemeral, but the Idea ofthe clouds is “that as elastic vapour they are pressed together, driven off, spread out, and torn apart by the force ofthe ... manifestations ofthe World Will: The possibility of [the] anticipation ofthe beautiful a priori by the artist, as well as of its recognition a posteriori by the connoisseur, is to be found in the fact ... follow under the guidance ofthe forms ofthe principle of sufficient reason [i.e forms of space, time, causality] merely their relations to one another, whose final goal is always the relation...
... The Tm of proCPY was higher by °C than that of Dgly proCPY, indicating that the carbohydrate moiety exerts a slightly protective effect on the thermal unfolding of proCPY The Pm value for CPY ... unfolding of CPY and proCPY Fig Temperature-induced changes in the centre ofthe spectral mass of (A) proCPY (d) and Dgly proCPY (s) and (B) CPY (d) and Dgly CPY (s) Fluorescence ofthe enzymes ... that of its unglycosylated form, though the DV and DGP values were almost the same The Pm valueof proCPY was higher than that of its unglycosylated form This is due to the higher DV valueof the...
... This is due to the energy valueof PV and CSP0 falling faster than the energy valueof wind while the capacity valueof wind remains slightly higher than the capacity valueof PV and CSP0 at ... sum ofthe total energy sold and the total energy curtailed) The capacity value is also shown in $/kW-yr terms to illustrate the annual capacity value per unit of nameplate capacity • Capacity Value ... Regents ofthe University of California, nor any of their employees, makes any warranty, express or implied, or assumes any legal responsibility for the accuracy, completeness, or usefulness of any...
... only to citizens Naturalized citizens can vote and run for public office; they receive protection from deportation and from losing their residence rights; and they enjoy other rights, such as the ... citizenship and the barriers to doing so Among the key findings: For a variety of reasons, naturalized citizens earn more than their noncitizen counterparts, are less likely to be unemployed, ... citizens through naturalization During the naturalization process, aspiring citizens must typically demonstrate that they have achieved a certain level of integration into the host society by meeting...
... Tipene "They were very angry over the killing of those others I'm just risking my life without the possibility of gain." "You obey my orders, or you go down and stay there," I said abruptly "Which?" ... ordered the two ray operators "We'll have to think up a better plan." 22 They turned off into the passage they had swept clean with their ray, and the rest ofthe party followed swiftly A few yards ... hundred yards away; laying down a deadly and impassable barrage on either side of us "They got Tipene, sir!" said Correy "He dodged out ahead ofthe ray men, and two of them pounced on him They were...
... cover in the city’s 7,999 acres of parkland Their aesthetic value is not countable, but thevalueofthe air pollution they extract is The Air Quality Calculator determined that they removed ... parks—roadways, trails, parking lots, buildings, and hard courts Second, the same photographs are then analyzed for the amount of perviousness ofthe rest of a city—in other words, the city without ... Certainly, not all park activities would take place if they had to be purchased On the other hand, city dwellers get pleasure and satisfaction from their use ofthe parks If they had to pay and if they...