... source are adult stem cells, in particular, bone-marrow-derived mesenchymalstemcells (MSCs) The use of these cells would allow an autologous approach, reducing the risk of rejection and infection ... field of view was performed to enable identification of GFP-positive cellsand immunopositivity for matrix proteins in the same cells Results Identification of injected mesenchymalstemcells ... disc-like cells from adult mesenchymalstemcellsStemCells 2005, 23:403-411 44 Risbud MV, Albert TJ, Guttapalli A, Vresilovic EJ, Hillibrand AS, Vaccaro AR, Shapiro IM: Differentiation of mesenchymal...
... migration capacity of human bone marrow mesenchymalstem cells: comparison of chemokine and growth factor chemotactic activities StemCells 2007, 25:1737-1745 24 Segers VF, Van RI, Andries LJ, Lemmens ... transmigration and invasion ofmesenchymalstemcells J Mol Cell Cardiol 2008, 44:1072-1084 30 Estrada R, Li N, Sarojini H, An J, Lee MJ, Wang E: Secretome from mesenchymalstemcells induces ... Serum of control rats was placed in the lower transwell compartment in both cases Bottom: Normalized indices for the migration ofmesenchymalstemcells induced by the serum of control and apneic...
... MesenchymalStemCells In The Treatment Of Acute Myocardial Infarction With the emergence ofstemcells as potential regenerative medicine, attempts to use stemcells to reduce infarct size and ... 2004 Mesenchymalstemcellsand their potential as cardiac therapeutics Circ Res 95, 9–20 Quesenberry, P.J., Aliotta, J.M., 2008 The paradoxical dynamism of marrow stem cells: considerations ofstem ... CHARACTERIZATION OF THE SECRETION OFMESENCHYMALSTEMCELLSAND ITS RELEVANCE TO CARDIOPROTECTION LAI RUENN CHAI (B.Eng (Hons.)), NTU A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY NUS...
... the level ofcells that home to tumors or other sites The tumor homing behavior of MSCs was demonstrated by the mere presence of these cells in the sites of interest and/ or lack of such cells in ... delivery of CX3CL1 to multiple lung tumors by mesenchymalstemcellsStemCells 2007, 25(7):1618-26 12 Komarova S, Kawakami Y, Stoff-Khalili MA, Curiel DT, Pereboeva L: Mesenchymal progenitor cells ... unmodified cells Given complexity of the processes of biodistribution and homing of injected cells, we reasoned that an effect of engineered cell targeting would be more pronounced and better...
... costimulation/B cells Ligand for CD28 and CD152 (CTLA-4)/B cells Growth factor receptor/haemopoietic stemand progenitor cells, mast cells Function unknown/haematopoietic stemcellsand precursors ... and isotype-switching of B cells/ B cells Ligand for CD40/T cells Critical for T and B cell antigen receptor mediated activation/ all haematopoietic cells Ligand for CD28 and CD152 (CTLA-4), T-cell ... marrow-derived mesenchymalstemcellsand neural progenitor cells Haematologica 2003, 88:126-133 Reyes M, Verfaillie CM: Characterization of multipotent adult progenitor cells, a subpopulation of mesenchymal...
... Expression levels of ADAM and adhesion molecules during chondrogenic differentiation ofmesenchymalstemcells (MSCs) The gene-expression (MSCs) profile ofmesenchymalstemcells (MSCs; n = 2) ... No Djouad et al Figure stemcellsof the expression of cell-surface proteins on mesenchymal Modulation(MSCs) stemcells (MSCs) (a) and (b) Change in the protein levels of various surface markers ... expression of these MMPs in MSCs, although the presence of MMP-2 and MMP-3 and absence of MMP-1 and MMP-9 have been reported [30] We confirmed these data and also showed the expression of MMP-28 and...
... Regulation of stemness andstem cell niche ofmesenchymalstem cells: implications in tumorigenesis and metastasis J Cell Physiol 2010, 222:268-277 Ohishi M, Schipani E: Bone marrow mesenchymalstemcells ... cytochemical, and phenotypic features, as well as the capability of differentiating toward mesenchymal lineage cellsandof suppressing CD3+ T-cell proliferation, which are all characteristic of MSCs ... Phenotypic profiles of HPB-AML-I The expression of MSC-related antigens in the HPB-AML-I cell line is shown (A) CD45 expression of round-polygonal HPB-AML-I cells (upper) andof the cells, which...
... ratio of MSCs to cancer cells, nature of tumour cellsand cancer stem cells, integrity of immune system, number ofstem cell passages and site of injection; all can affect the outcome of MSCs ... migration ofmesenchymalstemcells to conditioned medium from tumor cells or bone marrow cellsStemCells 2007, 25:520-528 Reya T, Morrison SJ, Clarke MF, et al: Stem cells, cancer, and cancer stemcells ... disease of dysfunction of the stemcells [32] Stemcellsand tumor cells share similar signaling pathways that regulate self-renewal and differentiation, including the Wnt, Notch, Shh and BMP...
... number ofcells exhibiting typical morphological featuresof apoptotic cell death was determined by scoring 100 cells from 30 different microscopic fields per culture and the number of apoptotic cells ... Characterisation of canine adipose tissue derived mesenchymalstemcells In order to demonstrate that the cells isolated from the canine adipose tissue (Figure 1A) are indeed mesenchymalstemcells (MSCs) ... effects of curcumin inhibit the induction of degradative and inflammatory pathways by IL-1β through revoking activation of caspase-3, production of COX-2, phosphorylation of Iκ-Bα and inhibition of...
... Figure Mesenchymalstemcells used during this study Mesenchymalstemcells used during this study Typical morphological aspects ofmesenchymalstemcells observed through culture flask (A) Mesenchymal ... distribution ofmesenchymalstemcells in vivo Figure Early dynamic distribution ofmesenchymalstemcells in vivo Sequential whole body scintigraphies after infusion of indium-111 labeled mesenchymalstem ... perspective of cellular therapy by intravenous stemcells infusion The participation ofstemcells in several vascular diseases pathogenesis was first proved with haematopoietic stemcells (HSCs)...
... current understanding of etiology and pathogenesis of INTRODUCTION PD, the application of animal models for studying PD, and possible therapeutic application ofstemcells in the treatment of PD will ... degenerated cellsand the transplanted stemcells 4.2 Stem cell transplantation Stemcells are defined by their capability for self-renewal and multipotent differentiation On the basis of these ... have been shown to suppress the function of a broad range of immune cells, including T cells, B cells, NK cellsand antigen-presenting cells (Fig 4) and thus may have therapeutic effect in autoimmune...
... Graft-Versus-Host Disease HaMSC Human Adult MesenchymalStemCells HfMSC Human Fetal MesenchymalStemCells HSC Hematopoietic stemcells HUVEC Human Umbilical Vein Endothelial Cells ICAM-1 Inter-cellular cell ... Introduction 1.1 MesenchymalstemcellsMesenchymalstemcells (MSC), otherwise known as bone marrow stromal cells, was discovered by Friedenstein who noticed that transplantation of bone marrow cells resulted ... full of love i Table of Contents Introduction .1 1.1 Mesenchymalstemcells 1.1.1 MSC of fetal origin 1.1.2 Potential applications of MSC 1.1.3 Mode of...
... x List of Abbreviations and acronyms xii Introduction 1.1 Mesenchymalstemcells (MSC) 1.1.1 Definition ofstemcells 1.1.2 Criteria of being stemcells ... INTRODUCTION 1 Introduction 1.1 Mesenchymalstemcells (MSC) 1.1.1 Definition ofstemcellsStemcells (SC) are defined functionally as cells that have the capacity to self-renew and give rise to differentiated ... mechanisms of hypertrophy and hyperplasia In this in vitro study, we characterize lipidome changes during adipogenesis ofmesenchymalstemcells (MSC) using thin layer chromatography and sensitive...
... differentiate from mesenchymal stromal cells (MSCs) MSCs are multipotent cells that can replicate as undifferentiated cellsand that have the potential to differentiate to lineages ofmesenchymal tissues, ... distribution of mCRY1 and mPER2, and real-time PCR quantification of mCRY1 mRNA after laser irradiation Intracellular distribution of mCRY1 and mPER2 after blue laser irradiation were shown in Figs 1a and ... accumulation of lipid droplets in cells (B) mRNA levels of PPARγ in MSCs 24 hr after laser irradiation (100 mW/cm2) and in non-irradiated cells Samples were normalized to mRps18 The mRNA levels of PPARγ...
... injury Besides HSCs, there also existed another kind ofstemcells called MSCs (Mesenchymal Stem Cells) , they could differentiated into stroma cellsand acted as the “niche” in the micro-environment[24] ... CML and found that these cells could differentiate into malignant blood cellsand phenotypically defined endothelial cells at the single-cell level, suggesting these cells have the properties of ... adhesion of tumor cells to the extracellular matrix, the degradation of the extracellular matrix by the proteinase secreted by the tumor cells, and the transfer and proliferation of tumor cells[ 36] So,...
... analysis and interpretation of data, and drafting or critical revision of the manuscript or both SL contributed to acquisition of data, analysis and interpretation of data, and drafting and critical ... conception and design, acquisition of data, analysis and interpretation of data, and drafting or critical revision of the manuscript or both CK and RWK contributed to study conception and design, ... M: Identification ofmesenchymal progenitor cells in normal and osteoarthritic human articular cartilage Arthritis Rheum 2004, 50:1522-1532 Richter W: Mesenchymalstemcellsand cartilage in situ...
... syntactic, semantic and pragmatic featuresof exaggeration in English and Vietnamese In - To compare and contrast the features mentioned above to clarify the similarities and differences of the two languages ... Exaggeration of Suffering 4.2.5 Exaggeration of Wish 4.2.6 Exaggeration of Quality of People/ Things 4.2.7 Exaggeration of Love 4.2.8 Exaggeration of Strength Exaggeration of Tiredness and Poverty ... feeling the pressure of This study is aimed at finding the similarities and differences in English and Vietnamese in terms of syntactic, semantic and pragmatic features the amount of work they have...
... that binomial and similarities and differences between ECL and VCL in terms of multinomial in both ECL and VCL are formed by nouns This is lexical featuresand syntactic features is of significance ... Part differences of the lexical features between ECL and VCL First of all, there exists a striking similarity between ECL in respect of any infringement of the Chapter I prohibition and VCL is that ... Differences in Syntactic Features use of syntactic discontinuity in ECL and VCL CONCLUSION AND IMPLICATION 5.1 CONCLUSION According to Philip Collins, the current Chairman of the Office of Fair Trading,...
... various featuresof that in expression - Finding out the featuresof pragmatics of the adjective Warm so that individuals have the best understanding and the most effective use of such adjective ... analysis of the semantic feeling, our angry or kindly feelings, feeling of pride or of humility and pragmatic featuresof the adjective Warm in chapter four CHAPTER 2.2.8.4 Politics METHODS AND PROCEDURES ... science of government or governing, especially the governing of a political entity, such as a nation, and the administration and control of its internal and external affairs 3.1 RESEARCH DESIGN AND...