... The effect of atropine on the metabolism of acetylcholine in thecerebralcortex J C Szerb (Halifax, Nova Scotia, Canada) Factorsinfluencingthereleaseofprostaglandins ... enzyme governs the level of ACh The localization of ChAc is therefore synonymous with the site of synthesis of ACh and knowledge of this site gives important information as to the further processes ... soluble in the nuclei cell sap (Sol.); and B, The distribution of radioactivity in the components ofthe P2 fraction Peaks are the same as those described in Fig + on the zonal separation ofthe synaptosomal...
... ouabain-sensitive form when the a subunit of colonic H+/K+-ATPase was expressed together in Xenopus oocytes with the b subunit ofthe H+/ K+-ATPase from toad bladder or with either the b subunit of gastric H+/K+-ATPase ... apical or the basolateral surfaces ofthe epithelial cell membrane Administration of palytoxin on the apical membrane results in the generation of a current (Fig 1A), which is dependent on the presence ... subunits ofthe P2C-type ATPases These possible complexes might induce a particular conformation ofthe palytoxin molecule or ofthe enzyme that favors mutual interaction between the two reactants Therefore,...
... death ofthe cells over the electrode The migration of healthy cells fromthe edge ofthe wounding to the wounding space was tracked Similar to the changes seen with adhesion, over-expression of ... cancer cells and tissues In the course thereof, we have further found that the effect of MDA-7 on prostate cancer cells is dependent on the presence of TGase-4 in the cell Materials and methods ... utility for the gene-based therapy of diverse human cancers The location ofthe MDA-7 gene is closely linked to the Page of IL-10, IL-19, and IL-20 genes within a 195-kb region -the IL-10 family...
... death ofthe cells over the electrode The migration of healthy cells fromthe edge ofthe wounding to the wounding space was tracked Similar to the changes seen with adhesion, over-expression of ... cancer cells and tissues In the course thereof, we have further found that the effect of MDA-7 on prostate cancer cells is dependent on the presence of TGase-4 in the cell Materials and methods ... utility for the gene-based therapy of diverse human cancers The location ofthe MDA-7 gene is closely linked to the Page of IL-10, IL-19, and IL-20 genes within a 195-kb region -the IL-10 family...
... normoxic conditions (Figure 7a) The use of C5-deficient serum prevented the generation ofthe C5b-9 MAC, therefore facilitating investigation ofthe effects of DAF Treatment of HUVEC Available online ... Furthermore, the failure of squalene to influence the response suggested that the mechanism underlying the actions ofthe statins was cholesterol independent Although the effect of statins on ... to the pathogenesis of RA [6] We chose to study vascular EC, as the endothelium is the portal of entry for leukocytes to the rheumatoid synovium and is particularly exposed to deposition of C3...
... plexus ofthe enteric nervous system in the stomach Taurinergic neurons in the muscle layer ofthe gastrointestinal (GI) tract might be involved in motility ofthe GI tract and the function of endocrine ... slices ofthe rat stomach Samples were incubated at 37°C for 30 before the addition of taurine were treated within for the production of cAMP Each column represents the mean ± SEM ofthe percent ... [24-26] The purpose ofthe study was to determine if taurine also regulates gastric acid secretion via GABA receptors in the stomach Localization of taurine in the CNS used enzymatic synthesis of...
... analysis ofthe research hypothesis and the assessment ofthe reliability ofthe research data - Chapter 5: Research discussion and Implications After presenting the results ofthe research in the ... originating fromthe needs of employees to stay in the organization considering the costs of leaving In continuance commitment, the employees consider the disadvantages of leaving the organization ... subset, or some part, of a larger population The definition ofthe sample is of vital importance as the results of an investigation are not trustworthy more than the quality ofthe population or...
... described their own smoking habits as well as those of their dead partners These data were used to determine whether people had ever smoked before 1980, a period of time prior to the onset of their ... prevalence of smoking between male living spouses of women who died of any cause and those spouses of women who died of some other causes other than smoking related causes The prevalence of smoking ... Academy of Medical Sciences who supported the original survey We thank Professor Richard Peto, who gave us great support for the project The cooperation ofthe local government, the thousands of doctors,...
... Effect of KNO3 Spraying on yield and yield Component of rice on Alluvial Soie in Nam Dinh- Spring Rice – 2009 ( Quinal/ha) Number of paricals/m2 Number of grain/pan 1A 1B 12 LS DO5 % of umfiiied ... Effect of KNO3 Spraying on yield and yield Component of rice on Alluvial Soie in Nam Dinh- Summer rice – 2009 ( Quinal/ha) Number of paricals/m2 1A 1B 12 LS DO5 Number of grain/pan % of umfiiied ... 8: Effect of KNO3 Spraying on N and K20 uptake bypaddy Rice on degraded Soil in Bac Giang- 2009 ( Kg N and K20/ha) Treat 1B 12 N Spring Rice K20 Summer Rice N K20 Tab 9: Effect of KNO3 Spraying...
... hypothetical method of FP In further sections women were asked about their knowledge ofthe mechanism of action of specific FP methods and if doctors or providers should explain the details of ... Committee approval for the study was obtained at the University of Navarra Permission to administer the questionnaire was obtained fromthe director of each ofthe centres involved in the study Results ... the questionnaire As a result of pilot testing, the wording of some questions was clarified The centre where the pilot study was carried out was included among the study sites, but the data from...
... created in the electrode compartments and thin tubes were then inserted into these ports to allow gases that are generated fromthe electrolysis of water to escape The other end of these gas tubes ... profiles in the soil fromthe anode to the cathode for the three tests performed on both the kaolin and the glacial till As previously stated, the initial total chromium concentration for all these ... chromium was located in the middle ofthe specimen (Fig 4a) The Cr(VI) profile for kaolin as shown in Fig 5a indicates that the majority ofthe chromium was present in the form of Cr(VI) and this...
... created in the electrode compartments and thin tubes were then inserted into these ports to allow gases that are generated fromthe electrolysis of water to escape The other end of these gas tubes ... profiles in the soil fromthe anode to the cathode for the three tests performed on both the kaolin and the glacial till As previously stated, the initial total chromium concentration for all these ... chromium was located in the middle ofthe specimen (Fig 4a) The Cr(VI) profile for kaolin as shown in Fig 5a indicates that the majority ofthe chromium was present in the form of Cr(VI) and this...
... created in the electrode compartments and thin tubes were then inserted into these ports to allow gases that are generated fromthe electrolysis of water to escape The other end of these gas tubes ... profiles in the soil fromthe anode to the cathode for the three tests performed on both the kaolin and the glacial till As previously stated, the initial total chromium concentration for all these ... chromium was located in the middle ofthe specimen (Fig 4a) The Cr(VI) profile for kaolin as shown in Fig 5a indicates that the majority ofthe chromium was present in the form of Cr(VI) and this...
... Following the baseline scores, the frequency of exacerbations significantly accounted for the changes in the Mastery ofthe CRQ (R2 = 0.03) and the Symptoms ofthe SGRQ (R2 = 0.05), and the RV/TLC ... in the Mastery ofthe CRQ and Symptoms ofthe SGRQ, independent of their baseline scores, and logistic regression analyses confirmed a statistically significant effect ofthe exacerbations on the ... Mastery), the total scores ofthe CRQ and the Symptoms scores ofthe SGRQ Subjects with exacerbations showed a clinically significant decline (>4 units) during the 6-month study period in their SGRQ...
... Following the baseline scores, the frequency of exacerbations significantly accounted for the changes in the Mastery ofthe CRQ (R2 = 0.03) and the Symptoms ofthe SGRQ (R2 = 0.05), and the RV/TLC ... in the Mastery ofthe CRQ and Symptoms ofthe SGRQ, independent of their baseline scores, and logistic regression analyses confirmed a statistically significant effect ofthe exacerbations on the ... Mastery), the total scores ofthe CRQ and the Symptoms scores ofthe SGRQ Subjects with exacerbations showed a clinically significant decline (>4 units) during the 6-month study period in their SGRQ...
... concentration of acrylamide (2,500 and 5,000 µg/plate) in the presence of S9 mixture, which suggests the formation of mutagenically active metabolite(s) of acrylamide Chromosomal aberration The results of ... presence or absence of S9 mixture Moreover, the cells treated with 10 or 50 mM of acrylamide further increased the frequencies in the presence or absence of S9 mixture Overall, the chromosomal aberration ... mg/kg/day of acrylamide showed histopathological changes in the seminiferous tubules (Fig 5B) There were thickening and multiple layering ofthe tubular endothelium, degeneration of germ cells, and the...
... phase IIIb study (the Adalimumab R251 Research in Active RA [ReAct] study [20]) The study was approved by the ethical committee ofthe Ospedale L Sacco (Milan, Italy) The mean age ofthe patients ... defence capacity On the other hand, the inhibitory activity ofthe mAb on CD69 membrane expression on neutrophils indicates that these cells are among the possible targets of anti-TNF-α activity ... Briefly, 200 µl ofthe cell suspension, containing 2.5 × 106 neutrophils/ml in RPMI1640 + 0.4% BSA were layered on top ofthe filter, and the lower compartment was filled with 200 µl ofthe chemotactic...
... number ofthe cells migrating to the bottom side ofthe filter was counted and the chemotactic index was calculated as the number of cells migrating toward the test sample divided by the number of ... to the cartilage and bone destruction of RA These findings, together with a better understanding ofthe relationship between CD147, CyPA and RA and ofthe possible mechanism and regulation ofthe ... filter and attached to the lower side ofthe filter (× 150) In the co-culture of undifferentiated THP-1 cells and HFC, the number of cells was increased compared with the cultures of THP-1 cells or...
... meta-analysis The overall pooled analysis included the mean changes ofthe FVC and the DLCO after 12 months of therapy obtained fromthe observational studies and fromthe CYC experimental arm ofthe randomized ... needed to better understand the role of CYC in the care of these patients In our meta-analysis, two ofthe three greatest mean differences ofthe FVC after 12 months of therapy were achieved in ... improvement of pulmonary function Since none ofthe patients included in these studies were selected on the basis of progression of ILD or the time fromthe SSc-related ILD diagnosis, further randomized...
... participated in the design ofthe study, performing ofthe experiments and helping draft the manuscript OAM participated in the performing the experiment and revised the manuscript and constructed the figures ... started by the addition of NADH, incubated at 30°C and stopped by the addition of ml of glacial acetic acid The absorbance ofthe chromogen formed was measured at 560 nm One unit of SOD activity ... attenuates the oxidative injury ofthe muscle cells but also reduces the formation of edema in these cells This may be due to the anti-inflammatory effect of α-TOL by inhibiting PGE2 production [43] The...