... studies have documented an age-dependent decline in serum 25hydroxyvitamin Dand 1,25-dihydroxyvitamin D, and this age-related decline steadily worsened with institutional placement, decreasing ... D2 andvitamin D3 release from the skin after UVB exposure A recent randomised, placebo-controlled, double-blinded study of healthy adults aged 18-84 years demonstrated that a daily 25 àg dose ... 5,6-trans -vitamin D3 Cholesterol Vitamin D3 Vitamin D3 Basal membrane Dermis DBP -D3 DBP DBP DBP -D3 DBP -D3 DBP Figure 4.2 - Photochemical synthesis of vitamin D3 in human skin (from Bodo Lehmann,...
... they would have reduced skin production of vitaminD due to higher melanin content, coupled with reduced sunlight exposure Second, although milk in Ireland is fortified with vitamin D, both patients ... features in vitaminD deficiency related myopathy are the proximal distribution, the waddling gait, and pain and discomfort due to muscular effort Both cases demonstrated these findings clinically ... belong to high risk groups A correct diagnosis can help avoid prolonged and needless investigations for these patients, as the condition is reversible and easily treated with vitaminDand calcium...
... respective signal transduction pathways Several interactions between the vitaminDand oestrogen endocrine system have been described 1,25-Dihydroxyvitamin D3 (1,25-(OH) 2D3 ) and 17β-estradiol (E2) have ... associations between DDH andvitaminDand oestrogen receptor polymorphisms Further work with a larger series of patients and possibly more candidate gene polymorphisms may well shed more light on ... contributions BK and CD performed the molecular assays CD and CHWJ were involved in the conceptualisation of the study as well as defining the radiographic measurement methods RCS and AAF were involved in...
... acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid and α-linolenic acid e Sum of arachidonic and linoleic acids b Age Dietary intake of omega-3, omega-6 fatty acids, vitaminDandrisk ... intake and dietary intake of vitamin B12, alcohol and dietary intake of fat other than eicosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid e Sum of arachidonic and linoleic acids ... low-fat dairy products and margarines are fortified with vitaminD Otherwise the dietary intake of vitaminD would be lower Furthermore, men were not included in the study and there is gender difference...
... Occupational Safety and Health (NIOSH) Authors’ contributions JB, MK, AW, AR, IL and MG contributed to the concept and design of the study HA-Z and KS co-ordinated the informed consent and referral process ... supervised data collection and, along with RD, assessed exposure values RP constructed the analysis files, designed the statistical models and performed the analysis RP, MK, JB, MB, AW and MG interpreted ... Cancer and developmental exposure to endocrine disrupters Environ Health Perspect 2003, 111:389–394 12 Fenton SE: Endocrine-disrupting compounds and mammary gland development: early exposureand later...
... isolated and expanded, and the expression of PTEN was examined by western blotting (C) Colony was treated with VD3, and apoptosis was evaluated (D) *P < 0.05, **P < 0.01, (n = 3) participated in ... in the VD3-induced apoptosis in gastric cancer cells indicated that vitaminD induced PTEN expression through binding of VDR to the PTEN promoter VitaminD upregulated PTEN through VDR VDR synergistically ... (2000) VitaminDand prostate cancer Endocrinology 141, 5–9 Holick MF (2004) Sunlight andvitaminD for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease...
... contributed to study design and concept and writing and editing of the manuscript VT: contributed to the study design and concept, writing and editing of the manuscript and provided financial ... supervised in study design, and was involved in drafting the manuscript VT carried out the initial conception and design of the study, supervised and assisted in laboratory techniques, and was involved ... analysis HB provided general supervision and was involved in drafting the manuscript GM provided samples, supervised in study design, and was involved in drafting the manuscript TZ provided samples,...
... blinded, within-subject randomised, active- and vehicle-controlled, repeated dose study, conducted at CPCAD, Nice, France No topical treatment had been applied for four weeks prior to admission and ... derived from the method described by KJ Dumas and JR Scholtz [2] For each subject, six test sites of 2-cm diameter were selected on predetermined lesions, and a circular adhesive device was placed ... animals were bled and sacrificed The serum levels of calcipotriol and BDP were analyzed and determined to be below the detection limit (data not shown) Discussion The objective of this study was to...
... the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analyses Study concept and design: CA and OB Acquisition of data: CA and OB Analysis and ... Jackson RD et al 2006 [13] - Randomized trial, controlled, double blinds - Randomized trial, controlled, double blinds - Mean follow-up 10 months - Vertebral fracture and long bone, and fall - ... supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials BMJ 2009, 339:b3692 Avenell A, Gillespie WJ, Gillespie LD, O’Connell D: VitaminDandvitaminD analogues...
... polymorphisms VDR, vitaminD receptor Table Associations between the combined Apa I, Bsm I, and Fok I VDR polymorphisms and severe chronic periodontitis risk † Adjusted for age † † Adjusted for age, ... present, and prevalence of diabetes VDR, vitaminD receptor; OR, odds ratio; CI, confidence interval DISCUSSION We examined the relationship between ApaI, BsmI, and FokI VDR polymorphisms and severe ... between VDR polymorphisms and susceptibility and outcome have been indicated in prostate, lung, and colon cancers [19-21] Zou et al [20] suggested that VDR polymorphisms of Cdx2, FokI, and BsmI...
... which included daily oral doses of vitamin D3 between 500 IU and 1000 ID per day VitaminD is now even sold over the counter Moreover, it is included in most commercial baby food products although ... and this was endorsed by many physicians" [9] This tradition was restricted to the coasts of England, Holland, and France [10] Industrialized cod liver oil production (as the sole source of vitamin ... irradiated ergosterin, was introduced into the market by E Merck AG, who produced between and kg of vitamin D2 per year Production increased after 1938 up to 40 kg but ceased in 1945 [19] and was...
... association was observed between individual VDR gene polymorphisms and the overall odds of hand OA However, the VDR aa genotype posed an almost doubled odds of symmetrical hand OA (OR = 1.93, 95% ... participated in the evaluation of reliability of radiographs' readings HR conceived of the study and participated in its design PLA conceived of the study and participated in its design and coordination ... Ann Rheum Dis 1989, 48:271-280 53 Sowers M, Lachance L, Hochberg M, Jamadar D: Radiographically defined osteoarthritis of the hand and knee in young and middle-aged African American and Caucasian...
... sodium phosphate, pH7.4 and 0.9% sodium chloride), the second antibody conjugated with horseradish peroxidase was added to incubate for one hour The ECL detection system (Millipore) was used and ... biotin-conjugated secondary antibody (2 μg/mL) was added to incubate at 300 rpm for 30 Finally 50 μL of streptavidin-Phycoerythrin was added to each well and mixed at 300 rpm for 10 After drying up and washing, ... presented in eight gels The expressional trends of A2M (D) , VDBP (E) and ApoAI (F) were calculated with DeCyder 6.5 software A2M is an up-regulated protein; VDBP and ApoAI are down-regulated proteins...
... performed using a standard automatic analyzer Height, weight, systolic blood pressure, and diastolic blood pressure were measured according to standard protocols Hypertension was defined as (1) ... and the statistical significance level was defined as p < 0.05 Results Conventional risk factors and carotid atherosclerosis Table presents the frequency distribution and the ageand gender-adjusted ... ingested arsenic exposure with the development of cardiovascular disease [3-5] Epidemiological studies carried out in Taiwan identified several vascular disorders caused by long-term exposure...
... polymorphisms of VitD receptor (VDR) and VitD binding protein (DBP) have been identified that modulate the development of tuberculosis [96] The genotype tt (detected by Taq I digestion) is associated ... inclusion and again at and months after start of treatment Reduction in TBscore and sputum smear conversion rates did not differ among VitD and placebo treated patients Taken those data together ... Sandford AJ: VitaminD binding protein variants and the risk of COPD Am J Respir Crit Care Med 1998, 157:957-961 78 Taes YE, Goemaere S, Huang G, Van PI, De BD, Verhasselt B, et al: Vitamin D...
... acquired funding for the SAGE and CAPPS studies TJH and CL conceived and acquired funding for the SLSJ study TJH also provided general supervision of the research group All authors read and approved ... (encoded by the CYP24A1 locus) In vitaminD target cells, 1α,25-(OH)2 D3 translocates to the nucleus and binds to the vitaminD receptor (VDR) The ligand/receptor complex binds vitaminD response ... participated in the conception and coordination of the BHS BAR and STW participated in the conception and coordination of CAMP ALK participated in the coordination of the SAGE study AB conceived and acquired...
... report J.A did the clinical survey, C.B did the SNP analysis, M.B built serum and DNA bank and did the vitaminD assays together with E.A who supervised also laboratory work and did functional ... SNPs indicated by ¶ were used to build haplotypes candidate genes was rather subjective, it turned out that some of the tested candidate genes are associated with both allergy andvitaminD metabolites ... tamin D3 and 25-hydroxyvitamin D3 in the blood and tissues of the 25-hydroxyvitamin D- 24-hydroxylase (Cyp24a1) null mouse Endocrinology 2005, 146:825-834 Ren S, Nguyen L, Wu S, Encinas C, Adams...
... with dietetic and anthropometric variables Obesity 2009, 17:778-782 McGill A-T, Stewart JM, Lithander FE, Strik CM, Poppitt SD: Relationships of low serum vitamin D3 with anthropometry and markers ... Immunomodulatory effects of vitaminD in multiple sclerosis Brain 2009, 132:1146-1160 Rodríguez-Rodríguez E, Navia B, López-Sobaler AM, Ortega RM: VitaminD in overweight/obese women and its relationship ... CA, Samuel MC, Rosenberg J, Talarico J, Hatch D; California Pandemic (H1N1) Working Group: Factors associated with death or hospitalization due to pandemic 2009 influenza A(H1N1) infection in California...
... Tây D ơng có xương đóng hộp Cá mòi Thái Bình D ơng có xương đóng hộp Cá hồi có xương đóng hộp Gạo sữa đậu nành có tăng cường thêm chất canxi Nước cam có tăng cường thêm chất canxi sinh tố D Sữa ... biến loại để trét Phô mai, chế biến thành lát mỏng Phô mai làm từ sữa gạn kem, 2% Bánh pút-đinh (pudding) sữa trứng Sữa chua (yogurt), nguyên chất Sữa chua, có trái đáy hủ Sữa chua đông lạnh, loại ... xanh (broccoli) Cam Mật đường đen (Blackstrap molasses) Cá khô, cá ốt-me (smelt) Bông hoa hiên (daylily flower) Bánh đậu tương lên men, nấu chín Cải Fat choy (tóc tiên), khô Đậu hủ miếng to, nửa...