evolving approaches to patients with advanced differentiated thyroid cancer
báo cáo hóa học:" Neuronal transcription factor Brn-3a(l) is over expressed in high-grade ovarian carcinomas and tumor cells from ascites of patients with advanced-stage ovarian cancer" ppt
Ngày tải lên :
20/06/2014, 07:20
... it fails to get rid of any residual microscopic
disease. As a consequence, within few months these
patients return with recurrent cancer[ 1]. In most cases,
patients present themselves with multiple ... thirty years with a five-year survival of only
30% [1,2]. The majority of patients are diagnosed with
Stage 3 or 4 d isease, when the cancer has spread from
the pelvis to the peritoneal cavity ... contrast to almost all other can-
cers, ovarian cancer typically does not spread through
the b loodstream. Instead, tumor growth is often limited
to the abdominal (peritoneal) cavity, even in advanced
cases....
- 12
- 267
- 0
Báo cáo hóa học: "Anti-CDC25B autoantibody predicts poor prognosis in patients with advanced esophageal squamous cell carcinoma" pptx
Ngày tải lên :
18/06/2014, 16:20
... that CDC25B
autoantibodies were more prevalent in sera from
patients with ad vanced ESCC than in sera from patients
with early stage disease (P < 0.001) and that in the
patients with clinical ... properly cited.
than in patients with early stage disease [22,38]. Over-
expression of CDC25B in advanced ESCC may thus lead
to high production of CDC25B-Abs in patients with
advanced tumors. These ... adjuvant chemoradiation for patients with
ESCC, the five-year survival rate of patients with
advanced ESCC is still poor [2]. This poor survival rate
is largely due to the lack of serological...
- 8
- 409
- 0
Báo cáo hóa học: "Multicenter phase II study of matured dendritic cells pulsed with melanoma cell line lysates in patients with advanced melanoma" potx
Ngày tải lên :
18/06/2014, 16:20
... vaccine and
immunotherapy approaches for cancer. There have been
two large randomized trials suggesting that adjuvant
therapy with cancer vaccines may be detrimental to
patients with surgically treated ... of
therapeutic vaccination with dendritic cells (DC) in patients with metastatic melanoma. The efficacy of this
approach in patients with favorable prognosis metastatic melanoma limited to the skin, subcutaneous ... t hey are known to trigger CD8 cytotoxic responses
in vivo [5,6]. An initial phase I/II study was performed
pulsing IDD-3 with just one melanoma cell line lysate
(M17) together with hepatitis...
- 11
- 459
- 0
báo cáo hóa học: " The AMC Linear Disability Score (ALDS): a cross-sectional study with a new generic instrument to measure disability applied to patients with peripheral arterial disease" potx
Ngày tải lên :
18/06/2014, 19:20
... investigated by
comparing the ALDS between patients with IC and
patients with CLI, with ALDS scores to be expected higher
in patients with IC than in patients with CLI.
The VascuQol was used as benchmark ... and 3.1 in patients with CLI)
and the VascuQol domain Activity (4.0 in patients with
claudication versus 2.4 in patients with CLI). The effect
size values for the ALDS and the VascuQol total and ... was
significantly higher in patients with claudication (ALDS
score 80) than in patients with CLI (ALDS score 64). Sim-
ilar results were obtained for the VascuQol total score (4.5
in patients with claudication...
- 8
- 386
- 0
Báo cáo hóa học: " Caregiver assessment of patients with advanced cancer: concordance with patients, effect of burden and positivity" ppt
Ngày tải lên :
18/06/2014, 22:20
... Clinicians and researchers often have to rely on information from caregivers to
assess patients with advanced cancer. This study aims to assess the validity (using patients& apos;
assessment as the ... median total POS score than patients.
Table 1: Demographic and clinical characteristics statistics for advanced cancer patients and their caregivers
Variable Patient n (%)* Caregiver n (%)*
Total ... and Quality of Life Outcomes
Open Access
Research
Caregiver assessment of patients with advanced cancer:
concordance with patients, effect of burden and positivity
Irene J Higginson* and Wei Gao
Address:...
- 8
- 456
- 1
báo cáo hóa học:" The AMC Linear Disability Score (ALDS): a cross-sectional study with a new generic instrument to measure disability applied to patients with peripheral arterial diseas" potx
Ngày tải lên :
20/06/2014, 16:20
... investigated by
comparing the ALDS between patients with IC and
patients with CLI, with ALDS scores to be expected higher
in patients with IC than in patients with CLI.
The VascuQol was used as benchmark ... rest
(in patients with CLI)
0.35 (0-0.59)
Decrease ABI after exercise
(in patients with IC)
a
0.28 (0.09-0.55)
Toe pressure mmHg
(in patients with CLI)
19 (0-67)
ALDS 71 (± 17)
VascuQol total 3.7 ... was
significantly higher in patients with claudication (ALDS
score 80) than in patients with CLI (ALDS score 64). Sim-
ilar results were obtained for the VascuQol total score (4.5
in patients with claudication...
- 8
- 335
- 0
báo cáo khoa học: "Recurrent differentiated thyroid cancer: to cut or burn" pot
Ngày tải lên :
09/08/2014, 02:20
... older patients without
extrathyroidal localization, either out of the thyroidal
capsule or at distance or without extrathyroidal localiza-
tion or out of the thyroidal capsule and patients with ... another important risk factor. In Mayo Clinic study
5% of patients with intracapsu lar cancer relapsed within
20 years against 15% relapse in patients with extracapsu-
lar cancer. In the Lahey Clinic ... multifocality does not
appear to be a significant risk factor in the development
of local recurrence in patients who undergo total thyroi-
dectomy (TT) or near total thyroidectomy (NTT) [23].
When LR...
- 4
- 305
- 0
Báo cáo khoa học: "Combination therapy with docetaxel and S-1 as a first-line treatment in patients with advanced or recurrent gastric cancer: a retrospective analysis" docx
Ngày tải lên :
09/08/2014, 03:21
... treatment
for patients with advanced or recurrent gastric cancer
and to analyze prognostic factors in these patients.
Patients and methods
Patients
The subjects of this study were 86 patients treated
between ... (S-
1 alone). In total, 638 patients were enrolled (the original
Table 3: Hematologic and non-hematologic toxicities
Grade of toxicities % of Grade
Toxicity 12343 or 4
Hematologic
toxicities
Leukopenia ... with docetaxel and S-1 in patients with advanced or recurrent gastric cancer.
Methods: Eighty-six patients with advanced or recurrent gastric cancer were enrolled. Patients received docetaxel,...
- 7
- 407
- 0
Báo cáo khoa học: "Outcomes of resection and non-resection strategies in management of patients with advanced colorectal cancer" doc
Ngày tải lên :
09/08/2014, 04:21
... of advanced CRC in an
unselected, consecutive series of patients presenting with
newly diagnosed disease. It reviews and compares the out-
comes of patients with advanced bowel cancer treated
with ... treatment in the
majority of patients with advanced disease is palliation
with a view to optimise quality of life (QoL) and survival
time[4].
Patients diagnosed with Stage IV disease CRC present ... informed consent, for patients with
stage IV colorectal cancer, as survival is comparable to that
of resection and without the burden of a stoma. Further
studies are required to assess the impact...
- 7
- 327
- 0
Báo cáo khoa học: "A phase II randomized trial comparing radiotherapy with concurrent weekly cisplatin or weekly paclitaxel in patients with advanced cervical cancer" potx
Ngày tải lên :
09/08/2014, 09:20
... 15 patients) concurrently
with radiotherapy.
Chemotherapy
Patients were randomized into two groups: group 1 trea-
ted with weekly cisplatin and group 2 treated with
weekly paclitaxel. Group I patients ... comparing
radiotherapy with concurrent weekly cisplatin or weekly paclitaxel in
patients with advanced cervical cancer. Radiation Oncology 2010 5:84.
Submit your next manuscript to BioMed Central
and ... treatment response, overall
survival, and time to relapse. Time to relapse was
defined from the date of entry into the study to the date
of recurrence. Patients with progressive disease who
never achieved...
- 8
- 300
- 0
Báo cáo hóa học: " Mass spectrometry-based analysis of therapy-related changes in serum proteome patterns of patients with early-stage breast cancer" pot
Ngày tải lên :
18/06/2014, 16:20
... observed
among patients differing in expression of progesterone/
estrogen receptors, which most apparently corresponded
to ongoing anti-estrogen treatment of patients with high
expression of these receptors. ... previously to have
potential in the detection and classification of breast cancer. Here we aimed to identify changes in serum proteome
patterns related to therapy of breast cancer patients.
Methods: ... subgroup of patients treated with adjuvant therapy,
but not in the subgroup subjected only to surgery. This suggests that the observed changes reflect overall responses of
the patients to the toxic...
- 11
- 391
- 0
báo cáo hóa học:"Decreased health-related quality of life in disease-free survivors of differentiated thyroid cancer in Korea" potx
Ngày tải lên :
20/06/2014, 16:20
... (2.5%) had follicular thyroid carci-
noma. A total thyroidectomy was performed in 89.9%
(284/316) of the patients, and 10.1% (32/316) had a sub-
total thyroidectomy or lobectomy. Based on TNM sta-
ging, ... non-toxic multi-nodular goiter and
found a decreased HRQOL in the DTC patients that
was not related to blood TSH levels [7].
In our stud y, 89.9% of the patients underwent total
thyroidectomy ... generalizing this study’ s results to all DTC
patients. Further investigation with a larger number of
Table 5 HRQOL according to the mode of treatment of thyroid cancer
Variables Surgery
alone
(n...
- 10
- 311
- 0
báo cáo khoa học: "Prognostic factors in patients with node-negative gastric cancer: an Indian experience" pdf
Ngày tải lên :
09/08/2014, 01:24
... proportion of patients with early gastric
cancer, we wished to study the factors influencing the
survival in Indian patients with node-negative gastric
cancer, most of whom have advanced gastric cancer.
This ... prognostic factor in gastric cancer. There are
subgroups of patients with different prognosis even in node-negative patients of gastric cancer. The aim of this
study is to analyze the factors influencing ... Yamagishi H:
Efficacy of prophylactic extended lymphadenectomy with gastrectomy
for patients with node-negative advanced gastric carcinoma.
Hepatogastroenterology 2008, 55:755-759.
26. Giuliani A,...
- 6
- 365
- 0
