evidence from liver transplantation importance of the graft volume
Báo cáo y học: " A novel approach for prediction of tacrolimus blood concentration in liver transplantation patients in the intensive care unit through support vector regression" doc
... USA) A profound overview of the underlying theory and the SVM algorithm itself is given by Guyon and Elisseeff [33] In the case of SVR [29], the goal is to find a function that predicts the target ... was kept separate is then used to verify the data model The reported accuracy is the total of those measured in each of the five iterations, thus covering the total amount of available data Variable ... contributed to the statistical analysis and the drafting of the manuscript SVL performed data transformation, wrote part of the SVM algorithm, and contributed to the drafting of the manuscript...
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Tài liệu Báo cáo Y học: Importance of the amino-acid composition of the shutter region of plasminogen activator inhibitor-1 for its transitions to latent and substrate forms pdf
... 74% of the cases; residue 186 an Asn in 87% of the cases; and residue 334 a His in 80% of the cases [3] In addition, residue 54 is a Pro in 89% of the cases The importance of the identity of the ... we reach the conclusion that the substitutions in the shutter region affect the rate of latency transition by affecting the rate of passage of the RCL through the gate region Based on the aminoacid ... wild-type, and the use of this pH therefore allowed optimization of the difference in the effect of vitronectin on wild-type and the unstable variants The presence of vitronectin during the incubations...
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Báo cáo khoa học: Molecular basis of perinatal hypophosphatasia with tissue-nonspecific alkaline phosphatase bearing a conservative replacement of valine by alanine at position 406 Structural importance of the crown domain potx
... value of the mutant TNSALP was less than one-tenth of the Kcat ⁄ Km value of the soluble form of the wild-type enzyme, indicating that the replacement of valine with alanine at position 406 in the ... of TNSALP In support of our hypothesis, the cysteine residue at position 433 in one subunit of TNSALP (R433C) becomes crosslinked to the counterpart of the other subunit [29], implying that the ... containing the SV40 early promoter [11] Shortage of a precursor of GPI in the endoplasmic reticulum may be one of the reasons why a small but significant fraction of the wild-type TNSALP forms the aggregate...
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Báo cáo Y học: Propionate CoA-transferase from Clostridium propionicum Cloning of the gene and identi®cation of glutamate 324 at the active site pdf
... respectively) of the b subunit of glutaconate CoA-transferase protrude into a cleft on the surface of the a subunit and are involved in mediation of subunit interactions Therefore, the lack of this ... of the peptidyl amide nitrogen of the glutamyl residue to the thiol ester carbonyl, releases the thiol forming a protein-bound 4-oxoproline residue The peptide bond between this residue and the ... ions in MALDI-TOFMS measurements, indicating a molecular mass of 56 607 60 Da The molecular mass of the transferase increased by 750 Da when the enzyme was incubated in the presence of 100 lM propionyl-CoA...
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ECONOMIC IMPORTANCE OF THE PLANTATION SECTOR IN KERALA pdf
... significance of this sector Table 4.5 shows the details of the Centre-State break up of the various I taxes from the Plantation sector to the State Govenunent ,A varlety of taxes ;inti duties to the Central ... compared to other agncultural workers, is that they earn a regular income to support the family They are one of the most organrsed labour force of the economy Moreover, the mechanisation of the worlts ... whlch they recelved a cornmisslon from the workers they brought A distindt feature of recruitment was that the unit of recruitment was the family and not the individual Though the system of recruitn~ent...
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Báo cáo khoa học: Importance of the gating segment in the substrate-recognition loop of pyranose 2-oxidase pptx
... the effect of these mutations on the P2O-catalysed reaction; accordingly, one of the substrates of P2O (either the electron acceptor or donor) was fixed, with the other one being varied, and the ... Comparison of the active-site volumes To determine whether there are changes in the volume of the active site as a result of mutations that may explain the ability to accommodate substrates other than ... sodium dithionite in the absence of oxygen, and recording of the spectra of the reduced states was repeated To investigate the effect of the mutations on the flavinylation state of the P2O variants,...
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Báo cáo khoa học: Structural determinants of protein stabilization by solutes The importance of the hairpin loop in rubredoxins pdf
... (n) The lower plots show the difference of the coefficients in the presence of (B) DGP or (C) MG relative to water The points on the horizontal axis cover the entire sequence of residues of the ... for some of these residues (Fig 3) In particular, the exposure of the residues that comprise the lower part (relative to the orientation depicted in Fig 2) of the hydrophobic core of the native ... series of mutants of RdDg was constructed to investigate the importance of these mutations on the degree of stabilization rendered by solutes It is well-documented that the thermal denaturation of...
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o cáo hóa học:" Summit on cell therapy for cancer: The importance of the interaction of multiple disciplines to advance clinical therapy" ppt
... to the advancement of adoptive cellular therapy of cancer, but this and most other areas of clinical therapy will benefit from the cross-fertilization that results from the interactions with other ... biology and the translation of advances in these fields from the research laboratory to the clinic The continued development of this field is dependent on the exchange of ideas across these diverse ... biology and the translation of advances in these fields from the research laboratory to the clinic The continued development of this field is dependent on the exchange of ideas across these diverse...
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báo cáo khoa học: "A Review of Duodenal Metastases from Squamous Cell Carcinoma of the Cervix Presenting as an Upper Gastrointestinal Bleed" potx
... confirmation of the exact nature of this neoplastic lesion, the patient was investigated with computed tomography (CT) scans as part of pre-surgical workup The CT scans confirmed the presence of large soft-tissue ... SCANS of the Abdomen 1a: CT scan demonstrates the presence of a soft tissue mass (*) impinging on the duodenum 1b: CT scan demonstrates the presence of an extensive, abnormal retroperitoneal soft-tissue ... upper-gastrointestinal bleeding two years after the diagnosis of SCC of the cervix At esophagogastroduodenoscopy, there was a stricture in the second part of the duodenum which was biopsied for a suspected...
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Báo cáo khoa học: "Pulmonary lymphangitic carcinomatosis from squamous cell carcinoma of the cervix" pptx
... consent of the patient or her next of kin for publication could not be obtained A copy of the waiver of consent from the Research Ethics Office, University of Saskatchewan, has been submitted to the ... approved the final manuscript Page of Consent/Competing interests Publication of these cases without patients consent was exempted by the Research ethics board of University of Saskatchewan as the ... through the lymphatic system is hypothesized to occur in one of two ways: either through hematogenous spread to the interstitial space followed by the lymphatics or in a retrograde manner from the...
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Báo cáo khoa học: "Safety margin in irradiation of colorectal liver metastases: assessment of the control dose of micrometastases" potx
... with coverage of 87.5% for the distance of 21 was 15.4 Gy: 87.5% of the doses in the isocenters of the micrometastases with a dis- Figure Boxplot of the dose at the 3D isocenter of each micrometastasis ... coverage of 87.5% and 75% 87.5% means that 87.5% of the data (dose measured in the center of the micrometastasis) are below the upper limit of the tolerance interval (with a confidence of 97.5%) The ... confirmation of tumor regrowth Page of c) The 3D isocenter of the new lesion was ≤ 23.5 mm from the initial margin of the metastasis before brachytherapy (adapted from histopathological studies by...
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Báo cáo y học: "The biological and clinical importance of the ‘new generation’ cytokines in rheumatic diseases" pot
... increased in the paws of mice with CIA during the inflammatory early phase of the disease Administration of neutralising anti-ST2 antibodies reduced the severity of CIA and the production of interferon-gamma ... define the biologic role and therefore therapeutic utility of this cytokine in pathology A further intriguing approach is to modulate the synthesis and release of IL-18 Whereas the inhibition of ... alone or via off-target effects on other members of the JAK signalling pathways or beyond Moreover, the toxicity profile of these agents used either alone or in combination with other conventional...
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báo cáo khoa học: " Characterization of cp3 reveals a new bri1 allele, bri1-120, and the importance of the LRR domain of BRI1 mediating BR signaling" doc
... BKI1 to the C-terminal portion of BRI1 In the presence of BR, BKI1 is released by the direct binding of BR to the 70-amino acid island region in the extracellular domain of BRI1 [7] Then, BRI1 ... bri1 A The schematic protein structure of BRI1 is shown and the mutation site of bri1-120/cp3 is marked in the 13th LRR of the extracellular domain of BRI1 B Overexpression of BRI1 rescued the cp3 ... provide any clues regarding the functional importance of the LRR domains of BRI1 In this study, we analyzed the BR-related phenotypes of cp3 grown from the CS48 seeds obtained from ABRC to have more...
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Báo cáo y học: "Typhoid ulcer causing life-threatening bleeding from Dieulafoy''''s lesion of the ileum in a seven-year-old child: a case report" doc
... hemorrhage from these ulcers the condition [7,8] In a large series of 89 patients with DLs, the lesions were extragastric in a third of the cases The duodenum was the most common location (18%) of extragastric ... ulceration of the ileal mucosa with characteristic dilated aberrant submucosal vessel that erodes the overlying epithelium In the absence of a primary ulcer, Dieulafoy's lesion was seen in the terminal ... (18%) of extragastric DLs, followed by the colon (10%), jejunum (2%) and the esophagus (2%) [8] The pathology of the lesion is essentially the same throughout the gastrointestinal tract and is caused...
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Báo cáo y học: " Low tidal volume, high respiratory rate and auto-PEEP: the importance of the basic" ppt
... degree of wisdom As stated by Tobin [6], “… there is no substitute for the clinician’s standing by the ventilator, making necessary adjustments, and monitoring the effects of such adjustments The ... well known, and the clinician should be aware of them and monitor them In the presence of a known haemodynamic impairment, such as a decreased cardiac index (as was observed in the study by VieillardBaron ... physiology, which has taught us almost all of the major principles that we need Every so often some of these principles are rediscovered, and this strengthens their role After all, it is no bad thing...
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Báo cáo y học: "Bench-to-bedside review: The importance of the precision of the reference technique in method comparison studies – with specific reference to the measurement of cardiac output" ppsx
... mean that the physiological status of the patient has changed The error of the measuring technique is directly related to the magnitude of the least significant change (LSC) The LSC is the minimum ... assessing the combined error of the two This has been studied extensively with ITD and the variance can range from 5% to 15% depending on the technique used The main limitation of this ± 30% cutoff, therefore, ... measurement of cardiac output They compared these against ITD cardiac output from the pulmonary artery catheter, which they described as having a precision of ± 20% They suggested that, in order for the...
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Báo cáo y học: "The Importance of the Discourse on the Method" doc
... http://www.capmh.com/content/4/1/2 Page of of the U.S Department of Health and Human Services, the National Institutes of Health, or the National Institute of Mental Health Received: 10 December ... Vitiello: The Importance of the Discourse on the Method Child and Adolescent Psychiatry and Mental Health 2010 4:2 Publish with Bio Med Central and every scientist can read your work free of charge ... be the most significant development for disseminating the results of biomedical researc h in our lifetime." Sir Paul Nurse, Cancer Research UK Your research papers will be: available free of...
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Báo cáo y học: " Arterial embolization of an extrapleural hematoma from a dislocated fracture of the lumbar spine: a case report" potx
... for the treatment of intractable bleeding following burst or compression fractures of the spine However, if extravasation of the contrast medium from the intercostal and lumbar arteries into the ... spine The right intercostal and lumber arteries extend over the vertebrae after branching from the aorta Therefore, we think that the right 12th intercostal artery and the first lumbar artery of ... http://www.sjtrem.com/content/17/1/27 the patient A copy of the consent form is available for review from the Editor-in-Chief of this journal Competing interests The authors declare that they have no competing...
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LUẬN MẪU LỚP 12 The importance of the newspaper
... a profound influence on the minds of its reader Therefore, when some news is reported wrongly either by mistake or design, it may cause a lot of harm On the other hand, if the policy of the newspaper ... us to see and hear some of the famous leaders of the world We are also able to see some of the great events of the day In addition, we can get news from all parts of the world, and listen to ... to promote the welfare of the people, it could a lot of good For example, it could exercise its influence to persuade the government of a country to many things for the benefit of the people...
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A study on lexical cohesive devices from some reading texts of the course book English for Business Study and pedagogical implications for teaching English for third year students at Trade Union University
... and data analysis The subjects of the study The six texts studied in this thesis are extracted from six units of the course book EBS which are included in the ESP course level 2, the course designed ... limitations of the study as well as some recommendations for further research Major findings of the research The aims of the study include investigating the kinds of lexical cohesive device and their ... frequency of occurrence in EBS text book and providing an insight into the use of these lexical cohesive devices thereby hopefully assisting the learning and teaching of BE The findings of the research...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu