estimation of lv filling pressures in patients withnormal efs

Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography

Ngày tải lên : 20/01/2016, 13:07

... Laboratories 127 A Estimation of LV Filling Pressures in Patients With Depressed EFs 127 B Estimation of LV Filling Pressures in Patients With Normal EFs 127 C Grading Diastolic Dysfunction 128 ... when LV ﬁlling pressures are normal, and therefore should not be used as the ﬁnal arbitrator in this setting B Estimation of LV Filling Pressures in Patients With Normal EFs The estimation of LV ... Figure 14 Diagnostic algorithm for the estimation of LV filling pressures in patients with depressed EFs Estimation of Filling Pressures in Patients with Normal EF E/e’ Sep E/e’ > 15 or E/e’...

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Báo cáo y học: "A neonate with left pulmonary artery thrombosis and left lung hypoplasia: a case report" pps

Ngày tải lên : 11/08/2014, 03:21

... angiography showing a filling defect in the lumen of the left pulmonary artery (LPA) consistent with LPA thrombosis of a thrombus (Figure 3) In addition, large collateral vessels originated from ... screening evaluation for a possible inherited thrombophilia disorder was completed in this baby Blood levels for protein C, protein S, antithrombin activity, concentrations of clottable fibrinogen, ... vessels originating from the aorta and supplying the left lung were previously described with LPA thrombosis at birth and clinical evidence of PPHN [4,12] No reported cases were found of infants...

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Báo cáo y học: " A neonate with left pulmonary artery thrombosis and left lung hypoplasia: a case report" pot

Ngày tải lên : 11/08/2014, 07:20

... angiography showing a filling defect in the lumen of the left pulmonary artery (LPA) consistent with LPA thrombosis of a thrombus (Figure 3) In addition, large collateral vessels originated from ... screening evaluation for a possible inherited thrombophilia disorder was completed in this baby Blood levels for protein C, protein S, antithrombin activity, concentrations of clottable fibrinogen, ... vessels originating from the aorta and supplying the left lung were previously described with LPA thrombosis at birth and clinical evidence of PPHN [4,12] No reported cases were found of infants...

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Báo cáo y học: "Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamsters" doc

Ngày tải lên : 12/08/2014, 11:21

... the decrease of Ang I One unit (U) of activity was defined as the amount of enzyme producing ng Ang I decrease per The activity not inhibited in the presence of lisinopril, aprotinin and EDTA ... Up-regulation of chymase expression in smoke-exposed lungs To determine whether chymase is involved in cigarette smoking-induced pulmonary artery remodeling and PAH, chymase protein and mRNA levels in the ... chymostatin administration significantly reduced the smokeinduced increase in chymase activity but had no effect on ACE activity, suggesting that chymostatin was mainly acting through the inhibition of...

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Báo cáo y học: "Acute pressure overload of the right ventricle. Comparison of two models of right-left shunt. Pulmonary artery to left atrium and right atrium to left atrium: experimental study" doc

Ngày tải lên : 10/08/2014, 09:22

... shunts in a porcine model Page of 10 external jugular vein which was surgically dissected; a right side arterial line was inserted under direct vision by a small incision in the groin, and in the ... followed by continuous IV infusions of thiopental sodium (1 mg/min), fentanyl citrate (4 mg/min), pancuronium bromide (0.25 mg/min), and lidocaine (2 mg/min), throughout the experiment After intubation ... groups concerning the percentage change from baseline to 10 minute of the pCO2 of the left atrium variable (p = 0.016) and the percentage change from baseline to 20 minute of the pCO2 of the left...

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báo cáo khoa học: "Anomalous origin of the left coronary artery from the pulmonary artery associated with an accessory atrioventricular pathway and managed successfully with surgical and interventional electrophysiological treatment: a case report" docx

Ngày tải lên : 10/08/2014, 23:20

... normalization of heart rate In our patient, the initial cause was not immediately obvious The occurrence of SVT in infancy is well known, but to the best of our knowledge the combination of ALCAPA ... the treatment of choice in older children with recurrent SVT [3-6], the application of this treatment in infancy is undertaken only after failure of pharmacological therapy and in patients with ... life-threatening arrhythmias The main reasons for this approach are the natural history of SVT with resolution of episodes in infancy [3-6], the risk of damage to the coronary arteries and intra-cardiac...

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Báo cáo y học: " Response of pulmonary artery intimal sarcoma to surgery, radiotherapy and chemotherapy: a case report" docx

Ngày tải lên : 11/08/2014, 21:22

... and seeding of emboli [1,2] Intimal sarcoma is a rare tumor, and the incidence of PA intimal sarcoma is almost twice that of sarcomas of aortic origin It mainly occurs in adults within the age ... discharged Figure spindle cells Pathological findings of surgical specimen show abundant Pathological findings of surgical specimen show abundant spindle cells Hematoxylin and eosin stain ×100 Thirteen ... gender variation in the incidence of aortic intimal sarcoma The mean age of patients diagnosed with PA intimal sarcoma is 48 years, while the mean age of patients at diagnosis of aortic intimal sarcoma...

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Báo cáo y học: " Endothelial cell apoptosis in chronically obstructed and reperfused pulmonary artery" pps

Ngày tải lên : 12/08/2014, 15:21

... leading to endothelial damage Our results indicating overexpression of pro-apoptotic proteins, including Thsp-1 and PAI-1, prompted us to investigate the effects of a nonselective inhibitor of ... microscope after Hoechst staining (Sigma, Saint-Quentin Fallavier, France) Then, ECs in the proximal and distal PA were counted in a blinded fashion by two investigators working independently from each ... values (Figure 5B) Effect of pentoxifylline Injecting pentoxifylline immediately before reperfusion resulted in a significant decrease in the proportion of apoptotic ECs in the distal PA, from 46.4...

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Báo cáo y học: " Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cells" docx

Ngày tải lên : 12/08/2014, 16:20

... interaction is perhaps not surprising given the critical role of the cAMP-protein kinase A signalling pathway in regulating the expression, activity and intracellular localization of PDE4 isoforms ... release of gelatinase activity from PASMCs and this may be significant in the light of recent findings indicating that prednisolone selectively inhibits the proliferation of PASMCs from patients ... min, gels were stained in 0.25% Coomassie blue for 1–2 h and destained in fixing/destain solution until bands of activity were clearly visible The presence of MMP activity was confirmed by inhibition...

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Báo cáo y học: " Pro/con clinical debate: Pulmonary artery catheters increase the morbidity and mortality of intensive care unit patients" potx

Ngày tải lên : 12/08/2014, 19:22

... data is often incorrectly interpreted and utilized The current standard of practice is to insert a PAC in cases of hemodynamic uncertainty As there is no data supporting a beneficial effect of the ... potentially harmful intervention when assessing clinical data in a case study provided Subsequent to insertion of a PAC, the range of treatments and the number of harmful interventions were reduced ... afterload, altering filling pressures independent of volume changes [7] Will this information change my management? Can the PAC provide this information reliably? Various factors influence the...

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Báo cáo khoa học: "The concentration of oxygen, lactate and glucose in the central veins, right heart, and pulmonary artery: a study in patients with pulmonary hypertension" ppt

Ngày tải lên : 13/08/2014, 03:20

... position of the catheter at each sampling site and the blood sampling procedure was performed within a span of min, with no changes noted in heart rate or blood pressure in any of the patients Finally, ... idea of mixing SVC and IVC blood as the mechanism for development of Δ[Lac] The finding of greater SO2 and [Lac] in IVC and SVC than in pulmonary artery indicates that further dilution of oxygen ... reflecting the high rate of cerebral glucose uptake In adult humans glucose represents the main, if not the sole, substrate of brain energy metabolism, with the brain utilizing approximately 25% of...

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Báo cáo y học: " Pulse-pressure variation and hemodynamic response in patients with elevated pulmonary artery pressure: a clinical study" ppt

Ngày tải lên : 13/08/2014, 20:22

... decreased in none of the fluid challenges resulting in increased SV, and in 44% of those in which SV did not increase (P = 0.0003) EDV increased in 28% of fluid challenges resulting in increased ... tested this in a clinical context in which fluid infusion is unavoidable (that is, in patients with septic shock and in patients immediately after cardiac surgery) Instead of selecting patients ... SV and in 45% of those in which SV did not increase (P, not significant) Discussion The main finding of this study was the lack of association between PPV and volume responsiveness in patients...

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Báo cáo y học: "Pulse pressure variation and volume responsiveness during acutely increased pulmonary artery pressure: an experimental study" doc

Ngày tải lên : 13/08/2014, 20:22

... line, all fluid challenges; dashed line, fluid challenges with concomitant increase in central venous pressure; thin solid line, line of identity during an endotoxemia-induced acute increase in ... loaded as in our experiments The descent of the diaphragm can therefore result in transfer of abdominal volume to the chest, and thus in an increase of right ventricular filling during inspiration ... preceding hemorrhage Solid line, all fluid challenges; dashed line, fluid challenges with concomitant increase in central venous pressure; thin solid line, line of identity Discussion The main finding...

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Báo cáo y học: "Cross-comparison of cardiac output trending accuracy of LiDCO, PiCCO, FloTrac and pulmonary artery catheters" docx

Ngày tải lên : 14/08/2014, 07:21

... > 250 cc of PRBC, FFP, platelets or 0.9% saline given over < 30 min) Inotrope (any Δ > 0.01 μg/kg/min in epinephrine or > μg/kg/min in dopamine or dobutamine infusion) 10 Combination of any two ... L/min 2.11 L/min 0.27 L/min -1.57 L/min 1.46 L/min -0.10 L/min -1.65 L/min 1.30 L/min 0.30 L/min -0.70 L/min 1.59 L/min -0.27 L/min -2.13 L/min Figure Bland-Altman analysis of each set of paired ... COtd 1.54 L/min -0.10 L/min -2 -1.75 L/min -4 10 12 CCO 1.80 L/min 0.49 L/min -0.81 L/min -2 -4 -6 -0.72 L/min -2 -4 10 12 -4.81 L/min 10 CCO LiDCO 1.10 L/min -0.31 L/min -1.72 L/min -2 -4 10...

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Aging of the Respiratory System: Impact on Pulmonary Function Tests and Adaptation to Exertion pdf

Ngày tải lên : 05/03/2014, 21:20

... decrease in Pao2 with age was minimal (6 mm Hg) Most of the variance of V/Q mismatch was not a result of aging and remained unexplained; the role of an increase in closing volume with aging was ... consistently find an increase in the average distance between airspace walls (mean linear intercept) and a decrease in the surface area of airspace wall per unit of lung volume beginning in the third ... decrease in Pao2, increase in alveolar-arterial difference in partial pressure of oxygen (Pao2 À Pao2), and decrease in carbon monoxide transfer, measurement of V/Q inequality using the multiple inert...

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Sputum smear negative pulmonary tuberculosis: sensitivity and specificity of diagnostic algorithm docx

Ngày tải lên : 15/03/2014, 03:20

... and physical examination was done by a study clinician and the findings were recorded on a clinical record form The investigators did not interfere in the treatment of these patients The treatment ... culture positive for MTB in 27.2% (127/ 467) of patients; samples of 11.1% (52/467) patients were reported to have been contaminated In the remaining 61.7% (288/467) patients sputum was culture ... facilities of doing cultures are prohibitive in most developing countries Sputum smear microscopy remains the main diagnostic tool for PTB that allows initiation of treatment and monitoring of patient...

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Báo cáo khoa học: Heme oxygenase-1 ⁄p21WAF1 mediates peroxisome proliferator-activated receptor-c signaling inhibition of proliferation of rat pulmonary artery smooth muscle cells pot

Ngày tải lên : 15/03/2014, 10:20

... families of proteins: inhibitor of kinase ⁄ alternative reading frame and CDK inhibitor protein ⁄ kinase inhibitor protein The inhibitor of kinase ⁄ alternative reading frame family includes p16INK4a ... cell cycle in the G1 phase by binding to, and inactivating, cyclin–CDK complexes [29,30] The results of our PPARc inhibition of cell proliferation study reveal that activation of PPARc increases ... Lipofectamine and incubated at room temperature for 20 Then, the complex of siRNA and Lipofectamine was added to cells, and culture was maintained for 72 h at 37 °C and 5% CO2 in a humidiﬁed incubator...

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Báo cáo Y học: Proteolytic action of duodenase is required to induce DNA synthesis in pulmonary artery ﬁbroblasts A role for phosphoinositide 3-kinase pot

Ngày tải lên : 24/03/2014, 03:21

... toxin, which ADP-ribosylates the a subunit of Gi and Go resulting in blockade of G protein activation, inhibited duodenase-induced [3H]thymidine incorporation by 52 ± 2.5%, suggesting involvement ... [28] Employing a range of selective inhibitors, we investigated the roles of PtdIns 3-kinase, MEK1/ERK, protein kinase C and pertussis toxin-sensitive G-proteins Only partial inhibition of DNA synthesis ... localization of duodenase in bovine intestine and lung Representative positively stained mast cells are indicated by large arrows Panels (a–e) show localization of duodenase in bovine jejenum In panel...

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LABORATORY DIAGNOSIS OF PULMONARY TUBERCULOSIS : CONVENTIONAL AND NEWER APPROACHES+ pdf

Ngày tải lên : 29/03/2014, 03:20

... and this is one of the production of host enzymes (Adenosine Deaminase) important limiting factors in determining the directly in clinical samples TSA is present not sensitivity of PCR assays for ... those of us who are carried away by certain reports coming from research DNA PROBES publications Batches of 200 samples containing Recent developments in the field of molecular varying numbers of ... model of history, examination and sputum microscopy has proved itself capable of detecting the majority of infectious cases and, in conjuction with adequate case-finding and 109 treatment, remains...

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Pulmonary Tuberculosis - Evolution and Clinical picture doc

Ngày tải lên : 29/03/2014, 03:20

... mycobacteria Mode of infection The disease is transmitted through inhalation of infected sputum droplets or ingestion of infected milk Primary Tuberculosis Occurs in the body when it is infected for ... intima , with subsequent discharge of bacilli into the blood stream leading to miliary spread Usually solitary, caseating and liquefying but can later heal by endothelial covering Can occur in ... presentation is with the insidious onset of weight loss, malaise and a fever of unknown origin Anemia is usual and the ESR is often elevated A variety of blood dyscrasias, including leucopenia, pancytopenia,...

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