eosinophilic esophagitis treatment approach in children
WHO guidelines on the pharmacological treatment of persisting pain in children with medical illnesses docx
... with SCD in clinics, day hospitals and inpatient settings (51) 2.4Defining criteria and selecting a pain measurement tool in clinical settings In a clinical setting, the selection of pain scales ... the class of serotonin and norepinephrine reuptake inhibitors for persisting neuropathic pain in children > 10 • Gabapentin for persisting neuropathic pain in children • Ketamine as an adjuvant ... guidelines on the pharmacological treatment of persisting pain in children with medical illnesses WHO Library Cataloguing -in- Publication Data Persisting pain in children package: WHO guidelines...
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báo cáo hóa học:" Traumatic extremity arterial injury in children: Epidemiology, diagnostics, treatment and prognostic value of Mangled Extremity Severity Score" pdf
... 10years study period in children aged 13 years or younger [10] But again, iatrogenic as well as traumatic arterial injuries were included in this study [10] Bearing in mind that iatrogenic lesions ... ethical standards laid down in the 1964 Declaration of Helsinki Informed consent was obtained from all patients (or their relatives) included in the investigation Inclusion and exclusion criteria ... http://www.josr-online.com/content/5/1/25 cal treatment protocols were performed individually in every patient depending on age, severity of vascular lesions and accompanying injuries In general, there...
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báo cáo hóa học: " Impaired sleep affects quality of life in children during maintenance treatment for acute lymphoblastic leukemia: an exploratory study" pdf
... used in pediatric oncology studies [22,32-34] and includes subscales with age-specific questions for determining problems in relevant areas during cancer treatment such as pain, nausea, treatment ... sleepiness and night wakenings Similar results have been found in children with chronic pain [13] and children referred to a sleep disorder clinic [20], but was not yet demonstrated in children ... Hinds et al.[4] performed actigraphy in children with ALL and found that dexamethasone alters sleep During dexamethasone treatment duration of sleep was increased and there was an increase in...
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báo cáo hóa học:" Psychometric properties of the DISABKIDS Chronic Generic Module (DCGM-37) when used in children undergoing treatment for cancer" pdf
... when used in children undergoing treatment for cancer However the dimensionality of the instrument is uncertain which may impact score interpretability Further psychometric evaluation in a large ... children and adolescents were invited to participate in the larger study including three assessments during the first six months of treatment and 101 participated in all the assessments The second ... acceptable psychometric properties in children undergoing treatment for cancer Data quality was satisfying with overall acceptable amount of missing values Missing responses were primarily associated...
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Báo cáo toán học: " Influence of different flow conditions on the occurrence and behavior of potentially hazardous organic xenobiotics in the influent and effluent of a municipal sewage treatment plant in Germany: an effect-directed approach" pot
... effluent within the whole treatment process Similar findings for CBZ are mentioned in the literature [6] At this point, there is no information about the relevant metabolites of CBZ in raw and ... endorsed in the present study Page of 13 (Figure 4) In summary, the polar fraction exhibited, in comparison with the other remaining wastewater fractions, the highest inhibition values in the influent ... temperature of 280°C Injection volume was μL The oven temperature was programmed from 90°C (held for min) to 220°C at 15°C min-1 (held for min) and finally to 280°C at 6°C min-1, keeping the final temperature...
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Báo cáo y học: "Eotaxin and FGF enhance signaling through an Extracellular signal-related kinase (ERK)-dependent pathway in the pathogenesis of Eosinophilic Esophagitis" doc
... interferon-inducible protein 10 (IP10); leptin; monocyte chemotactic protein-3 (MCP3); monokine induced by gamma interferon (MIG); macrophage inflammatory protein alpha (MIP-1a); macrophage inflammatory ... blood immune indicators in the disease; we will continue to study other eosinophilic gastroenterological disorders such as eosinophilic gastroenteritis and eosinophilic colitis to determine the role ... eotaxin signaling and increase eosinophil lifespan, respectively Conclusions Subjects with eosinophilic esophagitis had different immune indicator profiles, specifically with increases in basic...
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Báo cáo y học: " Mannose-binding lectin deficiency with eosinophilic meningoencephalitis due to Angiostrongylus cantonensis in children: a case series" pot
... a MBL, mannose-binding lectin; IgA, immunoglobulin A; IgG, immunoglobulin G, IgM, immunoglobulin M; IgE, immunoglobulin E; C3c, complement C3c; C4, complement C4; n.d., no data in blood of the ... demonstrated associations between low-producing MBL-encoding alleles and an increased risk of infection in both children and adults These associations are strongest in infants at an age when passively acquired ... helped with protein analysis and in drafting the manuscript All authors read and approved the final manuscript Competing interests The authors declare that they have no competing interests Received:...
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TREATMENT OF BIPOLAR DISORDER IN CHILDREN AND ADOLESCENTS - PART 1 ppsx
... recognition as a clinical investigator Dr Findling is the principal investigator of a National Institute of Child Health and Human Development contract examining lithium in the treatment of pediatric ... may have limited utility for individual patients in the clinical setting Biological markers for treatment response may be more useful in individualizing treatment planning 24 Neuropharmacology 25 ... medicines, including Saint-John’s-wort and S-adenosyl-L-methionine (SAMe) The next two chapters examine the importance of including psychosocial interventions in the treatment plan for children and adolescents...
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TREATMENT OF BIPOLAR DISORDER IN CHILDREN AND ADOLESCENTS - PART 2 pps
... Lithium inhibits inositol monophosphatase, resulting in increased inositol monophosphate, as well as an increase in the PME peak It has been reported that lithium-associated increases in PME concentrations ... adult studies help to inform the treatment of early-onset bipolar disorder in the absence of comparable data in children As interest in treatment of bipolar disorder in children and adolescents ... (Goodnick & Schorr-Cain, 1991) and angiotensin con- 48 DIAGNOSIS AND TREATMENTS verting enzyme (ACE) inhibitors may cause an increase in lithium levels Perhaps more pertinent to children and teenagers,...
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TREATMENT OF BIPOLAR DISORDER IN CHILDREN AND ADOLESCENTS - PART 4 pdf
... carbamazepine Lithium Multiple Verapamil Carbamazepine add on Lithium Lecithin Tamoxifen Nimodipine Diltiazem Diltiazem Nifedipine Nimodipine Nimodipine Nimodipine Nimodipine Nimodipine Nimodipine ... tion of treatment) , including Stevens–Johnson syndrome, is approximately in 100 (1%) in children age less than 16 years and in 1,000 (0.3%) in adults (Glaxo, 2001) Drug Interactions Lamotrigine is ... discontinuation of nimodipine Yingling and colleagues report the use of nimodipine in the treatment of a pregnant patient with bipolar disorder (Yingling, Utter, Vengail, & Mason, 2002) She was being...
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TREATMENT OF BIPOLAR DISORDER IN CHILDREN AND ADOLESCENTS - PART 5 ppsx
... triggers, tool kit, taking charge of mad, sad, bad feelings Negative family cycles; thinking, feeling, doing Thinking, feeling, doing Problem solving for parents Problem-solving skills School services ... cotherapist lead the child group The final 15–20 minutes of the children s session is spent in in vivo social skills training, in which children engage in recreational activities and noncompetitive ... participate in treatment An individualized treatment allows the patient’s treatment needs to be met in a timely manner Finally, some families may be uncomfortable about sharing personal information in...
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TREATMENT OF BIPOLAR DISORDER IN CHILDREN AND ADOLESCENTS - PART 6 pps
... Disentangling the association between bipolar disorder, CD, and SUD is critical in unveiling the role of each disorder independently, or in combination, in mediating SUD For example, in evaluating ... functioning in adults (Block, 1996), although the extent of these findings in youths remains unclear Given the increasingly growing concern with neuropsychological and executive-function defects in predicting ... main mediator of the SUD However, systematic reporting of SUD was not undertaken, and CD in youths was defined, in part, by the presence of SUD, confounding the role of juvenile CD in predicting...
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TREATMENT OF BIPOLAR DISORDER IN CHILDREN AND ADOLESCENTS - PART 7 docx
... including cognitive-behavioral therapy, social problem-solving skills training, and parent management training involving child and/or parent for 12– 25 sessions (Farley et al., 2005) Though treatment ... package insert labeling information approved by the U.S Food and Drug Administration (FDA) Along these lines, in those circumstances in which the clinical indication appears highly compelling, specific ... the treatment of CD in youths primarily utilizes psychosocial interventions A recent report (Tcheremissine & Lieving, 2006) addressing the pharmacological aspects of the treatment of CD in children...
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TREATMENT OF BIPOLAR DISORDER IN CHILDREN AND ADOLESCENTS - PART 8 docx
... controlled Fluoxetine Sertraline TCA Sertraline Fluoxetine Paroxetine/ imipravine Fluvoxamine Fluvoxamine Citalopram Fluoxetine Adverse events not described Agitation Mania Hyperkinesia Hyperkinesia Emotional ... fluoxetine inhibit cytochrome P450 3A4 that may lead to an increase in carbamazepine levels When fluvoxamine and clozapine are Treatment of Bipolar Depression 315 coadministered, the dose of clozapine ... two groups in improvement in depressive symptoms The final Children s Global Assessment Scale (CGAS) scores in both groups, though improved, were still below 60, indicating continuing clinical problems...
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TREATMENT OF BIPOLAR DISORDER IN CHILDREN AND ADOLESCENTS - PART 9 doc
... peripheral insulin sensitivity and, consequently, hyperinsulinemia were pivotal to the pathogenesis of PCOS Hopkinson hypothesized that insulin acts in the liver to inhibit the production of insulin-like ... growth factor (IGF-1) binding protein and SHBG, with the latter leading to an increase in free testosterone Therefore, according to Hopkinson, insulin resistance not only increases the secretion ... adopted widely in psychiatric practice involving youngsters Whereas in adults the BMI is calculated either as weight in kg/height in meters2 or weight in pounds × 703/height in inches2, in children...
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TREATMENT OF BIPOLAR DISORDER IN CHILDREN AND ADOLESCENTS - PART 10 pps
... without fasting In addition, the stable glucose finding is also not entirely surprising, as in youngsters with intact pancreatic beta cell reserve, one would not expect to find an initial rise in glucose ... youths include controlling the environment, monitoring behavior, setting goals, rewarding successful behaviors, identifying and solving problems, and adapting parental skills (Dietz & Robinson, ... olanzapine, and quetiapine, are also used off-label to control symptoms of mania in children Risperidone was approved for the treatment of mania in children age 10 and older in 2007 It must be pointed...
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báo cáo khoa học: " New genetic links in eosinophilic esophagitis" pdf
... activity, including Th2 cytokine and chemokine production These findings [13] suggest a unique potential mecha nism for the induction of EoE Could food allergens trigger the TLR-3 receptor, inducing ... MR, Collins MH, Cohen MB, Akers R, Hogan SP, Assa’ad AH, Putnam PE, Aronow BJ, Rothenberg ME: Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis J Clin Invest ... pathways for treatment The current treatment options for EoE involve the avoidance of the trigger (foods) and the treatment of the underlying inflammation with topical corticosteroids [1] Treatment...
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Báo cáo y học: " Comparative efficacy and acceptability of methylphenidate and atomoxetine in treatment of attention deficit hyperactivity disorder in children and adolescents: a meta-analysis" pdf
... have been used in the treatment of ADHD The non-stimulant atomoxetine was introduced in the United States in 2002 It is a selective norepinephrine reuptake inhibitor Double blind studies have ... difference in treatment effect between the two medications Meta-analysis allows pooling of data from all head to head trials and the findings will help clinicians in selecting medications for treatment ... comparing atomoxetine and methylphenidate in treatment of ADHD in children and adolescents Placebo controlled trials have established that both methylphenidate and atomoxetine are effective in treatment...
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Báo cáo khoa học: "Rescue treatment with terlipressin in children with refractory septic shock: a clinical study" ppt
... Noradrenaline 153.5 (67–460) aInotropic equivalent: (noradrenaline × 100) + (adrenaline × 100) + dopamine + dobutamine + (milrinone × 15) [25] * P < 0.05 versus baseline ** P < 0.01 versus baseline in ... vasopressin levels in children with meningococcal septic shock Intensive Care Med 2003, 29:1339-1344 Vasudevan A, Lodha R, Kabra SK: Vasopressin infusion in children with catecholamine-resistant ... reversing hypotension in children with catecholamine-resistant septic shock • TP therapy permitted lowering of the high doses of noradrenaline needed in these patients • TP therapy in combination...
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Báo cáo khoa học: " Surfactant for acute respiratory failure in children: where should it fit in our treatment algorithm" doc
... within the first days in another [8] The timing of surfactant use was not stated in the remaining two trials [11] Patients with milder degrees of hypoxia (oxygenation index 5–7) were enrolled in ... and cons of using surfactant in each individual patient to decide whether the surfactant benefits outweigh the financial implications and risks in that particular patient Competing interests The ... reported in this meta-analysis only involved infants with viral bronchiolitis, who responded well to surfactant [1] Only three of the trials involved older children with acute lung injury from...
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