... degradation of PS cofactors using synoviolin-null cells, as PS cofactors undergo the ubiquitin ⁄ proteasome pathway We report that Synoviolin is involved in the degradation ofimmature NCT and regulates ... Results Accumulation ofimmature NCT in synoviolin-null cells To investigate whether Synoviolin is involved in the degradation of PS cofactors, we first compared the levels of PS cofactors by immunoblotting ... degradation of nicastrin T Maeda et al NCT is one of the essential cofactors of the c-secretase complex We therefore investigated the effect of the Synoviolin-mediated degradation of NCT on Ab...
... pattern of viral attachment (PVA) ofhumanand AIVs in pig tissues, we focused on the expression in epithelial cells and glands of NE, TE and BE and in bronchioles and alveoli of LE An overview of ... identified in humans [34,35,40], ducks and quail [16,41], and Thompson and colleagues [39] have generated data indicating that co-infection ofhuman ciliated epithelial cells with humanand avian ... with a pandemic potential On the other hand, the generation of pandemic influenza viruses in pigs appears to be a rare and complex process, and the 2009 H1N1 influenza virus is the first pandemic...
... conditions and in the absence of crystal contacts In this study, we have carried out single-particle image reconstruction of the ECD dimer with and without bound ANP using electronmicroscopy ... mechanism Fig Single-particle EM of apoECD and ANP–ECD (A) Representative electron micrograph and (B) class averages obtained for apoECD Similar electron micrographs and class averages were obtained ... the solution structures of apoECD and ANP–ECD The fluorescence emission spectra of apoECD and ANP–ECD are shown in Fig 4C Comparison of the spectra shows that addition of ANP causes an approximately...
... facilitated the determination of both thermodynamic and kinetic properties of NR1, and as we have shown for CPR and P450 BM3 (23,24,28) the properties of the flavin binding domains of NR1 are likely to ... reduction of substrate (DCPIP or ferricyanide) at appropriate wavelengths (600 nm and 420 nm, respectively) Results are the mean and standard deviation of triplicate assays For the determination of ... detailed analysis ofelectron transfer between dithionite reduced FAD/NADPH domain and the oxidized FMN domain The lack of a second order dependence of the observed rate for interdomain electron transfer...
... alive”) of sample to escape from the damage of reagents, strong electrical field, and ultrahigh vacuum in electron microscopy, and so on [22,23] Therefore, a comparative study ofimmatureandimmature ... size of × μm and the mature BMDCs (L) in the scanning size of × μm; F and M, Enlarged view of the center of the immature BMDCs (F) and the mature BMDCs (M) in the same scanning area of × μm; G and ... comparison of both immatureand mature BMDCs Thus, the foregoing results would be helpful for profoundly understanding the morphologic properties and functional foundation of both immatureand mature...
... while a fraction of the electrons are inelastically scattered and lose a part of their energy due to electron- electron interaction EELS is the analysis of the energy distribution of electrons that ... Temperature andelectron beam induced phase transformation to understand the structural stability of nanomaterials Growth and phase transitions of nanomaterials In situ measurement of properties of individual ... structures and measurements of electronic and chemical properties of nanomaterials, advanced manufacturing is another foundation of nanotechnology We need to improve the performance and capabilities of...
... image of this white film Large quantities of nanowires, with diameters of 80-100 nm and lengths of 10-100 µm could be produced by simple thermal evaporation of 96 Chapter Mechanistic Study of Zinc ... broadening The relaxation of the wave-vector selection rule in these nanocrystals and the size distribution of the wires led to a shift and broadening of the FWHM of the TO and LO peaks Apart from ... before (lower) and after (upper) exposure to NH3, showing the B 1s and N 1s K-edges, and a notable absence of carbon TEM observation of the particles revealed excellent size uniformity, and figure...
... from the L23 edge of Si, and the K edge of C and O Silicon is found in both the body and the tip of the cone although the Si signal at the tip arises from the overlap of the Ni M and Si L edge Carbon ... family of planes The {111} family of planes consist of four planes: (111), ( 11 ), (1 1 ) and (11 ) and their opposites The switch of directions between these planes results in the bending of the ... patterns and intensities EI-MS of In(SePh)3 also contains a weak ion peak of In(SePh)3·+, strong peaks of Ph2Se2·+ and SePh2·+, similar to In(SPh)3·+, Ph2S2·+ and SPh2·+ From the existence of the...
... Comparison of physical properties of TiSi2, CoSi2 and NiSi 21 Table A.1: Ratio of square of d-spacing between Si (200) and Si (220) planes 120 Table A.2: Showing the comparison and analysis of the ... transmission electronmicroscopyElectronmicroscopy can be seen to be superior in a number of ways to conventional visible light microscopy1 This is primarily due to the shorter wavelength of electrons ... to (b) outlines the stages of the expansion of the NiSi portions of island ‘I’ This is followed by the propagation of the NiSi:NiSi2 interface at one end of the island, until the whole NiSi portion...
... STRUCTURE AND SOME MAJOR LINGUISTIC FEATURES OF THE INTERNATIONAL DECLARATION ON HUMAN RIGHTS 3.1 Definition of an International Declaration 10 3.2 Purposes and typical legal characteristics of the ... of the Declaration and its realization 13 3.3.2.2 Remarks 14 a, Use of Grammar 14 a1 Modality 14 a2 Use of Active / Passive voices 14 a3 Sentence order 15 a4 Length of sentences 15 a5 Kinds of ... 4.3 A study of discourse structure and some major linguistic features of the International Convention on Human Rights in comparison with those of the International Declaration on Human Rights...
... Justification, Relation of Cause, Purpose, Condition and Otherwise, Interpretation and Evaluation, Restatement and Summary, and lastly Sequence and Contrast The types of relation between N and S not completely ... declaration ofhuman rights as a common standard of achievement for all peoples and all nations(last phrase of the Preamble) + The purposes, basis (theoretical, practical and legal basis) and reasons ... Beginning: Title and Preamble 4.3.1.1 The Title and Preamble of the Convention and their realization * Similizing with the Title and Preamble of a Declaration, the Title and Preamble of a Convention...
... the Charter of the United Nations, recognition of the inherent dignity andof the equal and inalienable rights of all members of the human family is the foundation of freedom, justice and peace ... right to a standard of living adequate for the health and well-being of himself andof his family, including food, clothing, housing and medical care and necessary social services, and the right ... Declaration of the Rights of the Child of 1924 and in the Declaration of the Rights of the Child adopted by the General Assembly on 20 November 1959 and recognized in the VIII Universal Declaration of Human...
... parts of the human body The position of proverbs referring to part of the human body Parts of the human body 21 21 21 The classification of parts of the human body according to position Graduation ... content of an idiom is that of concept and the content of a proverb is that of judgement So the relationship between proverb and idioms is the relationship between concept and judgement The form of ... of technology and information and the exchanges are greatly increasing lead to the demand for learning and teaching of foreign languages and interpretation Contrastive Analysis (C.A) is one of...
... the type of transference which has taken place The eye of a man - The eye of a potato The bowel of a person - The bowel of the earth The hand of a child - The hand of a lock The heart of a man ... analysis of class of words denoting parts ofhuman body in English and VietNamese on semantic transference 2.1 The origin of names referring to parts of the human body According to the aspect of origin, ... percentage of the forms of each types of semantic transference and the percentage of the types of semantic transference used in these classes Table 2: The percentage of the forms of each type of semantic...
... characterization of numerous complexes of the human HPRT and several bacterial and protozoan HPRTs have been undertaken [13–17] The structure ofhuman HPRT can be divided into two domains: a core domain and ... Studies of the human PRTFDC1 M Welin et al 300 mm NaCl, and mm MgCl2 Following initial screening, a subset consisting of IMP, GMP, XMP, AMP, CMP and PRPP were screened at 500 lm and 10 mm, with mm and ... the base of bound GMP is stacked between Val143 and Phe194 N1, N2 and O6 of the nucleotide form hydrogen bonds to main chain atoms, whereas the side chain of Lys173 interacts with both O6 and N7...
... of ionic strength and Mg2+ on the activity and specificity of OGG1, we measured the apparent values of k2 and k3 under conditions of low salt (KPi only) and no Mg2+, low salt and 20 mm Mg2+, and ... Activity and specificity of Fpg and OGG1 in buffers with different concentrations of KCl and MgCl2 (A–C) Fpg, (D–F) glycosylase activity of OGG1, (G–I) AP lyase activity of OGG1 The extent of cleavage ... Activity and specificity of Fpg and OGG1 in buffers with different concentrations of KGlu and MgCl2 in the presence of KPi (A–C) Fpg, (D–F) glycosylase activity of OGG1, (G–I) AP lyase activity of OGG1...
... rates of uptake of both the lipid and protein components are not matched by the rate of cellular metabolism of these species, resulting in the accumulation of both unmodified cholesteryl esters and ... consists of two related processes ) oxidation of protein-bound sugars (from glycation), and oxidation of free glucose and its products Both processes can generate radicals that modify LDL, and hence ... turnover of the apoB protein It is shown that both lipid and protein are taken up, in a time-dependent manner, via scavenger receptor SR-A- and CD36-mediated processes, and that the uptake of lipid and...
... Roles of the HsRad51 L1 and L2 loops D231W (L1 loop) Table Changes in the fluorescence of tryptophan probes inserted in the L1 and L2 loop upon binding of nucleotides and DNA The fluorescence of modified ... Alignment of the HsRad51 sequence to those of MvRadA, Pyrococcus furiosus Rad51 (PfRad51), and ScRad51 around the L1 and L2 loops The L1 and L2 loops, which are invisible in the crystal structure of ... 22, 26, and 30), lM (lanes 3, 7, 11, 15, 19, 23, 27, and 31), and lM (lanes 4, 8, 12, 16, 20, 24, 28, and 32) salt-induced ATPase activity very similar to that of HsRad51 in the absence of DNA...