dynamic docking study of the binding of 1 chloro 2 4 dinitrobenzene in the putative electrophile binding site of naturally occurring human glutathione

A validated molecular docking study of lipid–protein interactions

Ngày tải lên : 28/11/2015, 14:01

... 2 01 Figure 6 .1 Binding of Anandamide to CB1 20 8 Figure 6 .2 Binding of anandamide to CB2 21 0 Figure 6.3 Binding of 2AG to CB1 21 1 Figure 6 .4 Interactions of ... Specific binding of COX -2 with C14DHA 23 8 Figure 7.8 Binding of C14EPA to PPAR-γ in presence of unlabeled DHA 2 41 17 Figure 7.9 Competitive binding of PPAR-γ 24 2 Figure 7 .10 ... C14DHA 23 3 Table 7.3 Total binding of COX -2 with C14DHA 23 7 Table 7 .4 Specific binding of COX -2 with C14DHA 23 7 Table 7.5 Binding of C14EPA to PPAR-γ in presence of...

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Tài liệu Báo cáo Y học: Studies on the nonmevalonate pathway of terpene biosynthesis The role of 2C-methyl-D -erythritol 2,4-cyclodiphosphate in plants docx

Ngày tải lên : 22/02/2014, 07:20

... 26 . 74 39. 72 13 5.33 12 4. 41 26 .68 40 .49 13 9. 51 120 .22 12 3.35 25 .69 17 .68 16 .00 16 . 04 16 . 52 42 . 3 17 , 17 0 42 . 5, 3.5 42 . 5 18 , 18 0 42 . 5, 3.5 42 . 2 19 , 19 0 40 .7 42 . 0 20 , 20 0 13 43 .3 42 . 2 42 . 2 42 . 2 42 . 0 a ... 1, 10 2, 20 3, 30 4, 40 5, 50 d 6, 60 7, 70 8, 80 9, 90 d 10 , 10 0 11 , 11 0 12 , 12 0 13 , 13 0 14 , 14 0 15 , 15 0 16 , 16 0 17 , 17 0 18 , 18 0 19 , 19 0 20 , 20 0 13 1 .23 12 3.97 26 .77 39. 72 13 4. 93 12 4 .22 26 . 74 ... d 10 , 10 0 11 , 11 0 12 , 12 0 13 , 13 0 14 , 14 0 15 , 15 0 16 , 16 0 17 , 17 0 18 , 18 0 19 , 19 0 20 , 20 0 ND 1. 1 1. 1 ND ND 1. 3 1. 3 ND ND 1. 1 1. 2 1. 5 10 .5 1. 1 1. 0 1. 8 9.0 9.8 8.5 8.9 86 c c c C a (%) C– 13 C b...

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Báo cáo sinh học: " Evolution of naturally occurring 5''''non-coding region variants of Hepatitis C virus in human populations of the South American region" doc

Ngày tải lên : 18/06/2014, 18:20

... [AM7096 72] [AM709678] [AM709670] [AM70 947 4] 4 511 03850 4 5 12 098 81 4 5 12 025 63 4 5 12 00 819 4 5 12 025 94 4 5 12 016 41 4 5 12 017 14 4 5 12 049 50 4 5 12 011 57 4 5 12 0 12 08 4 5 12 05577 4 5 12 09889 4 5 12 030 54 13 183 12 713 12 577 13 41 0 12 573 ... AY 446 0 64 AY 446 037 31 AF 011 753 AY 446 044 AY 446 045 AY 446 038 AY 446 057 AY 446 058 AF 011 7 51 42 AY 446 040 AY 446 047 AY 446 060 DQ 010 313 DQ0 613 22 M 848 65 DQ0 613 26 DQ0 613 01 88 DQ0 613 03 61 AY 446 0 51 AY 446 0 52 AY 446 053 ... DQ0 613 23 AY 446 050 AY69 543 7 DQ0 613 12 DQ0 613 10 AY 446 059 AY 446 0 61 DQ0 613 25 AY 446 039 AY 446 065 AY 446 0 62 27 AY 446 043 AY 446 036 AF009606 AY 446 0 41 AF 011 7 52 AY 446 048 DQ0 613 17 AY 446 0 42 DQ0 613 18 AY 446 049 AY 446 064...

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Báo cáo sinh học: "Comparative study of clinical grade human tolerogenic dendritic " pptx

Ngày tải lên : 18/06/2014, 19:20

... 8 . 24 10 10 5 0.3 9 .4 010 2 2. 04 10 3 10 4 10 5 10 2 SSC-A 10 5 1. 4 10 .7 010 2 5. 21 103 10 4 10 5 10 2 48 .1 Cells 32 10 5 0.38 4 . 12 010 2 2 .4 10 3 10 4 10 5 10 2 55 .2 Cells 22 .3 0 10 00 20 00 ... 10 2 4. 06 010 2 66.7 4 .23 10 5 31. 4 010 2 10 3 10 4 10 5 10 4. 85 3.5 69 .4 010 2 10 5 28 10 3 10 4 10 5 10 3 10 10 2 73.7 10 60 .1 25 .8 10 3 10 4 10 5 10 10 5 1. 36 10 6 .16 010 2 10 00 20 00 ... 3000 40 00 FSC-A 10 10 2 74 .2 20 .1 103 10 4 10 5 10 5 39.9 10 10 00 20 00 3000 40 00 FSC-A 10 54. 9 10 10 10 10 2 75.9 10 5 1. 93 10 10 2 26.6 10 3 10 4 10 5 10 10 10 5 2. 69 10 010 2 10 10 00...

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báo cáo hóa học:" Comparative study of clinical grade human tolerogenic dendritic cells" potx

Ngày tải lên : 20/06/2014, 03:20

... 8 . 24 10 10 5 0.3 9 .4 010 2 2. 04 10 3 10 4 10 5 10 2 SSC-A 10 5 1. 4 10 .7 010 2 5. 21 103 10 4 10 5 10 2 48 .1 Cells 32 10 5 0.38 4 . 12 010 2 2 .4 10 3 10 4 10 5 10 2 55 .2 Cells 22 .3 0 10 00 20 00 ... 10 2 4. 06 010 2 66.7 4 .23 10 5 31. 4 010 2 10 3 10 4 10 5 10 4. 85 3.5 69 .4 010 2 10 5 28 10 3 10 4 10 5 10 3 10 10 2 73.7 10 60 .1 25 .8 10 3 10 4 10 5 10 10 5 1. 36 10 6 .16 010 2 10 00 20 00 ... 3000 40 00 FSC-A 10 10 2 74 .2 20 .1 103 10 4 10 5 10 5 39.9 10 10 00 20 00 3000 40 00 FSC-A 10 54. 9 10 10 10 10 2 75.9 10 5 1. 93 10 10 2 26.6 10 3 10 4 10 5 10 10 10 5 2. 69 10 010 2 10 10 00...

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Báo cáo y học: "A cohort study of accidents occurring in mentally handicapped patients living in institutions" pot

Ngày tải lên : 08/08/2014, 23:21

... ( 21 ) (50) 16 (20 ) 12 (17 ) 32 ( 31) 22 (27 ) 10 6 ( 24 .8) Self-harm, n (%) 28 (37) (19 ) 12 (15 ) 13 (18 ) 36 (35) 21 (26 ) 11 3 (26 .4) Disruptive behaviour, n (%) 45 (59) 11 (69) 44 (55) 32 (45 ) 26 (25 ) ... 1. 09 0. 41 to 2. 90 2. 32 1. 28 to 4 .20 Hearing problems (yes) 1. 13 0 . 14 to 9. 34 1. 26 0 .45 to 3 .48 Epilepsy (yes) 1. 15 0. 42 to 3 . 12 1. 69 1. 04 to 2. 76 Taking neuroleptics 9. 32 1. 21 to 71. 83 2. 33 1. 41 ... walk) 55/ 21 14 /2 59/ 21 54 /17 73/30 72 /10 327 /10 1 (76 .4) Autistic, n (%) 37 (49 ) ( 12 .5) 22 (27 .5) 26 (37) 15 ( 14 .5) 32 (39) 13 4 ( 31. 3) Previous accidents, n (%) 19 (25 ) (56) 50 ( 62. 5) 22 ( 31) 58...

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báo cáo khoa học: " Expression of Ets-1, Ang-2 and maspin in ovarian cancer and their role in tumor angiogenesis" pps

Ngày tải lên : 10/08/2014, 10:21

... Ets -1 Maspin Ang -2 P p 11 0.553 0.5 82 0.703 50~ serous Pathological diagnosis p < 50 age 19 12 0.6 51 0 .19 3 0.508 0 .19 7 0 .16 0 0.588 0. 916 0.3 42 0 .49 8 0 .26 8 0. 916 0. 022 0. 8 24 0 .20 9 mucous grade others ... MJ: The paradoxical expression of maspin in ovarian carcinoma Clin Cancer Res 20 02, 8 :29 24 -29 32 doi :10 .11 86 /17 56-9966-30- 31 Cite this article as: Lin et al.: Expression of Ets -1, Ang -2 and maspin ... Sci 20 03, 94: 769-773 10 Yuan HT, Khankin EV, Karumanchi SA, Parikh SM: Angiopoietin is a partial agonist/antagonist of tie2 signaling in the endothelium Mol cell Biol 20 09, 29 :2 011 -20 22 11 Tse...

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Báo cáo y học: " Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system" pdf

Ngày tải lên : 12/08/2014, 13:22

... 0 . 24 7 2. 7 32 11 .08 62 M 0 .29 7 1. 28 3 4. 32 31 M 0.758 0. 620 0. 82 34 F 2. 099 15 . 348 7. 31 41 M 0.330 4. 5 32 13 .73 24 F 1. 040 0 .28 5 0 .27 60 M 0 .4 32 0. 9 14 2 .11 27 31 M M 0.859 1. 778 0 . 24 5 3.387 0 .29 1. 90 ... Treatment) Arm (Test Oil Treatment) 24 33 M M 10 99 25 03 -11 0 - 3 14 25 M 18 25 34 30 F 666 - 12 09 27 M 70 -25 81 22 M 7 01 -43 5 28 M 516 -3 61 10 54 ( 317 ) - 711 ( 346 )† Mean (SEM) *Inflammatory cell counts expressed ... 0 .29 1. 90 10 42 M 0.6 51 1.079 1. 66 11 41 F 1. 1 81 3 . 24 9 2. 75 12 33 M 0. 829 1. 580 1. 91 0.793 1. 4 32 2. 01 Median *Data calculated as fold change after normalization to corresponding b-actin expression...

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A numerical study of airflow through human upper airways

Ngày tải lên : 09/09/2015, 10:15

... morphology 12 1. 2. 2 Airflow in maxillary sinus 15 1. 2. 3 Airflow in human pharynx with motion of surrounding tissues 18 1. 3 Objectives and scope of the study 22 1. 3 .1 Motivations ... 92 4 .2. 2 Results 94 4 .2. 2 .1 Flow partitioning 94 4 .2. 2 .2 Wall shear stress 95 4 .2. 2.3 Flow resistance 97 4 .2. 2 .4 Path-lines ... 11 1 5 .2 .1 Airflow through ostia 11 1 5 .2. 2 Streamlines through sinuses 11 5 5 .2. 3 Nasal airway velocity contours 11 6 5 .2. 4 Sinus velocity contours 11 7 5 .2. 5 ...

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Biodegradable Polymers Composed of Naturally Occurring α-Amino Acids

Ngày tải lên : 25/10/2013, 08:20

... (R=(CH2)2SCH3), L-arginine (R=(CH2)2NHC(=NH)NH2) D is divalent alkyl radical like (CH2)x with x = 2, 3, 4, 6, 8, 12 ; (CH2 )2 O (CH2 )2 , (CH2 )2 O (CH2 )2 O (CH2 )2 , (CH2 )2 O (CH2 )2 O (CH2 )2 O (CH2 )2 O or: O ... , (CH2 )2 O (CH2 )2 O (CH2 )2 , (CH2 )2 O (CH2 )2 O (CH2 )2 O (CH2 )2 Scheme 5.5 Synthesis of DBCs by interacting diols with p-nitrophenyl-chloroformate, method (ii) Cl CO Cl + HOR1 R1 O CO O R1 (AC) ... Macromol Symp., 19 9, 41 9 – 42 9 Katsarava, R and Kharadze, D (19 91) The study of stability of active phenyl esters of carboxylic acids in aprotic polar solvents Zh Obshch Khim., 61 (11 ), 2 41 3 2 41 8 Nathan,...

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Báo cáo khoa học: Computer-assisted mass spectrometric analysis of naturally occurring and artiﬁcially introduced cross-links in proteins and protein complexes potx

Ngày tải lên : 07/03/2014, 12:20

... (p.p.m) 28 28 28 28 28 34 34 34 44 58 44 13 2 13 7 34 34 13 2 13 7 17 0 47 13 2 13 7 47 60 91 170 17 0 11 91. 65d 13 47 .75c 18 05.93c 19 72. 04b 21 7 1.02b 13 01. 82c 13 57.77b 15 23 .88b 11 27 .70a 12 64. 79a 15 23 .56b 23 37 . 14 a ... structure of NK1 (Fig 6) The candidate cross-links in Table suggest crosslinking between the N-terminal part of the protein [Y28 (N-terminus) and K 34] with the region including K1 32, K137 and K170, ... to a peptide with FEBS Journal 27 3 (20 06) 2 81 2 91 ª 20 05 The Authors Journal compilation ª 20 05 FEBS L J de Koning et al 12 4 12 0 11 0 10 0 90 80 70 60 50 40 30 20 10 V S A D F H V P V Y P N G E...

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Báo cáo khoa học: Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons ppt

Ngày tải lên : 22/03/2014, 21:20

... BM & Kim PY (20 00) Neuroprotective effect of green tea extract in experimental 380 15 16 17 18 19 20 21 22 23 24 25 26 27 ischemia-reperfusion brain injury Brain Res Bull 53, 743 – 749 Hong JT, ... 966, 22 9 24 5 Guillemin GJ, Cullen KM, Lim CK, Smythe GA, Garner B, Kapoor V, Takikawa O & Brew BJ (20 07) Characterization of the kynurenine pathway in human neurons J Neurosci 27 , 12 8 84 12 8 92 Finkbeiner ... QUIN 15 0 nM 12 10 0 10 20 30 40 50 60 70 80 90 10 0 QUIN Time (s) No QUIN B 10 .0 * * Amplitude 7.5 * 5.0 2. 5 0.0 0.0 15 0.0 550.0 QUIN conc (nM) 12 00.0 Fig QUIN induces Ca2+ in ux in human neurons...

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báo cáo khoa học: " Transcriptional control of anthocyanin biosynthetic genes in extreme phenotypes for berry pigmentation of naturally occurring grapevines" pptx

Ngày tải lên : 12/08/2014, 05:20

... 0. 01 4. 62 2 .26 4. 69 0. 04 0.06 2 .18 3. 32 0. 04 0.07 0. 04 0. 52 0 .22 1. 16 0. 02 0. 04 0.87 1. 03 0 .10 0.03 0. 02 2 .26 1. 53 9. 52 0.03 0.33 4. 62 1. 10 0 .16 0.03 0. 02 6 .26 3. 74 11 .00 0 .10 0. 92 5 .13 1. 63 ... 73.8 12 .9 86.7 87.0 0 .17 0. 01 0. 02 0. 02 0. 01 2. 90 1. 79 4. 91 0.07 0.06 2. 08 2. 78 0.07 0.03 0.07 1. 98 2. 44 11 .28 0 . 12 0 .15 2. 74 3.78 0 .18 0.07 0.03 0 .27 0 .16 0 . 14 0. 02 0.00 0. 01 1. 91 0 .11 0. 01 0. 01 ... 6 .2 76.0 16 .5 7 .4 0.9 12 .5 1. 1 73.0 12 .6 85.5 14 .5 85 .4 86 .4 7.5 93.9 86.5 5.8 78 .4 13 .4 8 .2 1. 8 8 .2 2 .2 66 .2 21 . 5 74. 4 25 .6 89.0 84. 3 8.6 92. 9 89.6 0.7 38.5 50.6 10 .9 4. 9 67.0 4. 4 5.3 18 .4 72. 3...

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unit 4- lesson 1 A1-2-4

Ngày tải lên : 10/10/2013, 06:11

... October 14 th, 2 010 Binh Thursday, October 14 th, 2 010 Hung Thursday, October 14 th, 2 010 Loan Thursday, October 14 th, 2 010 Hoa Thursday, October 14 th, 2 010 Mi Thursday, October 14 th, 2 010 Lan Binh ... England (X) x1 1) x2 7.00 Let’s play game 4) 4 .15 X o x3 7) Viet Nam (0) 01 1 .45 X o X o x4 x5 2) 8.30 5) 9 .40 X o X o x7 x9 03 04 x6 x8 02 3) 6.35 X 8) 11 .5 X o 05 06 07 6) 5 .25 9) 3 .10 08 09 Thursday, ... Hai 5 .45 6 .15 11 .30 10 .00 pm 3) Speaking: Hai gets up at 5 .45 everyday He goes to school at 6 .15 …… Thursday, October 14 th, 2 010 I) A1p 42 II) Vocabulary III) Grammar: IV)Further practise: 1) Mapped...

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Ma trận đề thi HK 1 lớp 2/4

Ngày tải lên : 08/11/2013, 00:11

... tròn kết 1/ Tính kết : 34 + 66 – 46 = ? a 54 b 55 c 53 d 64 b 61 c 51 d. 62 2/ Tìm x X – 43 = 18 a 60 3/ Số ? a -9 16 b 4/ Số? 24 kg – 13 kg + kg = a 15 c d kg b 16 c 25 d 26 5/ Tính : 48 dm + ... ……………………………… Học sinh lớp : 2 Đề thi kiểm tra cuối kì I Môn : Toán Năm học : 2 010 -2 011 Thời gian : ……… Điểm Nhận xét Chữ ký giám thị GT 1: GT 2: Số thứ tự Mật mã Chữ ký giám khảo GK 1: Mật mã GK 2: I ... học : 2 010 -2 011 Thời gian : …………… Điểm Nhận xét Chữ ký giám thị GT 1: Số thứ tự GT 2: Mật mã Chữ ký giám khảo GK 1: Mật mã GK 2: I Đọc thầm : 4 iểm A Đọc thầm : “Câu chuyện bó đũa ” B Dựa theo...

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Báo cáo y học: "Human articular chondrocytes express 15-lipoxygenase-1 and -2: potential role in osteoarthritis" pdf

Ngày tải lên : 09/08/2014, 14:20

... roles in tumor Available online http://arthritis-research.com/content /11 /2/ R 44 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 progression and survival Cancer Metastasis Rev 20 07, 26 :503- 5 24 Funk ... selection of new therapeutic targets Arthritis Rheum 20 01, 44 : 12 37 - 12 47 Burrage PS, Mix KS, Brinckerhoff CE: Matrix metalloproteinases: role in arthritis Front Biosci 20 06, 11 : 529 - 543 Page 10 of 12 (page ... suppress the production of TNF-α, a key cytokine in the pathogenesis of arthritis [19 ,20 ], and mediate the effects of the Thelper -2 cytokine IL -4 [ 21 , 22 ] The 15 -LOX metabolites 15 HETE and 13 -HODE...

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Báo cáo y học: "Dynamic features of the selective pressure on the human immunodeficiency virus type 1 (HIV-1) gp120 CD4-binding site in a group of long term non progressor (LTNP) subjects" pptx

Ngày tải lên : 13/08/2014, 05:21

... 20 09, 6 :4 3 41 K 1/ 15 K 5 / 14 R 4 / 14 V 4 /13 V 15 /15 V 10 / 14 346 Val 37.6% Ala 26 .8% Ser 11. 2% Phe 0 .2% Tyr 0% V A 5 /16 V 11 /16 V 15 /15 V 10 /10 A 4 /13 A 4 / 14 V K 6/8 K 5 / 14 R 1/ 8 E 1/ 8 Q 8 / 14 R 1/ 14 V ... A 12 /13 T T T K 15 /15 K 7 / 12 E 3 /13 K 12 / 12 E 4 / 12 T 1/ 12 K 10 /13 N 12 /15 Thr 91. 4% Ala 5.7% T T T 343 Asn 2. 4% lys 25 .9% Gln 40 .5% Glu 9.6% K K N 2 /13 N 14 /15 N 5 / 14 K 11 /13 Retrovirology 20 09, ... I(9.5) 2 918 993 II (10 .5) 3 318 735 III ( 12 ) 6850 640 I (11 .5) 12 00 795 II ( 12 .5) 20 00 720 III (13 .2) 30 34 527 I(8) 21 0 0 645 II (10 ) 12 00 657 III (13 ) 6393 625 I (10 ) 560 8 64 II (13 ) 10 6 926 III ( 14 ) 15 2 750...

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NMR study of the human NCK2 SH3 domains structure determination, binding diversity, folding and amyloidogenesis 1

Ngày tải lên : 14/09/2015, 14:09

... mediated by the individual SH3 were much weaker that that of the full length Grb4 The main binding region of DOCK180 was located at region 18 19 -18 36 In addition, two of the other weak binding sites ... and the actin polymerisation machinery (Aspenstrom P, 20 02) 15 1. 2 .1. 10 Nck2 interaction with wrch1, belonging to Cdc 42 subfamily Jan Saras recently identified that Wrch1 is one of the binding ... signalling protein, DOCK180, which interacts with Grb4 An SPR analysis showed that the second and third SH3 domain interact with the C-terminal of DOCK180 In terms of binding 12 affinity, interactions...

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A study on the techniques for the improvement to the teaching of oral skills in light of communicative english language teaching for junior high school teachers in quang ngai province part 1

Ngày tải lên : 07/11/2012, 14:41

... Organizing pair and group work Testing vocabulary Testing grammar Checking understanding Correcting students’ errors % 55 54 46 45 43 43 37 37 34 32 32 31 30 29 27 26 26 24 22 22 21 21 21 13 2. 6 .2. 5 ... teachers) 2. 6 .2 Findings and discussion 2. 6 .2 .1 Teachers' Personal Information The following graph shows the age of teachers: 50 40 30 20 10 12 % below 29 years 46 % 30-39 years 41 % 40 -49 years 1% 50+ ... or less 35 30 25 20 15 10 3 %2- years 16 % 2- 5 years18% 6 -10 years 27 % 11 -15 years 33% 16 -20 years Figure 2. 6 .2 .1. 2 No years of ELT experience 3% 20 + years 10 Approximately one third ( 31% ) have received...

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