drugs medicaments and biological substances causing adverse effects in therapeutic use
Báo cáo khoa học: " Evaluation of adverse effects in tamoxifen exposed healthy female dogs" doc
... rate, and respiratory rate, inspection of mucosal membranes and skin, inspection and palpation of lymph nodes, joints, external genitalia, and mammary glands, and palpation of the abdominal cavity ... 2Veterinary Teaching Hospital, College of Veterinary Medicine, Federal University of Minas Gerais (UFMG), Brazil 3Department of Veterinary Clinical Medicine and Surgery, College of Veterinary ... Acta Veterinaria Scandinavica 2010, 52:67 http://www.actavetscand.com/content/52/1/67 A dose of 0.5 mg/kg BW was suggested in another study to minimize adverse effects [10] Considering the lack...
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báo cáo khoa học: "The relationship between baseline Organizational Readiness to Change Assessment subscale scores and implementation of hepatitis prevention services in substance use disorders treatment clinics: a case study" pdf
... doing routine laboratory testing at intake, adding hepatitis B and C testing to the routine testing panel may be a relatively easy change in practice compared to negotiating the availability and ... implementation clinics (defined as clinics receiving an implementation score of or greater at the final followup available) and low implementation clinics (defined as clinics receiving an implementation ... suggests that these clinics were already motivated to improve healthcare practices before attending the LHI training Ongoing research includes clinics that are mandated to attend training, which will...
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Tài liệu OXIDATIVE STRESS – MOLECULAR MECHANISMS AND BIOLOGICAL EFFECTS doc
... aminoguanidine, pyridoxamine, drugs used in the treatment of type diabetes such as metformin and pioglitazone, angiotensin receptor blockers and inhibitors of angiotensin converting enzyme, amino ... enormous interest and intensive research in this field that prompted us to develop this book idea In addition to interest in basic science, there is also a growing interest in medicine, agriculture and ... Finally, their signaling role was disclosed at the beginning of 1990, initially in coordination of response to oxidative stress, and further involved in hormone effects in plants and animals (Semchyshyn,...
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Tài liệu BIOCHEMICAL TARGETS OF PLANT BIOACTIVE COMPOUNDS A pharmacological reference guide to sites of action and biological effects doc
... stereoisomer of cinchonidine), hydroquinidine (quinotidine), quinine and quinidine (P-quinine), these compounds all having a quinuclidinemethanol (l,4-ethylpiperidinylmethanol) substituent Quinine is also ... iodothyronine deiodinase inhibitors (fisetin, kaempferol and morin); NADH and succinate dehydrogenase inhibitors (fisetin and myricetin); and protein kinase inhibitors (fisetin, galangin, isorhamnetin, ... anthocyanidins include apigeninidin, delphinidin, hirsutidin, luteolinidin, malvidin, pelargonidin, peonidin and petunidin, the structural variations arising from differing patterns of hydroxy and methoxy...
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Tài liệu The Acquisition of Drugs and Biologics for Chemical and Biological Warfare Defense - Department of Defense Interactions with the Food and Drug Administration doc
... a continuing dependent relationship that involves three types of interactions: licensing CBW drugs and biologics, especially vaccines; using Investigational New Drugs in military combat (and other ... molecules (drugs) Second, industry makes a deep investment in education and training (E&T) of its personnel in manufacturing At Merck Manufacturing Division, for example, formal training includes ... acquisition of drugs and biologicals for CBW defense: licensing drugs and biologics for military uses, especially CBW defense; using drugs and biologics classified by FDA as INDs in certain combat...
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Báo cáo khoa học: Structural and biological effects of a b2- or b3-amino acid insertion in a peptide Application to molecular recognition of substance P by the neurokinin-1 receptor ppt
... and w and were subsequently refined by varying /, w angles in intervals of 10° and setting h angle to ) 60 ± 10° and 60 ± 10° Each /, h, and w-value was fixed by applying a harmonic potential and ... Regarding the minor binding site NK-1m, SP and [Pro9]SP show a 10-fold increase in affinity compared to their affinity for the NK-1M binding site, with Ki in the subnanomolar range (0.13 nM) and ... time NK-1M and NK-1m binding sites were not differentiated) The amide bond between residues and 10 is not involved per se in any stabilizing interaction within the NK-1 receptor because [Gly9(wCH2CH2)(S)Leu10]SP...
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Milk Thistle: Effects on Liver Disease and Cirrhosis and Clinical Adverse Effects doc
... liver and gallbladder disorders, including hepatitis, cirrhosis, and jaundice, and to protect the liver against poisoning from chemical and environmental toxins, including snake bites, insect stings, ... silybin (also known as silybinin or silibinin), silychristin (or silicristin), and silydianin (also silidianin).16 Silybin is the most prevalent of the three (about 50 percent of silymarin) and ... thistle Adverse Effects Adverse effects associated with oral ingestion of milk thistle include gastrointestinal problems (e.g., nausea, diarrhea, dyspepsia, flatulence, abdominal bloating, abdominal...
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Encyclopedia of Mind Enhancing foods, drugs, and nutritional substances pot
... in the diet are alanine, arginine, asparginine, aspartic acid, carnitine, cysteine, cystine, glutamic acid, glutamine, glycine, hydroxyproline, ornithine, proline, serine, and tyrosine The line ... trembling in the hands, and swelling in the feet and legs Rare side effects include a rash or itchy skin, sore throat, fever, abdominal pain, nausea, vomiting, unusual bruising or bleeding, jaundice, ... invariably induces vomiting and an hour or two of nausea The vomiting and nausea can usually be minimized by fasting or taking Dramamine beforehand and remaining perfectly still during the visions...
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báo cáo hóa học:" Women''''s quality of life is decreased by acute cystitis and antibiotic adverse effects associated with treatment" pptx
... difference in improvement of QOL by treatment assignment (Figure 5) Adverse effects Seventy-six of the 146 patients included in the analysis reported 94 adverse events Gastrointestinal effects and vaginitis ... ciprofloxacin and nitrofurantoin, respectively Clinical outcomes Clinical cure rates did not differ by treatment with 88, 82 and 87% of patients treated with TMP/SMX, ciprofloxacin and nitrofurantoin, ... commonly occurring adverse events, accounting for 26 (28%) and 25 (27%) of the effects, respectively Headache (12% of patients) and other central nervous system effects such as dizziness (5%) were...
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Báo cáo hóa học: " Underlying reasons of the controversy over adverse effects of Bt toxins on lady beetle and lacewing larvae" potx
... ago revealing these shortcomings for green lacewing larvae and documenting that Bt toxins - both of microbial origin and of plant-origin - caused significant lethal effects in green lacewing larvae ... organisms Inconsistent evaluation standards and asymmetrical levels of scrutiny applied to studies reporting significant adverse effects compared to those finding no adverse effects are described using ... standards and asymmetrical levels of scrutiny are being applied to studies reporting adverse effects of Bt toxins expressed in genetically modified [GM] crops on nontarget organisms that continue...
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OXIDATIVE STRESS – MOLECULAR MECHANISMS AND BIOLOGICAL EFFECTS doc
... aminoguanidine, pyridoxamine, drugs used in the treatment of type diabetes such as metformin and pioglitazone, angiotensin receptor blockers and inhibitors of angiotensin converting enzyme, amino ... enormous interest and intensive research in this field that prompted us to develop this book idea In addition to interest in basic science, there is also a growing interest in medicine, agriculture and ... Finally, their signaling role was disclosed at the beginning of 1990, initially in coordination of response to oxidative stress, and further involved in hormone effects in plants and animals (Semchyshyn,...
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Báo cáo y học: "Innovative combination strategy to enhance effect and diminish adverse effects of glucocorticoids: another promise" pot
... rats, and mice are not patients and the glucocorticoid mechanisms leading to effects and adverse effects are manifold Ultimately, the proof of the pudding is in the eating Comparative clinical ... with inflammatory and immunosuppressive activity and with adverse effects, respectively For instance, hypopituitarypituitary-adrenal axis suppression and increased risk of infection are linked ... numbers of patients and regular assessments of predefined beneficial effects and adverse effects in a standardized way are warranted This is the next challenge Competing interests The authors...
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Báo cáo y học: "Relative effectiveness and adverse effects of cervical manipulation, mobilisation and the activator instrument in patients with sub-acute non-specific neck pain: results from a stopped " ppt
... up point Pain decreased by points in the Activator group, points in the manipulation group, and points in the mobilisation group A reduction in pain of at least points is considered a clinically ... variables and used to compare differences between and within the groups This instrument is commonly used in research and has been shown to be reliable and valid [64-66] The 11-point numerical rating ... therapeutic interventions used in manual therapy and would allow generalisability to standard chiropractic and osteopathic care Comparison with other studies Our finding of mobilisation causing more adverse...
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Tài liệu Drugs: Photochemistry and Photostability doc
... Range in Photostability Testing of Pharmaceuticals E Bovina, P De Filippis, V Cavrini and R Ballardini 305 Subject Index 17 Photochemistry of Drugs: An Overview and Practical Problems Angelo Albini ... pyrazolones remains the same in the solid state.51However, in the latter case different processes may be involved, as with aminopyrine for which the main reaction in the solid is type I (i.e involving addition ... rather than exhaustive The drugs are grouped according to the following broad therapeutic categories: - anti-inflammatory, analgesic and immunosuppressantdrugs; - drugs acting on the central nervous...
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Tài liệu Gulf War and Health: Volume 4. Health Effects of Serving in the Gulf War docx
... public, and the scientific and engineering communities The Council is administered jointly by both Academies and the Institute of Medicine Dr Ralph J Cicerone and Dr Wm A Wulf are chair and vice ... to determine exposure (see Chapter 2) Petroleum products, including diesel fuels, were also used to suppress sand and dust, and petroleum fuels were used to aid in the burning of waste and trash ... used such weapons in fighting Iran and in attacks on the Kurdish minority in Iraq Military leaders feared that the use of such weapons in the gulf could result in the deaths of tens of thousands...
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Tài liệu MIT Joint Program on the Science and Policy of Global Change: Effects of Air Pollution Control on Climate pdf
... carbon, and SOx both individually and combined in two ways These caps can lower ozone causing less warming, lower sulfate aerosols yielding more warming, lower OH and thus increase CH4 giving more ... slightly increase OH (due to lower SO2 which is an OH sink) Capping of NOx leads to decreases in O3 and OH and an increase in CH4 (caused by the lower OH which is a CH4 sink) The CO and VOC cap increases ... leadership in understanding scientific, economic, and ecological aspects of this difficult issue, and combining them into policy assessments that serve the needs of ongoing national and international...
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Tài liệu Báo cáo khoa học: How disorder influences order and vice versa – mutual effects in fusion proteins containing an intrinsically disordered and a globular protein docx
... (2005) The intrinsically disordered C-terminal domain of the measles virus nucleoprotein interacts with the C-terminal domain of the phosphoprotein via two distinct sites and remains predominantly ... example, in KNR4, a 505 residue yeast protein involved in the coordination of cell wall synthesis and cell growth [18], the nucleoprotein and phosphoprotein from measles and Sendai viruses [19,20] and ... (2008) Mapping alpha-helical induced folding within the intrinsically disordered C-terminal domain of the measles virus nucleoprotein by site-directed spin-labeling EPR spectroscopy Proteins 73,...
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Tài liệu Báo cáo khoa học: Design, structure and biological activity of b-turn peptides of CD2 protein for inhibition of T-cell adhesion ppt
... 10% (w/v) heatinactivated fetal bovine serum and 100 mgÆL)1 of penicillin/ streptomycin Caco-2 cells were maintained in minimum essential medium-a containing 10% (w/v) fetal bovine serum, 1% ... by binding to CD58, hence inhibiting CD2–CD58 interaction Therefore, docking studies of peptides to CD58 protein were carried out in order to understand peptide–protein interactions by using ... directly interrupt the binding mechanism of CD2–CD58 Inhibition of cell adhesion involves interrupting the interaction of key residues at the protein– protein interface If we consider hydrogen bonding...
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