... these agencies Region No IIIIII IV V VI VII VIII IX X XI XII XIII XIV XV 1.2 Name of States/Union Territories in the Region Andhra Pradesh and A & N Islands Tamil Nadu, Lakshdweep and Pondicherry ... deliveries took place in health xix institutions In other districts- from Kerala and Chennai from Tamil Nadu- institutional deliveries constituted 99 percent of the total deliveries In India 63, ... district level indicators The weight is the proportion of the district population in the total population of the state ∑ Wi CPR = CPR (i ) Each district level indicator i is assigned a weight wi...
... Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH)-Good Clinical Practice (GCP)-registered phase I/ II clinical trial of rh-HGF As this application is the first clinical ... renal involvement, including serum creatinine and histological findings A phase I/ II clinical trial for patients with acute liver failure Overview This single-arm, open-labeled, and dose-escalation ... confirmed reversibility of renal toxicity through additional preclinical studies In this clinical trial, rh-HGF was administered intravenously for 12 to 14 days, and severe side effects and Ido...
... maximum of Grade Iand 26% (n = 10) Grade II during RT None developed a grade III/ IV acute GU toxicity Acute GU toxicity reached its maximum in weeks andand resolved within weeks after RT in ... until now (Grade II toxicity) No Grade III toxicity was seen with a median follow up of 20 months At 24 and 36 months there were still respectively 3/10 and 2/6 patients with Grade I toxicity ... in their randomized trial somewhat higher figures of grade II (40%) and grade III (8%) acute GU toxicity in the H-IMRT arm (70.2 Gy in 26 fractions of 2.7 Gy) although PTV margins were slightly...
... of IgG positive antibody secreting cells in the lamina propria [21] The weak correlation of IgG antibodies in IS to serum IgG is consistent with this dual origin of bronchial IgG antibodies IgA ... 8:57 remains to be shown whether the OprF-OprI vaccine can be effective in patients with CF and other conditions Recent data of a phaseIII clinical trial with CF patients evaluating a bivalent ... OprFOprI vaccine Recent data of a phaseIII clinical trial with a flagella vaccine support both the promise of protein based vaccines andthe need for further optimization of the vaccine strategy...
... overwhelming in some reports, while in others most of theinformation is implicit The complexity of the accidents described ranges from simple accidents with only one vehicle to multiple collisions with ... reorganizes them and discards the temporal loops The initial step of the loop resolution assigns each link with a score This score is created by the decision trees and is derived fromthe C4.5 metrics ... semantics will be a proposition paired with a point or interval in time during which the proposition is true • Relations and Quantities They describe specific features of objects and events and...
... for further clinical evaluation because the toxicity increased with higher doses in the prior phase I/ II clinical trials, whereas there was evidence of reproducible immune activation at this dose ... study and performed the statistical analysis AK participated in the study design and coordination SDG participated in the study design and coordination OK participated in the study design and coordination ... participated in the study design and coordination TLW carried out and interpreted the immunoassay and drafted portions of the manuscript describing the assays WG participated in the design of the...
... subsided within hour (the fourth infusion was not administered to this patient) Overall, the infusions were administered in a median infusion time Figure Autoantibodies There were no changes in the ... regeneration of glandular tissue, suggesting the need for pre- and post-therapy biopsies of minor salivary glands Additional findings in terms of statistically significant improvement from baseline in ... mechanism of action is believed to be the downregulation of the BCR, with mechanisms of action differing from rituximab (by CD22 phosphorylation and BCR effects via immobilised Ig crosslinking) [18,21]...
... Appendix - RTOG late toxicity scale RTOG GRADE IIIIII IV None Slight epithelial atrophy; minor telangiectasia (microscopic hematuria) Moderate frequency; generalized telangiectasia; intermittent ... Arcangeli G, Saracino B, Gomellini S, et al: A Prospective PhaseIII Randomized Trial of Hypofractionation Versus Conventional Fractionation in Patients With High-Risk Prostate Cancer International ... published data fromphase I/ II trial not have sufficient follow-up to draw conclusions Table Acute urinary and rectal toxicity after prostate EBRT RTOG GRADE IIIIII IV GENITOURINARY On-treatment...
... 1) Where PriorPInfy+1 is the prior probability of infection in year y+1, PostInfy is the posterior probability of infection in year y and PIntro y+1 is the probability of introduction in year y+1 ... Positive Positive Negative Negative Positive Positive Terminal nodes Negative outcome Positive outcome PR TAKE SAMPLE Negative Negative Positive Positive Negative Negative Positive Negative Positive ... Infection node Detection nod MEAT INSPECTION Negative Negative Positive SCT Negative Positive Negative PCR Positive Negative Negative Positive Positive SCT Positive PCR Negative Negative Positive...
... h i viết câu h i trả l i) ĐỀ KIỂM TRA GIỮA HỌC KỲ I MÔN SINH HỌC LỚP Đề số Th i gian làm b i: 45 phút Câu 1: ( i m) Cấu tạo nơron thần kinh? Chức nơron? Câu 2: (2 i m) Tìm đặc i m chứng minh ... Câu ( i m) Để xương phát triển cân đ i cần làm ? ( Không gập, viết vẽ vào đề kiểm tra, làm câu h i viết câu h i trả l i) ĐỀ KIỂM TRA GIỮA HỌC KỲ I MÔN SINH HỌC LỚP Đề số Th i gian làm b i: 45 ... i m) Để chống cong vẹo cột sống lao động học tập ph i ý i m ? ( Không gập, viết vẽ vào đề kiểm tra, làm câu h i viết câu h i trả l i) ĐỀ KIỂM TRA GIỮA HỌC KỲ I MÔN SINH HỌC LỚP Đề số Th i gian...
... the binding between decorin and collagens or their CNBr peptides is quite sensitive to the ionic strength of the buffer, suggesting an ionic character of the binding The main decorin region implicated ... of their positive charge eliminates the interaction On the contrary, the chemical modification preserving the ionic character modulates the binding to decorin This leads to a differential behaviour ... binding of chemical modification of Lys and Hyl side chains of collagens and peptides Derivatizations that eliminate the positive charge of Lys/Hyl eliminate the binding to decorin, whereas the binding...
... unified modes I, IIandIII stress intensity factors, KIθ/KIC, KIIθ/KIIC and KIIIθ/KIIIC, respectively (Lo et al., 2000) Theapplication of the finite element (FE) method to LEFM, and numerical methods ... data from mixed mode IIIIII loading, as shown in Figure 1.6 Modes IandII crack tip loading conditions were created in the specimen by subjecting it to an axial load, while mode III crack tip ... Depending on the values of h and a, it is possible to induce mixed mode I II, I III, or III III, loading at the fronts of the corresponding main notches By using four failure planes in different...
... I, IIandIII fracture toughness, KIC, KIIC and KIIIC, respectively, of the test material The evaluation of KIC and KIIC will be dealt with in the following discussion, while that of KIIIC will ... K IC = K I0 ⋅ FIC , (4.1) K IIC = K II0 ⋅ FIIC , (4.2) while for pure mode II loading, where KI0 and KII0 are the respective stress intensity factors obtained from K-calibration curves shown in ... Modes IandII Fracture Testing Before verification of the proposed mixed mode IIIIII fracture criterion, given by foregoing equation (2.80) of §2.4, it would be necessary to evaluate the pure...
... loading (in which α=90° and α=0, respectively), as K IC = K I0 ⋅ FIC (4.3) K IIIC = K III0 ⋅ FIIIC (4.4) andThe respective stress intensity factors, KI0 and KIII0, were obtained fromthe K-calibration ... are depicted in the plot between the normalized unified pure mode IandIII stress intensity factors, KIθ /KIC and KIIIθ /KIIIC, respectively, of Figure 4.29 The figure also shows the unified fracture ... concentration Figure 4.19 shows theapplication of mixed mode I- III loading at an angle of α=45° The main advantage of the test configuration is that the entire mixed mode I- III 95 F le α ang ing load...
... of beam group D Figure 4.39 Failure of mixed mode I – II – III fracture test specimens 133 KIIθ KIθ KIIIθ ( KIC )2+ ( KIIC ) + ( KIIIIC )=1 2 √(K II θ / KIIC)2 + (KIIIθ / KIIIC) 1.0 0.8 0.6 0.4 ... as K I = K I0 ⋅ FC , (4.7) K II = K II0 ⋅ FC (4.8) K III = K III0 ⋅ FC , (4.9) and where KI0, KII0 and KIII0 are the stress intensity factors, due to unit loading, obtained according to the ... testing machine In order to achieve differing mode I/ mode IIand mode I/ mode III loading ratios, each beam group (according to §4.4.1) was subjected to various loading cases, as depicted in Figure...
... đ i chiếu v i tiêu để xác định xã thuộc khu vực I, IIIII (theo biểu 02 Thông tư số 01/2012/TTUBDT); đồng th i tổ chức họp thông qua kết xác định thôn đặc biệt khó khăn xã thuộc khu vực I, II III; ... biệt khó khăn xã xếp xã vào khu vực I, II III; trình UBND tỉnh kết xét duyệt thôn đặc biệt khó khăn danh sách xã thuộc khu vực I, IIIII (theo biểu 04, 05 Thông tư số 01/2012/TT-UBDT) kèm Biên ... Rà soát đ i chiếu v i số liệu, t i liệu thực trạng kinh tế - xã h i để xác định thôn đặc biệt khó khăn xã thuộc khu vực I, II, III Th i gian thực xong trước ngày 20/01/2013 Tổ chức i u tra xét...
... natri hiđroxit hợp chất ion C glixerol chất lỏng, natri hiđroxit chất rắn D glixerol chất không i n li, natri hiđroxit chất i n li Câu 2: Các mu i, axít, hiđroxit tan chất i n li vì: A chúng ... A orbital s v i orbital p tạo thành orbital lai hoá sp2 B orbital s v i orbital p tạo thành orbital lai hoá sp2 C orbital s v i orbital p tạo thành orbital lai hoá sp2 D orbital s v i orbital ... trúc C góc không gian D góc hóa trị Câu 6: Liên kết hóa học ion đợc g i A liên kết anion cation B liên kết ion hóa C liên kết tĩnh i n D liên kết ion Câu 7: Liên kết ion khác liên kết cộng hóa...
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