... x-rays are used to treat cancer.
24
Chemotherapy
Chemotherapy uses drugs to kill cancer cells. It may be
given to women with Stage I, II, III, or IV breast cancer.
Chemotherapy may be given ... lymph nodes.
Stage IIIB
e breast tumor can be any size, and it has grown into
the chest wall or the skin of the breast. e breast may be
swollen or the breast skin may have lumps.
e cancer may ... problems that can result from cancer treatment
■ A new breast cancer
Checkups usually include an exam of the neck, underarm,
chest, and breast areas. Since a new breastcancer may
develop, you...
... Pharmacopro-
teomic analysis of prechemotherapy and postchemotherapy
plasma samples from patients receiving neoadjuvant or adju-
vant chemotherapy for breast carcinoma. Cancer 2004,
100:1814-1822.
40. ... in personalized therapy for
breast cancer. Clin Cancer Res 2008, 14:8019-8026.
53. Hayashi S, Yamaguchi Y: Estrogen signaling pathway and hor-
monal therapy. BreastCancer 2008, 15:256-261.
54. ...
patterns specific for healthy persons and breastcancer
patients
At first we compared the serum proteome patterns of 104
healthy women and 92 early stagebreastcancer patients.
Spectral components...
... Pharmacoproteomic analysis of
prechemotherapy and postchemotherapy plasma samples from
patients receiving neoadjuvant or adjuvant chemotherapy for breast
carcinoma. Cancer 2004, 100:1814-1822.
32. ... usually
exceeds 80%). Primary therapy for breastcancer is usually
based on surgery, either radical or breast- conserving
mastectomy. However, even in early stagecancer some
patients are at high risk ... analysis in diagnostics of breast cancer. These
works identified serum (or plasma) proteome patterns
specific for patients with breastcancer at either early or
late clinical stages [19-29]. Different...
... overall, women with
breast cancer fare well by 12 months following diagno-
sis; however, interventions are needed to improve breast
cancer- related concerns among all women with breast
cancer and physical ... co-morbid-
ities (other than breast cancer) , while non-urban breast
cancer survivors were more likely to be sedentary and/
or have two or more co-morbidities (other than breast
cancer) , when compared ... well-being subscale. Women with breast
cancer also completed 13 questions on breast cancer
concerns and arm morbidity (FACT-B+4), with total
scores from 0-52 for the breastcancer concerns sub-
scale,...
... first-line chemotherapy in this study seems to indicate that
this strategy should be recommended in patients with an ER or PgR positive tumour.
Key words: Breast cancer; maintenance treatment; chemotherapy; ... treated for
metastatic breastcancer in 4 French cancer centres. The
diagnosis of metastasis was made between 1992 and
2002. A total of 772 patients received first-line
chemotherapy [4]. Because ... HORMONAL TREATMENT IMPROVES PROGRESSION FREE
SURVIVAL AFTER A FIRST LINE CHEMOTHERAPY IN PATIENTS WITH
METASTATIC BREASTCANCER
Armelle Dufresne
1
, Xavier Pivot
2
, Christophe Tournigand
3
,...
... now considered a standard of care in early breast cancers with
N0 axillae; however, its role in locally advanced breastcancer (LABC) after neo -adjuvant chemotherapy (NACT) is
still being debated. ... advanced breast cancers (LABC).
The current treatment guidelines for LABC focus upon
multimodality approach i.e. neo-adjuvant chemotherapy
(NACT)followedbysurgeryandadjuvanttherapiesin
the form of chemotherapy, ... the effects of adjuvant chemotherapy [4-7].
More recently, the indications for NACT have also been
extended to selected patients with an early staged dis-
ease to allow breast conserving surgery...
... carcinoma of the breast and 40,000 women die of
the disease every year [2]. Although breastcancer is cur-
rently the second most commo n cancer among Indian
women (19%) after cervical cancer (30%), ... the urban
cancer registries of Delhi and Mumbai it has rapidly
overtaken cervical cancer in frequency. In India majority
of breastcancer cases (30-50%) present at locally
advanced stage [3] ... chemotherapy in
locally advanced breastcancer patients. Additional work
is necessary to elucidate the specific mechanisms by
which the androgens and AR influences breast cancer
cells proliferation...
... therapy versus conventional postopera-
tive whole -breast radiotherapy after breast- conserving
surgery for the management of early -stage invasive breast
cancer (a trial update). Amer J Surg 2007, 194:507-510.
19. ... IORT is needed to establish clinical
efficacy and safety for patients with early -stage breast cancer.
Background
Several large randomized trials with extended follow-up
have shown that breast ... XB in the outpatient treatment
of early -stage breastcancer patients were recently pre-
sented at the American Society of Clinical Oncology
(ASCO) BreastCancer Symposium. Treatment with XB
was...
... the use of breast- conserving therapy
in stage I and II breast carcinoma. J Clin Oncol 2001, 19:2254-2262.
4. Arthur DW, Vicini FA: Accelerated partial breast irradiation as a part of
breast conservation ... study comparing
breast- conserving surgery with radical mastectomy for early breast
cancer. N Engl J Med 2002, 347:1227-1232.
6. Morrow M: Rational local therapy for breast cancer. N Engl J ... accelerated partial breast
irradiation. BreastCancer 2008, 15:101-107.
27. Powell SN: The radiobiology of accelerated partial breast irradiation. In
Accelerated partial breast irradiation:...
... 193 69 53 59
Cancer site/
staging
All Tonsil
All stage 4
Oropharynx
54%
Stage4 60%
Oropharynx
53%
Stage 4 81%
Oropharynx
35%
Stage 4 83%
Oropharynx 44%
Stage 4 96%
All Oropharynx
Stage 4 65%
Oropharynx
62%tongue
base
Stage ... performed stratified by tumour stag e
(T stage) , nodal stage (N stage) and treatment (induc-
tion chemotherapy followed by concurrent chemora-
diotherapy or induction chemotherapy followed by
radiotherapy ... docetaxel in unresectable head and
neck cancer. N Engl J Med 2007, 357(17)
:1695-704.
14. Cancer Research UK Cancer Statistics. [http://info.cancerresearchuk.org/
cancerstats/types/oral/incidence/],...
... detect breast cancer. Clin Chem 2002;48(8):
1296–1304
27. Mathelin C. Cromer A, Wendling C, Tomasetto C, Rio MC:
Serum biomarkers for detection of breast cancers: a prospective
study. BreastCancer ... patients
with pT1–2 breast cancer. Anticancer Res 2004; 24(5):
3221–3224.
11. Stein RC, Zvelebil MJ: The application of 2D gel-based prote-
omics methods to the study of breast cancer. J Mammary ...
studies is needed to consider of the efficacy of Bc1 and Bc2 in early diagnosis of the BC.
Key words: BreastCancer diagnosis, Serum Biomarkers, Bc1, Bc2, and Bc3
INTRODUCTION
Breast cancer (BC)...