does it still have a role in the management of heart failure

Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf

Ngày tải lên : 18/02/2014, 04:20

... we have identiﬁed the GRASP55 binding site in the ICD of MT1-MMP, as well as the GRASP55 domains involved in the interaction with MT1-MMP ICD We also describe the GRASP55 interaction with the ... complex containing MT1MMP and furin, and the expression of a catalytically inactive dominant negative furin construct affected the processing of pro-MT1-MMP Taken together, these data reveal a new ... representing a speed increase of ·40 Statistical analysis was performed using the graphpad prism, version (GraphPad Software, Inc., San Diego, CA, USA) Statistical signiﬁcance was calculated using...

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Báo cáo khoa học: "Does the surgeon still have a role to play in the diagnosis and management of lymphomas?" docx

Ngày tải lên : 09/08/2014, 07:21

... therapeutic approach There is a question as to the accuracy of FNAC in the diagnosis of lymphomas as the tumours often contain malignant and reactive elements and the FNAC may only have sampled the reactive ... incidence in Wales with a ratio of 1:4 [1] Table 1: Anatomical location of lymphomatous lymph nodes (n = 62) Anatomical location Number of cases Cervical Inguinal Axillary Intra-abdominal Supraclavicular ... endoscopy and laparoscopy in obtaining biopsy material The advent of endoscopic ultrasound-guided FNAC allows targeting of mediastinal and intra-abdominal lymphadenopathy, which can be performed without...

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Tài liệu Telecommuting: will it change the world? Telecommuting will have major effects in the worlds of work pdf

Ngày tải lên : 25/01/2014, 19:20

... have many skills that compensate for the decline in the ability of the brain to grasp and remember new material They can organize their learning by setting times for reading or practice They can ... on animals, especially with the huge database of knowledge and modern computer models They also are worried that many animal tests are ineffective, pointing out that any drugs have had to be withdrawn ... as the family’s religion or language may not even be available in the school Other parents may disagree with the aims of the school curriculum, preferring for academic, social or cultural reasons...

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Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is speciﬁcally induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf

Ngày tải lên : 21/02/2014, 01:21

... Onion arabinogalactan consists of 99% D-galactose and 0.3% L-arabinose and is predominantly linear Potato arabinogalactan consists of 86% D-galactose and 6.6% L-arabinose, while soy arabinogalactan ... activity of GALA with different arabinogalactans was measured in duplicate by HPAEC and MALDI-TOF MS after incubation of mgÆmL)1 of potato, onion and soy arabinogalactan with 1.33 lgÆmL)1 GALA at ... disappear in time, suggesting the presence of an arabinose-releasing activity in the GALA preparation However, no a- 1-,3-L-arabinofuranosidase activity could be detected using PNP -a- L-arabinofuranoside...

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Báo cáo khoa học: Acylation of lysophosphatidylcholine plays a key role in the response of monocytes to lipopolysaccharide ppt

Ngày tải lên : 31/03/2014, 01:20

... (Kirkegaard and Perry, Gaithersburgh, MD, USA) per well The plate was incubated in the dark for 20 and the reaction stopped by the addition of 50 lL of 0.5 M sulfuric acid The plate was read on a Labsystems ... conﬁrms that IFN-c can increase the activity of an enzyme, LPCAT, that participates in the rapid turnover of PtdCho Lysophospholipid acyltransferases maintain membrane lipid composition and the asymmetrical ... peritoneal macrophages stimulated with the endomembrane Ca2+-ATP-ase inhibitor thapsigargin [34] They assumed this effect to be due to inhibition of CoA-independent acyltransferase activity as...

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Báo cáo hóa học: " Targeting the inflammation in HCV-associated hepatocellular carcinoma: a role in the prevention and treatment" pptx

Ngày tải lên : 18/06/2014, 16:20

... some alterations (i.e increased levels of aspartate transaminase, alanine transaminase, alkaline phosphatase, acid phosphatase, lactate dehydrogenase, gamma-glutamyltransferase, 5’-nucleotidase, ... via TRIF (TIRdomain-containing adapter-inducing interferon-b) joining the RIG-I/MDA5 pathway In the other pathway, TLR7 senses single-strand HCV RNA and via the MyD88 adaptor protein activates ... 124(11):2520-7 90 Jagan S, Ramakrishnan G, Anandakumar P, Kamaraj S, Devaki T: Antiproliferative potential of gallic acid against diethylnitrosamineinduced rat hepatocellular carcinoma Mol Cell Biochem...

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Báo cáo khoa học: "SemiPro-inflammatory cytokines play a key role in the development of radiotherapy-induced gastrointestinal mucositis" pptx

Ngày tải lên : 09/08/2014, 08:22

... 5’-GTGCATCATCGCTGTTCATACA TNF Forward: 5’-GTGATCGGTCCCAACAAG-3’ Results 71 X66539 Reverse: 5’-AGGGTCTGGGCCATGGAA-3’ b actin Forward: 5’-AGGCCAACCGTGAAAAGATG-3’ 101 NM_031144 Reverse: 5’-ACCAGAGGCATACAGGGACAA-3’ ... weeks of radiotherapy Staining was variable between the basal and apical regions of the crypts and did not significantly change of the course of radiotherapy (Data not shown) IL-6 IL-6 staining was ... that had received no radiotherapy There was an increase in protein expression of TNF after radiotherapy, particularly after 22.5 Gy and 30 Gy as indicated by the arrow, although the staining was...

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Báo cáo y học: "Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration" ppt

Ngày tải lên : 09/08/2014, 10:20

... TCA CCA CCA C 3' 99.77% ADAMTS 5' GGA CCT ACC ACG AAA GCA GAT C 3' 5' FAM – CCC AGG ACA GAC CTA CGA TGC CAC C – TAMRA 3' 5' GCC GGG ACA CAC GGA GTA 3' 99.74% ADAMTS 5, a disintegrin and metalloprotease ... areas: the NP, inner AF (IAF), and outer AF (OAF) Regions situated at the junction of IAF and OAF or of NP and IAF were not included in the analysis Within each area, five fields of view were analysed ... samples are as described in (a) Data are shown as average MTL ± standard error of the mean (SEM) for each disease state (c) Quantification and localisation of p16INK 4a immunopositivity in human...

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báo cáo khoa học: " The transcription factor PHR1 plays a key role in the regulation of sulfate shoot-to-root flux upon phosphate starvation in Arabidopsis" potx

Ngày tải lên : 11/08/2014, 11:21

... 10:78 Tomatsu H, Takano J, Takahashi H, Watanabe-Takahashi A, Shibagaki N, Fujiwara T: An Arabidopsis thaliana high-affinity molybdate transporter required for efficient uptake of molybdate from ... M, Hawkesford MJ, Saito K: The roles of three functional sulphate transporters involved in uptake and translocation of sulphate in Arabidopsis thaliana Plant J 2000, 23:171-182 Kataoka T, Hayashi ... sulfate transport was expressed as the percentage of radioactivity located in the roots over the total amount of radioactivity in the whole plant Phosphate and sulfate measurements Anion measurements...

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báo cáo khoa học: " Does harm reduction programming make a difference in the lives of highly marginalized, at-risk drug users?" pot

Ngày tải lên : 11/08/2014, 20:20

... Transitional case management, including facilitation of access to HIV counseling and testing, primary care, intensive case management, drug treatment, housing, and mental health and nutritional services; ... people at NYHRE who logistically set up of the research and assisted with data analysis: Eddie Rivera and Ken Teasley, Data Coordinator We also appreciate the work of AED staff and consultants: Kathryne ... services can receive them Rather than having a single entry point, clients can join the program at any part of the organization, including the formal offices, the street-side service delivery sites,...

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Báo cáo y học: " Th2 cytokines and asthma Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists" pot

Ngày tải lên : 12/08/2014, 18:20

... and the induction of VCAM-1 are activities shared with the related cytokine IL-13 reports Animal studies demonstrating the role of IL-4 in asthma Neutralizing IL-4 with anti-IL-4 antibodies in ... heterodimer are required to initiate intracellular signaling (b) The sIL-4R consists of the extracellular portion of IL-4Rα It retains the ability to bind IL-4 with high affinity and high specificity and ... Mitsuyasu H, Izuhara K, Mao XQ, Gao PS, Arinobu Y, Enomoto T, Kawai M, Sasaki S, Dake Y, Hamasaki N, Shirakawa T, Hopkin JM: α Ile50Val variant of IL4Rα upregulates IgE synthesis and associates...

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Báo cáo khoa học: "Do statins have a role in preventing or treating sepsis" pptx

Ngày tải lên : 12/08/2014, 23:21

... modality after the onset of sepsis-induced organ dysfunction Data in humans are lacking In a prospective observational cohort study [18] it was found that prior statin therapy is associated with ... effects of statins may also ameliorate sepsis-induced coagulopathy [5,8,9] Another novel pathway may play an important role in attenuating sepsis-induced endothelial dysfunction Heme oxygenase (HO)-1 ... statins might be exerting their beneficial effect Shown in italics are some of the main clinical manifestations pertinent to specific elements of the inflammatory cascade CRP, C-reactive protein;...

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Unit 1: A day in the life of. Listening

Ngày tải lên : 21/06/2013, 01:26

... WHILE-LISTENING Listen and order these pictures WHILE-LISTENING Listen again and decide whether the statements are True (T) or False (F) Mr Lam lives in District Mr Lam usually gets up early After Mr Lam ... District Mr Lam’s first passengers are two pupils Mr Lam has lunch at home with his family After lunch Mr Lam immediately goes back to work T F POST-LISTENING V HOMEWORK - T asks ss to remember the story ... WARM UP Game: JUMBLED WORDS CCLOY  CYCLO RIEDV  DRIVE TALLS DOFO  FOOD STALL NSSEGERPA  PASSENGER PRE-LISTENING WHO IS HE? - He gets up very early - He has got a cyclo - He usually has meals...

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unit1:a day in the life of

Ngày tải lên : 07/07/2013, 01:25

... UNIT A READING B.SPEAKING C.LISTENING D.WRITING •Task1.Choose the opinion A, B, or C that best suits the meaning of the italicised word(s) The alarm goes off at 4:30 A goes wrong B goes away ... rest and has lunch with his family at 11:30.After lunch he always take an hour’s rest At 2:30,they go to the field again and repair the banks of their plot of land After dinner They watch TV and ... realised gained landed 14th July 1995 On that day At first Then A few minutes later One hour later Task Read the passage in the book, page 17, 18 and find all the verbs that are used in the past...

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Unit 1-A day in the life of...

Ngày tải lên : 18/09/2013, 05:10

... and the conclusion of the story Unit 1: A day in the life of Period 4: Writing Task 2.Task 2: Format of a narrative Climax Events Conclusion Unit 1: A day in the life of Period 4: Writing Task ... stared announced took began Unit 1: A day in the life of Period 4: Writing 1.Task 1: Find all the verbs that are used in past simple and the connectors in the story Key: The verbs that are used in ... Read the passage and find all the verbs that are used in past simple and the connectors in the story Simple past Regular verbs land stare announce Irregular verbs take begin S + Ved landed stared...

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Gián án Ụnit 1: A day in the life of...

Ngày tải lên : 02/12/2013, 19:11

... lead in: - It is Linh’sdaily routine -Do you have a daily routine? -is it same or different from Linh? 5ms 2.Pre-task: BRAIN STORM -ask ss think about some their activities in a day in m -after ... and find the winner Arrangeme nt T - whole class KEY: Get up have breakfast clean the floor learning 5.phoning 6.cooking have lunch 8.take a nap 9.sulf the internet 10 watch TV 11 go to the bed ... Stage / timing Prereading 5ms Activities warm-up GUESS THE ACTIVITIES * Instruction: -Divide class in to two teams: team A & team B -Show a video about linh’ daily routine in minute -ask ss...

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Shooting the Sacred Cows of Money Putting a bullet in the head of bad financial advice

Ngày tải lên : 08/02/2014, 18:12

... me my house had appreciated in value Again, that’s capital gains versus cash flow And what people are finding out now that the real estate market has crashed and the value of homes has been sucked ... Michael was that there are three kinds of education There’s academic: reading, writing and arithmetic There’s professional: become a doctor or a lawyer or, in my case, a pilot And there’s financial ... 90% of what we say and Simulating the Real Experience Doing a Dramatic Presentation Active Giving a Talk 70% of what we say Participating in a Discussion Seeing it Done on Location Watching a Demonstration...

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Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx

Ngày tải lên : 19/02/2014, 06:20

... protein, lacking the copper binding domain is capable of domain swapping and forms a dimer as revealed by crystal structure analysis [36] In our case, SEC data collected for samples at pH have ... the mutant The lower intensity may arise from partitioning of the protein into an aggregated state The effect of copper binding on the secondary structure was determined using CD in the far UV ... corresponding to the heat change (lcalÆs)1) with each injection The bottom panel is a plot of heat change on ligand addition (kcalÆmole)1) against the ligand ⁄ steﬁn molar ratio The background heat change...

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Báo cáo Y học: Functional expression of human liver cytosolic b-glucosidase in Pichia pastoris Insights into its role in the metabolism of dietary glucosides ppt

Ngày tải lên : 08/03/2014, 16:20

... between aglycones containing variations in the C-ring, which de®ne the ¯avonoid subclasses In particular, saturation of the C-ring to give a ¯avanone (e.g naringenin, eriodictyol) rather than ¯avone ... b-L-arabinopyranoside These data are in general agreement with those obtained by Daniels et al [9] and con®rm that CBG has a broad speci®city that can accommodate several glycones in the active site, including ... amino acids with a calculated molecular mass of 53.7 kDa A single putative glycosylation site was located at N47 of the deduced amino-acid sequence within the motif KNQT No signal sequence was...

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Philosophy in a New Key A Study in the Symbolism of Reason, Rite, and Art

Ngày tải lên : 14/03/2014, 17:25

... beginning with the early Church Fathers and culminating in the great Scholastics But, at last, its generative ideas—sin and salvation, nature and grace, unity, infinity, and kingdom—had done their ... exploit that valuable insight The acquisition of so decisive a tool must certainly be regarded as one of the great landmarks in human progress, probably the starting point of all genuinely intellectual ... quite elaborate 'ape-ways' into which a newcomer is gradually acculturated, including among other patterns ways of using available instruments for reaching and climbing, a sort of rhythmic play...

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