diversity in function and experience
Báo cáo y học: "Genetic diversity in India and the inference of Eurasian population expansion" doc
... separated into distinct clusters Next, we examined the divergence between Indian and non-Indian populations using pairwise FST estimates In comparing major continental groups, India and Europe have ... history of India has long intrigued anthropologists and human geneticists [3,12-14,20,34,35] A better understanding of Indian genetic diversity and population history can provide new insights into ... Humain collection in Utah, USA, with ancestry from Northern and Western Europe (CEU), Han Chinese in Beijing, China (CHB), Japanese in Tokyo, Japan (JPT), Yoruba in Ibadan, Nigeria (YRI), Chinese...
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Báo cáo y học: "Management of chest pain: exploring the views and experiences of chiropractors and medical practitioners in a focus group interview"
... educational institution offering a training program coordinated by a medical physician However, this is in its infancy and much needs to be worked out This does indicate a growing level of interest in ... ascertain and possibly improve those skills, competencies, and standards for referrals and sharing of clinical information that may improve current and future cross-disciplinary coordination ... chest pain In order for chiropractors to have a role in managing chest pain from the point of entry, they must acquire and demonstrate competence in diagnosing the complaint Chest pain can have...
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Báo cáo y học: "2009 H1N1 Influenza and Experience in Three Critical Care Unit"
... delivery, microbiologic findings, and chest radiologic findings at ICU admission Intubation and mechanical ventilation requirements, adverse events during ICU stay and laboratory findings at ICU admission ... antibiotics included moxifloxacin (in 19 patients), linezolid (in 14 patients), ampicilline-sulbactam (in 13 patients), clarithromycin (in 13 patients), piperacillin-tazobactam (in 12 patients), ... piperacillin-tazobactam (in 12 patients), imipenem (in 11 patients), third generation cephalosporin (in patients), vancomycin (in patients), teicoplanin (in patients), and tigecycline (in patients) Of 61 patients for...
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Criticism and experience - philosophy and literature in the German Enlightenment
... renderings sharpen the understanding and improve the will, transforming a staid treatise on right and wrong, truth and deception, good and evil into popular art And as Breitinger states in full ... leading up to the innovative moves by Meier, Mendelssohn and Philosophy and literature in the German Enlightenment Lessing That prehistory – largely ignored, yet intriguing and innovative in ... process between being and becoming, as the progressive revelation and realisation of the divine in humankind, in individual cultural epochs and stages of national genesis However, since he did not...
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Tài liệu Experiences in Design and Implementation of a High Performance Transport Protocol doc
... Outline • • • • • TCP’s inefficiency in grid applications UDT Design issues Implementations issues Conclusion and future work TCP and AIMD • TCP has been very successful in the Internet ... AIMD (Additive Increase Multiplicative Decrease) • Fair: max-min fairness • Stable: globally asynchronously stable • But, inefficient and not scalable – In grid networks (with high bandwidth-delay ... RTT bias Efficiency of TCP Gb/s link, 200ms RTT, between Tokyo and Chicago 28 minutes On 10 Gb/s link, 200ms RTT, it will take hours 43 minutes to recover from a single loss TCP’s throughput model:...
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Tài liệu Cognitive function and brain structure correlations in healthy elderly East Asians doc
... cognitive function and dementia in the Sacramento Area Latino Study on Aging Am J Clin Nutr 82, 1346–1352 Raz, N., 2005 The aging brain observed in vivo: differential changes and their modifiers In: ... evaluated using the Object and Action Naming Battery (Druks and Masterson, 2000) The tests were administered in either English or Mandarin according to the subject's most proficient language The individual ... 2004) and, in this cohort, it had a large effect on speed of processing and executive function, contributing 30% and 18.5% of the variance in these cognitive domains respectively The elderly in...
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Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx
... mutation in the BTK PH domain; arginine 28 is in dark blue, encircled in red Bottom left: SH2 domain Right: kinase domain The mutated residues are indicated in yellow, a-helices are in cyan, ... protein kinase B (PKB)] In AKT, a cysteine substitution of the corresponding R25 in the pleckstrin homology (PH) domain also results in loss of function [16,17], thereby demonstrating related functions ... proline residues are over-represented, presumably secondary to the strong in uence of prolines on peptide folding [21] Thus, proline is a rigid amino acid creating a fixed kink in a protein chain...
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Tài liệu Báo cáo khoa học: Verprolin function in endocytosis and actin organization Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain doc
... previously showed does contain an actinbinding domain (this actin-binding domain has not yet been mapped) [23] We name the actin-binding domain that we have identified VH2-C and VH2-N because it is ... domain structure Schematic of Vrp1p showing the Vrp1p truncations and mutant proteins used in this study and their various known domains: actin-binding domains, Hof one trap (HOT) domain, and ... only expressing Gal4-AD (AD-vect) Plasmids were introduced into the tester strain PJ69-4A and interaction was assessed by growth on medium lacking histidine and containing mM 3-amino 1,2,4-triazole...
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Tài liệu IMAGINATION, ATTITUDE, AND EXPERIENCE IN AESTHETIC JUDGEMENT pptx
... certain way of looking at things, namely disinterestedly or ‘for their own sake’, by developing the habit or disposition through training so that it comes into play in certain contexts and circumstances, ... role in aesthetic appreciation, by, as it were, lending itself especially to it, rewarding our aesthetic interest and hence inducing the aesthetic attitude or at least facilitating it, and if ... what is involved in appreciating something ‘for its own sake’.8 In so far as the imagination is free, therefore, we can choose to adopt the aesthetic attitude, but the resulting experiences and judgements...
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Tài liệu Báo cáo khoa học: Role of cleavage and shedding in human thyrotropin receptor function and trafficking pdf
... measuring the binding of [125I]Streptavidin Specific binding at each point was normalized with reference to specific binding before the incubation at 37 °C (0-min point) to derive the fraction of initial ... (0–60 min) at 37 °C The concentration of the biotinylated Ig remaining on the cell surface was then quantified by measuring the binding of [125I]Streptavidin In the absence of bTSH, a very weak internalization ... fetal bovine serum was from Biochrom Bovine thyrotropin hormone (bTSH; IUÆmg)1), 3-iso-butyl-1-methylxanthine (IBMX), gelatin, BSA (bovine serum albumin; fraction V) and monensin were obtained from...
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Coral Reef Fishes: Dynamics and Diversity in a Complex Ecosystem ppt
... species diversity and abundance Documenting diversity patterns and examining the factors responsible for producing and maintaining species diversity are major goals in ecology In this respect coral ... Hastings and Springer (1994); b and c, Blum (1989); d, Springer and Williams (1994); e, Blum (1989) and Springer and Williams (1994); f, Winterbottom (1986), Springer (1988) Blum (1989), and Springer ... 36 Wainwrightand Bellwood prominently in this field, including anatomical and mechanical studies of the muscle-skeleton systems involved in feeding (Tchernavin, 1953; Alexander, 1967; Gosline,...
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Báo cáo khoa học: Protein transport in organelles: The composition, function and regulation of the Tic complex in chloroplast protein import pptx
... fast membrane binding and integration into the Tic complex Reducing conditions on the other hand lead to solubilization into the stroma and increased interaction with its other known interaction ... N-terminal half of the protein, including the dehydrogenase domain Specific binding of the FNR is mediated by a unique series of proline/serine-rich repeat motifs located in the C-terminus For the integration ... is in contrast to the function of these motifs in Hop and Hip [40,42,43] Interestingly, binding of Tic40 to Tic110 is favoured when the transit peptide-binding site of Tic110 is occupied by incoming...
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Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx
... Accumulating evidences indicate that HSPGs act to inhibit cellular invasion by promoting tight cell–cell and cell–ECM interactions, and by maintaining the structural integrity and self-assembly of ... heparanase in human cancer by focusing on head and neck carcinoma and multiple myeloma as examples of solid and hematological malignancies Heparanase in head and neck carcinoma: signaling in motion ... seemingly distinct protein domains observed in the 3D model, namely the TIM-barrel and C-domain regions, mediate enzymatic and nonenzymatic functions of heparanase, respectively Interestingly,...
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Báo cáo khoa học: Essential roles of lipoyl domains in the activated function and control of pyruvate dehydrogenase kinases and phosphatase isoform 1 pot
... L2, inner lipoyl domain; B, E1 binding domain; I, oligomer-forming, acetyl-transferase-catalyzing inner domain E3BP domains: L3, N-terminal lipoyl domain; B, E3 binding domain; I, inner domain ... inner domain of E2 Dotted connections indicate binding interactions to the catalytic components (E1 and E3), kinase isoforms (PDK1, PDK2, PDK3, PDK4) and Ca2+-binding of PDP1 in translating and ... protein directly abetting efficient phosphorylation and dephosphorylation, a processing unit Fig E2 and E3BP domains and their binding interactions E2 subunit domains: L1, N-terminal lipoyl domain;...
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Child-friendly health care: the views and experiences of children and young people in Council of Europe member States doc
... important’) • Having treatment explained in advance/being prepared – 44.1% • Being able to understand what the doctor is saying – 49/1% • Being able to ask questions – 44.6% • Being listened to ... cramped and include individual rooms • Have rooms with windows • Have comfortable and clean beds • Have television with lots of channels, DVDs, computer and other games, a games room and internet ... children from the following countries: Armenia, Austria, Bosnia and Herzegovina, Bulgaria, Estonia, Finland, France, Georgia, Germany, Greece, Ireland, Italy, Malta, Netherlands, Poland, Portugal, Romania,...
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The Role of Deployments in Competency Development - Experience from Prince Sultan Air Base and Eskan Village in Saudi Arabia potx
... education and training to inculcate the universal competencies and to track simply whether individuals have (1) experienced different elements of that education and training and (2) participated in ... throughout the survey and in one final open-ended question The actual - survey instrument, including instructions and DAL competency definitions, is provided in the appendix - - Survey Administration ... competency or skill They then indicated the single “best” learning environment for the skill or competency in question Settings included initial training, on-the-job training (OJT)/normal duty assignments,...
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Báo cáo khoa học: LRRK2 in Parkinson’s disease: function in cells and neurodegeneration doc
... but in concert with a number of conserved domains, including a GTPase domain Multidomain proteins that encode functional kinase domains often utilize intrinsic protein kinase activity distinct ... original US government works 6437 Function in cells and neurodegeneration kinase domain encodes a tyrosine kinase-like family member of the larger nonreceptor protein-serine ⁄ threonine kinase ... receptor-associated kinase family Many of these kinases have clear roles in the MAPK pathway, and MLK proteins serve as critical mitogen-activated protein kinase kinase kinase (MAPKKK) proteins in signaling cell...
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Báo cáo khoa học: MicroRNAs – micro in size but macro in function Sunit K. Singh1,2, Manika Pal Bhadra3, Hermann J. Girschick2 and Utpal Bhadra4 pptx
... selection and argonaute (AGO)2 loading [46] Dicer interacts with the dsRNA-binding protein partner, the TAR RNA-binding protein (TRBP), in humans [RDE4 in C elegans and Loquacious (Loqs) in Drosophila], ... process, involving several RNA–protein and protein–protein interactions RISC loading complex (RLC) is an RNA–protein complex that initiates the formation of the RISC The RLC puts a small RNA duplex in ... polyadenylate-binding protein and eIF4E results in stimulation of translational initiation [76] However, some cellular and viral mRNAs initiate translation without the involvement of the m7G cap and eIF4E In...
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INVESTIGATING DIVERSITY IN THE BANKING SECTOR IN EUROPE: THE PERFORMANCE AND ROLE OF SAVINGS BANKS pdf
... in this regard: INVESTIGATING DIVERSITY IN THE BANKING SECTOR IN EUROPE | iii • A larger critical mass of savings banks (and other STV institutions) is likely to enhance competition in the financial ... disappearance of savings banks in countries where the political stance was more in favour of privatising or abolishing INVESTIGATING DIVERSITY IN THE BANKING SECTOR IN EUROPE | this form of banking The overall ... Directive INVESTIGATING DIVERSITY IN THE BANKING SECTOR IN EUROPE | 11 savings banks are public and not all public banks are savings banks For instance, Spanish savings banks are purely private institutions...
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Báo cáo khoa học: Cytoskeleton-modulating effectors of enteropathogenic and enterohemorrhagicEscherichia coli: role of EspL2 in adherence and an alternative pathway for modulating cytoskeleton through Annexin A2 function pot
... is independent of actin pedestal formation, indicating that actin reorganization induced by the Tir–intimin interaction is not necessary for Annexin A2 accumulation Also, accumulation of Annexin ... in the aggregation of actin pedestals and the induction of membrane protrusions (Fig 1) An in vitro assay for the actin bundling activity of Annexin A2 clearly indicated enhancement of Annexin ... been found in all EHEC and EPEC strains examined by hybridization or sequencing [22,23] Furthermore, nucleotide sequences surrounding the espL2 genes of many EHEC and EPEC strains, including EHEC...
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