distending pressures and the stability of lung units

Ensuring Financial Stability: Financial Structure and the Impact of Monetary Policy on Asset Prices

Ngày tải lên : 24/10/2012, 09:40

... zero even at the 95% level in Canada, Finland, the Netherlands, Norway, Sweden, Switzerland, the UK and the US Moreover, while in some countries, (including Finland, the UK and the US) residential ... also for these countries the existence of cointegration could not be rejected We therefore specify the VAR models in the level of the variables Nevertheless, we neither impose the number of cointegrating ... to offset the macro economic effects of the collapse of the bubble).2 Of course, it is by no means clear that central banks are better able to judge the appropriate level of asset prices and the...

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Tài liệu Báo cáo khoa học: Local stability identiﬁcation and the role of a key aromatic amino acid residue in staphylococcal nuclease refolding pdf

Ngày tải lên : 20/02/2014, 01:20

... in the overall (tertiary) structure of the protein Figure shows the fluorescence spectra of wild-type SNase and the four mutants E142O, K133A, W140A and W140O The fluorescence spectra of E142O and ... analysis of protein unfolding The DSC curves of the wild-type protein and the mutants K133A, E142O, W140A and W140O are shown in Fig 3, with their thermodynamic parameters summarized in Table The ... that of the wild-type protein However, the fluorescence in the mutants without tryptophan at 140 (W140A and W140O) was much lower than both the wild-type protein and mutants E142O and K133A Thermal...

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Báo cáo khoa học: Global shape and pH stability of ovorubin, an oligomeric protein from the eggs of Pomacea canaliculata pot

Ngày tải lên : 07/03/2014, 06:20

... structure The high stability of ovorubin oligomers might be due to a shift of the pK of the amino acid residues beyond 12, owing to their involvement in salt bridges At acidic pH, the stability of ovorubin ... giving the best ﬁt to the scattering intensity The resulting dummy atom model represents the shape of the scattering particle To increase the reliability of the results, the ﬁnal model for the dummy ... comparison with the one obtained at pH 6.0 No preferential loss of signal in the region of any of the aromatic residues was observed, suggesting a global loss of the tertiary structure of ovorubin...

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Báo cáo khoa học: Limited mutagenesis increases the stability of human carboxypeptidase U (TAFIa) and demonstrates the importance of CPU stability over proCPU concentration in down-regulating ﬁbrinolysis doc

Ngày tải lên : 07/03/2014, 12:20

... connected to an increased thermostability of the protein itself, we monitored the thermal unfolding of WT and YQ proCPU-CHis Compared with the WT, the midpoint temperature (Tm) of the protein-unfolding ... demonstrated similar Km values of the native and WT, and the YQ mutant CPU with a synthetic and physiological substrate of CPU There seem to be no major changes in the positioning of the propeptide, as indicated ... instructions Expression of mutant proCPUs in insect cells Determination of the half-life (T1/2) of CPU’s activity The T1 ⁄ of the activity of the best mutants secreted in the supernatant of the cells in...

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Báo cáo khoa học: Local stability identiﬁcation and the role of key acidic amino acid residues in staphylococcal nuclease unfolding ppt

Ngày tải lên : 07/03/2014, 21:20

... capacity (DCp) and difference of DCp of mutant from wild-type (%) were determined and the results for the wild-type protein and 20 mutants are given in Table The DHcal and Tm of the wild-type ... calculated based on the description of Privalov and Potekhin [6] residue substitution on the destabilization of secondary structure that leads to the large perturbation of the stability of the protein ... 33% lower than that of the wild-type protein The thermodynamic parameters of the glycine sustitution mutants also differed greatly from the wild-type protein The Tm values of these mutants ranged...

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Báo cáo Y học: Structural and biochemical characterization of calhepatin, an S100-like calcium-binding protein from the liver of lungﬁsh (Lepidosiren paradoxa) docx

Ngày tải lên : 08/03/2014, 22:20

... acetyl group, the molecular mass was calculated to be 8670 Da The alignment of the amino-acid sequence of lung sh calhepatin with other members of the S100 family indicates that the number of amino-acid ... predicted using the SwissModel automated modelling package based on the crystal and/ or NMR structures of other members of the family The molecule is depicted in strand representation, and a helices ... summary of the sequence analyses and the resulting primary structure of lung sh calhepatin is shown in Fig The protein is composed of 75 residues From its aminoacid sequence, assuming that the N-terminus...

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Báo cáo khoa học: Effects of the G376E and G157D mutations on the stability of yeast enolase – a model for human muscle enolase deﬁciency pdf

Ngày tải lên : 16/03/2014, 06:20

... introduced alanine at these two positions, with the aim of determining whether any of the observed effects were a result of changes in the size and charge of the amino acid at these positions Results ... the conformation of this loop Changes in the conformation of the backbone at this point and changes in the orientation of other side chains, as a result of the introduction of the large charged ... at 37 °C, the signiﬁcantly lower yield of the variants may also be the result of dissociation followed by proteolysis of the monomers The effects of these mutations on temperature stability is...

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Báo cáo khoa học: Effects of salt on the kinetics and thermodynamic stability of endonuclease I from Vibrio salmonicida and Vibrio cholerae potx

Ngày tải lên : 16/03/2014, 06:20

... addition, the effects of reciprocal mutations of two non-conserved DNA binding site residues (VsEndA, Q69N and K71N; VcEndA, N69Q and N71K) on the kinetics, thermostability and salt dependence of these ... 4A,D) The results of the present study show that the Km values are strongly affected by the NaCl concentration, similar to the surface charge of the enzyme The higher positive charge of VsEndA therefore ... mutations are not in the immediate vicinity of the active site situated at the bottom of the positively charged pocket, but are still likely to affect the shape, stability and charge of the DNA binding...

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Báo cáo khoa học: Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein Role of the 4¢-phosphopantetheine group in the stability of the holo form of Plasmodium falciparum acyl carrier protein docx

Ngày tải lên : 16/03/2014, 10:20

... in the range 15) 60 C The results of the analysis of these curves using the linear extrapolation model (LEM) are shown in Tables and and Fig 4AC There is a slight temperature dependence of the ... the interaction of the 4Â-PP group with the polypeptide backbone and its effect on the stability of holo-ACP The average major conformation of the holo-ACP NMR structure was analyzed for ligandprotein ... regulated The differences in stability between the two proteins (as indicated by the values of DGwater, Cm and Tg) hence arise from the changes in the surface of the protein because of the interactions...

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Role of an electrolyte and substrate on the stability of porous silicon

Ngày tải lên : 16/03/2014, 15:19

... cmÀ2) Decay of PL intensity is a good indication of the stability of porous silicon particularly of the surface bond conﬁgurations [3,16] In Fig 4(A), decay of the PL intensity at the peak wavelength ... The photochemical etching method with H2O2 solution does not generate a toxic material unlike in the case of HNO3 [11] Moreover, the addition of H2O2 to the etching mixture raises the pH of the ... structure of PS leads to an enormous increase in surface area and the presence of large number of unpaired bonds at the surface which alter the surface recombination rates and consequently the PL...

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Báo cáo khoa học: Analysis of the stability of the spermadhesin PSP-I ⁄ PSP-II heterodimer Effects of Zn 2+ and acidic pH pdf

Ngày tải lên : 23/03/2014, 15:21

... [24], and the C1s protease of the C1 complex of complement [25] Thus, the Trp band can be regarded as a characteristic fingerprint of the native fold of PSP-I and PSP-II The near-UV CD spectra of the ... reversed by the addition of EDTA to the sample (Fig 2A) On the other hand, no significant decrease in the heterodimer stability was observed in the presence of mm CaCl2 (Table 1), emphasizing the specificity ... PSP-I and PSP-II subunits are also characterized by the presence of this band (data not shown), strongly suggesting that they preserve the overall fold of the CUB domain In the presence of Zn2+...

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Báo cáo khoa học: Role of the surface charges D72 and K8 in the function and structural stability of the cytochrome c6 from Nostoc sp. PCC 7119 potx

Ngày tải lên : 30/03/2014, 20:20

... neutralization of the effect of the mutation D72K on the protein’s global charge was not sufﬁcient to fully reverse the negative effect on the stability of cyt c6 The apparent stability of the mutants ... residues K8 and D72 are located near the crossing region of the helices, and the Nx atom of K8 is found ˚ at a distance of 6.2 A from the nearest side-chain oxygen of D72 Taking the functionally and ... electrostatic interactions of the side-chain of D72 that contribute to the stability of cyt c6 are at least partially local, and that the adverse effects of the mutations D72K and D72N cannot be entirely...

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regional business cycle and real estate cycle analysis and the role of federal governments in regional stability

Ngày tải lên : 03/06/2014, 02:10

... (1982), and Cambell and Mankiw (1987) assume the stationarity of the rst log difference of the real GDP and emphasize on the usage of ARIMA models in an attempt to estimate the long-term trend of ... well as the U.S on aggregate exhibited distinct downturn of the real estate cycle between the third quarter of 2006 and the rst quarter of 2007 Finally we found that the state level economic and ... proximity from the economically dominant states plays quite a signi cant role in the formation of the business cycle patterns of the former group of states The business cycle patterns of the major...

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Báo cáo hóa học: " Comment on “on the stability of quadratic double centralizers and quadratic multipliers: a fixed point approach” [Bodaghi et al., j. inequal. appl. 2011, article id 957541 (2011)]" pot

Ngày tải lên : 20/06/2014, 22:20

... stability of the quadratic functional equation Since then, the stability problems of various functional equation have been extensively investigated by a number of authors [8-20] Stability of quadratic ... Park et al Journal of Inequalities and Applications 2011, 2011:104 http://www.journalofinequalitiesandapplications.com/content/2011/1/104 Page of By (2.6), the right-hand side of the above inequality ... (3:8) for all a, b ∈ A and λ ∈ T Letting b = in (3.8), we have T(la) = l2T(a), for all a, b ∈ A and λ ∈ T Now, it follows from the proof of Theorem 2.1 and the continuity f and j that T is ℂ-linear...

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Báo cáo hóa học: " Research Article On the Stability of Quadratic Double Centralizers and Quadratic Multipliers: A Fixed Point Approach" potx

Ngày tải lên : 21/06/2014, 05:20

... “On the stability of the linear functional equation,” Proceedings of the National Academy of Sciences of the United States of America, vol 27, pp 222–224, 1941 Th M Rassias, “On the stability of ... A Baker, The stability of the cosine equation,” Proceedings of the American Mathematical Society, vol 80, no 3, pp 411–416, 1980 15 M Eshaghi Gordji and A Bodaghi, “On the stability of quadratic ... A and λ ∈ T Letting b in 3.14 , we have L λa λ2 L a , for all a, b ∈ A and λ ∈ T Now, it follows from the proof of Theorem 2.1 and continuity of f and φ that T is C-linear If we substitute c and...

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ONE PARAMETER FAMILY OF LINEAR DIFFERENCE EQUATIONS AND THE STABILITY PROBLEM FOR THE NUMERICAL pdf

Ngày tải lên : 23/06/2014, 00:20

... to the number of roots of the characteristic polynomial inside the unit circle and the number of conditions at the end of the interval of integration is equal to the number of roots outside the ... In the discrete case it essentially states that the number of initial conditions should be equal to the number of roots of the characteristic polynomial inside the unit circle and, of course, the ... necessarily to the stability of the zero solution of the same equation It is known that the well-conditioning of a linear boundary value problem, either continuous or discrete, is related to the so called...

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Báo cáo toán học: "The Central Exponent and Asymptotic Stability of Linear Diﬀerential Algebraic Equations of Index 1" pdf

Ngày tải lên : 06/08/2014, 05:20

... can use the restriction of X(t, τ ) to V instead of X in the above formula) Now we will derive some properties of the central exponent of linear DAE of index and of its corresponding ODE Theorem ... C-function of im P (t) of (3.11) Thus, C-classes R of (2.1) and RUimP of the invariant subspace im P of the solution space of (3.11) coincide Suppose that xδ (t) is a solution of the perturbed ... DAE of index and the matrices A(t), B(t), A−1 , P (t) are bounded on R+ Then the central exponent Ωx of (2.1) is smaller than or equal to the central exponent Ωu of the corresponding ODE of (2.1)...

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Báo cáo lâm nghiệp: "Production potential and ecological stability of mixed forest stands in uplands – VI. A beech/larch stand on a mesotrophic site of the Křtiny Training Forest Enterprise" pot

Ngày tải lên : 07/08/2014, 03:22

... related to the frequency of previous measurements Within the analysis of the hypothesis of the dependence of dieback of subdominant trees standard parameters of differences between upper and lower ... the proportion of larch slightly decreased, nevertheless, the species has taken up steadily 35% of the reduced stand area in the last 20 years On the other hand, the proportion of the second main ... At an age of 51 years, the stand with the proportion of beech and larch 80 and 20%, respectively, had the total growing stock of 430 m3/ha With the proportion of beech and larch 60 and 40%, respectively,...

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Báo cáo khoa học: "Impact of different leaf velocities and dose rates on the number of monitor units and the dose-volume-histograms using intensity modulated radiotherapy with sliding-window technique" potx

Ngày tải lên : 09/08/2014, 09:22

... analyse the impact of different DR and LV on the "actual fluence maps" using the same "optimal fluence map" and thereby the impact on the number of monitor units and the dose-volume-histogram of the ... dose areas) The higher the DR and the lower the LV, the higher was the dose given to the PTV and OAR The D55 and D90 of the rectum differed by 0.2% – 3.7% and 0.3% – 3.9% relative to the mean over ... each other by use of the gamma index evaluation with mm and 3% [4-6] The relation between the gamma index and the number of monitor units were analysed The number of monitor units depends on the...

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Báo cáo y học: " Eotaxin and the attraction of eosinophils to the asthmatic lung" ppt

Ngày tải lên : 12/08/2014, 18:20

... strain and species, the challenge and sensitization protocol, and the phase of the response The reasons for this are probably related to contributions by other CCR3 ligands, other chemokine receptors ... cells and Th2 lymphocytes in the lung to generate the cytokines interleukin (IL)-4, IL-13 and tumour necrosis factor (TNF)-α These cytokines stimulate the generation of eotaxin by lung epithelial ... Prevention of the effects of eotaxin is also the aim of therapy developed to interfere with leukocyte trafficking to the lung Neutralization of eotaxin by an antibody is a possible route to therapy...

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