disease medication and teratogenesis
Báo cáo y học: " High blood pressure, antihypertensive medication and lung function in a general adult population"
... antihypertensive medication classes Variable SD Models with mutual exclusive categories No HBP, no medication No HBP, no medication HBP and medication -0.16 0.06 0.02 HBP and medication -0.17 ... treatment - B HBP or medication: high blood pressure or the use of antihypertensive medication - C HBP and medication: high blood pressure and the use of antihypertensive medication; treated but ... 0.04 0.01 HBP and antihypertensive medication as individual variables HBP Medication -0.08 -0.07 0.04 0.04 HBP and antihypertensive medication as individual variables 0.03 0.08 HBP Medication -0.10...
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Pompe disease in children and adults: natural course, disease severity and impact on daily life docx
... 3):671-677 Chapter 79 Disease severity in children and adults with Pompe disease related to age and disease duration Neurology 2005; 64(12):2139-2141 Chapter 87 Course of disability and respiratory ... patients with Pompe disease This ‘Pompe Questionnaire’ was completed for both children and adults and the results were used to study the natural course of the disease and the disease severity in ... enhance the understanding of the variability, progression and natural history of Pompe disease, and in particular of the non-classic or late-onset form, was recognized by Erasmus MC and the International...
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Atopic Dermatitis – Disease Etiology and Clinical Management Edited by Jorge Esparza-Gordillo and Itaru Dekio doc
... associated with the disease might be due to: 1) the disease is polygenic and many different genetic factors may be affected with the diseases, 2) the disease is clinically heterogeneous and different ... squares and circles represent males and females, respectively The closed and open symbols represent affected and non-affected individuals, respectively 30 Atopic Dermatitis – Disease Etiology and ... Atopic Dermatitis – Disease Etiology and Clinical Management Fig Flgft mouse has a truncated and smaller profilaggin and a lack of filaggrin protein 3.2 Flaky tail mouse and ichtyosis vulgaris...
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Centers for Disease Control and Prevention 2013 docx
... and Respiratory Diseases Immunization and Respiratory Diseases - BA Immunization and Respiratory Diseases - PHS Evaluation Transfer Immunization and Respiratory Diseases - PPHF Immunization and ... Infectious Diseases - BA Emerging and Zoonotic Infectious Diseases - PPHF Chronic Disease Prevention and Health Promotion Chronic Disease Prevention and Health Promotion - BA Chronic Disease Prevention ... and promoting quality of life by preventing and controlling disease, injury, and disability, as well as reducing the health and economic burden of the leading causes of disease, disability, and...
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KDIGO Clinical Practice Guideline for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) pdf
... biochemical and hormonal values in the diagnosis of CKD–MBD requires an understanding of assay type and precision, interassay variability, blood sample handling, and normal postprandial, diurnal, and ... and hormonal values requires an understanding of assay type and precision, interassay variability, blood sample handling, and normal postprandial, diurnal, and seasonal variations in individual ... biopsy and DXA, and other bone imaging tests, including plain radiographs, qCT, and quantitative US predict (a) clinical outcomes and (b) surrogate outcomes for bone and CVD? How imaging tests and...
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Coeliac disease - Recognition and assessment of coeliac disease pdf
... delayed puberty and dental complications 2.4 Signs and symptoms of coeliac disease and coexisting conditions with coeliac disease 2.4.1 Evidence review – signs and symptoms Recognition and assessment ... guideline 86 Coeliac disease Disclaimer NICE clinical guidelines are recommendations about the treatment and care of people with specific diseases and conditions in the NHS in England and Wales This ... diet), and presents in both children and adults Because of the disparate nature of its signs and symptoms, and the historical belief that it is not a common disease, there is concern that coeliac disease...
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Fatty Liver Disease: NASH and Related Disorders ppt
... STEATOSIS, NASH AND RELATED CONDITIONS diseases, drugs and toxins (especially Wilson’s disease) , including alcohol in older children and adolescents, malnutrition, short gut syndrome and cystic fibrosis, ... obesity and type diabetes (see Chapter 19) [46,47] Some possible reasons for high rates of obesity and type diabetes in contemporary affluent societies (‘east’ and ‘west’, ‘north’ and ‘south’), and ... NAFLD and NASH have increased from previous estimates, and are now in the range 17–33% for NAFLD and 5.7–17% for NASH This increase and high prevalence is related to societal changes in obesity and...
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Báo cáo khoa học: LRRK2 in Parkinson’s disease: genetic and clinical studies from patients ppt
... individuals (eight unaffected and eight affected) in family A were genotyped and all affected were heterozygous for the mutation and all the unaffected aged over 60 years Table Genes and loci linked with ... may explain between 5% and 13% of familial and 1–5% of Genetic and clinical studies of LRRK2 sporadic PD [4–9] (Fig 1) The variability depends on the ethnic population and the extent of genetic ... South Africa and in some European countries, such as Poland, Greece and Germany However, that appears as a predilection for some ethnic races This mutation accounts for 13.3% of sporadic and 29.7%...
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A REPORT COMMISSIONED BY THE CENTERS FOR DISEASE CONTROL AND PREVENTION pot
... humans These disease results from the interaction between genetic advances allow an expanded approach to susceptibility factors and the environment, broadly understanding how multiple genes and gene ... research, and innovative approaches to disease prevention and management are possible throughout the pathway by which basic research findings are developed into potential methods to prevent disease and ... research or intervention methods, goals, and uses of data – and attempting to understand the needs and culture of communities by working with community leaders and/ or trusted “community agents” When...
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Báo cáo khoa học: Active-site-specific chaperone therapy for Fabry disease Yin and Yang of enzyme inhibitors pptx
... identified for Gaucher disease [20,21], Tay-Sachs and Sandhoff disease [22] (details for Gaucher and Tay-Sachs ⁄ Sandhoff diseases are reviewed separately), GM1-gangliosidosis [23], and retinitis pigmentosa ... contains antiparallel b strands The galactose ligand is shown in yellow and red (B) Fabry disease- causing point mutations are shown on the human a-Gal A dimer The red, blue, and green bonds show mutations ... N215S, Q279E, M296I, and M296V), four mutations found in classic patients (E59K, A156V, L166V, and R356W), and two mutations present in both variant and classic patients (A97V and R301Q) were efficiently...
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EUROPEAN CENTRE FOR DISEASE PREVENTION AND CONTROL ppt
... disease out breaks and epidemics and setting priorities • A communication and response system, which provides timely and regular feedback to Member States and EU Institutions and citizens and ... operational and it was linked to the EU Early Warning and Response System (EWRS) Communicable diseases don’t respect national borders or sector and agency demarcations, and for this reason prevention and ... Centers for Disease Control and Prevention (CDC) in Atlanta, USA for example, and with similar stakeholders in Asia, India and Thailand The ECDC has been put on the map of the world, and it clearly...
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alzheimers disease, methods and protocols
... disease Nature 97, 192–193 Allsop, D., Landon, M., and Kidd, M (1983) The isolation and amino acid composition of senile plaque core amyloid Brain Res 259, 348–352 Selkoe , D J., Ihara, Y., and ... History of dementia and Parkinson’s disease in first degree relatives of patients with Alzheimer’s disease Neurology 39, 1589–1592 Hoininen, H and Heinonen, O P (1982) Clinical and etiological aspests ... presenilin-1 gene and late-onset Alzheimer’s disease Lancet 347, 509–512 93 Kehoe, P., Williams, J., Lovestone, S., Wilcock, G., and Owen, M J (1996) Presenilin polymorphism and Alzheimer’s disease Lancet...
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celiac disease, methods and protocols
... Epidemiology of Coeliac Disease, Auricchio, S and Visakorpi, J M., eds., Karger, Basel, Switzerland, pp 142–150 Young, W F and Pringle, E M (1971) 110 children with coeliac disease, 1950– 1969 Arch ... sprue’) Gastroenterology 102, 330–354 Celiac Disease 12 Shewry, P R., Tatham, A S., and Kasarda, D D (1992) Cereal proteins and coeliac disease, in Coeliac Disease, Marsh, M N., ed., Blackwell Scientific, ... S., and Marsh, M N (1997) Linkage analysis of candidate regions for coeliac disease genes Hum Mol Genetics 6, 1335–1339 15 Nilsen, E M., Lundin, K., Krajci, P., Scott, H., Sollid, L., and Brandtzaeg,...
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parkinsons disease, methods and protocols
... forward and reverse primers and selects the best pair based on preselected criteria Forward primers duplicate DNA from the 5' to the 3' end of the strand, and reverse primers duplicate the strand ... Parkinson’s disease J Neuropathol Exp Neurol 55, 259–272 Duffy, P E and Tennyson, V M (1965) Phase and electron microscopic observations on Lewy bodies and melanin granules in the substantia nigra and ... EDTA (Sigma), and 995 mL ddH2O Stir until completely dissolved and store at room temperature When ready to use, make 1X dilution with ddH2O Agarose (Sigma) Parkinson’s Disease and α-Synuclein...
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meningococcal disease, methods and protocols
... of cases of meningococcal disease, and from their contacts (3), a finding of immense significance in advancing understanding of the epidemiology and pathogenesis of the disease Early serological ... requested, and diagnostic questions can be crucial in directing the optimal handling and reporting of the specimen in the laboratory For throat and nasopharyngeal cultures, it is mandatory to ... Close caps and vortex the tubes thoroughly and incubate at room temperature for 10 Pipette 500 µL of ethanol into each of the samples and control tubes Close caps and mix each tube and leave at...
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renal disease, techniques and protocols
... B and Raskin, P (1988) Nephropathy and hypertension in diabetes Med Clin N Am 82, 877–907 Sowers, J R and Epstein, M (1995) Diabetes mellitus and associated hypertension, vascular disease and ... J., and Mucher, G (1998) Autosomal recessive polycystic kidney disease J Mol Med 76, 303–309 McDonald, R A and Avner, E D (1996) Mouse models of polycystic kidney disease, in Polycystic Kidney Disease ... humankind today, such as cancer and cardiovascular disease Perhaps a more appropriate metaphor for the pathophysiology of diseases such as cancer and cardiovascular disease is a “web of causality”—an...
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Báo cáo hóa học: "Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-a 2b treatment" pptx
... factor-b (TGF-b), IL-10, and autoantibody levels were also measured, along with efficacy and safety Patients and methods Patients Patients with stage III and IV operable and inoperable melanoma ... of study materials or patients MN, GG, and MCa collected and assembled data for the Treg assay RC and GC were responsible for the TGFb and IL-10 assays MCe and GB were involved with the autoantibody ... coronary syndrome, and myocardial infarction); uncontrolled diabetes mellitus; thyroid function disorders; a history of psychiatric illness and depression; and a history of autoimmune disease Control...
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báo cáo hóa học: " Comparing a disease-specific and a generic health-related quality of life instrument in subjects with asthma from the general population" pot
... systemic hypertension (22% and 26%), cardio-vascular diseases (8% and 12%), diabetes (5% and 9%) and cancer (5% and 3%) in subjects who answered the quality of life questionnaires and subjects who refused ... the AQLQ domain scores were found between and 2, and and 7, respectively, and when the SF-36 domain scores were found between and 10, and 90 and 100, respectively For internal consistency reliability, ... between 25% and 75% of the forced vital capacity *p = 0.01 and p < 0.05 compared to groups A and B, respectively; †p = 0.01 and p < 0.05 compared to groups A and B, respectively; ‡p < 0.01 and p
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báo cáo hóa học: " Chronic obstructive pulmonary disease (COPD) and occupational exposures" pptx
... data on symptoms and diseases, others have presented data on lung function, and a few have done both Although a certain degree of standardization has been accomplished for cough and phlegm, dyspnea ... the burden of airway disease include standard setting for exposure in and out of the workplace, attribution criteria for compensation, health care costs and their assignment, and health care resources ... strategy for the prevention and management of and research in chronic obstructive pulmonary disease National Heart, Lung, and Blood Institute Workshop Summary Bethesda, Maryland, August 29–31, 1995...
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báo cáo hóa học:" Osteoarthritis: quality of life, comorbidities, medication and health service utilization assessed in a large sample of primary care patients" potx
... vessel disease (CVD), elevated cholesterol level (low density lipoprotein (LDL) > 200 mg/dl), ulcer or stomach disease, asthma/chronic obstructive pulmonary disease (COPD), kidney disease, cancer and ... questionnaires Patients were asked to mention all disease specific medications they take additionally to prescriptions, including OTC medication, homeopathic medication and symptomatic slow-acting drugs in ... on medication (e.g OTC medication) , HSU (e.g visits to healers) and treatments (e.g acupuncture) were available Page of (page number not for citation purposes) Journal of Orthopaedic Surgery and...
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