diagnosis prognosis and personalised therapy

Báo cáo khoa học: "Recently published papers: Tracheostomy: why rather than when? Obesity: does it matter? And stroke: diagnosis, thrombosis and prognosis" ppt

Ngày tải lên : 13/08/2014, 03:20

... for midazolam and 34.2% versus 15.4% for propofol There were no differences in prescribed sedatives in the two days before and after tracheostomy Stroke: diagnosis, thrombosis and prognosis The ... morbidity and mortality, is increasing internationally In New York, Drs Solh and Jaafar [7] looked at 455 critically ill patients who underwent a surgical trachesotomy and compared the incidence and ... an MRI and subsequent thrombolysis where appropriate and continuation of care should be in stroke units and, although this represents ‘best’ treatment, is this the best use of resources and efforts?...

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Báo cáo y học: "Comparison between single antiplatelet therapy and combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with antiphospholipid syndrome"

Ngày tải lên : 26/10/2012, 09:48

... Med Sci 2010, with APS We therefore compared single antiplatelet therapy and a combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with ... with venous and arterial occlusive disease in multiple organs, miscarriages, and livedo reticularis Materials and Methods We focused on the secondary prevention of stroke with APS, and compared ... prevention of stroke with APS, and compared single antiplatelet therapy and a combination of antiplatelet and anticoagulation therapy in ischemic stroke patients with APS The subjects were 20...

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Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in human malignancies and potential therapy pdf

Ngày tải lên : 16/02/2014, 14:20

... phosphatidylinositol 3-kinase and Hedgehog, and thus affects metabolism, the cell cycle, gene expression, developmental processes and oncogenesis Active GSK3 is indicative of absent WNT-signaling and leads to ... leukemia patients and collected a total of 64 different MLL fusion partners The analyzed MLL fusion alleles were classified according to their occurrence in ALL and AML patients and their putative ... localization and their putative function Twenty-five of them represent nuclear proteins and 33 represent cytosolic proteins; one fusion partner could not be classified With few exceptions (e.g the AF4 and...

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Tài liệu IMPLANT AND REGENERATIVE THERAPY IN DENTISTRY A GUIDE TO DECISION MAKING docx

Ngày tải lên : 16/02/2014, 21:20

... osteotome therapy and restoration with a stock abutment and crown Implant placement with concomitant sinus augmentation therapy and restoration with a stock abutment and crown Sinus augmentation therapy ... regenerative therapy, or the necessity of performing regenerative therapy and placing the implant at a second surgical visit These considerations signiﬁcantly impact the time and cost of therapy and the ... followed by endodontic therapy and post and BLBS033-Fugazzotto March 13, 2009 18:56 Tooth Retention and Implant Placement (a) (c) (e) 17 (b) (d) (f) Figure 1.14 (a–f) Buccal and clinical views of...

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Tài liệu Alcohol-use disorders: diagnosis, assessment and management of harmful drinking and alcohol dependence docx

Ngày tải lên : 21/02/2014, 11:20

... disorders: diagnosis, assessment and management of harmful drinking and alcohol dependence NICE clinical guideline 115 peer relationships and social and family functioning developmental and cognitive ... activity and domestic violence, and an increased rate of significant mental and physical disorders Although alcohol dependence is defined in ICD-10 and DSM-IV in categorical terms for diagnostic and ... dependence affects 4% of people aged between 16 and 65 in England (6% of men and 2% of women), and over 24% of the English population (33% of men and 16% of women) consume alcohol in a way that...

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Tài liệu GLOBAL STRATEGY FOR THE DIAGNOSIS, MANAGEMENT, AND PREVENTION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE pptx

Ngày tải lên : 21/02/2014, 12:20

... of a diagnosis of COPD Spirometry is needed to establish a diagnosis of COPD For the diagnosis and assessment of COPD, spirometry is the gold standard as it is the most reproducible, standardized, ... wood and other biomass fuels has also LER IA INTRODUCTION MA T COPD is a leading cause of morbidity and mortality worldwide and results in an economic and social burden that is both substantial and ... prevalence and mortality were greater among men than 18 RISK FACTORS Infections (viral and bacterial) may contribute to the pathogenesis and progression of COPD49, and the bacterial , and 51 A...

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Tài liệu The Diagnosis, Evaluation, and Management of von Willebrand Disease ppt

Ngày tải lên : 21/02/2014, 12:20

... lived on the Åland Islands and was brought to Deaconess Hospital in Helsinki, Finland, in 1924 to be seen by Dr Erik von Willebrand.10 He ultimately assessed 66 members of her family and reported ... to the diagnosis and management of VWD and could have significant implications for medical practice and for public health Aside from needs for better information about VWD prevalence and the ... Willebrand Syndrome 17 Prothrombotic Clinical Issues and VWF in Persons Who Do Not Have VWD 18 Diagnosis and Evaluation 19 Introduction 19 Evaluation of the Patient 19 History, Signs, and Symptoms...

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Diagnosis, Management, and Treatment of Hepatitis C: An Update docx

Ngày tải lên : 08/03/2014, 14:20

... Semi-automated RT-PCR Semi-automated TMA Manual TMA 50 50 Ͻ50 10 Ͻ50 Diagnosis and monitoring Diagnosis and monitoring Blood screening Diagnosis and monitoring Blood screening Abbreviations: RT-PCR, reverse ... or ascites), and ● Acceptable hematological and biochemical indices (Hemoglobin 13 g/dL for men and 12 g/dL for women; neutrophil count 1500 /mm3 and serum creatinine Ͻ1.5 mg/dL, and ● Willing ... patients who received the standard ribavirin dose and in 38% of those treated with the low dose.327 Serious adverse events developed in 14% and 18% of recipients of the standard and low ribavirin doses,...

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Osteoarthritis – Diagnosis, Treatment and Surgery Edited by Qian Chen pptx

Ngày tải lên : 17/03/2014, 02:20

... Boughton and Hugh Mackenzie Chapter 11 Low Level Laser Therapy in the Treatment of Temporomandibular Joint Arthritis: Questions and Answers Marini Ida and Gatto Maria Rosaria Part 211 Diagnosis ... Developed and Developing Countries: Gender and Age Long-Term Treatment of Osteoarthritis Pain: Achieving a Balance Between Efficacy and Tolerability for a Successful Chronic Therapy 25 Differences and ... from approximately 7% in patients between 40 and 44 years of age to 26% in patients between 60 and 64 years of age and to 49% in patients between 80 and 84 years of age (Kopec et al., 2007) The...

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LIVER TUMORS EPIDEMIOLOGY, DIAGNOSIS, PREVENTION AND TREATMENT potx

Ngày tải lên : 23/03/2014, 17:20

... assessment of therapy efficiency (chemotherapy and chemoembo contrast-enhanced CT [45] b assessment of therapy efficiency (chemotherapy and chemoem‐ disappearance of the circulatory bed and suggests ... differential diagnosis with hypervascular metastases or HCC is difficult and thus a correlation with other imaging techniques is mandatory [27] 20 Liver Tumors - Epidemiology, Diagnosis, Prevention and ... epidemiology and risk factors for pri‐ mary liver cancer, the role of contrast enhanced ultrasound is reviewed, as are the very important roles of anti-viral therapy and the exciting potential of immunotherapy...

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Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy pot

Ngày tải lên : 28/03/2014, 14:20

... guidelines7 and those from the ISSHP,66 with the exception of the gestational age criterion (see Prediction, Prevention, and Prognosis of Preeclampsia and Place of Care, and specific therapy) Although ... manifestations of preeclampsia: hypertension and proteinuria Accordingly, the measurement of blood pressure and proteinuria and the diagnosis of hypertension and clinically significant proteinuria ... immune CHAPTER 1: Diagnosis and Classification Table Investigations to diagnose or monitor maternal and fetal well-being in preeclampsia Investigations for prognosis Investigations for diagnosis Description...

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ethical issues in molecular medicine and gene therapy

Ngày tải lên : 10/04/2014, 22:10

... the case of gene therapy as well Appropriate Candidates for Gene Therapy We now turn to another dimension of ethics issues in gene therapy, namely, who the candidates are for therapy We distinguish ... true in the case of Donald and the gene therapy clinical trial we are considering for his CF? 326 ETHICAL ISSUES IN MOLECULAR MEDICINE AND GENE THERAPY In the case of gene therapy there appear to ... care can make the difference between life and death or 328 ETHICAL ISSUES IN MOLECULAR MEDICINE AND GENE THERAPY the difference between permanent injury and the healing of that injury/restoration...

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molecular medicine and gene therapy. an introduction

Ngày tải lên : 10/04/2014, 22:10

... genes is up-regulated and of other genes down-regulated (Adapted from Anderson and Anderson, Electrophoresis, 1996.) MOLECULAR MEDICINE AND GENE THERAPY: AN INTRODUCTION gene and the down-regulation ... fuller understanding of biological clocks and the aging process 22 MOLECULAR MEDICINE AND GENE THERAPY: AN INTRODUCTION SUGGESTED READINGS Gene Therapy Anderson WF Human gene therapy Science ... 2 MOLECULAR MEDICINE AND GENE THERAPY: AN INTRODUCTION and ethical considerations, such as the cloning of sheep and primates Others lead to a profound understanding of the pathogenesis...

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components of cell and gene therapy

Ngày tải lên : 10/04/2014, 22:11

... neurodegeneration and provide a way to test gene therapy strategies for CNS disorders, injury, or aging 210 COMPONENTS OF CELL AND GENE THERAPY FOR NEUROLOGICAL DISORDERS NEUROTROPHIC FACTORS AND GENE THERAPY ... experience numbness and muscle weakness in the limbs and difﬁculty with coordination and balance These symptoms can be severe enough to impair walking and standing Speech difﬁculty, fatigue, and dizziness ... Neurological Disorders and Brain Tumors Humana, Totowa, NJ, 1998 Doering LC Gene therapy and neurodegeneration Clin Neurosci 3:259–321, 1996 Kaplitt MG, Loewy AD Viral Vectors, Gene Therapy and Neuroscience...

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Báo cáo hóa học: " Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer" ppt

Ngày tải lên : 18/06/2014, 16:20

... and ovarian cancer [2] Standard treatment for advanced EOC involves surgical debulking followed by adjuvant chemotherapy with a combination of a platinum compound (cisplatin or carboplatin) and ... surgery was not available Standard adjuvant therapy was platinumbased chemotherapy, from the 1990s given in combination with paclitaxel whereby = negative, = intermediate and = moderate-strong intensity ... of good prognosis in EOC and a predictor of response to platinum-based chemotherapy, most likely a combination of both, particularly in the light of the previously demonstrated good prognosis...

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Báo cáo sinh học: "The iSBTc/SITC primer on tumor immunology and biological therapy of cancer: a summary of the 2010 program" doc

Ngày tải lên : 18/06/2014, 19:20

... Biological Therapy of Cancer, iSBTc), aims to improve cancer patient outcomes by advancing the science, development and application of biological therapy and immunotherapy The society and its educational ... (105 , 106 and 107 DC per injection) and two different delivery routes (intravenous and intradermal) Immune assessment was performed prior to treatment and at days 14, 28, 35, 56, and 112 Immune ... specific immune cell subsets and tumor antigens, co-stimulation, negative regulation and tumor cell biology As we improve our understanding of tumor immunology and combine and test various strategies,...

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Báo cáo hóa học: " Septic AKI in ICU patients. diagnosis, pathophysiology, and treatment type, dosing, and timing: a comprehensive review of recent and future developments" doc

Ngày tải lên : 21/06/2014, 01:20

... conceived and wrote the review WB, JDR, EDW, and VC participated in literature search and selected appropriate articles PMH and HDS participated in design, coordination, and writing All authors read and ... and SLED the same level of evidence [49], although there are only very few randomized studies comparing SLED and CRRT, whereas there are large numbers of randomized studies that compare IHD and ... histopathological substrate of septic AKI and, above all, it is not proven that urine tests can discriminate between functional and structural AKI Diagnosis of AKI and potential role of biomarkers Early...

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Atherothrombosis — Wave Goodbye to Combined Anticoagulation and Antiplatelet Therapy? ppt

Ngày tải lên : 27/06/2014, 00:20

... to prevent bleeding and to devise safer antiplatelet and anticoagulant drugs Dr Mohler reports receiving lecture fees from Bristol-Myers Squibb, Sanofi, and Astra-Zeneca and grant support from ... coagulation and prothrombin time of the blood: a clinical study JAMA 1942;120:1009-15 11 The Warfarin Antiplatelet Vascular Evaluation Trial Investigators Oral anticoagulant and antiplatelet therapy and ... Disease: Safety and Efficacy and (PRECISE and PRECISE 2),4,5 are reported in this issue of the Journal The two double-blind, placebo-controlled trials have many features in common and one unique296...

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Addition of Clopidogrel to Aspirin and Fibrinolytic Therapy for Myocardial Infarction with ST-Segment Elevation pdf

Ngày tải lên : 27/06/2014, 00:20

... fibrinolytic therapy or combination reduced fibrinolytic therapy and platelet glycoprotein IIb/IIIa inhibition: the GUSTO V randomised trial Lancet 2001;357:1905-14 24 Assessment of the Safety and Efficacy ... than 75 years of age, and those with a history of coronary-artery bypass grafting The efficacy and safety of adding treatment with clopidogrel to aspirin and fibrinolytic therapy in these groups ... with ST-segment elevation and who receive fibrinolytic therapy, aspirin, and (when appropriate) weight-based heparin, clopidogrel offers an effective, simple, inexpensive, and safe means by which...

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