dhea and glucose metabolism in skeletal muscle
Báo cáo khoa học: Progressive decrease of phosphocreatine, creatine and creatine kinase in skeletal muscle upon transformation to sarcoma pot
... with MCK in striated skeletal and heart muscles and ubiquitous uMitCK is present in smooth muscle, brain, neuronal and other non -muscle Table Creatine and phosphocreatine content in normal muscle ... levels Levels of creatine and creatine kinase in sarcoma of creatine and an increased choline ⁄ creatine ratio, and a decrease in the activity of CK and some of its isoforms in several different ... was developed in the hind leg of mice by injecting 3MC, a chemical carcinogen, or by injecting into the hind leg existing sarcoma 180 cells, which had been previously maintained in the peritoneal...
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Báo cáo khoa học: A new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-jB pathway in skeletal muscle pdf
... heart and skeletal muscle [18,22,23], Ankrd2 is mainly expressed in skeletal muscle [18,24,25], CARP in the heart [18,21,26–28] and DARP in equivalent amounts in both tissues [20] Interestingly, ... calpain was investigated A direct, in vitro digestion of CARP by calpain using recombinant proteins could not be attempted because calpain is inactivated during purification [45] In skeletal muscle ... control, an interaction test of calpain and N2A-titin is performed (upper left panel) The yeasts carrying calpain and CARP grow on the selective medium, indicating that CARP and calpain interact...
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báo cáo hóa học: " Influence of dietary state and insulin on myocardial, skeletal muscle and brain [18F]fluorodeoxyglucose kinetics in mice" pptx
... other hand, myocardial glucose metabolism in response to insulin clamping is not always parallel to that in skeletal muscle and/ or whole-body glucose metabolism For instance, myocardial glucose metabolism ... humans (12.4 and 4.3 mg/min/100 g after glucose loading and fasting, respectively) [21] Reduced heart and skeletal muscle glucose or FDG metabolism under insulin clamping conditions in patients ... [18F]-fluorodeoxyglucose (FDG) kinetics in mice in a non-fasting condition or a fasting condition differ after injection of insulin and furthermore assess the effect on FDG kinetics in the muscle and brain...
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DISTINCTIVE CHARACTERISTICS OF INSULIN GLUCOSE METABOLISM IN INTRAUTERINE GROWTH RESTRICTED AND IMPAIRED GLUCOSE TOLERANCE NONHUMAN PRIMATES
... protein serine/threonine kinase protein serine/threonine kinase transmembrane receptor protein tyrosine kinase adaptor 3-phosphoinositidedependent protein serine/threonine kinase phosphorylation and ... Fasting hyperglycemia and glucose (30% ) intolerance observed in IUGR Table 1: Summary of studies using IUGR rodent model and exhibit changes in organs and gene involving in insulin -glucose metabolism ... SLC2A4RG, and fold decrease in MSTN, indicating elevated insulin -glucose signaling All these conclude that the insulin glucose metabolism in IUGR subjects were accelerated at the beginning and thus...
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DISTINCTIVE CHARACTERISTICS OF INSULIN GLUCOSE METABOLISM IN INTRAUTERINE GROWTH RESTRICTED AND IMPAIRED GLUCOSE TOLERANCE NONHUMAN PRIMATES
... protein serine/threonine kinase protein serine/threonine kinase transmembrane receptor protein tyrosine kinase adaptor 3-phosphoinositidedependent protein serine/threonine kinase phosphorylation and ... Fasting hyperglycemia and glucose (30% ) intolerance observed in IUGR Table 1: Summary of studies using IUGR rodent model and exhibit changes in organs and gene involving in insulin -glucose metabolism ... SLC2A4RG, and fold decrease in MSTN, indicating elevated insulin -glucose signaling All these conclude that the insulin glucose metabolism in IUGR subjects were accelerated at the beginning and thus...
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DISTINCTIVE CHARACTERISTICS OF INSULIN GLUCOSE METABOLISM IN INTRAUTERINE GROWTH RESTRICTED AND IMPAIRED GLUCOSE TOLERANCE NONHUMAN PRIMATES
... protein serine/threonine kinase protein serine/threonine kinase transmembrane receptor protein tyrosine kinase adaptor 3-phosphoinositidedependent protein serine/threonine kinase phosphorylation and ... Fasting hyperglycemia and glucose (30% ) intolerance observed in IUGR Table 1: Summary of studies using IUGR rodent model and exhibit changes in organs and gene involving in insulin -glucose metabolism ... SLC2A4RG, and fold decrease in MSTN, indicating elevated insulin -glucose signaling All these conclude that the insulin glucose metabolism in IUGR subjects were accelerated at the beginning and thus...
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Tài liệu Báo cáo khoa học: On the mechanism of action of the antifungal agent propionate Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans doc
... containing glucose and propionate, the growth rate of both strains increased and the effect of propionate became less apparent Finally, in media containing acetate and propionate but no glucose, ... NADPÆmin)1Æmg protein)1 Determination of maintenance In order to calculate the amount of glucose used for maintenance, the wild-type strain A26 was used Four 100-mL aliquots of glucose minimal ... containing 50 mM glucose as sole carbon source and 50 mM glucose + 100 mM acetate, all strains were incubated for 20 h; on 50 mM glucose + 100 mM acetate + 100 mM propionate, all strains were incubated...
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Tài liệu Báo cáo khoa học: Regulation of connective tissue growth factor (CTGF/CCN2) gene transcription and mRNA stability in smooth muscle cells Involvement of RhoA GTPase and p38 MAP kinase and sensitivity to actin dynamics docx
... data are in line with previous observations indicating that physiological activators of the p38 and PtdIns 3-kinase pathways including thrombin, dexamethasone, angiotensin II and prostaglandins stimulate ... for 30 and then fixed, permeabilized and stained for F-actin with rhodamine-conjugated phalloidin The effects of toxin B and latrunculin B on the actin filaments was examined by preincubating the ... barbed-end actin and determine the level and distribution of F-actin [34] Therefore, it is tempting to speculate that interactions between monomeric G-actin and actin-binding proteins are a potential...
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Báo cáo khoa học: Enzymes of creatine biosynthesis, arginine and methionine metabolism in normal and malignant cells Soumen Bera1, Theo Wallimann2, Subhankar Ray1 and Manju Ray1 potx
... estimation of proline and ornithine J Biol Chem 199, 91–95 45 Van Pilsum JF, Martin RP, Kito E & Hess J (1956) Determination of creatine, creatinine, arginine, guanidinoacetic acid, guanidine, and methyl-guanidine ... observations indicated that ornithine content and ODC expression were high in tumors This indicates that the pathway of polyamine formation from arginine metabolism is favored in this tissue Again, arginase ... and 5.5 mm glucose) and suspended in a fresh incubation buffer, but this time without creatine Creatine content within the cells was monitored at indicated time points to ascertain the creatine...
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Báo cáo khoa học: Enzymatic features of the glucose metabolism in tumor cells ppt
... in metabolism A Herling et al synthase kinase 3b, a multifunctional serine ⁄ threonine kinase that functions in diverse cellular processes including proliferation, differentiation, motility and ... finding of two potential binding sites for HIF-1 in the first intron of the PK-M gene On the other hand, Yamada and Noguchi [116] reported that there is no HIF-1 binding sequence 5¢-ACGTGC-3¢ in ... normally only expressed in intestinal and renal epithelial cells and endothelial cells at the blood–brain barrier Metabolic control analysis of glycolysis in AS-30D carcinoma and HeLa cells provided...
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Báo cáo khoa học: Unchanged thymidine triphosphate pools and thymidine metabolism in two lines of thymidine kinase 2-mutated fibroblasts docx
... involvement of TK2 in the in situ phosphorylation of thymidine, Ca and Pa lines were also incubated in the presence of lM BVDU added 15 before [3H]thymidine, and the incubation was continued for (dotted ... confirming the involvement of TK2 in the phosphorylation of thymidine in both cell lines inferred above (Table 1) 1108 from the inhibition of thymidine phosphorylation in vitro caused by KIN109 ... c.p.m.Æpmol)1 in Ca and Pb cells, and about 5000 in Cb and Pa cells (Fig 2B), indicating that one-third of the dTTP of Ca and Pb cells and between one-quarter and one-fifth of the dTTP of Cb and Pa cells...
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báo cáo hóa học: " Post-traumatic hypoxia exacerbates neurological deficit, neuroinflammation and cerebral metabolism in rats with diffuse traumatic brain injury" pptx
... (hours) E * D Brain IL-2 (pg/mg protein) Brain TNF (pg/mg protein) B Time Post-Injury (hours) C Brain IL-4 (pg/mg protein) * Brain IL-1 (pg/mg protein) Brain IL-6 (pg/mg protein) A Page of 16 ... described above and killed at or days after injury (n = per group per timepoint) Brains were perfusion fixed using 4% paraformaldehyde and embedded in paraffin wax Brain tissue blocks were cut into 10 ... rats being 2.43 ± 0.54% in TAI and 2.04 ± 0.45% in TAI+Hx animals The production of cytokines is enhanced following TAI +Hx The neuroinflammatory response was determined by measuring changes in cytokine...
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Báo cáo lâm nghiệp: "Oak growth, development and carbon metabolism in response to water stress" pps
... decrease, indicating that Q macrocarpa could not utilize rain water in the upper soil layers and Knapp, 1986) The ability to increase root growth into and to increase root proliferation within enriched ... conflicting problem of maintaining some degree of photosynthesis while minimizing water loss Stomatal control in response to varying moisture stress is the first and perhaps the most important step in ... seedlings or of decreases in carbon fixation or shifts in carbon pools, starch hydrolysis and efficiency of sucrose loading into the phloem may increase to maintain transport are young developing...
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Báo cáo khoa học: "Differences of genetic variation based isozymes of primary and secondary metabolism in Quercus petraea" ppt
... the remaining in secondary metabolism (respectively, groupsI and II) (Bergmann, 1991) Allelic frequencies were estimated within each population; observed and expected heterozygosities within populations ... studied Enzymes involved in secondary metabolism exhibited higher withinpopulation variation than enzymes involved in primary metabolism These discrepancies were due to differences in allelic frequency ... diversity in plant species In: Plant Population Genetics, Breeding and Genetic Resources (Brown AH, Clegg MT, Kahler AL, Weir BS, eds) Sinauer Associates, Sunderland, MA, 23-42 Kleinschmit J (1993) Intraspecific...
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Báo cáo y học: "Hormone replacement therapy, calcium and vitamin D3 versus calcium and vitamin D3 alone decreases markers of cartilage and bone metabolism in rheumatoid arthritis: a randomized controlled trial [ISRCTN46523456]" ppsx
... the hands, wrists, and distal part of the feet were obtained at baseline and after 12 and 24 months Forty joints in the hands and feet were scored (in the hands, proximal interphalangeal joints ... HRT, in line with our previous findings of an increase in insulin-like growth factor in the HRT group [41] PICP correlated significantly with CTX-I and COMP and inversely with bone mass in the ... and intra-articular and intramuscular glucocorticosteroid injections were allowed during the study period The patients were not receiving and had not used in the preceding years drugs affecting...
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báo cáo khoa học: " Quantitative 1H NMR metabolomics reveals extensive metabolic reprogramming of primary and secondary metabolism in elicitor-treated opium poppy cell cultures" pptx
... O-Phosphocholine, choline and ethanolamine are involved in phospholipid metabolism, however only Ophosphocholine levels increased in elicitor-treated cultures In contrast, choline and ethanolamine showed ... oldest medicinal plant and produces several pharmaceutically important benzylisoquinoline alkaloids, including the analgesics morphine and codeine, the muscle relaxant and vasodilator papaverine, the ... both benzylisoquinoline alkaloid and hydroxycinnamic acid amide metabolism in opium poppy Tyrosine/DOPA decarboxylase (TYDC), which converts tyrosine and DOPA to tyramine and dopamine, respectively,...
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Báo cáo khoa học: " Monocarboxylate Transporters and Lactate Metabolism in Equine Athletes: A Review" pdf
... accumulation in skeletal muscle of trained and untrained men Acta physiol scand 1984, 122, 331-339 Sahlin K, Broberg S, Ren, JM: Formation of inosine monophosphate (IMP) in human skeletal muscle during incremental ... concentration in the muscle and perhaps also the activity of MCT in muscle membranes 71 References Baker SK, McCullagh KJA, Bonen A: Training intensity-dependent and tissue-specific increases in lactate ... MCT1, and MCT4 in human skeletal muscle Am J Physiol 2000, 278, E571-E579 Dunnett M, Harris RC: Carnosine and taurine contents of type I, IIA and IIB fibers in the middle gluteal muscle Equine vet...
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Báo cáo y học: "The effects of dopamine and epinephrine on hemodynamics and oxygen metabolism in hypoxic anesthetized piglets" potx
... dopamine or epinephrine and was administered all three doses, which were selected in random order as determined by a LatinSquare method Dopamine and epinephrine were infused at doses of 2, 10, and ... VO2, and hepatic DO2 during epinephrine infusion in comparison with the h baseline A significant elevation in hepatic DO2 was found at the final recording obtained during 0.2 µg kg–1 min–1 epinephrine ... dopamine and epinephrine Am J Respir Crit Care Med 1997, 155:32–37 Barrington KJ, Finer NN, Chan WKY: A blind, randomized comparison of the circulatory effects of dopamine and epinephrine infusions...
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Báo cáo khoa học: "Intra-arterial delivery of triolein emulsion increases vascular permeability in skeletal muscles of rabbits" pot
... triolein in the lung [5-8] and brain [9] In a study of increased vascular permeability induced by an infusion of triolein emulsion into the brain [1], MR images reverted to normal signal intensity ... triolein emulsion injection in Page of (page number not for citation purposes) Acta Veterinaria Scandinavica 2009, 51:30 triolein group or normal saline injection in saline group The imaging time ... occur in the brain There are two main types of capillaries: 1) the fenestrated type, as exists in the liver and 2) the continuous type, as exists in the brain, orbit, skin, and muscle In contrast...
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Báo cáo y học: " Module-based multiscale simulation of angiogenesis in skeletal muscle" doc
... (neuropilin-1 and -2) constitute a complex ligand-receptor interaction network, regulating intracellular signaling and determining cellular response [9] In addition, other VEGF proteins, like ... Following invasion of new sprouts into the tissue by extending the leading tip and stalk cell segments, the tip cell continues to migrate in the interstitial space following VEGF gradients and ... grid point defined within the skeletal muscle and passes the values back to the controller to be stored in the voxel field (Grid class) of the “SkeletalMuscle” object (element PO2 is defined in Grid...
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