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developing combination drugs in preclinical studies

Báo cáo sinh học:

Báo cáo sinh học: "Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety" ppt

Hóa học - Dầu khí

... data, including PT-international normalized ratio (PT-INR), T-Bil, serum albumin, alanine aminotransferase (ALT), and a-fetoprotein (AFP), were examined before plasma exchange or rh-HGF administration ... decrease, during the HGF dosing period Intravenous rh-HGF was well tolerated in all patients with FH or LOHF Preclinical safety studies revealed that a decrease in BP during rh-HGF infusion and ... infusion and renal toxicity induced by repeated rh-HGF dosing, including an increase in urinary excretion of albumin, were potential adverse events in a human study In the phase I/II study of...
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Scientific report:

Scientific report: "The awareness of people about the risks of plant protection drugs in vegetable production: case studies in Hanoi and Thai Binh" ppsx

Báo cáo khoa học

... was conducted in Dang Xa, Le Chi communes in Hanoi city and Thai Giang and Thuy Son in Thai Binh province Hanoi city is a major vegetable-producing region, whereas, Thai Binh province is representative ... reported facing risks were less than 8%, the situation in Thai Binh province seems more serious than those in Hanoi City 3.1.3 Reasons for pesticides causing human risks Main reasons causing pesticide ... or insufficient protective equipment while using pesticides (Table 6) People working nearby spraying Hanoi city Thai Binh province 17 Number of applicators reported 17 sites (weeding, harvesting,...
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Developing service VOIP in Viet Nam

Developing service VOIP in Viet Nam

Quản trị kinh doanh

... meeting QoS fixed, RSVP will send periodically a requirement of prior keeping under prior keeping line of transmission line newscast Precise prior keeping line attained owing to information in ... equal - Padding (P.1 bit) when being installing, it will determine RTCP information package, including some octet added at end part of control information the latest octet of padding part, will ... managimg the delivery of voice information using the Internet Protocol(IP) In general, this means sending voice information in digital form in discrete packets rather than in the traditional circuit...
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Developing Writing Skills in a Foreign Language via the Internet.doc

Developing Writing Skills in a Foreign Language via the Internet.doc

Tư liệu khác

... sequencing (alternating pattern or point by point) With two subjects in mind, chunking separately presents all the points and details of the one subject Then the next section discusses and includes ... decided upon, each group member independently searches the Internet for the required information Having found the pertinent information and written their information into a paragraph or two, it is ... specific information concerning Toronto’s precipitation, temperature, and humidity In contrast, sequencing discusses all the pertinent details and supporting evidence for only one point at a...
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Tài liệu Developing Residency Training in Global Health: A Guidebook ppt

Tài liệu Developing Residency Training in Global Health: A Guidebook ppt

Sức khỏe giới tính

... financial difficulties and 16 scheduling (82% and 52%) Difficulties in creating and sustaining international 11 partnerships, establishing and maintaining institutional support, and evaluating ... schools have begun offering formal training in global health As this training increases, so will the demand for continued and more specialized training during residency Effects of International Electives ... hospital or clinic in Tanzania, delivering babies in the bush, working within a PEPFARfunded AIDS center, weighing infants in feeding centers, or simply attending a community meeting organized...
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Tài liệu Executive coaching: Developing managerial wisdom in a world of chaos doc

Tài liệu Executive coaching: Developing managerial wisdom in a world of chaos doc

Du lịch

... OF TRAINING The sixth challenge for consultants derives directly from the previous point Very few people in the change management industry have formal training or experience in helping individuals, ... traditional departments of institutions are listed, such as research and development, engineering, manufacturing, marketing, purchasing, human resources, finance, safety, planning, maintenance, communications, ... focus on individuals or groups More information about specific coaching methods will be provided in subsequent chapters, but readers must keep in mind that coaching is evolving as a subdiscipline...
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Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States pdf

Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States pdf

Sức khỏe phụ nữ

... regimens, including those with zidovudine alone; zidovudine plus lamivudine; single-dose nevirapine; and single-dose nevirapine combined with either short-course zidovudine or zidovudine/lamivudine.3-12 ... to elimination of perinatal transmission in the United States include the continued increase in HIV infection in women of childbearing age;12 absent or delayed prenatal care, particularly in women ... In general, combination regimens are more effective than single-drug regimens in reducing perinatal transmission In addition, for prevention of perinatal transmission, administration of ARV drugs...
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Business Process Analysis Worksheets and Guidelines: Procedures for Developing Business Processes in ebXML v1.0 docx

Business Process Analysis Worksheets and Guidelines: Procedures for Developing Business Processes in ebXML v1.0 docx

Tài chính doanh nghiệp

... business area? According to the [UMM] the following guidelines are to be used in defining a business area: • The business area can be defined by the stakeholders that have direct or immediate indirect ... identify the information requirements for the business documents specified in the business transactions 11.2 Guidelines The first step in specifying business documents in a business process and information ... understanding of the business domain, • To understand the daily business in the business domain independent of any technical solution, • To create categories to help partition the business domain that...
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Báo cáo khoa học: Insertion of the plant photosystem I subunit G into the thylakoid membrane In vitro and in vivo studies of wild-type and tagged versions of the protein doc

Báo cáo khoa học: Insertion of the plant photosystem I subunit G into the thylakoid membrane In vitro and in vivo studies of wild-type and tagged versions of the protein doc

Báo cáo khoa học

... trypsin, probed with antibodies directed against PSI-G, PSI-K (intrinsic membrane protein, stromal loop), PSI-O (intrinsic membrane protein, luminal loop) and PSI-D (extrinsic membrane protein, ... disrupting protein–protein interactions within PSI, or by altering the conformation of the loop His-tags were employed in a topological study of the major light harvesting chlorophyll a ⁄ b binding ... are shown in Fig 4C Interestingly, both tags are recognized more efficiently in the context of the PSI-G loop region than at the C-terminus Topology of PSI-G in vivo In order to examine the topology...
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Báo cáo khoa học: In vivo studies of altered expression patterns of p53 and proliferative control genes in chronic vitamin A deficiency and hypervitaminosis pot

Báo cáo khoa học: In vivo studies of altered expression patterns of p53 and proliferative control genes in chronic vitamin A deficiency and hypervitaminosis pot

Báo cáo khoa học

... specific binding was determined by the relative intensity of ethidium bromide fluorescence when compared to the input control Our data show that the RAR binding was almost undetectable in vitamin A-deficiency ... controls, while in acute hypervitaminosis the binding was significantly higher These changes in the RAR–DNA binding is not due to different levels of the retinoic acid receptor induced by the treatment, ... of p53 protein was significantly increased in the liver and lung from vitamin A-deficient rats that in controls c-Jun protein was significantly decreased in vitamin A-deficient rats In the liver...
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Báo cáo

Báo cáo " How to foster learner autonomy in country studies at Faculty of English - Hanoi National University of Education? " docx

Báo cáo khoa học

... promoting them to reinforce their active learning process The approaches which have been well applied in our teaching and learning Country Studies (namely British Studies and American Studies) ... idea of keeping portfolio is delivered by the teachers, the learners are entirely self-determined in perfecting its content The learners are in charge of exchanging what kind of information, ... Country Studies in particular References [1] D Little, Learner autonomy 1: Definitions, issues and problems, Dublin: Authentik 1991 [2] D Boud (ed.), Developing student autonomy in learning, Kogan...
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Báo cáo khoa học: Bridging the gap between in silico and cell-based analysis of the nuclear factor-jB signaling pathway by in vitro studies of IKK2 ppt

Báo cáo khoa học: Bridging the gap between in silico and cell-based analysis of the nuclear factor-jB signaling pathway by in vitro studies of IKK2 ppt

Báo cáo khoa học

... lL; prewarmed in a water bath at 37 C) was dispensed into each well and incubated for 15 (prewarming xative is critical to maintaining cell integrity) After 15 min, the plates were inverted to ... ndings indicate that substituting previously reported kinetic data in the original model with the experimental data determined here results in an oscillatory pattern analogous to that seen in ... (TNF-a) and interleukin-1a (IL-1a), thus initiating numerous and diverse intracellular signaling cascades, most of which activate the IkappaB kinase (IKK) complex This crucial component in the NF-jB...
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Master of Science in Economics: Master of Science in Advanced Studies in Economics potx

Master of Science in Economics: Master of Science in Advanced Studies in Economics potx

Cao đẳng - Đại học

... background in economics, a keen interest in recent analytical developments in economics and the desire to work in research positions in business, in national and international institutions and at universities, ... a strong interest in pursuing an academic career and/or in undertaking research in economics The programme builds on undergraduate studies in economics To supplement their previous studies, students ... from one of the following two groupings: - a university Master’s degree in Economics, Business Economics or Business Engineering awarded by the Faculty Economics and Business at KU Leuven or...
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An Introduction to Drugs in Sport pptx

An Introduction to Drugs in Sport pptx

Du lịch

... hereafter invented, including photocopying and recording, or in any information storage or retrieval system, without permission in writing from the publishers British Library Cataloguing in Publication ... Library of Congress Cataloging in Publication Data Waddington, Ivan An introduction to drugs in sport : addicted to winning? / by Ivan Waddington and Andy Smith p cm Doping in sports I Smith, Andy ... performance-enhancing drugs Focusing on drug use within elite sport, the book offers an in- depth examination of important contemporary themes and issues, including:      the history of drugs in sport...
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Savings accounts for young people in developing countries: Trends in practice potx

Savings accounts for young people in developing countries: Trends in practice potx

Ngân hàng - Tín dụng

... financial inclusion and development outcomes For this reason and others, including increasing recent attention in the microfinance industry to savings, youth savings are a hot topic In the face ... remains unclear as to whether they actually increase average savings balances The second type of incentive, financial, are much less common than in- kind incentives; relatively few financial institutions ... issues, including a greater willingness to decline unwanted sexual activity and insist on condom use Studies from India (Mensch et al., 2004) have found similarly encouraging results In Allahabad in...
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Báo cáo

Báo cáo " Post - systemic - functional achievements in language studies and applications to the postgraduate courses structuring syllabus " pptx

Báo cáo khoa học

... fundamental principle of cognitive linguistics in the theory of linguistic meaning In Cognitive linguists' terms, meanings not exist independently from the people who create and use them (i.e meaning is ... relations in combining semantic units including autonomy and dependence, conceptual combination, apposition and parataxis; as well as the existing symptomatic relations in phonology in English ... vision and imagination need careful and empirical investigation in years to come Recent studies of cognitive linguistics in Vietnam In Vietnam, together with the advances in linguistic studies of...
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Role of Non-Steroidal Anti-Inflammatory Drugs in Gynecology potx

Role of Non-Steroidal Anti-Inflammatory Drugs in Gynecology potx

Sức khỏe phụ nữ

... in pain reduction 30-40% in bleeding reduction Up to 82% pain reduction, up to 57% in bleeding reduction Up to 48% in pain reduction Menorrhagia Pain/heavy bleeding associated with intrauterine ... progesterone releasing intra-uterine system (Progestasert oral contraceptive pill), but most studies were underpowered [10] Pain or Heavy Bleeding Associated with Intrauterine Device Intrauterine device ... of prostaglandin synthesis within the fetal membranes at term [23] The increase in prostaglandin during labor causes increased uterine contractility and inhibitors of prostaglandin synthesis delay...
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DEVELOPING YOUR CAREER IN SURVEYING pot

DEVELOPING YOUR CAREER IN SURVEYING pot

Quản lý dự án

... Course Listings – February 2012 BSc Hons Surveying with routes to Building Surveying and Quantity Surveying (BS) (QSC) MA Housing Studies (HOUS) Graduate Diploma in Surveying (Building Surveying) (BS) ... decision support information, interpretation and application, plus post qualification education and standards • Exploring training and development opportunities • Building and maintaining relationships ... Depending on which area you decide to specialise in you could become involved in planning and creating cities, protecting the environment, designing the latest Sony Playstation game, helping to...
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DEVELOPMENT OF STUDENTS’ ENGLISH FOR SPECIAL PURPOSES COMPETENCE IN TOURISM STUDIES AT TERTIARY LEVEL potx

DEVELOPMENT OF STUDENTS’ ENGLISH FOR SPECIAL PURPOSES COMPETENCE IN TOURISM STUDIES AT TERTIARY LEVEL potx

Quản trị kinh doanh

... 2006; 2004) Developing intercultural competence is a rather slow learning process, which includes learning a foreign language, intercultural training and gaining experience from meeting people ... the educator in defining the aim of the studies and in strengthening the motives, selecting appropriate teaching-learning methods, mastering the content, analysing the expected and gained results ... additional information and improving the teacher’s knowledge Willingly participates in group work involving other students as well Independent Willingly works in pairs, takes the leading role in pair...
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