detection of cocaine and its metabolites in breast milk
Hydraulic modeling of open channel flows over an arbitrary 3-d surface and its applications in amenity hydraulic engineering
Ngày tải lên :
06/11/2012, 10:35
... depth-averaged
model in a nonorthogonal curvilinear coordinates for prediction of flow pattern in
meandering channel with 60
o
and 90
o
bend, and also with compound meandering channel.
In this study, ... concept of simple Rankine vortex that including
two parts: free vortex in outer zone and forced vortex
in inner zone (Townson 1991)………………………………………33
Figure 4.5 Definition of coordinate components……………………………….36 ... water surface profile into vertical intake. In this regard, the model showed its
applicability in computing the flow into intake with air-entrainment.
The model was also applied to investigate...
- 127
- 595
- 0
Expansion and its realization in the short story “the law of life” by jack london
Ngày tải lên :
29/01/2014, 14:44
... beginning of the story, the main
character was introduced “an old Indian named Koskoosh” and the story is told from
the point of view of this character. In the text, one can find many types of ... determine the experiential meaning,
interpersonal meaning and textual meaning, respectively.
In order to understand a text, apart from its register, it is necessary to understand the
genre of ... would like to analyze a
randomly chosen text in terms of expansion to see how the findings can help to
understand some features of the text and the intention of the writer. In this thesis, the
text...
- 43
- 921
- 0
Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
Ngày tải lên :
14/02/2014, 19:20
... full-length
v-KIND; DKIND1, deletion of KIND1;
DKIND2, deletion of KIND2; DKIND1 + 2,
deletion of both KIND1 and KIND2; DRasN,
deletion of RasN; DGEF, deletion of
RasGEF; KIND1, KIND1 domain; KIND2,
KIND2 ... v-KIND KIND2 binding resides within
residues 702–744 of MAP2.
Residues 456–487 in the KIND2 domain of v-KIND
contain the core MAP2 binding module
To identify the core MAP2-binding site within ... sequence for v-KIND binding.
To evaluate the v-KIND KIND2-binding specificity
of residues 702–744 of MAP2, we performed a pull-
down assay of combinations of EGFP-fused KIND1
or KIND2 of v-KIND with...
- 11
- 658
- 0
Tài liệu Báo cáo khoa học: Modulation of a-synuclein aggregation by dopamine in the presence of MPTP and its metabolite pptx
Ngày tải lên :
14/02/2014, 19:20
... line), in the presence of
100 l
M neurotoxin (
•
, dotted line), in the
presence of 200 l
M neurotoxin ( , dotted
line) and in the presence of neurotoxin and
50 l
M dopamine (h, dashed line).
Modulation ... occur in the brain include
selective loss of dopaminergic neurons in substantia
nigra pars compacta and appearance of Lewy bodies
consisting of aggregated protein, mainly a-synuclein, in
Keywords
amyloid; ... pooled and
the amount of protein was determined by the bicinchoninic
acid assay [38] using bovine serum albumin as a standard
protein. The pooled eluate fractions were dialysed against
water and...
- 11
- 754
- 0
Tài liệu Báo cáo khoa học: A novel splice variant of occludin deleted in exon 9 and its role in cell apoptosis and invasion docx
Ngày tải lên :
18/02/2014, 18:20
... level
increased in Occ
WT
-overexpressing cells, and that
2-APB inhibited the effects of Occ
WT
. Therefore,
the increase in intracellular calcium may explain the
induction of apoptosis and reduction ... additional
occludin variant deleted in exon 9 (Occ
DE9
). On the
basis of a comparative analysis of the involvement of
wild-type occludin (Occ
WT
) and variant occludin in
apoptosis and invasion, as determined ... as one of the
mechanisms of this regulation. On the basis of the
above findings, our research provides new insights into
the role of exon 9 in the regulation of apoptosis and
invasion in liver...
- 12
- 613
- 0
Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx
Ngày tải lên :
19/02/2014, 06:20
... obtained from injections of the metal into a solution of
the protein. Typically an initial injection of 2 lL copper
chelate solution was followed by a further 29 injections of
4 lL of Cu(II) into ... stage of tetramerization. Possibly, loss of
copper binding could still allow domain swapping to
occur. It is of interest that a N-terminally truncated pri-
on protein, lacking the copper binding ... Ratio
kcal/mole of injectant
kcal/mole of injectant
kcal/mole of injectant
kcal/mole of injectant
kcal/mole of injectant
kcal/mole of injectant
-2
0
-1
-0.5 0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5 5.0
Stefin...
- 14
- 586
- 0
Tài liệu Báo cáo khoa học: Biochemical characterization of human 3-methylglutaconyl-CoA hydratase and its role in leucine metabolism docx
Ngày tải lên :
19/02/2014, 07:20
... using
crotonyl-CoA as a substrate [15]. The gene encoding
this bifunctional protein was named AUH (‘AU bind-
ing homolog of enoyl-CoA hydratase’). The RNA-
binding activity of the human protein ... mutations in the AUH gene. This indi-
cated that AUH, in addition to its RNA binding func-
tion, must play an important role in leucine catabolism.
AUH was overproduced in E. coli and characterized
by ... inclu-
ding equilibration, was 10 min. A splitter between the
HPLC column and the mass spectrometer was used, and
100 lLÆmin
)1
of eluent was introduced into the mass spec-
trometer. A LCT TOF...
- 11
- 625
- 0
Tài liệu Báo cáo khoa học: Inhibitory properties of cystatin F and its localization in U937 promonocyte cells ppt
Ngày tải lên :
19/02/2014, 17:20
... process
regulating its inhibitory properties.
Screening of proteases for their inhibition showed
that cystatin F is different from other cystatins, both
in terms of specificity and strength of binding to ... Cystatins are generally rather non-
selective inhibitors. An interesting feature of cystatin
F is the 100-fold stronger inhibition of cathepsins F,
L, and V than of cathepsin S. Cathepsin S is ... cystatin C is the most
discriminating residue for binding to cathepsins B, H,
L, S [24]. No L9K mutants of cystatin C have been
prepared yet to study the effect of incorporating the
Cystatin F in...
- 11
- 621
- 0
Tài liệu Báo cáo khoa học: Inorganic pyrophosphatase in the roundworm Ascaris and its role in the development and molting process of the larval stage parasites doc
Ngày tải lên :
20/02/2014, 11:20
... concerning the kinetics and properties of the
enzyme. More strikingly, we show a novel role of the PPase
enzyme in the development and molting process of A. suum
larvae in vitro.
Materials and methods
Parasites
Adult ... V
max
(maximum velocity)
values were determined by incubating the diluted recombin-
ant proteins in the standard reaction mixture in the presence
of increasing concentrations of PP
i
(0.05–0.5 m
M
)at55°C.
Data ... Diluted recombinant proteins were run in the
standard reaction mixture (as described in Materials and methods) for
PPase assays at 55 °C, in the presence of increasing concentrations of
PP
i
(0.05–0.5...
- 13
- 691
- 0
Báo cáo khoa học: Expression of cholinesterases in human kidney and its variation in renal cell carcinoma types pdf
Ngày tải lên :
06/03/2014, 22:21
... erythrocytes in the extent of binding with the
lectins concanavalin A, Lens culinaris agglutinin
(LCA), and Ricinus communis agglutinin (RCA)
(Fig. 3), ruled out the blood origin and supported the
renal ... butyrylcholinesterase activity
assayed in kidney. This proposal is in agreement
with the cytochemical staining of acetylcholinesterase
in the capsule of Bowman [41] and of acetylcholines-
terase and ... appreciable
increase in butyrylcholinesterase activity of chRCC,
cRCC, and RO, instead of its invariability (Table 1),
should have been expected, along with a robust
increase in the proportion of G
4
H
butyrylcholinester-
ase....
- 11
- 474
- 0
Báo cáo khoa học: Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress pdf
Ngày tải lên :
07/03/2014, 12:20
... plasmid
and a virus. Mol Microbiol 34, 217–226.
29 Bradford M (1976) A rapid and sensitive method for
the quantification of microgram quantities of protein
utilizing the principle of protein-dye binding. ... clarified in detail and could play
a key role in the detoxification processes.
In this study we examined the role of Bcp2 in order
to increase the knowledge of the enzymatic activity
involved in the ... important in deter-
mining the level of Bcp2 protein. Similar results are
observed for genes and related proteins involved in
oxidative stress in other microrganisms [24]. Moreover,
the basal level of...
- 11
- 565
- 0
Báo cáo khoa học: Molecular and functional characterization of a novel splice variant of ANKHD1 that lacks the KH domain and its role in cell survival and apoptosis docx
Ngày tải lên :
07/03/2014, 21:20
... identified a protein
containing a single ankyrin repeat that interacts with
HIV-1 viral protein R (Vpr) and we designated this
protein as Vpr-binding ankyrin repeat protein
(VBARP). This interaction ... ankyrin repeat motif-containing proteins play an important role
in protein–protein interactions. ANKHD1 proteins are known to possess
multiple ankyrin repeat domains and a single KH domain with ... Institute, Shanghai, China.
8 Smith RK, Carroll PM, Allard JD & Simon MA (2000)
MASK, a large ankyrin repeat and KH domain-con-
taining protein involved in Drosophila receptor tyrosine
kinase...
- 12
- 561
- 0
Báo cáo khoa học: "Detection of Agreement and Disagreement in Broadcast Conversations" pot
Ngày tải lên :
07/03/2014, 22:20
... train-
ing set by either oversampling the minority class or
downsampling the majority class. In this prelimi-
nary study of sampling approaches for handling im-
balanced data for CRF training, ... using constraint classifiers. In Proceedings
of HLT/NAACL.
D. Hillard, M. Ostendorf, and E. Shriberg. 2003. De-
tection of agreement vs. disagreement in meetings:
Training with unlabeled data. In ... genre in that
it is more interactive and spontaneous, referring to
free speech in news-style TV and radio programs
and consisting of talk shows, interviews, call -in
programs, live reports, and...
- 5
- 405
- 0
Chemical of alumina reactions in aqueous solution and its application in water treatment
Ngày tải lên :
15/03/2014, 23:22
... presence and importance of alumina in the
natural aquatic environment and its growing application
in drinking and wastewater purification, the knowledge
of alumina’s structure and possible interactions ... structure of alumina and its possible interactions with organic and inorganic
compounds in water are of great importance. This is of particular importance in both the understanding of natural ... Poland
´
{
Abstract
Due to the presence and significance of alumina in the natural aquatic environment and its increasing application in drinking
and wastewater purification, the knowledge of...
- 30
- 806
- 0
Báo cáo khoa học: Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer’s disease brain doc
Ngày tải lên :
16/03/2014, 22:20
... FEBS
Levels of mTOR and its downstream targets 4E-BP1, eEF2,
and eEF2 kinase in relationships with tau in Alzheimer’s
disease brain
Xu Li
1
, Irina Alafuzoff
2
, Hilkka Soininen
3
, Bengt Winblad
1
and ... staining in the granule
layers of the dentate gyrus (not shown). In contrast, in
control brain slices there was weak stainings in the
pyramidal neurons of the CA1, CA2, CA3 and the
entorhinal ... proteins with
either polyglutamine or polyalanine expansions in
Huntington disease, Huntington related diseases, and
various forms of a-synuclein associated with Parkinson
disease and synucleinopathies...
- 10
- 376
- 0
- a diminished quality of life and an increase in healthcare costs
- cocaine and its metabolites
- and its treatment in a machine translation system s
- detection of agreement and disagreement
- characteristics of obesity and its related disorders in china
- excretion of cocaine and its metabolites in man
- detection of cocaine and its metabolites
- cocaine and its metabolites in urine
- detection of agreement and disagreement in broadcast conversations
Tìm thêm:
- hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam
- xác định các mục tiêu của chương trình
- xác định các nguyên tắc biên soạn
- khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn
- khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản
- khảo sát chương trình đào tạo gắn với các giáo trình cụ thể
- xác định thời lượng học về mặt lí thuyết và thực tế
- tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam
- điều tra đối với đối tượng giảng viên và đối tượng quản lí
- điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1
- khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam
- khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu
- nội dung cụ thể cho từng kĩ năng ở từng cấp độ
- xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct
- phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ
- mở máy động cơ lồng sóc
- mở máy động cơ rôto dây quấn
- các đặc tính của động cơ điện không đồng bộ
- hệ số công suất cosp fi p2
- đặc tuyến hiệu suất h fi p2