design of prodrugs directed toward glutamine k cysteine s conjugate amp 946 lyase in the kidney
Tài liệu The Benefits of Bank Deposit Rate Ceilings: New Evidence on Bank Rates and Risk in the 1920s (p. 2) docx
... earning assets • Interest received to earning assets The presumption was—and still is—that the higher these ratios, the lower the quality of the bank 's assets and so the higher its risk Gross losses ... measures of gross earnings, two measures of investments as percentages of total assets, and six measures of losses and loans and securities Benston grouped banks by location and examined banks ... To measure asset quality, Cox settled on these four ratios: • Gross losses on earning assets to earning assets • Real estate loans to earning assets • Securities other than those of the U .S government...
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A review on the cd content of rice daily cd intake and accumulation in the kidneys
... ash, Flameless AAS Dry ash, Flame AAS Dry ash, Flame AAS Flameless AAS Wet ash, Flameless AAS Wet ash, Flameless AAS Dry ash, Flame AAS Flameless AAS Wet ash, Flameless AAS Wet ash, Flameless ... Wet ash, Flameless AAS Dry ash, Flame AAS Dry ash, Flame AAS Dry ash, Flame AAS Dry ash, Flame AAS Wet ash,Flameless AAS Wet ash, Flameless AAS Wet ash, Flameless AAS Wet ash, Flameless AAS Flame ... liver of inhabitants of upper Silesia (Poland) Int Arch Occup Environ Health 1993; 65: 57–63 5) Nilsson U, Schütz A, Skerfving S, Mattsson S Cadmium in kidneys in Swedes measured in vivo using...
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Báo cáo khoa học: Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription pptx
... Coexpression of HIPPI and BLOC 1S2 does not increase apoptosis but sensitizes apoptosis induction by staurosporin or death ligand In addition, the expression of BLOC 1S2 is increased in some tumors ... directly or indirectly alters gene expression comes from the observations that caspase-1, caspase-3, caspase-7, caspase-8 and caspase-10 expression is increased in cells expressing exogenous FEBS Journal ... heterodimer and increases apoptosis The role of caspase-1 in apoptosis is not known, but in some conditions it may increase apoptosis Different symbols representing different proteins are shown in the box...
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Báo cáo khoa học: De novo synthesis, uptake and proteolytic processing of lipocalin-type prostaglandin D synthase, b-trace, in the kidneys pptx
... progression of kidney damage In some renal diseases, the increase in the biosynthesis of L-PGDS in the kidney may be a type of adaptation mechanism against kidney 7154 injury An L-PGDS inhibitor, ... D1)22Cys65,167Ala L-PGDS (line 1) Asterisks indicate the two N-glycosylation sites (C) The purified GST-fusion proteins containing the series of amino-terminus-truncated L-PGDS were separated by SDS-PAGE, ... Diagnostics, Mannheim, Germany), according to the manufacturer s instructions SPR analysis The kinetics of binding of MAbs to human L-PGDS were determined by SPR analysis using a Biacore 2000 system...
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Báo cáo sinh học: " Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes" potx
... These previously evaluated single-mutation viruses were included here for the purpose of comparison with viruses containing the other individual mutations as well as combinations of mutations ... animals in each group irrespective of day The limit of detection was 0.5 log10 TCID50/ml d Mean sum of the daily virus titers: the sum of the titers for all of the days of sampling was determined ... virus and performed in vitro and in vivo studies SRS recovered viruses and assisted with in vivo studies PLC contributed to the study design and drafting of the manuscript MHS and BRM supervised...
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báo cáo hóa học: "Impact of gastroesophageal reflux disease on patients'''' daily lives: a European observational study in the primary care setting" doc
... Likert-type scale for which lower scores indicate an increased level of distress and frequency of the problem [12] Statistical analysis Hypothesis testing was not carried out in this study, as ... including the RDQ, GIS and the Gastrointestinal Symptoms Rating Scale, may be one such instrument, providing more accurate and sensitive quantification of the symptoms and the impact of these in ... disturbance scores were consistently higher than scores for other extra-esophageal symptoms across the range of countries in terms of both frequency and intensity (Figures and 5) Similarly to RDQ scores,...
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báo cáo hóa học: " Activation of retinal microglia rather than microglial cell density correlates with retinal neovascularization in the mouse model of oxygen-induced retinopathy" ppt
... in hyperoxia During the hyperoxic phase, the kinetics of the disappearence of the retinal vessels is faster than the kinetics of microglia activation which peaks at P10 Accordingly, activated ... Cells with GFP expression but without lectin staining are microglial cells Vessels remnants are stained with lectin, too (arrows) Discussion Hyperoxic phase In the central zone of OIR retinas, ... antibodies It may be speculated that similar signaling pathways are used in retinal vessel regression during the hyperoxic phase and that retinal vessel regression is induced by hyalocytes rather...
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Báo cáo hóa học: " Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes" docx
... These previously evaluated single-mutation viruses were included here for the purpose of comparison with viruses containing the other individual mutations as well as combinations of mutations ... animals in each group irrespective of day The limit of detection was 0.5 log10 TCID50/ml d Mean sum of the daily virus titers: the sum of the titers for all of the days of sampling was determined ... virus and performed in vitro and in vivo studies SRS recovered viruses and assisted with in vivo studies PLC contributed to the study design and drafting of the manuscript MHS and BRM supervised...
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báo cáo hóa học: " The comparative burden of mild, moderate and severe Fibromyalgia: results from a cross-sectional survey in the United States" pdf
... days over the last weeks and being 75 percent effective in their work-related activities when working with symptoms The mean number of days missed from work during the past weeks also increased ... These results are consistent with other studies reporting substantial health status limitations among FM patients [29,30] and that FM patients have worse SF-36 scores on the subscales of physical ... comprehensively; [13] however, few cross-sectional studies have been conducted that include a comprehensive assessment of the burden of illness associated with FM in the US Previous US studies have...
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Báo cáo lâm nghiệp: " Early development and nutrition of Norway spruce (Picea abies (L.) Karst.) seedlings on different seedbeds in the Bavarian limestone Alps – a bioassay" ppsx
... methods Therefore, the non-parametric Kruskal-Wallis-H-test (software package SPSS 12.0 for Windows, SPSS Inc.) was used to prove significant differences of the three types If significant differences ... mineral soils Also weights of spruce needles in organic substrates were significantly higher than for seedlings grown in mineral soil substrates Seedlings in decayed wood furthermore had the significantly ... types among the two study sites, as well as among seedlings grown on them in a pairwise comparison Due to non-significant differences among samples, the three substrates obtained from the two sites...
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Báo cáo khoa hoc:" An expression of mixed animal model means equations to account for different and variances in the base" pps
... vector of the Mendelian sampling effects (s) of animals with known parents, such that where P is a matrix relating non-base animals among themselves; and Q is the incidence matrix relating base animals ... = = = DISCUSSION presented in this paper permit us to obtain a general expression predict breeding values using animal models when the means and variances of breeding values in the base generation ... assumptions concerning the variance of breeding values of base animals A numerical example is given THEORY The usual animal model expression can be written as: where y is the vector of records; b is the...
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Báo cáo y học: "Use of a population-based survey to determine incidence of AIDS-defining opportunistic illnesses among HIV-positive persons receiving medical care in the United States" ppsx
... multiplying the sampling weight of the provider and the sampling weight of the patient within the provider as previously described [6] These weights were used to estimate the numbers of patients in ... of patients within selected providers [17] The sampling strategy in MMP is based on the methods used in the study reported here, but aims to improve these methods by using equal probability sampling ... included in the patient sampling frames prepared by the providers, which would have resulted in an incomplete sampling frame at the second stage – but not necessarily in any bias, unless not being included...
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báo cáo khoa học: "Successful treatment of a T4 lung tumor with vertebral body invasion using fiducial markers in the thoracic spine for image-guided radiation therapy: A case report" pps
... use of spinal markers also limits the possibility of human error during the matching process, such as matching to the wrong vertebral body, which can occur when using other forms of IGRT The case ... (PET) scan showed hypermetabolic uptake in the mass but no mediastinal or distant metastases The patient was diagnosed with stage IIIA T4, N0, M0 lung cancer on the basis of the AJCC Cancer Staging ... number of institutions, including the University of Pittsburgh [3] and Stanford University [4] The implantation of markers involves an invasive procedure with associated risk Gerstzen et al [5]...
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báo cáo khoa học: " Seroprevalence of select bloodborne pathogens and associated risk behaviors among injection drug users in the Paso del Norte region of the United States – Mexico border" ppt
... With the exception of the tests for HBsAg and initial syphilis screening, the DSHS laboratory used the same tests as SLD Testing for HBsAg was done using ETIMAK-2 PLUS (DiaSorin, Inc., Stillwater, ... friends and 30.9% with their main sex partner [9] While these The question of how to reduce the risk of bloodborne disease transmission among IDUs in this region raises interesting issues for consideration ... design the study, assist with implementation and interpretation of findings SA supervised implementation and helped with interpretation of findings SM helped design the study and supervise aspects...
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Báo cáo y học: "Successful resuscitation of an elderly man with deep accidental hypothermia using portable extracorporeal circulation in the emergency department: a case report" pps
... rewarming and hemodynamic support, and a less-invasive procedure in a safer, more prompt fashion Conclusion While most successful resuscitations from DAH occur in the young, the successful resuscitation ... weeks after admission he was discharged to a long-term acute care hospital Subsequently he was transferred to a nursing home where he was still residing months after hospital discharge Discussion ... direct vision Patient was in sinus rhythm, HR 87/minute 1330 Patient was successfully weaned from CPS after 270 minutes of bypass with BP 140/60, HR 80/minute, in sinus rhythm, and temperature of 37°C...
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Báo cáo y học: "Use of a highly sensitive strand-specific quantitative PCR to identify abortive replication in the mouse model of respiratory syncytial virus disease" pptx
... mRNAs are synthesised by the viral RNA polymerase, these mRNAs make use of host-cell machinery to synthesise viral proteins Genome replication occurs via the production of a positive sense replicative ... specificity of the reactions was assessed by spiking positive and negative sense RSV RNA standards into naïve mouse lung RNA and using both positive and negative strand-specific reagents to measure RSV ... tag-specific primer during QPCR cycling (Table 1) The use of this tag is designed to reduce detection of cDNAs synthesised due to RNA self-priming in the reverse RSV infection in vitro To investigate...
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Báo cáo khoa học: " Development of liver dysfunction under artificial nutrition: a reason to modify nutrition therapy in the intensive care unit" docx
... use of biomarker analysis Which consequences have to be drawn in clinical practice? Should we retard or even skip artificial support in adult ICU patients? On the basis of present knowledge the ... metabolism Interestingly, age and gender, weight, range of clinical scores, type of primary diagnosis, necessity for mechanical ventilation, and the composition of the lipid emulsion used within TPN ... be an integral component of modern medical therapy In many cases the primary disease is the decisive cause of the development of liver dysfunction; intravenous or even enteral nutritional support...
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MECHANISMS OF CYTOSKELETAL DYSREGULATION IN THE KIDNEY PROXIMAL TUBULE DURING ATP DEPLETION AND ISCHEMIA
... components of the actin cytoskeletal alterations that are observed; the first is the breakdown of actin filament-containing structures including microvillar actin bundles and stress fibers, with the ... meanwhile, Syk, another Src family kinase, also binds with and tyrosine-phosphorylates cortactin in platelets upon thrombopoietin stimulation [70] Two serine residues (Ser-405, Ser-418) in the prolinerich ... region by interaction with different proteins There is a dense meshwork of actin and associated proteins as well as intermediate filaments in the terminal web These meshwork structures are oriented...
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Nutritional status and effectiveness of interventions to reduce stunting malnutrition among children under 5 years old in the costal plain area, nghe an province
... absorption of zinc due to the decrease in zinc transport protein synthesis in intestine Relationship mothers’ knowledge and practice The results showed that factors reduced the risk of stunting including: ... Structure of the thesis: the thesis consists of 134 pages including Introduction (3 pages); Chapter Overview (44 pages); Chapter Subjects and research methods (20 pages); Chapter Research results ... concretized the above solution groups as follows: Chapter SUBJECTS AND METHODS STUDY DESIGN : steps in conducting the study Step 1: A cross-sectional descriptive study to describe the child malnutrition...
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Role of misfolded nuclear receptor co repressor (n cor) induced transcriptional de regulation in the pathogenesis of acute monocytic leukemia (AML m5
... diseases71,72, ophthalmic tissue diseases73-78, skeletal muscle diseases79-83, connective tissue diseases84-86, Atherosclerosis87-89 as well as in cancers The basis for pathogenesis of most of ... his invaluable input on some of the work done in this thesis and for taking the time to vet my thesis; A/Prof Chng Wee Joo and Prof Norio Asou for their kind assistance with the patient samples ... Alzheimer s disease and Parkinson s disease6870 , however recent studies are beginning to reveal new evidences of the involvement of protein misfolding in a multitude of other diseases such as in lung...
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