design conduct and monitoring of safety toxicity studies in animals
Báo cáo y học: " Design, assembly, and validation of a nose-only inhalation exposure system for studies of aerosolized viable influenza H5N1 virus in ferrets" ppt
... agent is added to the starting material and collector fluids in the impingers to reduce bubbling Validation of system engineering and function Initial operating parameters of the exposure system ... complicate and confound understanding by measuring both live and inactivated agents Although the effect of the collection process on the viability of the entrained agent in the impingers can only be inferred, ... system flow rate monitoring and control Page of 12 Sampling system The sampling system consists of two model 7531 midget impingers (Ace Glass Incorporated, Vineland, NJ) connected in series, with...
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Design, fabrication, and characterization of a solenoidsystem to generate magnetic field for an ECR proton source
... than μS/cm) having inlet temperature of 27◦ C Based on the length of the conductor, water pressure drop and flow, the inlet and outlet connections were provided Total five inlet and five outlet ... circulation) The insulation to the conductor layer was provided using ‘H’ class fibreglass insulation tape The diameter of the bore was 150 mm so that plasma chamber including water-cooling jacket and high ... rate liter/min and pressure 3·5 kg/cm2 was maintained The rise in temperature was restricted to less than 20◦ C The inductance and resistance of the solenoid coils were measured using precision...
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Tài liệu Design and optimisation of conformal cooling channels in injection muolding tools docx
... I-DEASTM software for prototyping and simulation The study is on going and hopefully would culminate in the suggestion of the level of proficiency required using virtual models in deciding moulding ... obtain an optimum mould design, especially on sizing and positioning of cooling channels With the same instrument, optimal processing conditions in the cooling operation was found, minimising ... mould and it is compensated by the incoming material; the remainder of the shrinkage takes place sometime following the production of the part [1] 1295 Fig Pressure history during injection moulding...
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Design, Construction and Operation of the Floating Roof Tank pot
... buoyancy of floating roofs due to liquid in pontoon • Roof drain leaking or being blocked • Derailing of rolling ladder on top of a floating roof • Buckling of the supporting legs of a floating roof ... loading including hydrostatic pressure, wind loading and seismic loading In the roof design, it consists of two sections, that is (1) roof stress design and the (2) roof fitting and accessories design ... • Jamming of roof seals due to (progressively increasing) out -of- roundness of the tank shell • Roof seals giving a gap as the result of out -of- roundness and/ or tilting of the roof • Loss of buoyancy...
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DESIGN AND DEVELOPMENT OF MEDICAL ELECTRONIC INSTRUMENTATION A Practical Perspective of the Design, Construction, and Test of Medical Devices docx
... noninverting follower, which can be analyzed in a similar manner The setting of the noninverting input at input voltage Vin will force the same potential at point A Thus, Vin iin ϭ ᎏᎏ Rin and ... Vout Ϫ Vin if ϭ ᎏᎏ Rf But in the noninverting amplifier iin ϭ iout, so by replacing and solving for Vout, we obtain Rf Vout ϭ ϩ ᎏᎏ Vin Rin The voltage gain in this case is Rf G ϭ ϩ ᎏᎏ Rin A special ... Guard Ring IN- 4 In1 In2 In3 In4 10 ICxC + OUT-4 J1-25 J1-26 J1-27 J1-28 Out1 Out2 Out3 Out4 In1 In2 In3 In4 J2-22 J2-13 J2-21 J2-14 - IC8 TLC27L4 11 J1-29 J1-30 J1-31 J1-32 In1 In2 In3 In4 Out1...
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control and monitoring of chemical batch reactors advances in industrial control
... Electrical and Computer Engineering National University of Singapore Engineering Drive Singapore 117576 Singapore Professor I Yamamoto Department of Mechanical Systems and Environmental Engineering ... University Kingston, Ontario K7L 3N6 Canada Professor T.H Lee Department of Electrical and Computer Engineering National University of Singapore Engineering Drive Singapore 117576 Singapore Professor ... Springer is part of Springer Science+Business Media (www.springer.com) Advances in Industrial Control Series Editors Professor Michael J Grimble, Professor of Industrial Systems and Director Professor...
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guide to the design, selection, and application of screw feeders
... solids handling, he enjoys a ‘hands-on’ attitude to powder handling problems He has introduced various design innovations and patents in the field and designed various instruments for measuring flow-related ... Professional Engineering Publishing (publishers to the Institution of Mechanical Engineers) offers a valuable and extensive range of engineering books, conference and seminar transactions, and prestigious ... flighting and differing geometrical forms used for mixing duties, and the like Screws gained extensive use in agriculture for grain handling, both as separate units and as integral parts of equipment,...
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Báo cáo hóa học: " Research Article Design, Analysis, and Performance of a Noise Modulated Covert Communications System" ppt
... same power and frequency range is shown in Figure In the simulation, the bandwidth of bandpass filter is 40 MHz (BL = 20 MHz), the bandwidth of signal BS is 970 MHz, and the bandwidth of the channel ... results in (25), and the results are shown in Figures and In the simulation, both the SNRV and the SNRH terms are equal, and the bandwidth of the antenna is 10 MHz wider than the bandwidth of the ... processing is implemented on Lyrtech SignalWAVe DSP/FPGA development boards Using Xilinx ISE 7.0 and the Xilinx and Lyrtech blocksets, the baseband signal processing was designed in the Simulink...
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Báo cáo hóa học: " Research Article Design and Performance of Cyclic Delay Diversity in UWB-OFDM Systems" docx
... Scottland, June 2007 [7] K.-B Png, X Peng, and F Chin, “Performance studies of a multi-band OFDM system using a simplified LDPC code,” in Proceedings of the International Workshop on Ultra-Wideband ... outage probability of UWB-OFDM system with jointly encoding across two subcarriers At outage probability of 10−2 , CDD obtains about 6.3 dB gain and 2.3 dB gain on the CM1 and CM4 channels, respectively ... [12] which includes the effects of multipath clustering and Poisson arrival of multipath components inherited in UWB channels Based on the framework in [12], symbol error rate (SER) and outage...
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Báo cáo hóa học: " Stretching and immobilization of DNA for studies of protein–DNA interactions at the single-molecule level" ppt
... apparent decrease in binding lifetimes (Fig 11B), suggesting that during the sliding the protein maintains registry with the DNA, and does not hop on and off, since the rate of re-binding to the DNA ... methods of stretching and immobilization of DNA molecules using moving interface include spin-coating and air-blowing [57] Both methods rely on fast motion of an air–solvent interface, generated ... We will discuss combing in more detail in section ‘‘Stretching by a moving interface’’ As mentioned in the section ‘‘Introduction,’’ stretching and immobilization of DNA using flow occurs either...
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Design, synthesis and applications of Metal Organic Frameworks
... benzene-1,4-dicarboxylic acid linkers (top inset box) coordinated to zinc ion cluster joints (shown in blue in the bottom inset box) Tunability of the IRMOF framework One of the principle advantages of MOFs over zeolites ... include utilizing nonlinear ligands44 instead of rigid linear dicarboxylates, asymmetrical ligands containing two differing metal-binding groups, or mixtures of two different symmetrical ligands.20,45 ... the case of Cd MOF-1 and Cd MOF-2, they exhibit smaller channels then designed while remaining some degree of porosity Figure 34 Adamentine view of a single fold of framework of Cd MOF-2, which...
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DESIGN, INSPECTION, AND CERTIFICATION OF PRESSURE VESSELS AND PRESSURIZED SYSTEMS pot
... scheduling with PSMO initial and periodic PV/S inspections and tests, (5) performing PV/S tests, (6) creating and maintaining PV/S documentation files, (7) preparing and submitting formal inputs ... contractors owning, using, fabricating, modifying, or maintaining PV/S on JSC property are responsible for: (1) designing and fabricating their PV/S to applicable codes and standards referenced in this ... Tubing is inch nominal in diameter or less, and seamless (3) Tubing is joined using flared fittings (4) Tube bending meets bend radius specified in table 7-2 (5) Tubing and associated fittings...
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Báo cáo khoa học: "The safety and efficacy of gamma knife surgery in management of glomus jugulare tumor" pptx
... presence of a middle ear mass Significant ear pain is uncommon Involvement of the inner ear produces vertigo and sensorineural hearing loss [11] Cranial nerve involvement produces hoarseness and dysphagia ... Ataxia and brain stem symptoms may also develop Involvement of the dural sinuses may mimic sinus thrombosis [11,12] In about 2-4% of cases, the first or leading symptoms are hypertension and tachycardia ... at and years, and 75% at 10 years Six patients (15%) experienced new deficits (hearing loss alone in three, facial numbness and hearing loss in one, vocal cord paralysis and hearing loss in one,...
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báo cáo khoa học: " NorthStar, a support tool for the design and evaluation of quality improvement interventions in healthcare" ppt
... iterative processes of drafting, reviewing and editing The resulting content is simple to read, pragmatic and focused on assisting the user in developing and evaluating the QI intervention In addition, ... browsing NorthStar was 20.6 minutes Participants spent most of the time looking at 'Identifying Determinants of Practice' (8/17; 47%) and 'Designing the Intervention' (6/17; 35%) The levels of ... selection, implementation and evaluation of QI interventions It guides the user on how to identify "determinants of practice" in designing the intervention and on how to design a cluster RCT as...
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Báo cáo y học: "α The role of anti-α-actinin antibodies in the pathogenesis and monitoring of lupus nephritis" pot
... pathogenicity of murine lupus antibodies was dependent on direct α-actinin binding Subsequently, we found that there are ACTN polymorphisms in MRL-lpr lupus mice and that enhanced expression of α-actinin ... anti-α-actinin antibodies in lupus patients was associated with a 2.5-fold increase in the prevalence of LN [14] Finally, levels of anti-α-actinin antibodies correlated with those of anti-DNA ... since in previous studies about 20% of SLE patients had Page of (page number not for citation purposes) increased anti-α-actinin antibodies [5,14] Moreover, the lack of a difference in α-actinin...
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Báo cáo khoa học: " Geographical Information System (GIS) as a Tool in Surveillance and Monitoring of Animal Diseases" potx
... areas of diseases as shown by Staubach et al (1998) in case of Echinococcus multilocularis in foxes Description of the sources of the data used in the GIS in the field of veterinary epidemiology in ... obvious and as a by-product of introduction of GIS, the system of collecting, storing and managing data can be improved Last but not least, keep in mind: The maps will never be better than the original ... The structure of a Geographical Information System models of the real world using points, lines and polygons Vector digitising captures a point as a x, y co-ordinate, while a line is captured...
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DESIGN, SYNTHESIS AND STUDY OF DNA-TARGETED BENZIMIDAZOLE-AMINO ACID CONJUGATES
... DNA minor groove binding ligands 1.3 DNA Ligand Binding Modes There are several DNA-ligand binding modes, including (1) exterior surface binding which is mainly electrostatically driven, (2) intercalation, ... increased binding affinity and specificity This thesis will focus on utilizing low molecular weight ligand-DNA interactions of the minor groove in our design of amino acid-benzimidazole-amidine ... for the design of many man-made DNA minor groove binding ligands originates from naturally occurring peptide-based compounds such as netropsin, distamycin, actinomycin, and echinomycin.13-16...
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BS 5588 4 1998 fire precautions in the design, construction and use of buildings
... Scope This part of BS 5588 gives guidance on the design, installation, testing and maintenance in new and existing buildings of systems intended to limit the spread of smoke by means of pressure ... Fire Brigades Union Health and Safety Executive Home Office Institute of Building Control Institution of Gas Engineers Institution of Structural Engineers London Fire and Civil Defence Authority ... that, in the event of fire anywhere in the building, the circuits continue to operate and the cables maintain circuit integrity Wiring systems should either: a) consist of one of the following:...
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BS 5588 4 1998 fire precautions in the design, construction and use of buildings MVAC
... Scope This part of BS 5588 gives guidance on the design, installation, testing and maintenance in new and existing buildings of systems intended to limit the spread of smoke by means of pressure ... Fire Brigades Union Health and Safety Executive Home Office Institute of Building Control Institution of Gas Engineers Institution of Structural Engineers London Fire and Civil Defence Authority ... that, in the event of fire anywhere in the building, the circuits continue to operate and the cables maintain circuit integrity Wiring systems should either: a) consist of one of the following:...
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design, manufacture, and installation of concrete piles
... prevent wings of the grooved edge from breaking off during driving This can be minimized by accuracy in setting, the use of jets to assist driving, and provision of light reinforcing in the wings ... including handling, storing, and transporting For lifting and transporting stresses, the analysis should be based on 150% of the weight of the pile to allow for impact Pickup and blocking points ... stresses include those the pile may be subjected to before being put into service (such as handling and driving stresses) and stresses resulting from in- service loading of short and intermittent...
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