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describe the structure of a network

Báo cáo khoa học: Unravelling the functional interaction structure of a cellular network from temporal slope information of experimental data docx

Báo cáo khoa học: Unravelling the functional interaction structure of a cellular network from temporal slope information of experimental data docx

Báo cáo khoa học

... however,only applicable to the case when for each node there areas many parameters as the number of overall network nodes and these parameters do not directly affect the corresponding node. The fundamental ... experimental data containing (partially) cor-rect dynamic pattern changes then we can infer the (partial) interaction structure of the underlying cellular network by integrating the analysis results ... without a speci-fic assumption on parameter perturbations for each network node. Basedon these equations, we further describe the available specific informationfrom each part of experimental data...
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Tài liệu Báo cáo

Tài liệu Báo cáo " The meaning and structure of a science fiction story: a sysyemic functional analysis " doc

Báo cáo khoa học

... declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative ... declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative declarative imperative declarative declarative ability/neg. ... anaphoric anaphoric anaphoric exophoric anaphoric exophoric anaphoric anaphoric anaphoric anaphoric exophoric anaphoric anaphoric anaphoric anaphoric exophoric anaphoric anaphoric...
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Tài liệu Báo cáo khoa học: Crystal structure of Klebsiella sp. ASR1 phytase suggests substrate binding to a preformed active site that meets the requirements of a plant rhizosphere enzyme doc

Tài liệu Báo cáo khoa học: Crystal structure of Klebsiella sp. ASR1 phytase suggests substrate binding to a preformed active site that meets the requirements of a plant rhizosphere enzyme doc

Báo cáo khoa học

... a ⁄ b domain than in the a domain [20].This is also reflected in the rigidity of the protein. The atomic displacement factors of the PhyK structure aresmaller for the a ⁄ b domain than for the ... coli phytase, glucose-1-phosphatase and human prostatic-acid phosphatase. The polypeptidechain is organized into an a and an a ⁄ b domain, and the active site islocated in a positively charged ... substrate-freeAppA the C a atoms are 2.41 A ˚apart, whereas for the substrate-free PhyK and the substrate-loaded AppA the averaged distance is only 1.87 A ˚.Distinct conformational changes were observed...
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Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf

Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf

Báo cáo khoa học

... because of the absence of the catalyticsubunit ISP (Table 1). Figure 3A shows that a band of approximately 500 kDa was also found in this mutantstrain when the mitochondrial membranes were ana-lyzed ... were of analytical grade.Yeast strains and growth media The genotypes and sources of the S. cerevisiae strains aredescribed in Table 2. The ISP deletion strain wasprepared in accordance with the ... dimerization of the bc1complex atthis stage (i.e. just after the addition of ISP and Qcr10p).On the other hand, in the transition from the 500 kDaband to the 670 kDa band, a structural rearrangementof...
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Tài liệu Báo cáo khoa học: Insights into the structure of plant a-type phospholipase D Susanne Stumpe, Stephan Konig and Renate Ulbrich-Hofmann ¨ ppt

Tài liệu Báo cáo khoa học: Insights into the structure of plant a-type phospholipase D Susanne Stumpe, Stephan Konig and Renate Ulbrich-Hofmann ¨ ppt

Báo cáo khoa học

... that the calcium-binding event of lower affinity is attributable to the catalytic site of PLDa2, as found for PLDb from A. thaliana [39]. The decrease in PLD activity at concentrationsabove the ... Journal 274 (2007) 2630–2640 ª 2007 The Authors Journal compilation ª 2007 FEBS 2633from the ratio of the forward scattering intensity of the sample and that of the molecular mass standard BSA. The ab ... 2B).Reconstruction of the overall shape of the PLDa2from the X-ray scattering data was achieved by the ab initio modeling program dammin [24]. The superpo-sition of the 10 calculated models (Fig. 3) shows a longish...
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Tài liệu Báo cáo khoa học: ˚ The 1.8 A crystal structure of a proteinase K-like enzyme from a psychrotroph Serratia species docx

Tài liệu Báo cáo khoa học: ˚ The 1.8 A crystal structure of a proteinase K-like enzyme from a psychrotroph Serratia species docx

Báo cáo khoa học

... SPRK also has an aspar-tic acid residue at position at 200, and with the sameconformation as in the two other structures, butAsp200 forms a salt bridge to Lys253 (Ala253 andAsn250 in PRK and ... [18]. The biophysical characteri-zation of SPRK did not reveal the classical cold adap-ted features [19], but still initial comparative studiesshowed that the catalytic turnover was at least ... reported.Results and discussionCrystallization, data collection and refinementCrystals of the catalytic domain of the Serratia prote-inase K (SPRK) grew within a few days to thin hexa-gonal plates growing...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "The Utility of a Graphical Representation of Discourse Structure in Spoken Dialogue Systems" ppt

Báo cáo khoa học

... system. Also, their underlying task (air travel domain) is much simpler than our tutoring task. In addition, the SIH is not always available and users have to activate it manually. Other visual ... hints/de-scribes the answer, each discourse segment has an additional purpose annotation that is displayed when the segment is part of the visible horizon. Auto-collapse. To reduce the amount of infor-mation ... also have an equivalent in a new domain (e.g. displaying the recognized user answer can be the equivalent of the correct answers). Other NM usages can also be imagined: e.g. reducing the length...
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Báo cáo khoa học: Structure of Streptococcus agalactiae serine⁄threonine phosphatase The subdomain conformation is coupled to the binding of a third metal ion pptx

Báo cáo khoa học: Structure of Streptococcus agalactiae serine⁄threonine phosphatase The subdomain conformation is coupled to the binding of a third metal ion pptx

Báo cáo khoa học

... Hospital and Regional Medical Center, Seattle, WA, USAProtein phosphatases are primarily classified on the basis of the type of the amino acid they dephosphory-late, serine ⁄ threonine phosphatases ... fused to an EF-hand motif, and human STP(HsSTP), which has an additional 8 kDa a- helicaldomain at the C-terminus [3,4]. The sizes of the catalytic domains of both PPP andPPM families are well ... kinase and adenylosuccinate syn-thase, but not in S. agalactiae CovR ⁄ CsrR. The motifis located at the surface of the SaPPase (Rantanen,unpublished), and superposition of the prolines allowssuperposition...
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Báo cáo khoa học: Structure of the complex of a yeast glucoamylase with acarbose reveals the presence of a raw starch binding site on the catalytic domain doc

Báo cáo khoa học: Structure of the complex of a yeast glucoamylase with acarbose reveals the presence of a raw starch binding site on the catalytic domain doc

Báo cáo khoa học

... GLU H44 7A forward (5¢- GCAAGTCATTTTGGATGCTATTAATGATGATGGCTC-3¢), GLU H44 7A reverse (5¢- GAGCCATCATCATTAATAGCATCCAAAATGACTTGC-3¢); GLU T46 2A forward (5¢- GAACAACTTAACAGATATGCCGGTTATT CCACCGGT ... as a template. The following oligonucleotides were used: GLUR1 5A forward (5¢-ATTCAAACTATAAAGTTGACGCAACTGACTTGGAAACCTTC-3¢), GLU R1 5A reverse (5¢-GAAGGTTTCCAAGTCAGTTGCGTCAACTTTATAGTTTGAAT-3¢); ... GLUT46 2A reverse (5¢- GGCACCGGTGGAATAACCGGCATATCTGTTAAGTTGTTC-3¢); GLU H44 7A, D45 0A for-ward (5¢-GCAAGTCATTTTGGATGCTATTAATGCTGATGGCTCCTTGAATGAAC-3¢), GLU H44 7A, D45 0A Fig. 7. Adsorption to raw...
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Inside the Structure of Defined Contribution/401(k) Plan Fees: A Study Assessing the Mechanics of the ‘All-In’ Fee pot

Inside the Structure of Defined Contribution/401(k) Plan Fees: A Study Assessing the Mechanics of the ‘All-In’ Fee pot

Quỹ đầu tư

... In the report, Exhibit 3 plots the impact of average account balance and number of plan participants on the ‘all-in’ fee for a variety of combinations of average account balance and number of ... assets to arrive at the ‘all-in’ fee as a percentage of plan assets. Also, each plan’s total dollar fee amount was divided by total participants in the plan to arrive at the ‘all-in’ fee as ... further analysis found that a core specification that allowed average account balances and number of participants (both in logs) to affect fees as a percentage of assets each had separate and...
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Báo cáo khoa học: The oxidative effect of bacterial lipopolysaccharide on native and cross-linked human hemoglobin as a function of the structure of the lipopolysaccharide A comparison of the effects of smooth and rough lipopolysaccharide ppt

Báo cáo khoa học: The oxidative effect of bacterial lipopolysaccharide on native and cross-linked human hemoglobin as a function of the structure of the lipopolysaccharide A comparison of the effects of smooth and rough lipopolysaccharide ppt

Báo cáo khoa học

... to an increase in the rate of the initial fast phase, i.e. oxidation of the a chains. The rates of oxidation are reduced in the presence of chelators of heavy metal cations in most cases. An ... 3A. The rate of auto-oxidation of cross-linked Hb was greaterthan that of Hb A 0,both in the presence and absence of EDTA, as has been observed previously [17]. In addition, the rates of auto-oxidation ... binding of the Hb tetramer to the LPSmolecule makes the heme cavity of the a chains moreaccessible to a water molecule which can then accelerate the displacement of the protonated superoxide anion,...
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Báo cáo Y học: Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIa doc

Báo cáo Y học: Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIa doc

Báo cáo khoa học

... demonstrate the presence of positive charge.Figure 4I shows the bottom face (same as in Fig. 4C) of a van der Waals model of the best structure of RIIa D/D. The central part of this face appears ... two basic sites, the N-terminalamide and His2. Aspartic acids Asp27 and Asp30 showlower mean pK a values than their model pK a values. Thismay be a general property of Asp residues, as it has ... Toexamine the electrostatic character of the structure of RIIaD/D we have predicted mean apparent pK a values, based onPoisson–Boltzmann electrostatic calculations, using anensemble of calculated...
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Báo cáo khoa học: Structure of a trypanosomatid mitochondrial cytochrome c with heme attached via only one thioether bond and implications for the substrate recognition requirements of heme lyase potx

Báo cáo khoa học: Structure of a trypanosomatid mitochondrial cytochrome c with heme attached via only one thioether bond and implications for the substrate recognition requirements of heme lyase potx

Báo cáo khoa học

... compilation ª 2009 FEBS 2831 of the alanine of the AXXCH motif (Ala25) (ingreen) and the unsaturated vinyl group of the heme(cyan) are separated by 3.41 A ˚(as compared with a typical thioether ... 72% similarity. The structuresare remarkably similar overall, and in the details of the heme attachment and heme position. The rmsdbetween the structure of C. fasciculata cytochrome cand S. ... Crystallographic data were collected atbeamline IO2 at Diamond Light Source, UK, and weacknowledge the support of T. Sorensen at Diamondand A. Labrador at the ESRF, France.References1 Barker...
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Báo cáo khoa học: The crystal structure of a xyloglucan-specific endo-b-1,4glucanase from Geotrichum sp. M128 xyloglucanase reveals a key amino acid residue for substrate specificity potx

Báo cáo khoa học: The crystal structure of a xyloglucan-specific endo-b-1,4glucanase from Geotrichum sp. M128 xyloglucanase reveals a key amino acid residue for substrate specificity potx

Báo cáo khoa học

... Reykjavik, Iceland), and were refined by varying the pH of the buffer and the concentration of the precipi-tant. Prior to data collection, a crystal was transferred intoParatone-N (Hampton Research) ... used as a search model. The cns program [19] was used forrefinement against the 20–2.5 A ˚intensity data. A ran-domly selected portion of the diffraction data (5.0%)was used to calculate the ... kinetic parameters The kinetic parameters were determined at various concen-trations of the substrate, tamarind seed xyloglucan (Dainip-pon Sumitomo Pharma, Osaka, Japan), in 50 mm sodiumacetate...
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