deregulation of membrane and receptor mediated signaling by thc therapeutic implications
Báo cáo khoa học: Induction of PPARb and prostacyclin (PGI2) synthesis by Raf signaling: failure of PGI2 to activate PPARb potx
Ngày tải lên :
07/03/2014, 12:20
... components of the prostanoid signaling network are targets of C-Raf signaling pathways Triggering of C-Raf signaling resulted in a dramatic Cox-2 and ERK-dependent increase in the synthesis and release ... mediated by a different PPAR 176 T Fauti et al or even by a PPAR-unrelated event, e.g through stimulation of the SV40 promoter and ⁄ or via the PGI2 membrane receptor IP Unless supplemented by ... of PGE2 and PGI2 which was mainly due to a strong transcriptional activation of the Cox-2 gene (and to a lesser extent of PGIS and mPGES-1) Under the same experimental conditions expression of...
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Báo cáo khoa học: Interactions of ultraspiracle with ecdysone receptor in the transduction of ecdysone- and juvenile hormone-signaling pdf
Ngày tải lên :
23/03/2014, 13:20
... ecdysone receptor in hormone signaling Fig Effect of treatment with hormones, and of receptor expression, on activation of the DR1JHECore reporter promoter (A) Activation of the DR1JHECore promoter by ... RAR ligand 9-cis RA [4] The occurrence of such multiple partner receptor complexes, and their corresponding multiple ligands, raises questions about the integration of multiple ligand signaling ... the mechanisms of invertebrate hormone action is the identification of 1583 Interaction of ultraspiracle and ecdysone receptor in hormone signaling specific receptors that can bind and transduce...
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ENGLISH ADVERBS OF MANNER AND TYPICAL ERRORS MADE BY THE STUDENTS AT LE HONG PHONG SPECIALISED SECONDARY SCHOOL, NAM DINH CITY
Ngày tải lên :
07/09/2013, 13:19
... adverbs of manner? I.1.2 Formation of adverbs of manner I.1.3 Position of adverbs of manner 11 I.1.4 Classification of adverbs of manner 13 I.1.5 The differing functions of adverbs of manner and ... more than one kind of adverb in a sentence ( adverb of manner, adverb of place and adverb of time), adverb of manner precedes adverb of place and adverb of time So the order of these adverbs is ... following kinds of adverbs: adverbs of time, adverbs of frequency, adverbs of duration, adverbs of place, adverbs of manner, adverbs of degree, linking adverbs, broad negative adverbs and focusing...
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A study on prepositions of direction and some errors made by vietnamese learners
Ngày tải lên :
11/12/2013, 23:53
... Prepositions of Cause 13 Chapter II: Prepositions of direction Prepositions of direction 1.1 What are prepositions of directions 14 1.2 List and meanings Analysis of some examples of preposition of direction ... have no ambition of covering all kinds of preposition and research errors made by learners of all countries in the word, but only prepositions of direction and some errors made by Vietnamese learners ... consisting of a noun preceded and followed by prepositions): by means of (bằng phương tiện), in consequence of (vì thế), on account of (vì, do, bởi), with regard to (liªn quan tới), in front of, in...
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Báo cáo khoa học: Regulation of luteinizing hormone receptor mRNA expression by mevalonate kinase – role of the catalytic center in mRNA recognition potx
Ngày tải lên :
16/03/2014, 06:20
... 9A, the active site of the enzyme is located at the interface of the N- and C-terminal domains of the monomer The adenosine base of ATP is bound at the base of the left-handed b–a–b fold, where ... protein bands were quantified by densitometric scanning followed by analysis using NIH IMAGE 1.61 software, and graphed as a percentage of the control (mean value ± SE) Glu193 in a6 and Asp204 ... overexpression of all the single mutants and wild-type MVK, and Fig 2B shows the overexpression of all the double mutants and wild-type MVK These data indicate that all the mutants and wild-type...
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Báo cáo khoa học: The expression of retinoblastoma and Sp1 is increased by low concentrations of cyclin-dependent kinase inhibitors ppt
Ngày tải lên :
16/03/2014, 23:20
... Rb and Sp1 protein caused by CDK inhibitors in CHO cells The increase in total levels of Rb and Sp1 proteins caused by UCN-01 may be a result of the enhanced transcription and stability of Rb and ... mRNA and protein levels), of both Rb and Sp1 after CDK inhibition by the chemical inhibitors UCN-01, roscovitine and olomoucine, and by the intrinsic inhibitor p21 As DHFR activity is enhanced by ... lCi of [32P]dATP[aP] Ó FEBS 2003 Rb and Sp1 regulation by CDK inhibitors (Eur J Biochem 270) 4811 ´ (3000 CiÆmmol)1; Amersham Iberica), 1.5 U of Taq polymerase (Ecogen) and 500 ng of each of the...
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Báo cáo khoa học: NMR study of cellulose and wheat straw degradation by Ruminococcus albus 20 pdf
Ngày tải lên :
23/03/2014, 07:20
... quantification of fermentation products performed by both 1H NMR (Figs and 2) and enzymatic methods Figure shows an example of the spectra obtained before and after days of culture of R albus 20 ... degradation and metabolism of cellulose and wheat straw by R albus 20 cells growing on these substrates were studied using NMR A kinetic analysis of the polysaccharides degraded and of the sugars ... centrifugation, was freeze-dried and analysed further by 13C-CP MAS NMR The quantification of the 13C signals of the crystalline and amorphous zones obtained on pellets of both cellulose and 13C-labelled wheat...
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Báo cáo khoa học: Presence of membrane ecdysone receptor in the anterior silk gland of the silkworm Bombyx mori pdf
Ngày tải lên :
30/03/2014, 15:20
... to that of 20-hydroxyecdysone A second line of evidence to support the existence of a membrane receptor is that the binding affinity of PonA is less than that of 20E The binding affinity of PonA ... nongenomic action of 20E, and a membrane receptor may mediate the increase in the cAMP level Recently, a membrane progestin receptor has been described as a seven-transmembrane receptor coupling ... binding activity in the membrane fractions was not caused by contamination of nuclear receptors Association and dissociation kinetics The association kinetics of the membrane fractions showed...
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Báo cáo khoa học: Suppression of heat- and polyglutamine-induced cytotoxicity by nonsteroidal anti-inflammatory drugs potx
Ngày tải lên :
30/03/2014, 15:20
... at 37 °C for h and further incubated for h, the cellular levels of Hsp105a and Hsc70 (a constitutive isoform of Hsp70) increased, and the expression of Hsp70 (an inducible isoform of Hsp70) was ... manufacturer’s instructions Results Induction of hsp promoter activity, activation of HSF and accumulation of hsps by IND and NDGA We first examined the effect of IND and NDGA on the hsp105 promoter (Fig ... activation and phosphorylation of HSF in mammalian cells and in synergy with an elevated temperature [21], the activation of HSF by NSAIDs may be in part caused by the inhibition of these enzymes, by...
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báo cáo hóa học:" In vitro generation of cytotoxic and regulatory T cells by fusions of human dendritic cells and hepatocellular carcinoma cells" docx
Ngày tải lên :
18/06/2014, 15:20
... demonstrated by high levels of IFN-γ production and lysis of the CEA- and/ or WT1-positive targets restricted in HLA-A2 and/ or HLA-A24 Interestingly, fusions of immature DCs generated in the presence of ... of antigen-specific CTL and the generation of Treg by fusions of DCs and HCC cells The local tumor-related factors may favor the generation of Treg through the inhibition of DCs maturation; however, ... used for fusion expressed high levels of WT1 and HLA-ABC and low levels of CEA but not HLA-DR, CD80, CD86, and CD83 molecules (Figure 1B, 2A, and 5A) Fusions of DCs to the HCC cells coexpressed...
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báo cáo hóa học:" Concordane of OSTA and lumbar spine BMD by DXA in identifying risk of osteoporosis" pptx
Ngày tải lên :
20/06/2014, 00:20
... of osteoporosis by age and T score cutoffs (T ≤ -2.5 and T ≤ -2.0) of DXA measurement Prevalence Prevalence of osteoporosis by age and T score cutoffs (T ≤ -2.5 and T ≤ -2.0) of DXA measurement ... (n = 92) of moderate risk, and 7.3% (n = 16) of high risk, respectively Figure shows the different cutoffs for LS BMD T score by DXA and the categories of low, moderate, and high risk of osteoporosis ... proposed by Koh LK, which had a sensitivity of 91% and specificity of 45% in identifying women of high risk when compared with final results of femoral neck BMD measurement in Asia women The index of...
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Báo cáo khoa học: "Time of initial detection of fetal and extra-fetal structures by ultrasonographic examination in Miniature Schnauzer bitches" ppsx
Ngày tải lên :
07/08/2014, 23:22
... erofeb noitarutam dna egavaelc citoiem rof ,syad 5-2 ,emit emos eriuqer tub dezilitref eb tonnac sgge detaluvo yltnecer )3( ;emit fo doirep a revo rucco osla nac noitaluvo )2( ;noitaluvo erofeb ... ta nim 01 rof degufirtnec dna ,sebut detaoc-ATDE dellihc ni yletaidemmi decalp ,erutcnupinev cilahpec a hguorht detcelloc erew selpmas doolB ]51[ tnemeganam gnideerb ytilitref a rof detadilav ... QIGOL gnisu demrofrep erew snoitanimaxe cihpargonosartlU ycnebmucer lasrod ni yhpargonosartlu edom-B emit-laer gnisu denimaxe erew sgod eht llA noitirutrap litnu 51 yad morf yliad demrofrep erew snoitanimaxe...
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Báo cáo y học: "Targeted analysis of nucleotide and copy number variation by exon capture in allotetraploid wheat genome" pdf
Ngày tải lên :
09/08/2014, 23:20
... genome Results Specificity and uniformity of alignment A total of 3.5 Mb of target sequence (3,497 cDNAs), represented by 134 kb of 5’ UTR, 2,175 kb of coding and 1,160 kb of 3’ UTR sequences, was ... We then mixed 13 μl of hybridization solution, μl of the library, μl of pre-warmed (65°C) mix of SureSelect Oligo Capture Library, μl of water and μl of RNase block A drop of mineral oil (Sigma, ... better understanding of the global patterns of inter-genomic and intra-species coding sequence divergence and its impact on gene function, large-scale characterization of exonic sequences and gene...
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Báo cáo y học: "Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages" pdf
Ngày tải lên :
11/08/2014, 08:22
... phosphorylation of and degradation of CSM regulates phosphorylation of IRAK IRAK in HEK cells CSM regulates phosphorylation of IRAK and degradation of IκB-α by MDMs and phosphorylation of IRAK in ... like the enhancement of GSH Surface attenuation of TLR4 receptor may be explained by an internalization/shedding of the receptor complex or by changes in the structure of the receptor to cross-link ... 30 and then stimulated by CSM (0.03, 0.06 and 0.12 OD) for h RNA was extracted and mRNA levels of IL-8 were quantified by real-time PCR (A) Results are expressed as copies of IL-8 vs copies of...
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Báo cáo y học: " Phytol-based novel adjuvants in vaccine formulation: 1. assessment of safety and efficacy during stimulation of humoral and cell-mediated immune responses" doc
Ngày tải lên :
11/08/2014, 10:23
... Evaluation of toxicity and safety of phytol adjuvants Adjuvants in general enhance interactions between innate and acquired immunity by mobilizing and activating the former, possibly by promoting ... cytokine milieu generated by these compounds Acknowledgements The authors thank Professors William Brett and Jim Hughes of the Department of Life sciences and Tista Page of 11 (page number not for ... Effects of PHIS-01 and other adjuvants on induction of IgG subclasses The effectiveness of a vaccine formulation depends to a large extent on the type of antibody subclasses induced, and adjuvants...
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Báo cáo y học: "SPLUNC1 regulation in airway epithelial cells: role of toll-like receptor 2 signaling" ppsx
Ngày tải lên :
12/08/2014, 11:23
... expressed and secreted protein in large airway epithelial cells Elucidation of function and regulation of such an abundant protein is critical to understand the role of SPLUNC1 in airway homeostasis and ... manuscript proofreading and editing Page of 10 Author details Department of Medicine, National Jewish Health, and the University of Colorado Denver, Denver, CO, USA 2Department of Immunology, ... 2000, 6:411-415 21 Dziarski R, Gupta D: Role of MD-2 in TLR2- and TLR4 -mediated recognition of Gram-negative and Gram-positive bacteria and activation of chemokine genes J Endotoxin Res 2000, 6:401-405...
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simultaneous removal of arsenic and ammonia from groundwater by phytofiltration with cattails (typha spp.) cultivation tt
Ngày tải lên :
09/01/2015, 08:53
... HANOI UNIVERSITY OF SCIENCE TECHNISCHE UNIVERSITAT DRESDEN NGUYEN TIEN CU SIMULTANEOUS REMOVAL OF ARSENIC AND AMMONIA FROM GROUNDWATER BY PHYTOFILTRATION WITH CATTAILS (TYPHA ... BY PHYTOFILTRATION WITH CATTAILS (TYPHA SPP.) CULTIVATION MASTER THESIS FIELD: WASTE MANAGEMENT AND CONTAMINATED SITE TREATMENT SUPERVISOR: ASSC DR LE VAN CAT HANOI-2008 MỤC LỤC MỤC LỤC DANH MỤC...
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simultaneous removal of arsenic and ammonia from groundwater by phytofiltration with cattails (typha spp.) cultivation
Ngày tải lên :
09/01/2015, 08:53
... contaminants ) 1.4 Phytofiltration Systems 1.4.1 Characteristics of Phytofiltration Systems a/ Phytofiltration: Phytofiltration, the use of plant with extensive root systems and high accumulation ... are perennial and have a high capacity of biomass production and contaminant storage [R.R Brooks, 1998] They are widely distributed on the shorelines of lakes and streams and in wetland ecosystems ... role in phytofiltration systems because the type and textile of soil affect physical, chemical, and biological mechanisms regulating the removal of contaminants from water and soil Sandy soil,...
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Optimization of chitin and chitosan extraction from by product from white leg shrimp (penaeus vannamei) industry in vietnam to improve its quality and efficiency
Ngày tải lên :
15/08/2015, 22:14
... Germay) and has the frequency of 37kHz and RMS of 35W CHAPTER III: RESULTS AND DISCUSSION 3.1 Characteristics of the white leg shrimp by - product The mass average ratio of head and shell of shrimp ... Tyr, Phe, Leu and Val of head and shell part were higher than that of meat one The contents of K and Cu in the shell and head were nearly the same whereas the contents of Na, Ca and Fe were significantly ... temperature of 60oC and native pH DP at the ratio of 1:0 DP at the ratio of 1:1 DP at the ratio of 1:2 Figure 3.3: Effects of treatment time and water ratios used on protein residues and degree of deproteinization...
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