dependence autocorrelations and clusters of extremes
Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): reactivity and structure of metal–thiolate clusters* doc
Ngày tải lên :
16/02/2014, 15:20
... domain After completion of the two Cu(I)4-CysS8-9 clusters, further addition of Cu(I) results in the formation of Cu(I)6-CysS9 clusters and Cu(I)6-CysS11 in the N-terminal and C-terminal domains, ... Thiolate is a soft ligand and therefore shows a preference for soft metals Moreover the structures of metallothioneins are not rigid and hence there is little selectivity concerning the size of the ion ... Cu(I)4,Cu(I)4MT3 and Cu(I)6,Cu(I)6MT3] The determination of a 3D structure seems crucial for understanding the differences between Cu–MT3 and Cu–MT1 ⁄ (structure also not known) and the presence and role of...
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Tài liệu Alcohol-use disorders: diagnosis, assessment and management of harmful drinking and alcohol dependence docx
Ngày tải lên :
21/02/2014, 11:20
... harmful drinkers Alcohol dependence affects 4% of people aged between 16 and 65 in England (6% of men and 2% of women), and over 24% of the English population (33% of men and 16% of women) consume alcohol ... assessment and management of harmful drinking and alcohol dependence in adults and in young people aged 10–17 years This is one of three pieces of NICE guidance addressing alcohol-related problems and ... [TASI]), and cover the following areas: consumption, dependence features and patterns of drinking comorbid substance misuse (consumption and dependence features) and associated problems mental and...
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Báo cáo khoa học: pH dependence, substrate specificity and inhibition of human kynurenine aminotransferase I ppt
Ngày tải lên :
07/03/2014, 16:20
... grateful to Prof Bruce M Christensen, Department of Animal Health and Biomedical Sciences, University of Wisconsin (Madison, WI, USA) and Dr Menico Rizzi (Department of Genetics, University of Pavia, ... based on a standard curve generated using authentic KYNA and the specific activity of the enzyme was expressed as lmolÆmin)1Æmg)1 Effect of buffer and pH on hKAT-I To determine the effect of pH on hKAT-I ... protein standard (lane 3), respectively (B) Spectral changes of hKAT-I following the addition of 10 mM glutamine into hKAT-I solution The concomitant decrease of the 422 nm peak and increase of the...
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Temperature dependence of morphology and diameter of silicon nanowires synthesized by laser ablation
Ngày tải lên :
16/03/2014, 15:09
... mechanism of the silicon nanoparticle chains They proposed that nucleation and growth occurring alternatively resulted in the formation of chains of silicon nanoparticles The formation of the kinks of ... rate of crystal silicon, outer layer of silicon oxide will surround the crystal silicon As a result, the growth of crystal silicon ceased and silicon oxide of outer layer coalesced together and ... nature of a catalyst The nature of a catalyst has a direct influence upon the nucleation temperature and critical nucleus size of the droplets in VLS growth process The addition of Mg and Ge into...
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Báo cáo khoa học: Regulation of the muscle-specific AMP-activated protein kinase a2b2c3 complexes by AMP and implications of the mutations in the c3-subunit for the AMP dependence of the enzyme docx
Ngày tải lên :
30/03/2014, 08:20
... Regulation of AMPK a2b2c3 complexes by AMP K Lindgren et al all of which are required for its activity [8,9] In the mammalian genome, two isoforms of the a-subunit (a1 and a2) and the b-subunit (b1 and ... total activity and the AMP dependence (Fig 1C) We measured the activity of the recombinant AMPK a2b2c3 complexes over a range of AMP concentrations, and calculated the concentration of AMP giving ... with the a2 and b2 isoforms [23] The present study describes bacterial expression of AMPK a2b2c3 trimers, and provides the first characterization of the enzyme kinetic parameters and regulation...
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Báo cáo hóa học: " Formation and reinforcement of clusters composed of C60 molecules" pptx
Ngày tải lên :
21/06/2014, 06:20
... C112 , C 114, C116 and C118 were created (see Figure 5) It is therefore supposed that air and irradiation of UV photons are essential for the reinforcement of clusters composed of C 60 molecules ... which is 6.48 eV, and oxygen atoms were bonded to C60 molecules The order of the diameter of the clusters being 10 nm, it is supposed that C60 molecules located at the surface of the clusters were ... Figure 6) and the clusters somehow reinforced It is inferred that oxidised C60 molecules located at the surface of the clusters may have an important role for the reinforcement of the clusters...
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Báo cáo sinh học: "A comparison between the β-globin gene clusters of domestic sheep (Ovis aries) and Sardinian mouflon" docx
Ngày tải lên :
09/08/2014, 18:22
... fragments of 9.0, 5.5, and 6.6 kb containing the E pair genes of the juvenile, adult, and fetal sets, respectively (Rando et al, 1989) On the other hand, restriction patterns of mouflons with Hb M and ... availability of a mouflon homozygous for the !fBB! allele, we compared the organization of the #-globin clusters of wild Sardinian mouflons and domestic sheep with different Hb phenotypes by means of Southern ... MATERIALS AND METHODS Haemoglobin phenotypes of sheep and wild Sardinian mouflons were determined by means of isoelectric focusing in the pH range 6.7-7.7 and by gel electrophoresis of dissociated...
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Báo cáo y học: "Eukaryotic large nucleo-cytoplasmic DNA viruses: Clusters of orthologous genes and reconstruction of viral genome evolution" pps
Ngày tải lên :
12/08/2014, 04:21
... potential of comparative and evolutionary genomics of the NCLDV increase A pre-requisite of an informative comparative-genomic study of any group of organisms is an accurate delineation of the sets of ... genome of the last common ancestor of the compared genomes [25,26] Accurate identification of clusters of orthologous (COGs) is essential both for functional annotation of uncharacterized genes and ... genomes consisting of genes with different degrees of evolutionary conservation, are in need of and amenable to the same approach Here we describe the construction of clusters of orthologous genes...
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Báo cáo sinh học: " Exact p-value calculation for heterotypic clusters of regulatory motifs and its application in computational annotation of cis-regulatory modules" doc
Ngày tải lên :
12/08/2014, 17:20
... eve2 and random sequences P-value distribution for eve2 and random sequences Distribution of log10 (Pvalue) calculated for the M1 model as a function of cutoff values for PWMs for BICOID and KRUPPEL ... Σi of all texts Ti of length i into classes that and not contain occurrences of Definition A text Ti belongs to class Ci (0; q) iff Length of Ti is i, Values of δ (q, α) function for q ∈ Q and ... 0.633 We took one of the random sequences and compared pvalues calculated for various cutoff values in this random sequence (Figures 3B, 3D) and in the real biological sequence of the eve2 enhancer...
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Báo cáo sinh học: "WordCluster: detecting clusters of DNA words and genomic elements" docx
Ngày tải lên :
12/08/2014, 17:20
... http://www.almob.org/content/6/1/2 clusters of CpGs (CpG islands) using different distance models, 2) detection of clusters of the word CWG (where W = A, T) and 3) detection of clusters of olfactory receptor ... percentage of methylated words (CAG and CTG) inside and outside of the clusters We observed that 26.7% of all CAG/CTG trinucleotides are methylated inside the clusters while 45.3% of them are ... (with JLO), PC and PB carried out the theoretical analysis of word clustering and help with the interpretation of statistical results, GB and AMA retrieve and organize the genome and methylation...
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Báo cáo y học: "Computational identification of developmental enhancers: conservation and function of transcription factor binding-site clusters in Drosophila melanogaster and Drosophila pseudoobscura" ppsx
Ngày tải lên :
14/08/2014, 14:21
... ones, and the span of all scaffolds is 139.3 Mbp.) All of our contigs and scaffolds are freely available by anonymous ftp at [66] Alignment and conservation of pCRMs The extent and pattern of conservation ... key regulators of early development, and the molecular biology and biochemistry of these factors and their target sequences have received a great deal of attention The spatial and temporal embryonic ... evaluation of the efficacy of computational methods for the identification of functional cis-regulatory modules in Drosophila Analysis of the in vivo activity of 36 high-density clusters of predicted...
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Báo cáo y học: "The role of transposable element clusters in genome evolution and loss of synteny in the rice blast fungus Magnaporthe oryzae" pdf
Ngày tải lên :
14/08/2014, 16:21
... the genomes of N crassa and F graminearum by performing BLASTP searches Orthologs could be identified in N crassa for 12.7% of the genes within TE clusters and 59.8% outside of the clusters (Table ... the sequence and measuring repetitive sequence content as the number of TEs per interval, and normalizing for gaps A histogram of these data clearly indicates the presence of three clusters on ... tightly clustered Our analysis of chromosome revealed the interactions The relative rates of evolution between proteins encoded by genes within TE clusters and outside of clusters were compared by...
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Sequencing and characterization of hox gene clusters in japanese lamprey (lethenteron japonicum)
Ngày tải lên :
10/09/2015, 09:32
... D) of elephant shark and human 86 Figure 19 – Alignment of partial exon1 and intron of mouse, zebrafish, and elephant shark HoxB4 and lamprey Hox-α4 genes 87 Figure 20 - VISTA plot of ... 72 Figure 16 – Comparison of four Hox clusters (HOXA, B, C, and D) in human and anole lizard with the lamprey Hox clusters (Hox-α, -β, -γ, and –δ) and the single amphioxus Hox cluster ... timing the 1R and 2R events relative to lamprey and gnathostome divergence Alternatively, I sought clues about the timings of 1R and 2R by analyzing the Hox clusters of lamprey and gnathostomes...
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Chapter 4: Getting Images into and out of Photoshop
Ngày tải lên :
27/08/2012, 14:35
... border to clean up the edges of the selected area of color ߜ Smooth: When you click with the Magic Wand to make a selection of an area of color, you might see all kinds of tiny 1- or 2-pixel areas ... again, and repeat a number of times to create a series of paw prints marching into the distance Figure 8-14: The many faces of transformations The mask-related selection commands At the bottom of ... terms as you read about the various tools and commands with which you make selections Both feathering and anti-aliasing make the edges of your selections softer by using partially transparent or...
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SAP2000® Linear and Nonlinear Static and Dynamic Analysis and Design of Three-Dimensional Structures
Ngày tải lên :
06/09/2012, 15:56
... and all associated documentation are proprietary and copyrighted products Worldwide rights of ownership rest with Computers and Structures, Inc Unlicensed use of the program or reproduction of ... trademark of Microsoft Corporation Adobe and Acrobat are registered trademarks of Adobe Systems Incorporated DISCLAIMER CONSIDERABLE TIME, EFFORT AND EXPENSE HAVE GONE INTO THE DEVELOPMENT AND DOCUMENTATION ... bridge spans 60 feet, and has a width and height of 12 feet each The supports are rollers at one end, and pins at the other The trusses and cross members are to be constructed of 2L4X4’s, while the...
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SAP2000 Integrated Finite Elements Analysis and Design of Structures
Ngày tải lên :
06/09/2012, 15:56
... and all associated documentation are proprietary and copyrighted products Worldwide rights of ownership rest with Computers and Structures, Inc Unlicensed use of the program or reproduction of ... trademark of Microsoft Corporation DISCLAIMER CONSIDERABLE TIME, EFFORT AND EXPENSE HAVE GONE INTO THE DEVELOPMENT AND DOCUMENTATION OF SAP2000 THE PROGRAM HAS BEEN THOROUGHLY TESTED AND USED ... title of the window reads YZ Plane @ X=24 This same title also occurs on the left-hand side of the status bar at the bottom of the SAP2000 window Click the roof level beam on the left side of the...
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The Design and Implementation of a Log-Structured File System
Ngày tải lên :
12/09/2012, 15:05
... areas of cost and capacity rather than performance There are two components of disk performance: transfer bandwidth and access time Although both of these factors are improving, the rate of improvement ... us to understand the effects of random access patterns and locality, both of which can be exploited to reduce the cost of cleaning The simulator models a file system as a fixed number of 4-kbyte ... on disk and in terms of how much of the data written to the log they represent More than 99% of the live data on disk consists of file data blocks and indirect blocks However, about 13% of the...
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The Breadth and Depth of DSP
Ngày tải lên :
13/09/2012, 09:49
... generation and recognition are used to communicate between humans and machines Rather than using your hands and eyes, you use your mouth and ears This is very convenient when your hands and eyes ... very specialized audience State -of- the-art researchers need this kind of detailed mathematics to understand the theoretical implications of the work A basic premise of this book is that most practical ... -Simulation and modeling FIGURE 1-1 DSP has revolutionized many areas in science and engineering A few of these diverse applications are shown here Chapter 1- The Breadth and Depth of DSP in many...
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Cambridge.University.Press.Fearing.Others.The.Nature.and.Treatment.of.Social.Phobia.Mar.2007.pdf
Ngày tải lên :
21/09/2012, 10:54
... Social phobia and disruptive social anxiety are features of the lives of many thousands of people But exactly what is social phobia? What causes it? What is its nature and what kinds of treatments ... key concepts and methods and a substantive body of research, this book aims to answer these questions and clarify social phobia by means of critical discussions and examination of evidence It ... clinicians, and students in clinical and health psychology and psychiatry AR I E L ST R AV Y N S K I is Professor of Clinical Psychology in the Department of Psychology at the University of Montreal...
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Characterization and deactivation of sulfided red mud used as hydrogenation catalyst
Ngày tải lên :
23/09/2012, 14:46
... These samples, and samples of fresh unsulfided and sulfided catalyst, were characterized by nitrogen adsorption and SEM The results of textural characterization by nitrogen adsorption of the catalyst ... related to the intensity of emission of the characteristic Ka line of each element White corresponds to a high concentration of a given element, and black to the absence of this element, while ... Fig SEM-EDX maps of distribution of elements: red mud after h run time The brightness of every pixel of the EDX maps, B, can be quantified on a scale of (black) to (maximum degree of brightness)...
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