delivery of the baby
Báo cáo y học: "Delivery of a baby with severe combined immunodeficiency at 31 weeks gestation following an extreme preterm prelabour spontaneous rupture of the membranes: a case report" pps
... appropriate if the mother is well-informed of the risks for the neonate The conclusions of the ORACLE trials [4,5] indicated that a course of oral erythromycin is the antibiotic of choice in http://www.jmedicalcasereports.com/content/3/1/118 ... being affected with SCID therefore remained at 50% Because of the extremely poor prognosis for the baby, the couple was offered a termination of pregnancy but they declined The pregnancy continued, ... condition and the woman is a carrier of the mutation c.283G>A (W90X) in exon of her IL2RγC gene She was advised of a 50%-risk of any subsequent male offspring being affected by SCID and was thus offered...
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Báo cáo hóa học: " Nanoliposomes for encapsulation and delivery of the potential antitumoral methyl 6-methoxy-3-(4methoxyphenyl)-1H-indole-2-carboxylate" doc
... due to the energy transfer from compound to NBD, the fluorescence intensity of the latter notably increases (Figure 3) The effect is stronger for the membrane of 12 to 14 KDa The percentage of energy ... participated in the draft of the manuscript LAVS was responsible for the antitumoral evaluation of the compound EP supervised the studies of biological activity All authors read and approved the final ... generally leads to the increase of the hydrodynamic diameter that, however, remains close to 100 nm The mean diameter of the Egg-PC/DCP/Ch (7:2:1) liposome is considerably smaller than the others (Table...
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báo cáo khoa học: "Ultrasound microbubble-mediated delivery of the siRNAs targeting MDR1 reduces drug resistance of yolk sac carcinoma L2 cells" doc
... level Page of 11 of MDR1 in L2-RYC cells The highest silencing efficiency was observed in the pooled plasmids group (Figure 1C) Therefore, for the following experiment, we chose to use the pooled ... multiple-drug resistance of L2-RYC cells Thus, the reported approach may represent a novel and new method of combined gene silencing and chemotherapy to combat the drug resistance of yolk sac carcinoma ... The siMDR1-loaded lipid microbubble were obtained with an average diameter of 2.82 ± 0.76 μm, an average concentration of 8.74 × 109/ ml and the average potential of -4.76 ± 0.82 mV (n = 5) The...
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Tài liệu Guidelines for the appointment of General Practitioners with Special Interests in the Delivery of Clinical Services pdf
... a number of factors, including the location of the service and its overall aims In principle ,the main activities of the service will be based around education and improving standards of sexual ... areas The number of sessions should be sufficient to ensure that the GPwSI is able to meet the competencies of the service requirements, the skill being assessed and the level of expertise required ... supervisor/s to confirm the satisfactory fulfilment of the required training experience and the acquisition of the competencies enumerated in this document and others thought necessary by the employing...
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Tài liệu ‘Unheard voices’: listening to Refugees and Asylum seekers in the planning and delivery of mental health service provision in London. pptx
... couples There is a lot of pressure on the couple relationship…Children become more dominant because they learn the language and the mother and the father lose their roles The boundaries and the hierarchies ... form of mental health problem Only one of the interviewees indicated that their problem was not current The nature of these problems is recorded in the table below We have used the words of the ... considerations The FINDINGS section is a key part of the guide as it represents the user perspective, much of it in their own words, and provides the shape and themes for the good practice guide These themes...
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Comparison of the obstetric anesthesia activity index with total delivery numbers as a single denominator of workload demand in Israeli maternity units doc
... Senior Lecturer of Anesthesia and Director of the Obstetric Anesthesia Unit at Shaarei Zedek Medical Center He is the current Chair of the Israel Association of Obstetric Anesthesia His main ... described Methods The Israel Association of Obstetric Anesthesia regularly uses surveys as part of an ongoing assessment of national obstetric anesthesia clinical activity The methodology of these surveys ... all directors of departments of anesthesia or the nominated directors of the obstetric anesthesia units or services in all Israeli hospitals providing labor and delivery services The questionnaires...
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CURRENT TECHNOLOGIES TO INCREASE THE TRANSDERMAL DELIVERY OF DRUGS” pdf
... decontaminated by scrubbing The hair follicles are distributed across the entire skin surface with the exception of the soles of the feet, the palms of the hand and the lips A smooth muscle, the erector pilorum, ... because of the cohesion of the cells of its more superficial layers; a firm and supple skin because of the existence of a dense supportive tissue and of the presence of numerous elastic fibers of ... effect of a surfactant on membrane permeability is the result of its interaction with the membrane and that of the permeant with the micelle Therefore, the concentration of the surfactant is of key...
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Báo cáo khoa học: Recombinant derivatives of the human high-mobility group protein HMGB2 mediate efficient nonviral gene delivery pptx
... complexes in the absence of competitor As shown in Fig 6, in the presence of an amount of free IBBHMGB2186 comparable to the amount of protein in the complex, transfection efciency was only 37% of controls, ... protein To investigate the possible involvement of the endocytic pathway in the internalization of HMGB2186 DNA complexes, cells were also transfected in the presence of the endosomolytic agent ... control The cut-off for eGFP expression was set at the uorescence intensity at which 99.84% of the control cells displayed a lower uorescent signal The bars represent the percentage of eGFP expressing...
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Báo cáo khoa học: The specific delivery of proteins to human liver cells by engineered bio-nanocapsules doc
... protein delivery pattern of topology might clarify the results of previous studies of the topology of the HBsAg protein It is suggested that the C-terminus of the envelope protein protrudes from the ... regions of the L protein The conditioned media were further assessed for the secretion of these different constructs of particles using enzyme immunoassay and fluorescence (Fig 3) When the level of ... of fusion protein at 66.5 kDa The density of the particles obtained from both cell extracts and the conditioned media was equivalent to that of the BNC Whether from the conditioned media or the...
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Báo cáo khoa học: Targeted disruption of one of the importin a family members leads to female functional incompetence in delivery docx
... in the brain, suggesting that the counter-regulation of another importin a isoform may compensate for the lack of a single isoform in vivo in mammals [21] Therefore, to determine whether the ... harm the implanting embryos Furthermore, the number of live pups born to impa5) ⁄ ) females was decreased, probably because of incomplete delivery of some pups On the other hand, as all of the ... wild-type ovaries The graphs represent the impa5) ⁄ ) ⁄ wild-type ratio for the amount of each mRNA The data are expressed as the mean copies of each mRNA per the mRNA levels of the housekeeping...
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the delivery of regenerative medicines and their impact on healthcare - c. prescott, d. polak (crc, 2011) ww
... Werner) The FDA has set up the Office of Combination Products and the Office of Cellular, Tissue, and Cell Therapies Furthermore, and unlike the landscape in a single country such as the U.S., the ... populations of cells (Wang et al 2007) Furthermore, there is currently no clear consensus as to the number of cells needed, the mode/route of their delivery, and the appropriate time during the disease ... of the speed of economic development and the sustained competitive capacity of these states and nations It is the thesis of this chapter that the Intellectual Capital Infrastructure in each of...
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protest of the ukrainian republic to the united states against the delivery of eastern galicia to polish domination. washington d. c., 1919
... submit for the consideration of the Government of the United States the following statement of facts and of the attitude of my Government decision of the Allied and people concerning the and Associated ... before there can be peace "II The settlement of every question, whether of territory, of sovereignty, of economic arrangement, or of political relationship, upon the basis of the free acceptance of ... nothing of century-old strife and the injustice and misery incident thereto principles of natural right It is the opinion of the Government and of the people have the honor to represent, that the...
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báo cáo hóa học:" Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells" docx
... regions of interest were drawn on the basis of the dynamic contrast enhancement pattern of tumor tissue observed following the infusion of Magnevist These data were important for the drawing of accurate ... hypothesized that the major reason for the ineffectiveness of metal-based, lipid-based and biological-based nanoparticles in traversing the BBTB of malignant gliomas is the large size of these ... therapeutics [21], these pores are narrow enough to prevent the effective transvascular passage of most nanoparticles [22-25] If the upper limit of the therapeutically relevant pore size of the BBTB could...
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Báo cáo hóa học: " Efficient data replication for the delivery of highquality video content over P2P VoD advertising networks" pdf
... further assume that the maximum value of R-D slopes for any given packet is therefore an approximation for the importance of that packet to the reconstruction of the video The coding units in the ... scalability of the system in the presence of large and dynamic peers Figure Percentage of requested file received Page 13 of 18 Hence, the proposed approach enhances the scalability of the network, ... assume that the number of peers and the quality of video delivered to the audiencepeers is constrained by the outgoing channel (uplink bandwidth) capacity of sharing peers The problem of free-riding,...
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THE DELIVERY OF NANOPARTICLES doc
... structure The idea was zooming inside the material to find out the novels of discoveries In the last few years, the reality of nanotechnology has changed the dimensions of the world of science ... explored the 3D piece of art of the new tiny world This discovery confirmed that the properties of materials changed as their sizes approaches the nanoscale and as the percentage of atoms at the surface ... about the possibility of the existing of nanostructure in material Prof Feynman actually brought the attention of scientists when he predicted his famous speech: “There’s plenty of room at the...
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Antibody-mediated delivery of IL-10 inhibits the progression of established collagen-induced arthritis docx
... acid linker between the C-terminal of the single-chain Fv fragment and the N-terminal of human IL-10 A His6 tag was appended to the C-terminal of the fusion proteins and the resulting antibody ... for the fusion proteins were 60 μg of L19–IL-2, 15 μg of L19–TNF and 450 μg of L19–IL-10 per mouse The arthritic score was evaluated daily and expressed as the mean ± the standard error of the ... containing the essential elements of the L19–IL-10 or HyHEL10–IL-10 fusion proteins The human IL-10 moiety was fused to the C-terminal of the single-chain Fv antibody fragment by the 15 amino...
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Báo cáo y học: " Substitution of the Rev-response element in an HIV-1-based gene delivery system with that of SIVmac239 allows efficient delivery of Rev M10 into T-lymphocytes" ppsx
... containing construct To the best of our knowledge, our study is the first to evaluate SIV RRE in the context of an HIV-1-based gene delivery system The ability of SIV RRE to render the packaging system ... 'filler', to keep the total amount of DNA added at 1.0 μg The results shown are representative of two independent experiments in another set of transfections, 1.0 μg of pCI-SIV Rev was used The differing ... by dividing the titer of the control vector encoding EGFP alone by the titer of the corresponding vector encoding EGFP and Rev M10 bSIV refers to the molecular clone SIVmac239 using the helper...
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báo cáo khoa học: "Adenovirus-mediated delivery of bFGF small interfering RNA reduces STAT3 phosphorylation and induces the depolarization of mitochondria and apoptosis in glioma cells U251" pdf
... Given the fact that bFGF can activate the STAT3 pathway in many cell types, we investigated in this study whether the antitumor effects of Ad-bFGF-siRNA correlate with the reduced activation of the ... 1B) Interestingly, the expression of pSTAT3 Ser727 moderately decreased at 24 and 48 h and then restored to the control level at 72 h Furthermore, compared with the levels under the control and ... http://www.jeccr.com/content/30/1/80 Page of Figure Ad-bFGF-siRNA reduces the activation of upstream molecules and the expression of downstream molecules of STAT3 in U251 cells (A) Ad-bFGF-siRNA (MOI = 100) reduces the phosphorylation/activation...
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Báo cáo y học: "Rare association between cystic fibrosis, Chiari I malformation, and hydrocephalus in a baby: a case report and review of the literature" potx
... MRI of the brain shows tonsillar herniation to the level of C3 There is effacement of the fourth ventricle and Triventricular hydrocephalus In 1891, Hans Chiari was the first to describe the ... papilledema We hypothesize that the CF precipitated the Chiari malformation although the mechanism is unclear The extensive Chiari malformation then caused obstruction at the fourth ventricle ... next -of- kin for publication of this case report and any accompanying images A copy of the written consent is available for review by the Editor-in-Chief of this journal Acknowledgements The authors...
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Báo cáo y học: "Improving the delivery of care for patients with diabetes through understanding optimised team work and organisation in primary care" ppt
... together explained 31% of the variance in diabetes management These authors, along with others [4,5], identified the need for a better understanding of the relationship between the quality of ... suggest high rates of measurement of clinical and biochemical parameters but lower rates of acting on the results Only 67% of practices achieved the target of 50% of patients having their hemoglobin ... the level of the practice and predictor variables measured at either the level of the practice or the level of the individual The theoretical models will be tested using standard multiple regression...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 sự cần thiết phải đầu tư xây dựng nhà máy từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25