... indicated that the injected GNPs might damage major organs Inthe tissues samples stained with haematoxylin and eosin, the brain, heart, and kidney from to 37 nm GNP-treated mice appeared indistinguishable ... cm-1), falling inthe so-called ‘‘silent region’’ ofthe vibrational spectra ofcellsand tissues As expected, the CARS images ofthe ‘ control ’ did not show appreciable contrast under the non-resonant ... scattering from the GNPs andthe large third-order polarizability ofthe GNPs Enhanced bright spots were observed in neither thecontrol group (a) nor the mice injected with nm GNP (b) Livers obtained...
... through the small intestine (Huang and Adams 2004) The experimental results of Casula and Cutting (2002) suggest that B subtilis germinates inthe jejunum and ileum The adverse conditions inthe ... 634 and 744 were originally obtained from the fresh faeces of healthy piglets The size ofthe inhibitory zone for the six selected isolates against the four indicator pathogens is shown in Table ... analysis for the counts of lactobacilli and E coli according to the methods of Mikkelsen et al (2003) Faeces from the negative controlandthe diet containing spores that performed best during the performance...
... administered during the most active stage of disease [29] The discrepancy between the two studies could be due to a number of factors, including the longevity ofthe injected protein andthe level of free ... between the transgenic mice and littermate controls, the percentage of CD4+CD8- cells within the thymus (3.9 ± 0.4 and 3.6 ± 0.3, respectively), andthe percentage of naïve T cells within the periphery ... measured from urine instead of serum because the absence in urine of natural inhibitors of DNase activity such as G-actin To test if the expression of DNase I from T cellsinthe transgenic mice...
... irradiated the tumor cancer cells simulating the IMRT plans They delivered a total dose of Gy to the cell lines over min, and 20 min, and found that compared with theand group, the survival fraction of ... of group 10.00 control 18 Gy as a single dose Gy× at 60min intervals 2.57 Gy×7 at 10min intervals Gy× at 30min intervals 2.57 Gy×7 at 5min intervals control 18 Gy as a single dose Gy× at 60min ... fractions of 2.57 Gy with interfraction intervals of 10 min, (4) fractions Page ofof Gy with interfraction intervals of 30 min, (5) fractions of 2.57 Gy with interfraction intervals of Assay Tumor dimensions...
... EL4-Gax cells reduced the intensity ofthe slower migrating band and resulted inthe increase ofthe faster migrating band (Fig 4D) When expression ofthe TORC proteins in EL4-Gax cells grown in vitro, ... be involved inthe sustained enhancer binding of CBP inthe absence of Tax Although the amount of pCREB was increased in EL4-Gax cells grown in vivo, no significant difference was observed inthe ... used to analyze the binding of these factors to the U3 region ofthe 5'-LTR Enhancer binding of CREB and pCREB was first examined in EL4-Gax cells either in vivo (b) or under in vitro (a) culture...
... http://www.retrovirology.com/content/1/1/33 tion The data inthe right side of panel A indicate that Cterminal deletions of GagPol extending into the connection domain result in an 85% or greater decrease inthe initiation of reverse ... incorporation of GagPol and tRNALys3into wild-type and mutant HIV-1 The incorporation of GagPol and tRNALys3into wild-type and mutant HIV-1 A Schematic showing the deletions made inthe Pol region of GagPol ... role ofthe RT thumb domain in GagPol in tRNALys3 viral packaging tRNALys3 incorpora- tion into HIV-1 is not affected by deletion oftheIN domain in GagPol, nor by further deletion ofthe RNaseH...
... both sides ofthe Arctic Ocean.33 The disintegration ofthe Soviet Union andthe end ofthe Cold War diminished these threats 32 33 On the Northern Sea Route (NSR) inthe context of vessel-source ... accepting the Court’s jurisdiction inthe matter In justifying these initiatives, Canada relied upon the growing concern for 17 18 19 10 11 12 Ibid., p 71 D Pharand, The Law ofthe Sea ofthe Arctic ... to andcontrolof living and non-living marine resources inthe Arctic remains a US security concern of considerable importance Since the 1950s, the US government has sought to protect these interests...
... implementation of legal instruments for marine environmental protection inthe Southern Ocean Other major issue-areas involved inthe implementation ofthe Protocol include: institutionalisation within the ... areas ofthe Arctic.35 This, then, provided the terms of reference for the PAME working group The scope of its work was defined as the examination ofthe activities/sources of pollution and their ... or the same departmental unit, seems more accentuated inthe ministries of foreign affairs, and less so inthe ministries ofthe environment of these countries The polar marine environment in...
... risks, andthe results thereof Due to the complex nature of certain financial instruments, it is vital that both the entity andthe auditor understand the instruments in which the entity has invested ... to obtain an understanding ofthe entity being audited and its environment, including its internal control, sufficient to identify and assess the risks of material misstatement ofthe financial ... exposed, andthe related risks.19 The auditor’s understanding ofthe instruments may be developed, for example, by understanding the entity’s processes for investing in particular instruments and the...
... perception of disorder and stuffiness.39) The effect of building materials regulating indoor humidity on the indoor environment was studied to identify thein uence on the psycho-physiologic condition of ... use of coal and other fuels for heating and cooking.52) Biological Pollutants Dander, mold, dust, and other organisms carried into by animals and people are biological air pollutants in buildings ... concentration in indoor air is lower in Japan than in other developed countries, the source of lead contamination in dwellings is controversial.122, 123) A paper has indicated that lead in house dust and...
... before the start of each experiment The subsequent incubation with the indicated retinoids was then terminated at the indicated time points by washing with NaCl ⁄ Pi and lysis ofthecells using ... [45] These synthesizing and metabolizing enzymes are involved inthe combined regulation of desirable at-RA levels, and could likewise be involved inthe formation of S-4o9cDH-RA under certain ... between certain combinations of retinoid receptor isoforms CV-1 cells were transfected with plasmids expressing a combination of either RARa and RXRb or RARb and RXRb, together with the reporter...
... residues ofthe IR kinase loop, which help position the PIR–BPS and increase binding affinity [8] Although the interaction of Grb14 with the IR is probably the major determinant ofthe insulin-induced ... partners of Grb14 involved in insulin signaling have been identified: (a) protein kinase Cf interacting protein (ZIP), an adaptor protein that binds to the PIR domain of Grb14 and mediates the assembly ... expression of Grb14 and IR proteins in liver subcellular fractions ofcontroland insulin-injected rats (A) Liver homogenates (H) prepared from five control ()ins) and five insulin-injected (+ins, postinjection)...
... [14,20] Binding of CCE1 results inthe complete unpairing ofthe four base-pairs inthe centre ofthe junctions with a lesser disruption ofthe next base-pairs [19], which is reminiscent ofthe structure ... [38] suggesting that recombination intermediates and enzymes that resolve them could be involved in maintaining the stability and inheritance of mitochondrial genomes in human cells These may have ... Ydc2–GFP resulted in a clear reduction ofthe mtDNA content ofthecells Similar decrease inthe mtDNA content was observed incells expressing the catalytically inactive point mutants andthe truncated...
... with the amino group ofthe main chain at Glu268 The oxygen ofthe main chain at Asp266 was bound to amino groups of main chain of Tyr269 and Ala270 by hydrogen bonds The interactions should maintain ... temperature indicates the stability ofthe structure ofthe protein The difference ofthe increments between the inactive temperature andthe Tm should indicate that the mutations improved the stability ... fill inthe gap between surrounding residues ofthe depression, andthe side chain ofthe mutated residue might restrain the mobility ofthe N-terminal region on the surface by interaction with the...
... first installment ofthe GIVE Challenge, four research teams from the US, the Netherlands, 35 in that the performance of different NLG systems differs considerably Inthe future, we will extend the ... game world and an NLG server at random, and requests the NLG server to spawn a new server instance It then sends the game world to the client andthe server instance and disconnects from them, ready ... disconnect from each other The server instance sends a log of all game events to the Matchmaker, andthe client sends the questionnaire results to the Matchmaker; these then are stored inthe database...
... of this family including UspA itself (Fig 2), and one larger protein consisting of two UspA domains in tandem [17] The small members of this family are proteins of 142–144 amino-acids long; they ... between the amounts of UP12 andthe total amount of protein inthe extracts, a series of samples containing determined amounts ofthe purified UP12 were separated by SDS/PAGE along with the cell ... Department ofthe Weizmann Institute by a single injection of 150 lg ofthe purified protein, followed by two booster shots ofthe same amount of protein at 2-week intervals Serum was collected and used...
... value ofthe indicator i inthe beginning (starting) year ofthe plan, selecting from the poorest target community (maximum value); Vt is the value ofthe indicator i inthe year t; Vp is the prospective ... poverty line Since the headcount index only counts the number of people below a certain poverty line, the poor can become even poorer andthe indicator does not change; Analytically sound: the indicators ... supposed to be applied Often this involves a geographic limitation ofthe scope ofthe indicator For instance, Target of MDG 7, the general indicator of "proportion of land area covered by forests"...
... Engineering in providing services to the government, the public, andthe scientific and engineering communities The Council is administered jointly by both Academies andthe Institute of Medicine ... president ofthe National Academy of Engineering The Institute of Medicine was established in 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions ... by the Governing Board ofthe National Research Council, whose members are drawn from the councils ofthe National Academy of Sciences, the National Academy of Engineering, andthe Institute of...
... Policing web site increases awareness of, and interest in, the police profession, thereby improving police agencies’ ability to attract quality candidates These and other means of communicating innovations, ... command ofthe Policy, Planning and Training Bureau As a captain of police, Riley commanded the 5th Police District, which included the Lower 9th Ward andthe largest concentration of low-income ... andcontrolofthe annual Police Bureau budget, development and dissemination of police directives to the bureau, coordination of training regimens, andthe fostering of communication among the...
... Snf5 activator-binding domains Thein vivo validation ofthe Swi1 and Snf5 activator-binding domains is also of interest in relation to the twostep binding mechanism between Gal4 and Swi1 that ... interactions with other proteins and may be important for the function ofthe increasingly large group of proteins that have been shown to contain intrinsically unstructured regions The intrinsic ... galactose To determine whether the activator-binding domains ofthe SWI ⁄ SNF complex are important for its recruitment to promoters in vivo and to determine whether the Swi1 and Snf5 domains are differentially...