definitions terminologies and computational approaches
Báo cáo y học: "A comprehensive transcript index of the human genome generated using microarrays and computational approaches" pdf
Ngày tải lên :
14/08/2014, 14:21
... hybridization, S Dow for reagent and primer handling, and E Coffey and the Array Production Team for array synthesis We also thank M Krolewski and S Ezekiel for database and programming support Finally, ... Clustering and Alignment Tools (CAT) [44] Input data included all mouse and human RefSeq mRNA sequences, and EST and mRNA sequences from GenBank release 124, masked as described above for repeats and ... homopolymeric run and the number of A residues at the 5' end For example, a probe had to have GC content between 35 and 45% to be in class 1, between 15 and 55% to be in class 2, and between 10 and 60%...
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Molecular and computational approaches to understanding keloid scarring
Ngày tải lên :
10/09/2015, 15:48
... Anandaroop Mukhopadhyay, Dr Masilamani Jeyakumar, Ms Audrey Khoo, Mr Ong Chee Tian, Ms Zhou Yue and Mr Do Dang Vinh from the Wound Healing and Stem Cell Research Group, and to Dr Geoffrey Koh and ... in this thesis, utilizing both molecular and computational approaches, has advanced our understanding by shedding light on some of the important players and key networks in keloid scarring In addition, ... Scientists now want to understand the genes and the role they play in the prevention, diagnosis and treatment of disease.” – Dr Randy Scott, President of Incyte 1.1 Background and motivations for the...
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gene regulation and metabolism post-genomic computational approaches - julio collado-vides
Ngày tải lên :
08/04/2014, 12:45
... book is centered on current computational approaches to metabolism and gene regulation This is an area of computational biology that welcomes new methods, ideas, and approaches with the goal of ... Regulation and Metabolism: Postgenomic Computational Approaches ¨dt, editors, 2002 Julio Collado-Vides and Ralf Hofesta Microarrays for an Integrative Genomics Isaac S Kohane, Alvin Kho, and Atul ... Regulation and Metabolism Postgenomic Computational Approaches ¨ edited by Julio Collado-Vides and Ralf Hofestadt A Bradford Book The MIT Press Cambridge, Massachusetts London, England ( 2002...
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Báo cáo y học: " Computational and statistical approaches to analyzing variants identified by exome sequencing" pdf
Ngày tải lên :
09/08/2014, 23:20
... Ignores structual variants and other forms of genetic variation Assumes causal variant is coding, ignoring regulatory elements and other noncoding variants outside of exon definitions 15,000-20,000 ... cost of adding each additional variable to the model Other approaches, such as logic regression [54] and the method proposed by Han and Pan [55], use data-driven combinations of variants to select ... with one or more rare variants between cases and controls, and the CMC test [57] is based on comparison of non-synonymous rare variants between cases and controls These tests rely on designating...
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IEC 60071 1 insulation co ordination definitions, principles and rules
Ngày tải lên :
25/12/2013, 10:26
... required withstand voltage, accounting for all other differences between the conditions in service and those in the standard withstand test 3.30 standard withstand voltage (U,): The standard value ... associations,onlytwostandardwithstandvoltagesaresufficient define the standard insulation level of the equipment: - to For equipment in range I: a) the standard lightning impulse withstand voltage, and b) the standard ... withstand voltage - For equipment in range Il: a) the standard switching impulse withstand voltage, and b) the standard lightning impulse withstand voltage If technically economically and justified,...
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Tài liệu Báo cáo khoa học: Molecular determinants of ligand specificity in family 11 carbohydrate binding modules – an NMR, X-ray crystallography and computational chemistry approach doc
Ngày tải lên :
18/02/2014, 17:20
... define the ligand specificity in cellulosomal CBMs and the mechanism by which they recognize and select their substrates, we used X-ray crystallography, NMR and computational chemistry approaches ... complex is formed The ligands cellobiose, cellotetraose and cellohexaose were studied Results and Discussion The crystal structure of CtCBM11, the binding cleft and its ligand specificity In a previous ... six-stranded anti-parallel b-sheets that form a convex side (b-strands 1, 3, 4, 6, and 12) and a concave side (b-strands 2, 5, 7, 8, 10 and 11) The concave side is decorated by the side chains of several...
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Tài liệu Báo cáo khoa học: Computational approaches to understand a-conotoxin interactions at neuronal nicotinic receptors doc
Ngày tải lên :
19/02/2014, 12:20
... (–) strand while a narrower one exists above, with contributions from loop C (+), loop B (+), loop E (–), the N-terminus of the b6 (–) and b1 (–) strands and the C-terminus of the b2 (–) strand ... MII, turquoise are indicated ImI and PnIB share W147 and Y193, while PnIA and MII share I186 The small and large shaded regions represent the location of the small and large cavities, respectively ... human [26], rat [23], and a3b2 and a4b4 nAChR neuronal subtype of human [26] 2330 S Dutertre and R J Lewis (Eur J Biochem 271) Ó FEBS 2004 Fig Sequence alignment between AChBP and the N-terminal...
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Tài liệu Hemodynamics – New Diagnostic and Therapeutic Approaches Edited by A. Seda Artis pdf
Ngày tải lên :
19/02/2014, 23:20
... standardized, and should include a minimum wall filter setting of 50 Hz and a Doppler sample volume between and mm (Szatmari et al., 2001) 4 Hemodynamics – New Diagnostic and Therapeutic Approaches ... and blood flow to major organs), CARDFUNC (strength levels of left and right heart), CIRC (pulmonary circulation), REFLEX1 and REFLEX-2 (the activities of sympathetic nerve and vagus nerve, and ... failure and congenital dysplasia Considering RI greater than 0.70 abnormal, the sensitivity and specificity of the RI in differentiating between normal and abnormal kidneys were shown to be 38 and...
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Tài liệu Báo cáo khoa học: "NATURAL VS. PRECISE CONCISE LANGUAGES FOR HUMAN OPERATION OF COMPUTERS: RESEARCH ISSUES AND EXPERIMENTAL APPROACHES" doc
Ngày tải lên :
21/02/2014, 20:20
... stage (feedback on failures and successes), recording the history and current status of the problem solving process, and giving the user comprehensible and powerful co,ands Hansen, W.J., User engineering ... used to classify, control and to repress.") reveal the anger and fear that many people associate with computers The movie producers take their ideas from research projects and the public reacts to ... arc.hair and ponderous when compared with rapid, concise, and precise database manipulation facilities such as Query-by-example or commercial word processing systems It's hard to understand why...
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CULTURAL COMPETENCE IN HEALTH CARE: EMERGING FRAMEWORKS AND PRACTICAL APPROACHES pot
Ngày tải lên :
05/03/2014, 21:20
... “Minority Health and Health Disparities Research and Education Act of 2000,” (S-1880) (November 2000) 16 J P Fortier and Y Shaw-Taylor, “Cultural and Linguistic Competence Standards and Research ... impact of social and cultural factors on health beliefs and behaviors; (2) be equipped with the tools and skills to manage these factors appropriately through training and education; and (3) empower ... ethnically and racially diverse nation, health care systems and providers need to reflect on and respond to patients’ varied perspectives, values, beliefs, and behaviors about health and well-being...
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Đề tài " Classical and modular approaches to exponential Diophantine equations I. Fibonacci and Lucas perfect powers " pdf
Ngày tải lên :
06/03/2014, 08:21
... and (ii) are treated in Sections and 6, respectively Sections and are devoted to step (iii) Sections and 10 are concerned with Steps (iv) and (v) Section 11 deals with steps (vi) and (vii), and ... k ≡ ±1 (mod 6) (b) Fk = U p and Lk = V p for some positive integers U and V The proofs of both Lemmas 5.1 and 5.2 make use of Frey curves and levellowering Here and elsewhere where we make use ... (18) and apply level-lowering Our objective is to give the Lucas analogue of Propositions 7.2 and 7.3 CLASSICAL AND MODULAR APPROACHES 985 Suppose then that (n, y, p) is a solution to (18), and...
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Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx
Ngày tải lên :
07/03/2014, 14:20
... 5.4, 6.3 and 6.6 citrate/phosphate buffer, pH 7.2 sodium phosphate buffer, pH 8.0, 8.3 and 9.0 bicine/HCl buffer and pH 9.0, 9.5 and 10.0 ethanolamine/ HCl buffer [36] Structural analysis and electrostatics ... moves into the ÔupÕ position and interacts with the substrate and Glu144 This rotation of Asp142 is accompanied by removal of a water molecule and adjustments of Tyr10 and Ser93 that seem to compensate ... study are shown in Fig Asp140, Asp142, Glu144 and Asp215 were mutated individually to asparagine and alanine, Tyr10 and Tyr214 were replaced by Phe, and Ser93 was replaced by alanine All clones...
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Báo cáo khoa học: "Mechanical Translation and Computational Linguistics" pptx
Ngày tải lên :
07/03/2014, 18:20
... allow our rough -and- ready everyday understanding of the term "stimulation" to carry us along as we discover the manner in which Quine understands the relation of prompting If, as I stand beside a ... letters and arrows each time they undertake to obey a command In another (game 38), after being trained to follow a written order, the inhabitants are shown the table of letters and arrows once and ... the very reaction described in 37) and 38), and in fact our usual reaction when for instance we hear and obey an order? For, the fact that the training in 38) and 39) preceded the carrying out...
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Coronary Artery Disease – New Insights and Novel Approaches Edited by Angelo Squeri pdf
Ngày tải lên :
08/03/2014, 00:20
... secreted and bound to the hepatocyte Gene Polymorphism and Coronary Heart Disease surface and readily released by heparin It is homologous to LPL and pancreatic lipase and hydrolyzes TGs and phospholipids ... bioactivation and platelet function may be responsible These include CYP2C19 *2, *3 and *17, CYP2C9 *2 and *3, MDR1*2, and functional variants in the genes encoding platelet membrane receptors and intracellular ... 4 Coronary Artery Disease – New Insights and Novel Approaches The coronary artery system consists of two main arteries, the left and right arteries, and their marginal arterial network Anatomically,...
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Báo cáo khoa học: "Evaluating and Combining Approaches to Selectional Preference Acquisition" pptx
Ngày tải lên :
08/03/2014, 21:20
... relation (Re!), verb (Verb), and probability band (Band) The factors Re! and Band had three levels each, and the factor Verb had 10 levels This yielded a total of Re! x Verb x Band = x 10 x = 90 stimuli ... verb and r is an argument slot Li and Abe's algorithm operates on thesaurus-like hierarchies where each leaf node stands for a noun, each internal node stands for the class of nouns below it, and ... co-occurrence frequency, and randomly chose one noun from each band The division ensured that the experimental stimuli represented likely and unlikely verb-argument combinations and enabled us to investigate...
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REGULATING BIOTECHNOLOGY: COMPARING EU AND US APPROACHES BY LEE ANN PATTERSON AND TIM JOSLING
Ngày tải lên :
13/03/2014, 22:08
... category of products, and which does not take into consideration the relative costs and benefits of regulation to industry and the public (Levidow and Tait, 1992 and Tait and Levidow, 1992) A ... (Employment, Social Affairs, and Education), DGVI (Agriculture), DG XI (Environment, Consumer Protection and Nuclear Safety), and DG XII (Science, Research and Development) and became the center of ... hand and Canada and the US on the other This was widely seen as a test case for the new SPS Agreement Though the panel and the subsequent appellate body reports did indeed clarify the scope and...
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HEMODYNAMICS – NEW DIAGNOSTIC AND THERAPEUTIC APPROACHES potx
Ngày tải lên :
14/03/2014, 10:20
... standardized, and should include a minimum wall filter setting of 50 Hz and a Doppler sample volume between and mm (Szatmari et al., 2001) 4 Hemodynamics – New Diagnostic and Therapeutic Approaches ... and blood flow to major organs), CARDFUNC (strength levels of left and right heart), CIRC (pulmonary circulation), REFLEX1 and REFLEX-2 (the activities of sympathetic nerve and vagus nerve, and ... HEMODYNAMICS – NEW DIAGNOSTIC AND THERAPEUTIC APPROACHES Edited by A Seda Artis Hemodynamics – New Diagnostic and Therapeutic Approaches Edited by A Seda Artis Published by InTech...
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Báo cáo khoa học: "Computational Approaches to Sentence Completion" docx
Ngày tải lên :
16/03/2014, 19:20
... research groups including Terra and Clarke (2003) and Pado and Lapata (2007) These questions are similar to the SemEval task, but in addition to the original word and the sentence context, the ... Jarmasz and Szpakowicz (2003) used a sophisticated thesaurusbased method and achieved state-of-the art performance, which is 82% Other work on standardized tests includes the synonym and antonym ... matrices u and v and nonlinear functions f () and g() (Mikolov et al., 2011b): x(t) = [w(t)T s(t − 1)T ]T sj (t) = f ( xi (t)uji ) i yk (t) = g( sj (t)vkj ) j with f () being a sigmoid and g() a...
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Báo cáo khoa học: "a system for tutoring and computational linguistics experimentation" pptx
Ngày tải lên :
17/03/2014, 00:20
... the effectiveness of different approaches to tutoring, and the differences between human-human and human-computer tutoring Previous comparisons of human-human and humancomputer dialogue were ... policies Conclusions and Future Work Acknowledgments The B EETLE II system we present was built to serve as a platform for research in computational linguistics and tutoring, and can be used for ... Marques-Pita, Colin Matheson, and Johanna D Moore 2007 The Beetle and BeeDiff tutoring systems In Proceedings of SLaTE’07 (Speech and Language Technology in Education) Staffan Larsson and David Traum 2000...
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Peripheral Neuropathy – Advances in Diagnostic and Therapeutic Approaches Edited by Ghazala Hayat pot
Ngày tải lên :
17/03/2014, 02:20
... muscle wasting in the hands Symptoms in the advanced cases may include muscle waste in the hands and fore arms, neck and shoulder, vocal cords, which leads to scoliosis and malfunction in chewing, ... muscle tissue and loss of touch sensation of limb, predominantly in the feet and legs, foot drop, and hammer toes The most frequent initial symptoms include foot drop, claw toe, and muscle wasting ... peripheral and central nervous system diseases, and developed new therapeutic approaches towards these diseases Peripheral neuropathy is a common disorder seen by many specialists and can pose...
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