... collection ofoperatingsystem primitives defined such that a programmer has the option of
choosing to use either shared memory or message-based communication as the basis for the implementation of a
multithreaded ... may be located on either ofthe clients’ hosts, or on yet
another host.
In the second frame, each client takes a read fault on the same page ofthe shared memory region. The same page
may be ... tasks.
Many other operating systems have met with this problem. Often these systems solve the problem by using inside
knowledge ofthe algorithms used to manage secondary storage. Unfortunately, the Mach...
... and Professor of Economics at the
Wharton School ofthe University of Pennsylvania
Thorsten Beck Professor of Economics and Chairman ofthe European Banking
Center, Tilburg University, Netherlands
Charles ... transmission
of information in the price, and greater effi-
ciency ofthe market. In the bond market, the
most commonly used variable is the tightness
of the bid-ask spread (with the U.S. and ... development and theroleof
the state in finance.
Despite the crisis experience, 90 percent ofthe
country officials and experts surveyed in the poll
perceive that positive effects of finance (in...
... must still be determined whether
its absence in the V79-G18 mutant is the result ofthe missing
ESSS subunit alone, or whether the absence of ESSS causes
the f ailure of other integral membrane subunits ... as a nother identification of
the complex at the position o f the histochemical stain in the
left panel. Antisera against the SDHC subunit of complex II
and against the Rieske protein of complex ... and the effect of
the absence of intact complex I, but the results are too
preliminary in this regard.
Heterologous expression ofthe ESSS-HA subunit
The localization ofthe ESSS subunit in the...
... ducts is of
considerable significance in the pathology of a number
of diseases including cystic fibrosis and cancer.
Equally important is the fate ofthe cytoplasmic tail
of the mucins once the extracellular ... required for efficient
cleavage [11].
The solution structure ofthe SEA domain of the
mouse homologue of MUC16 (which in the human
encodes the core protein ofthe ovarian cancer antigen
CA125) was ... contained in a surface-exposed loop. To further
investigate theroleofthe SEA domain in cleavage of
membrane-tethered mucins we carried out site-directed
mutagenesis ofthe FRPG ⁄ SVVV site and...
... binding of
GTP to the allosteric site promotes coordination of the
phosphorylation of UTP and hydrolysis of glutamine for
optimal efficiency in CTP synthesis rather than just acting to
increase the ... ATP-cS. On the basis of these results, ATP-cS
was chosen as a binding analog of ATP. CTP synthesis
requires the presence of both the nucleotide substrates ATP
and UTP. When phosphorylation of UTP ... locks the enzyme in the active form for CTP synthesis and
thereby stimulates the k
cat
of the reaction. Since GTP actually will
activate the uncoupled glutaminase reaction the structure of the
monomer...
... sense of group identity, in the eyes of its
members and those outside the group.
What is theroleofthe facilitator?
The roleofthe facilitator is to make it easier for
groups to work together ... 1. TheRoleofthe Facilitator – page 6
What is theroleofthe facilitator?
How do facilitators help groups achieve their goals?
They do it by
• Clarifying and reinforcing the purpose ofthe ... Facilitation - 1. TheRoleofthe Facilitator – page 11
Group dynamics
Facilitators need to be aware both ofthe
communication styles ofthe individuals who
make up the group, and ofthe way the group...
... examine
the dynamics of tobacco-related media
interventions at each of these levels, within
a systemic framework.
The relationships among these levels and
stakeholders on either side ofthe tobacco ... provide the advantage of
internal validity and are helpful in confirming
causal relationships. These experiments,
however, are often limited in terms ofthe
rather forced nature of exposure, ... nature of
several tobacco promotional campaigns;
(3) the unavoidable exposure of youth to
these campaigns; (4) theroleof tobacco
advertising and promotion in increasing
tobacco use in the...
... For the purposes of this analysis however we have
chosen the boundaries ofthe situational analysis to reflect those ofthe ‘political’ region of South East
Queensland (see Figure 1b). The ...
health ofthe aquatic ecosystem. There are several measures ofthe level of nitrogen present in a water body,
these include TKN, ammonia, nitrate and nitrite concentrations. The quantity of phosphorus ... et al 2008).
One ofthe key positive unintended outcomes ofthe EHMP was the building of momentum leading
to the establishment ofthe Partnership. The EHMP began in 1999, and the Partnership...
... 0.8%. A possible
interpretation ofthe data suggests that the indicated
basic region of ic3 ofthe D
2
receptor and acidic region
of the C-tail ofthe D
1
receptor might be involved in
the interactions ... localization of these proteins in the cell rather than
from the possible roleofthe D
2
R basic domain in the mechanism of
D
1
–D
2
receptor heterodimerization. However, we find that the acidic
epitope ... efficiency in the trafficking ofthe wild-type D
2
receptor [61].
The construction of genetic variants ofthe studied
dopamine receptors, which were supposed to prove the
contribution ofthe indicated...
... sequence contacts the
c-phosphate ofthe bound nucleotide across the
dimer [15] and the aromatic residue ofthe A-loop
stacks against the adenine moiety of bound
nucleotide and provides further stabilization ... cleavage ofthe c-phosphate does occur in the
NBD with the mutation at the IC [36,38,39]. More-
over, these and other studies suggest that the IC
residues are involved in the formation ofthe NBD
dimer, ... activates the attacking
water molecule that cleaves the terminal phosphate of
bound ATP. In the latter model, the IC is part of a
catalytic dyad, along with the histidine residue of the
H-loop, and positions...
... has
been proposed that metabolic channeling of (E)-cin-
namic acid requires the close association of specific
forms of PAL with C4H on microsomal membranes
[63].
The site of phosphorylation of French ... study
the behavior ofthe Tyr110-loop in PAL in more
detail.
Results and discussion
Modeling the active conformation of the
essential Tyr110-loop of parsley PAL
Because ofthe uncertainty ofthe ... the biosynthesis ofthe photoactive yellow protein
chromophore of these bacteria.
The two recently discovered aminomutases, the phe-
nylalanine 2,3-aminomutase (PAM) involved in taxol
biosynthesis...
... family. One ofthe women told that she had been at the offices of
the company and an officer showed her the papers related to the purchase of lands ofthe family.
According to him, they had just ... from the existence of swamps.
The Pampa ofthe South of Brazil, in the State of Rio Grande do Sul (RS) borders another two
countries ofthe Pampa: Uruguay and Argentina.
Due to a number of ... meet the needs ofthe communities. On the contrary,
they were designed on the basis of an agro-export model geared to the countries ofthe North – and
the European Union specifically in the...
... upstream
of the GAF domain are the potential ligands of the
Fe-S cluster. Consequently, the binding ofthe ATP
analog and the subsequent rearrangement ofthe inter-
domain interaction affects the ... electronic condition of
the Fe-S cluster through the protein scaffold, resulting
in an alteration ofthe signal rhombicity ofthe EPR
spectrum. The divergence ofthe g-value from that of
the whole cell ... level ofthe lacZ gene immediately after the
addition of o-phen to minimize the effect ofthe growth
inhibition by o-phen on the transcriptional activity of
VnfA. Figure 5 shows the time course of...
...
discrepancies within the nursing profession with regard to specialist/
advanced nursing titles, differing roles and the educational needs of
these nurses.
In the United Kingdom, the idea of advanced ... ongoing professional development, rather than a
requirement of their job description.
The implementation within the NHS ofthe Agenda for Change in
2005 aimed to evaluate nursing roles based ... participation in the research process. If the
aim of clinical nurse specialists is to enhance patient care, then research
must be part oftherole (Armstrong 1999). It will involve their awareness
of current...
... thereby revealing the close network
of interactions that hold the terminal glucose ofthe b-
glucan substrate in the )1 subsite at the bottom of the
active site pocket [20]. The entrance to the ... 3N9K
a
BGC1 is the glucose residue from the nonreducing end of laminaripentose (L5) bound to the exterior ofthe protein.
b
BGC2 is the weakly
bound glucose residue of L5 bound in the Phe-Phe clamp.
c
L3-1 ... implemented
to help explain their importance to the specificity and
catalytic efficiency ofthe enzyme.
The roleofthe Phe-Phe entranceway
The fortuitous discovery of an unreacted molecule of
the mechanism-based...