decision to know and decision to act

A knowledge based approach to active decision support

Ngày tải lên : 16/09/2015, 14:04

... the alternatives and send this information to the tools Then the tools induce a solution according to decision makers’ requirements and send it back to decision makers After a decision is made, ... monitoring the decision making process of the user and detecting inconsistencies and problems; understanding and inferring users context, goals and intentions and automatically scheduling and ... and break-even analysis model; and (c) providing tools to enhance the user's ability to balance strategic (global and long-term) and opportunistic (local and short term) thinking The active decision...

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Development of the Quantitative PCR Method for Candidatus ‘Accumulibacter phosphatis’ and Its Application to Activated Sludge

Ngày tải lên : 05/09/2013, 09:38

... Most eubacteria Most eubacteria, archaebacteria Candidatus ‘Accumulibacter phosphatis’ Candidatus ‘Accumulibacter phosphatis’ Candidatus ‘Accumulibacter phosphatis’ Candidatus ‘Accumulibacter phosphatis’ ... PAO651 and PAO846) and an FITC-labeled EUBMIX (EUB338, EUB338 II and EUB338 III) probe (Table 1) The targets of PAOMIX and EUBMIX probe are Candidatus ‘Accumulibacter phosphatis and most eubacteria, ... extracted from activated sludge was related to those of Candidatus ‘Accumulibacter phosphatis’ Standard curves were constructed from 1.0×103 to 1.0×107 copies of the DNA quantification standard...

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An investigation into learning and teaching english vocabulary at cua lo hihg school and some suggested activities to help students learn better

Ngày tải lên : 18/12/2013, 10:08

... In fact, grammatical knowledge allows us to generate sentences At the same time, though, we must have something to say; we must have meanings that we wish to express, and we need to have store ... sounds and meanings interlock to allow us to communicate with one another, and it is a word that we arrange together to make sentences, conversations and discourse of all kinds 1.2 Understanding ... their memory: active and passive vocabulary The former refers to vocabulary that students have been learnt or taught and which they are expected to be able to use while the latter refers to words...

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Tài liệu iPhone and iPad in Action: Introduction to SDK Development docx

Ngày tải lên : 12/02/2014, 20:20

... methods and properties An introduction to actions 99 The UIControl object 99 Control events and actions Using addTarget:action:forControlEvents: 101 ■ 6.5 Adding a button to an application Other action ... technical questions, and receive help from the authors and from other users To access the forum and subscribe to it, point your web browser to http://www.manning com/iPhoneandiPadinAction The Author ... wrong way to hold the device Never before has any device supported such a feature 1.5 Understanding iPhone and iPad touch interaction The iPhone and iPad use a multitouch-capable capacitive touchscreen...

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Tài liệu Báo cáo khoa học: Regulation of connective tissue growth factor (CTGF/CCN2) gene transcription and mRNA stability in smooth muscle cells Involvement of RhoA GTPase and p38 MAP kinase and sensitivity to actin dynamics docx

Ngày tải lên : 19/02/2014, 16:20

... of ﬁlamentous (F-actin) content compared with free globular actin (G-actin) content was performed using the F-actin/G-actin in vivo assay kit from Cytoskeleton according to the manufacturer’s ... the actin cytoskeleton architecture orchestrated by RhoA regulates the CTGF/CCN2 gene by acting as a catalytic surface and/ or protein cofactor for these transcription factors [39] The exact mechanism ... (2000) Factor VIIa and thrombin induce the expression of Cyr61 and connective tissue growth factor, extracellular matrix signaling proteins that could act as possible downstream mediators in factor...

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Tài liệu Báo cáo Y học: Binding of gelsolin domain 2 to actin An actin interface distinct from that of gelsolin domain 1 and from ADF/coﬁlin pptx

Ngày tải lên : 22/02/2014, 07:20

... ð1Þ where C and E are total concentrations of peptide and actin, respectively, and X is the relative fluorescence change A/Amax (corresponding to the fraction of peptide bound to actin) A plot ... 159–193 and cofilin to various parts of actin and whole actin in the F- and G-form by similar methods Note that no Kd value is given for cofilin binding to F-actin as the co-operativity of the interactions ... itself has also been shown to bind F-actin [34], with a Kd of mM Residues 198–227 of human gelsolin bind actin, cross-link to F-actin and compete with S2–3 for binding to F-actin [33] A deletion...

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Báo cáo khoa học: Induction of PPARb and prostacyclin (PGI2) synthesis by Raf signaling: failure of PGI2 to activate PPARb potx

Ngày tải lên : 07/03/2014, 12:20

... increase in the synthesis and release of PGE2 and PGI2 which was mainly due to a strong transcriptional activation of the Cox-2 gene (and to a lesser extent of PGIS and mPGES-1) Under the same ... with Taq DNA polymerase to add 3¢ oligo(A) overhangs and cloned into pCRIITOPO (Invitrogen) Finally the LexA-PPARb-LBD fragment was cut with BamHI and HindIII and subcloned into pcDNA3.1zeo (Invitrogen) ... MS equipped with a Varian (Palo Alto, CA, USA) 3400 gas chromatograph and a CTC A200S autosampler was used [39] Acknowledgements We are grateful to Margitta Alt and Bernhard Watzer for excellent...

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A Manual for Integrating Gender Into Reproductive Health and HIV Programs: FROM COMMITMENT TO ACTION pptx

Ngày tải lên : 14/03/2014, 15:20

... used to guide program decisions throughout the life of a project The Manual is organized to be user-friendly Some users may wish to refer to Chapters and to understand the guiding principles and ... knowledge, and power to make informed RH/HIV/AIDS decisions Empowerment is “the sustained ability of individuals and organizations to freely, knowledgeably, and autonomously decide how best to serve ... able to assess and formulate new visions and approaches to RH and gender relations that allow individuals to make independent and informed choices and changes in their lives (see Steps 1, 3, and...

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Báo cáo khoa học: Intrinsic local disorder and a network of charge–charge interactions are key to actinoporin membrane disruption and cytotoxicity ppt

Ngày tải lên : 14/03/2014, 23:20

... proportional to the reported B-factors (pdb:1gwy) The secondary structure elements and the side chains of R29 and Y111 are shown The ﬁgure was created with MOLMOL [29] the Y111N In fact, the lytic activity ... present higher R2 values with respect to the mean These correspond to residues 82–84 and 104 in the membrane interaction face and segments 140–147 and 159–163 towards the end of the protein sequence ... [26] and incorporated into the structure calculation protocol Initially, 100 conformers were generated that were forced to satisfy the experimental data during a standard automatic cyana protocol...

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Báo cáo khoa học: Cas utilizes Nck2 to activate Cdc42 and regulate cell polarization during cell migration in response to wound healing docx

Ngày tải lên : 23/03/2014, 03:20

... cells, and cells were lysed at the indicated time points to detect total Cdc42 and active, GTP bound, Cdc42 (C) Forty scratches were made and, h later, cells were lysed to detect total and active ... protein to regulate Cdc42 activation [36] In that case, PAK1 associates with both Gbc and PAK-interacting guanine nucleotide exchange factor a (aPIX) to activate Cdc42 in response to chemoattractants ... were performed to measure Cdc42 activity in the absence of Nck2 and the graph indicates the relative activity of Cdc42 (mean ± SD) biological activities, including actin cytoskeleton reorganization...

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barriers to asset recovery an analysis of the key barriers and recommendations for action

Ngày tải lên : 26/03/2014, 14:08

... instruments and standards such as UNCAC, UNTOC, and the FATF recommendations, but practical implementation and operational changes are required to give full effect in practice to these standards ... refers to the demonstrated and credible intent of political actors, civil servants, and organs of the state to combat corruption and recover and repatriate stolen assets Although difficult to define ... strategy is necessary to define goals and targets, to identify all available tools (laws and regulations as well as processes), to mobilize the needed expertise and resources, and to make stakeholders...

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A Manual for Integrating Gender Into Reproductive Health and HIV Programs: From Commitment to ACtion (2nd edition) ppt

Ngày tải lên : 28/03/2014, 14:20

... implementation, and monitoring and evaluation of USAID program and policy support activities; n Include gender indicators and sex-disaggregated data collection into the program monitoring and evaluation ... continuum, acknowledge the role of gender norms and inequities and seek to develop actions that adjust to and often compensate for them While such projects not actively seek to change the norms and inequities, ... active legislator, and to enter into legal contracts This domain refers to how people of different genders are regarded and treated by both the customary and formal legal codes and judicial systems...

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Báo cáo hóa học: " Hantaviruses and TNF-alpha act synergistically to induce ERK1/2 inactivation in Vero E6 cells" docx

Ngày tải lên : 20/06/2014, 01:20

... Gardner AM, Johnson GL: Fibroblast growth factor-2 suppression of tumor necrosis factor-α mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase J Biol Chem 1996, ... we studied the activation of extracellularsignal regulated kinases and (collectively referred to as ERK1/2), a well-known group of mitogen-activated kinases (MAPKs) and regulators of cell survival ... by ERK1/2 inactivation and confirm that ERK1/2 activity is an important factor for maintaining cell viability To verify that ERK1/2 down-regulation was mediated by virus replication and not merely...

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Báo cáo hóa học: " Converting Layered Zinc Acetate Nanobelts to One-dimensional Structured ZnO Nanoparticle Aggregates and their Photocatalytic Activity" docx

Ngày tải lên : 22/06/2014, 01:20

... precursor in air ZnO can be used as photocatalytical semiconductor due to a band gap, which can be activated by UV-irradiation [15] Under UV-irradiation, holes and electrons are yielded which possess ... measured to give information of the CH3COO group and OH group within the interlayer The broad absorption band at 3,420 cm-1 can be assigned to the OH group and water The two weak peaks at 2,920 and ... mode The bands at 1,340 and 1,010 cm-1 can be assigned to the deformation and rocking modes of the CH3 group [16–19] The difference between antisymmetric COO- stretching vibration band and symmetric...

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how to act like a ceo 10 rules for getting to the top and staying there pot

Ngày tải lên : 28/06/2014, 21:20

... loving and caring and mentors interdependence To have good friends to share our lives with To always keep learning To be responsible and accountable to me first, and society second And finally, to ... what they know into simple, workable advice To act like the best CEOs act out there, I condensed what they have to say into 10 CEO rules to help you on your trip to the top You—tomorrow’s CEOs—should ... completing this project goes to several people My husband, Rodney Sweeney, and to “Scooter” My parents, Fred and Teresa Benton My agent, Mike Cohn, and editor, Mary Glenn And some special friends:...

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Báo cáo khoa học: "The response of dehydrated Douglas fir (Pseudotsuga menziesii) pollen to three in vitro viability assays and their relationship to actual fertility" doc

Ngày tải lên : 08/08/2014, 23:22

... contribution (El-Kassaby and Ritland, 1986b), improve seed yields (Webber, 1987) and reduce the negative impact of selfing and contamination (El-Kassaby and Ritland, 1986b; Wheeler and Jech, 1986b) However, ... (Smith and Adams, 1983; El-Kassaby and Ritland, 1986a; Wheeler and Jech, least, comparable fertility potential to set Pollen management procedures for handling Douglas fir pollen have been tested and, ... this study are to optimize the response of viability assays (respiration, leachate conductivity and germination) using stored Douglas fir pollen and to relate these responses to actual seed set...

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Báo cáo y học: "Impaired vascular responses to parasympathetic nerve stimulation and muscarinic receptor activation in the submandibular gland in nonobese diabetic mice." ppt

Ngày tải lên : 09/08/2014, 01:22

... Inflammatory cytokines and chemokines can activate vascular cells and are suggested to be involved in atherogenesis [28] In autoimmune diseases, vascular cells can actively contribute to the inflammatory ... of vasoactive intestinal peptide-immunoreactive nerve fibres in submandibular glands Light microscopic view of vasoactive intestinal glands peptide (VIP)-immunoreactive (IR) fibres in submandibular ... labial salivary gland tissue from patients with SS [13] Nitric oxide (NO) signalling is activated through muscarinic receptors in the salivary glands [14,15], and NO synthase activity and expression...

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Báo cáo y học: "Retinoid X receptor and peroxisome proliferator-activated receptor-gamma agonists cooperate to inhibit matrix metalloproteinase gene expression" potx

Ngày tải lên : 09/08/2014, 13:22

... The peroxisome proliferatoractivated receptors: ligands and activators Ann N Y Acad Sci 1996, 804:266-275 Mangelsdorf DJ, Evans RM: The RXR heterodimers and orphan receptors Cell 1995, 83:841-850 ... enzymatic activity of histone deacetylases (HDACs) and histone acetyltransferases (HATs) [12] HDAC activity results in a decrease in histone acetylation and a subsequent decrease in transcriptional activity, ... NHRs, including retinoic acid receptors, thyroid receptor, vitamin D receptor, PPARs, liver X receptors (LXRs), and farnesoid X receptor (FXR) [22], the ligand LG268 activates only a subset of the...

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how to act like a ceo 10 rules for getting to the top and staying there phần 1 pot

Ngày tải lên : 10/08/2014, 07:21

... what they know into simple, workable advice To act like the best CEOs act out there, I condensed what they have to say into 10 CEO rules to help you on your trip to the top You—tomorrow’s CEOs—should ... completing this project goes to several people My husband, Rodney Sweeney, and to “Scooter” My parents, Fred and Teresa Benton My agent, Mike Cohn, and editor, Mary Glenn And some special friends: ... 122 HOW TO ACT LIKE A CEO The Technical Expert(s) Public or Private Companies 124 126 Act Like a CEO Even When You Don’t Feel Like It To Act Like a CEO Is to Perform—Both in Action and Acting...

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