cushing apos s syndrome pathophysiology diagnosis and treatment contemporary endocrinology
Báo cáo y học: "Primary prevention of Down’s syndrome"
... hypotheses The cause of DS has been sought in disturbances during stages of oogenesis, including the period of meiotic arrest of the oocyte [51] This has generated several hypotheses One possibility ... Arbuzova S Epidemiology of aneuploidy In: Evans MI, ed Prenatal diagnosis: genetics, reproductive risks, testing, and management York, PA, USA: Techbooks 2005 Hassold T, Sherman S Down syndrome: ... Arbuzova S Multianalyte Maternal Serum Screening for Chromosomal Defects In: Milunsky A, ed Genetic Disorders and the Fetus: Diagnosis, Prevention and Treatment - 5th edition USA :Johns Hopkins University...
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Handbook of Tourette''''s Syndrome and Related Tic and Behavioral Disorders, Second Edition doc
... blepharospasm or Meige Motor and Vocal Tics syndrome should be considered voluntary because they are used as tricks to suppress the dystonic movements Tics Status or Status Tics Rarely, motor and ... Belmont, Massachusetts, U .S. A Loren Gianini Massachusetts General Hospital, Cambridge, Massachusetts, U .S. A Christopher G Goetz Rush University, Chicago, Illinois, U .S. A Stacy Horn Rush University, ... dystonia) is triggered by sudden movement or startle, lasts seconds to a few minutes, and is suppressed with anticonvulsant therapy Paroxysmal dystonic choreoathetosis is induced by stress, prolonged...
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Cushing''''s Syndrome pdf
... suspicion about Cushing' s Syndrome Ectopic Cushing' s Syndrome tends to present with less impressive classic features, but more dramatic hypertension and loss of potassium, sometimes in the setting of ... steroid medication is extremely common because of the widespread use of these medicines in treating many illnesses Spontaneous Cushing' s Syndrome and Cushing' s disease can occur in children and ... Both are also to times more common in women than men WHAT ARE THE SYMPTOMS AND SIGNS OF CUSHING' S SYNDROME? Cortisol excess produces significant and serious change in the appearance and health...
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HOW IS CUSHING''''S SYNDROME DIAGNOSES? pptx
... inflammatory bowel disease Sometimes physicians are able to decrease steroid doses by using other drugs in the treatment of these diseases All of the types of spontaneous Cushing' s Syndrome should be carefully ... and frustrated by the slow improvements in physical changes and the combination of Cushing' s and adrenal insufficiency signs and symptoms (dizziness, weakness, nausea, loss of appetite) as replacement ... signs and symptoms mentioned earlier Regular visits to a physician for examinations, blood tests, and treatments of infections and complications will be necessary and are often viewed as a sever...
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HỘI CHỨNG CUSHING (Cushing’s syndrome) ppt
... nghiệm cortisol tự do, 17hydroxycorticosteroid đo mẫu cortisol máu lúc 8h Ngày thứ cho bệnh nhân uống dexamethason 2mg/6h S có khả xảy ra: Nếu bệnh Cushing cortisol máu 17hydroxycorticosteroid ... loãng xương thường thấy cột s ng, xương s ờn xương dài, gãy xương bệnh lý xương s ng xương s ờn, xẹp đốt s ng phát nhờ chụp X quang - Tiêu hoá: tăng tiết HCl pepsin dày nên thường hay bị loét dày, ... thận, giảm bình thường có u lành (adenoma), cường s n vỏ thượng thận bình thường tăng + Các xét nghiệm để chẩn đoán phân biệt hội chứng Cushing bệnh Cushing (do cường thùy trước tuyến yên) - Định...
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Báo cáo y học: "Genetic aspects of Sjögren’s syndrome" pptx
... Bombardieri S, Jonsson R, Moutsopoulos HM, Alexander EL, Carsons SE, Daniels TE, Fox PC, Fox RI, Kassan SS, Pillemer SR, Talal N, Weisman MH: Classification criteria for Sjögren s syndrome: a revised ... M, Skarstein K, Bolstad AI, Johannessen AC, Jonsson R: Fas-induced apoptosis is a rare event in Sjögren s syndrome Lab Invest 2001, 81:95-105 Ohlsson M, Jonsson R, Brokstad K: Subcellular redistribution ... expression This makes the genetics behind these diseases more complicated than those of diseases with a simple Mendelian character Sjögren s syndrome is major histocompatility complex associated...
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Báo cáo y học: "α Anti-α-fodrin antibodies do not add much to the diagnosis of Sjögren’s syndrome" pot
... against La-antigen; hLFS, lymphocytic focus score ≥ 1.0 in sublabial minor salivary glands biopsy DM, dermatomyositis; Pt, patient; SSc, systemic sclerosis; SLE, systemic lupus erythematosus aIgA, ... Bombardieri S, Jonsson R, Moutsopoulos HM, Alexander EL, Carsons SE, Daniels TE, Fox PC, Fox RI, Kassan SS, Pillemer SR, Talal N, Weisman MH: Classification criteria for Sjogren s syndrome: a revised ... Arthritis Research & Therapy Vol No Zandbelt et al bodies is limited (besides being found in SjS, they are also found in systemic lupus erythematosus [SLE]), and the sensitivities of anti-Ro and...
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báo cáo khoa học: "Scintigraphic features of Morquio’s syndrome: a case report" pptx
... 46-year-old Caucasian man with Morquio s syndrome, three hours after a Tc-99m methylene diphosphonate injection Focal increased uptake is seen in the right sacroiliac joint and sacral body, consistent with ... with fractures, and most likely representing the cause of the patient s pain Figure Anterior and posterior whole body bone scan views of a 46-year-old Caucasian man with Morquio s syndrome complaining ... References Morquio L: Sur une forme de dystrophie osseuse familiale Archives de medicine des infants 1929, 32:129-135 Prat C, Lemaire O, Bret J, Zabraniecki L, Fournié B: Morquio syndrome: diagnosis...
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Báo cáo khoa hoc:" Effectiveness of low-dose doxycycline (LDD) on clinical symptoms of Sjögren''''s Syndrome: a randomized, double-blind, placebo controlled cross-over study" potx
... symptoms (data not shown) Figure and scores VASseven of measured subjective symptoms in weeks one VAS scores of measured subjective symptoms in weeks one and seven * indicates statistically significant ... Apollonia, and Oulu University Hospital KEVO grants References Statistical analysis SPSS for Windows Release 11.5.1 (SPSS Inc., Chicago, IL, USA) was used for the statistical analysis Since the ... Negative Results in BioMedicine 2007, 6:11 of the disease is often stable with slow initiation and progression of sicca symptoms Primary SS is a separate disease entity, while secondary SS is concurrent...
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Báo cáo y học: "A possible variant of Bouveret’s syndrome presenting as a duodenal stump obstruction by a gallstone after Roux-en-Y gastrectomy: a case report" pot
... in these patients poses a significant risk of inadvertent gastrointestinal injury due to the presence of adhesions Bouveret s syndrome is a rare complication of gallstone disease [1], and is characterized ... and/ or endoscopy may confirm the diagnosis, and endoscopic disimpaction may be possible, but surgery is frequently necessary Cholecystectomy carries no benefit in these cases, and is often very ... to be successful, and may be an option for patients unfit for surgery [4] Surgical exploration of the common bile duct is necessary where endoscopic and percutaneous techniques are unsuccessful...
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Báo cáo y học: " Adrenocortical oncocytic neoplasm presenting with Cushing''''s syndrome: a case report" pot
... investigations revealed leukocytosis and normal serum electrolytes and normal fasting and post-prandial glucose levels Cushing' s syndrome was suspected, and further endocrinological tests were ... obviously malignant cases in which the diagnosis is based on common clinicopathologic features universally valid for tumors of any site, such as distant metastases, surgical unresectability and/ or ... neoplasm He was symptomatic and admitted to the hospital because of suspected Cushing' s syndrome The laboratory findings were compatible with the syndrome, and further investigation revealed a mass...
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Báo cáo y học: " Pathogenic effect of interleukin-17A in induction of Sjögren’s syndrome-like disease using adenovirus-mediated gene transfer" docx
... has been implicated in a growing Page of 11 list of autoimmune diseases, for example, multiple sclerosis, Crohn s disease, rheumatoid arthritis, psoriasis, systemic lupus erythematosus, and SS, ... Lakes, NJ, USA) and analyzed by FCS Express (De Novo Software, Los Angeles, CA, USA) Histology Following euthanasia, whole salivary glands containing submandibular, sublingual, and parotid glands ... these observations are consistent with the concept that SS develops along specific biological processes in a sequential fashion and interference with this process alters development of disease...
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Cushing’s Disease in Children: Report of Three Cases potx
... changes, may be the major complaints in children with Cushing s disease Two of our patients presented with such problems as initial symptoms Thus a high index of suspicion of Cushing s syndrome is ... serum cortisol levels with no diurnal changes Serum cortisol levels were not suppressed by lowdose dexamethasone in two of these patients (cases and 3) but serum cortisol levels were suppressed ... high in some children with Cushing s disease The results of dexamethasone suppression tests in children with Cushing s syndrome should thus be interpreted with caution After careful analysis of...
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báo cáo hóa học:" Rapid serological detection of autoantibodies associated with Sjögren''''s syndrome" docx
... including systemic lupus erythematosus (SLE), and myositis [7] Nevertheless, in the 2002 classification standards for SjS diagnosis, positive SSA and SSB autoantibody tests were the only mandatory ... positive cases These results suggest that QLIPS Ro52-Δ2 test shows similar sensitivity to an ELISA, but produces quicker and more robust results The Ro52-Δ2 QLIPS test in a new SjS cohort shows ... salivary gland biopsy are required for the diagnosis of primary SjS [6] This is because antibodies to SSA and SSB are not specific to SjS, but are also found in other rheumatological diseases...
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báo cáo hóa học: " Primary Sjögren''''s Syndrome: health experiences and predictors of health quality among patients in the United States" potx
... depression in PSS is consistent with that of previous studies Valtysdottir measured psychological status in a Swedish cohort (N = 67) of PSS patients and reported that possible depression was present ... details on this scale see Additional file 1, Table S1 ); and, depressed mood with the Center for Epidemiologic Studies Depression Scale(CESD) [16] The PROFAD-SSI was also used to assess sicca severity ... patients to select 100 patients at random and recruit them for the study Subjects recruited through the Sjogren 's foundation (SSF-PSS) were classified as "possible" PSS if they reported a diagnosis...
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Báo cáo y học: "Psychiatric disorder as clinical presentation of primary Sjögren’s syndrome: two case reports." pdf
... persistent fatigue, myalgia, and symptoms referred to her eyes (sandy feeling, itchiness, and burning sensation), mouth (dryness), and joints (pain and stiffness, mostly in the elbows and ankles) ... anti-La/SS-B is still unclear Ampelas et al [8] have also suggested that mental disorders in primary SS were explained by secondary psychological distress According to them, the slowly progressive and ... the psychiatric disorder In general, this consideration holds for all autoimmune diseases Psychiatric presentation of primary SS also suggests that mental disorders not occur only as a response...
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Báo cáo y học: "Abnormalities of B cell phenotype, immunoglobulin gene expression and the emergence of autoimmunity in Sjögren’s syndrome" pdf
... Bridts CH, Stevens WJ: Expression of CD5 and CD23 on B cells of patients with rheumatoid arthritis, systemic lupus erythematosus and Sjögren s syndrome Relationship with disease activity and treatment ... autoimmune diseases, such as pSS and SLE, seem to have characteristic abnormalities of particular censoring mechanisms IgV gene usage in patients with pSS is preferentially shaped by disordered selection ... Carsons SE, Daniels TE, Fox PC, Fox RI, Kassan SS, Pillemer SR, Talal N, Weisman MH: European Study Group on Classification Criteria for Sjögren s Syndrome Assessment of the European classification...
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Báo cáo y học: "Genetic control of disease in an experimental model for Sjögren’s syndrome Åsa Andersson" potx
... (mycobacterium-induced systemic lupus erythematosus 1) This might suggest shared disease pathways in different models for autoimmune diseases controlled by the same genes within this interval On the basis of potential ... locus, important in the homeostasis of lipids, lipoproteins, cholesterols, and fatty acids Secondary effects of impaired lipid homeostasis could result in inflammation and cell death Results from ... close to, candidate genes from susceptible and resistant mouse strains, speculations on disease mechanisms has to be considered preliminary The re-defined Aec2 locus could most likely be further...
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Báo cáo y học: "Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjögren''''s syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate" pptx
... autoimmune diseases such as RA and Crohn 's disease [13,28,29,39] make this cytokine a prime candidate also in the pathogenesis of SS Increased serum levels and salivary gland expression of IL18 ... with Sjögren 's syndrome (SS) (a–c,g–i) and in nonspecific chronic sialoadenitis (d–f) sialoadenitis (d–f) (a,b) Paraffin-embedded section of glands in SS, showing high amounts of IL-18-expressing ... GC-like structures identified as described in Materials and methods, and foci were classified as nonsegregated and segregated with or without GC-like structures drome (SS) (a–d) salivary gland ducts...
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Báo cáo y học: "Analysis of immunoglobulin light chain rearrangements in the salivary gland and blood of a patient with Sjögren’s syndrome" pptx
... Porter SR, Richards A, Sauvezie B, Schiodt M, Sciuto M, Shoenfeld Y, Skopouli FN, Smolen JS, Soromenho F, Tishler M, Wattiaux MJ: Assessment of the European classification criteria for Sjögren s syndrome ... with SS (nd, not determined; ns, not significant) observed for the Vλ repertoire, this suggests a positive selection of these mutations in the parotid gland Discussion The present study has identified ... Gellrich S, Rutz S, Borkowski A, Golembowski S, Gromnica-Ihle E, Sterry W, Jahn S: Analysis of VH-DJH gene transcripts in B cells infiltrating the salivary glands and lymph node tissue of patients with...
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