current advances in the treatment of major depression shift towards receptor specific drugs
Advances in the Treatment of Ischemic Stroke Edited by Maurizio Balestrino docx
... induces the synthesis of amino terminal consensus sequence RNA-binding domain proteins (CS-RBD) The “cold-inducible RNA-binding protein” (CIRP) is one of these proteins, and has been involved in protection ... metabolic insult Combination therapy is based in the extension of the therapeutic window of hypothermia using pharmacotherapy and establishes an interesting approach in hypothermia research 4.1 Hypothermia, ... multiple mechanisms of action in opposition to the consequences of ischemia 4 Advances in the Treatment of Ischemic Stroke Background of therapeutic hypothermia Cooling of the body for therapeutic purposes...
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ADVANCES IN THE TREATMENT OF ISCHEMIC STROKE pptx
... induces the synthesis of amino terminal consensus sequence RNA-binding domain proteins (CS-RBD) The “cold-inducible RNA-binding protein” (CIRP) is one of these proteins, and has been involved in protection ... metabolic insult Combination therapy is based in the extension of the therapeutic window of hypothermia using pharmacotherapy and establishes an interesting approach in hypothermia research 4.1 Hypothermia, ... multiple mechanisms of action in opposition to the consequences of ischemia 4 Advances in the Treatment of Ischemic Stroke Background of therapeutic hypothermia Cooling of the body for therapeutic purposes...
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Báo cáo y học: " Pregnancy and delivery while receiving vagus nerve stimulation for the treatment of major depression: a case report" pot
... Improvement in functioning is demonstrated by increases in GAF scores, beginning shortly after the start of VNS therapy and continuing through her pregnancy and delivery resolved without specific treatment ... 2003 Date of Assessment Figure continuing through her pregnancy and delivery Improvement in functioning is demonstrated by increases in GAF scores, beginning shortly after the start of VNS therapy ... enrollment in the VNS studies of patients with TRD, there have been no studies of the use of VNS therapy among pregnant patients A report of eight pregnancies in patients receiving VNS therapy for...
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Báo cáo y học: "Current approaches in the treatment of arthritic pain" pps
... goals for the management of both OA and RA include the prevention or amelioration of joint damage, the prevention of loss of function, and the reduction of pain [8,9] In the absence of complete ... the treatment of chronic pain, although there have been few studies assessing the efficacy of the technique for arthritic pain Underlying mechanisms of action remain unclear, but in studies of ... central-acting oral analgesic that has a unique dual mechanism of action involving both a weak µ-agonist action as well as inhibition of the reuptake of noradrenaline (norepinephrine) and serotonin It...
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Báo cáo y học: "Anti-inflammatory effects of antidepressant and atypical antipsychotic medication for the treatment of major depression and comorbid arthritis: a case report" pdf
... decline in pain and depressive symptoms while the activity levels increased continuously Moreover, the findings in this case report are less likely to be influenced by the effects of mirtazapine ... out in this area, thus leaving a lack of data on the potential anti-inflammatory effects of escitalopram despite a recent finding that escitalopram lowers the level of soluble interleukin receptor ... effectiveness of quetiapine in major depression [6] In the follow-up consultations in the mood disorder clinic it became apparent that her depressive symptoms were continuously improving, and following...
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Báo cáo y học: "The opposite effects of fluvoxamine and sertraline in the treatment of psychotic major depression: a case report" potx
... to clarify the role of sigma-1 receptors in the efficacy of fluvoxamine for psychotic major depression Consent The treatment of the reported case was made according to standard clinical practice; ... for the treatment of psychotic major depression using SSRI monotherapy One possible mechanism may be due to the difference in the action of these SSRIs at the endoplasmic reticulum protein sigma-1 ... psychopharmacology from that of other SSRIs [29] It is therefore possible that activation of the dopaminergic system by the inhibition of dopamine transporter may be involved in the mechanism of unwanted effects...
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Báo cáo y học: " Aripiprazole Augmentation in the Treatment of Military-Related PTSD with Major Depression: a retrospective chart review" docx
... [42] administered at intake and at each follow-up appointment over the course of treatment In addition to providing psychoeducation, the standard psychiatric treatment at the clinic includes ... administered by a trained clinician and the diagnosis of major depressive disorder was determined using the Patient Health Questionnaire (PHQ-9)[44] and the psychiatric interview according to the ... recently, the efficacy of aripiprazole in the treatment of PTSD has been demonstrated in three preliminary open-label studies in veteran populations, both as a monotherapy and as an adjunctive treatment...
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báo cáo khoa học: "R-CHOP versus R-CVP in the treatment of follicular lymphoma: a meta-analysis and critical appraisal of current literature" ppt
... of those met all inclusion criteria as studies of frontline or re -treatment Two of those four met the criteria for the first analysis (frontline treatment alone) Outcome The primary goal of the ... (53%) or R-CHOP (63%) The international PRIMA study testing the efficacy of maintenance therapy by rituximab may provide important data in the field of the best induction in patients with follicular ... classified as having no response, partial response (PR) or complete response (CR) The definitions of tumor response used in two of the studies were in accordance with the International Working Group...
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Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... 2004, of portacaval shunting, thereby decreasing first pass metabolism; decrease in quantities and affinity of plasma proteins, thereby increasing free-drug levels; increase in volume of distribution ... hrs following the post-dialysis dose There is a case report in which lithium levels were maintained in the therapeutic range by intraperitoneal administration of lithium during continuous peritoneal ... syndrome), including carbamazepine, phenytoin, phenobarbital, and lamotrigine The triad of hypersensitivity includes fever, rash and internal organ involvement with onset of symptoms within to weeks of...
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Báo cáo y học: "Technical Considerations in Decompressive Craniectomy in the Treatment of Traumatic Brain Injury"
... the angles of the dural opening The most significant step involves constructing small supporting pillars on the bilateral sides of the vessels as they pass the edge of the dural window (the pillars ... and in most reports the involved patient populations are small, these experiences are valuable At present, in the absence of definite proof of the efficacy of decompressive craniectomy in the treatment ... Following removal of part of the skull, they performed dural incisions in a stellate fashion In this step, it is important that entrance points of major vessels are close to the midpoint between the...
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Báo cáo y học: "Godoy & Godoy technique in the treatment of lymphedema for under-privileged populations."
... variations in working pressures of the main groups of muscles of the limbs whilst using compression mechanisms during exercising This is a new line of research that aims at developing facilitating devices ... technique aims at draining lymph (already in the collectors) and stimulating the formation of lymph (the flow of interstice fluid to the lymphatic capillaries) Increases in interstice pressures, ... which can be used in the control of exercising Eight devices have been developed that involve the main muscle groups with the objective of improving the mobility of joints and reducing trophic muscle...
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Báo cáo y học: " Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial"
... withdrawn from the study (without penalty) if, in the opinion of the treating physician, it was not in the patient’s best interest to continue For instance, if during the course of the study a patient ... unwilling to stop taking pain medication other than the study medication (for arthritis or other types of pain) or is unwilling to stop taking other medications for the treatment of OA Any other ... including glucosamine and chondroitin, one month prior to study and during the study, other than multivitamin and mineral supplements containing vitamins and minerals as the sole medicinal ingredients...
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Báo cáo y học: " Vacuum-assisted closure in the treatment of early hip joint infection"
... reduction, the V.A.C.-system is not often used in the treatment of prosthesis – related infections Currently, there exist only four reports about the use of the V.A.C – system in the infection ... overstrain the clearance function of the V.A.C.-therapy, thus being probably the reason for the system failure in the infection treatment in case 10 One limitation of our study is that we cannot define ... of an endoprosthesis involving the local tissue and causing an immune reaction [15] The most common problem hereby is the draining sinus, prolongating and preventing wound healing The pathophysiological...
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Báo cáo y học: " Two-stage procedure in the treatment of late chronic hip infections spacer"
... by the ratio in which the antibiotics are mixed into the cement and therefore, the total dose of antibiotics should not exceed 10% of the weight of the cement in order to avoid fracture of the ... safety The most commonly used antibiotics in ALC include tobramycin, gentamicin and vanco- 254 mycin [26] The combination of vancomycin and one of the aminoglycosides provides a broad spectrum of ... salvage of the infected hip: rationale for the use of gentamicin-impregnated cement and heads The hip proceedings of the thirteenth open scientific meeting of the hip society 1985; :65-94 Ensing...
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Báo cáo y học: "Complications after spacer implantation in the treatment of hip joint infections"
... remove the femoral stem For loading of the bone cement, the combination of gentamicin and vancomycin was most frequently used followed by the combination of gentamicin and teicoplanin Data about the ... http://www.medsci.org Int J Med Sci 2009, sion of the haematoma is an indispensable premise in the prevention of a wound infection Besides draining sinus, other infections during the two-stage protocol ... complications (draining sinus, pneumonia, etc.) Despite the retrospective design of our study and the limited possibility of interpreting these findings and their causes, this rate indicates that these patients...
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Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx
... not localize to the same cells in the brain, suggesting that they are functionally distinct Although Signaling mediators in the treatment of obesity CPT1c is highly expressed in the hypothalamus, ... previously, the brain is not a major user of long-chain fatty acids making a brain-specific isoform intriguing CPT1c was identified and cloned from in silico sequences as a highly homologous member of the ... promoting an increase in proopiomelanocortin and cocaine and amphetamine regulated transcript Taken together, these findings provide a compelling argument for the role for malonyl-CoA in regulating...
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Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc
... suggesting that these cyclin-dependent kinase inhibitors are important in the regulation of adipocyte number The S-phase kinase-associated protein (Skp)1–CullinF-box protein (SCF) ubiquitin ligase ... at each phase of the cell cycle by various complexes of cell-cycle-related molecules, including cyclins, cyclin-dependent kinases, their inhibitors and the retinoblastoma protein (RB), as well ... clinical course of some types of obesity In this minireview, we focus on adipocyte hyperplasia as a novel therapeutic target for the treatment of obesity and discuss the merits of targeting recQ-mediated...
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Role of Corticosteroids in the Treatment of Tuberculosis: An Evidence-based Update potx
... risk of recurrent TB CORTICOSTEROIDS IN OTHER FORMS OF EXTRAPULMONARY TB Credible evidence from clinical trials for the use of corticosteroids in other infrequent forms of TB, such as genitourinary ... imaging of the brain was also performed in a subset of patients in this study.36 It was found that use of corticosteroids possibly reduced the risk of developing hydrocephalus and vasculitic infarcts; ... corticosteroids in TB, specifically TBM, the exact mechanisms of such benefit remain poorly understood 40 Thwaites et al 11 have put forward an interesting hypothesis to explain the clinical benefit of corticosteroids...
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Managing Drug Interactions in the Treatment of HIV-Related Tuberculosis docx
... antiretroviral drugs progress become available The Role of Rifamycins in Tuberculosis Treatment Despite the complexity of these drug interactions, the key role of the rifamycins in the success of tuberculosis ... 8, Predicting Drug Interactions Involving Rifamycins Knowledge of the mechanisms of drug interactions can help predict the likelihood of an interaction, if that specific combination of drugs has ... evaluated The rifamycin class upregulate (induce) the synthesis of several classes of drug transporting and drug metabolizing enzymes With increased synthesis, there is increased total activity of the...
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